339504

antibody from BioLegend
Targeting: KIR2DL3 CD158B2, cl-6, nkat2, nkat2a, nkat2b, p58
Provider product page for 339504

Antibody data

Product number
339504 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#339504, RRID:AB_2130378
Product name
FITC anti-human CD158a/h (KIR2DL1/S1)
Antibody type
Monoclonal
Antigen
Human NK cell clone LB2
Description
CD158 molecules, also known as KIRs (killer cell immunoglobulin-like receptors), are a family of transmembrane proteins with either two (KIR2D) or three (KIR3D) Ig-like extracellular domains. Some KIRs with long cytoplasmic domains contain ITIMs and posses inhibitory functions and others with short cytoplasmic region lack ITIM and have activation functions. 14 polymorphic KIR genes have been reported in humans. CD158 is mainly expressed on a subset of NK cells and a small population of CD8+ T cells. The mAb HP-MA4 reacts with KIR2DL1 (CD158a) and KIR2DS1 (CD158h). HLA-C is the ligand of CD158a/h.
Reactivity
Human
Host
Mouse
Conjugate
Green dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
KIR2DL3 protein structure - 339504 shown in red.