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Learn66231-2-Ig
antibody from Proteintech Group
Targeting: CD68
DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [132]
- Comments [0]
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- Product number
- 66231-2-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- CD68 antibody
- Antibody type
- Monoclonal
- Description
- CD68 antibody (Cat. #66231-2-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3A9A7
- Vial size
- 20ul, 150ul
Submitted references Mapping Immune-Inflammatory Niches on Zirconia Bone Implants: Single-Cell Transcriptomic Profiling.
Nanoparticle-Loaded Injectable Hydrogel Alleviates Titanium Particle-Induced Osteolysis by Disrupting GATA6/DDX3X-Mediated Macrophage Inflammation.
RP-182 alleviated obstruction-induced renal fibrosis by reprogramming CD206(+) macrophages.
Linderalactone mitigates diabetic renal injury by inhibiting macrophage inflammation via the Dectin1/Syk/CARD9/IRF5/NF-κB pathway.
Type I interferon-induced CD169(+) macrophages play a protective role in periodontitis.
A preliminary single-cell map of endometriosis suggests roles for fibroblast metabolism and macrophage polarization in disease progression.
Fibroblast-derived exosomes induce macrophage pyroptosis to mediate orthodontic bone remodeling through the mtDNA/NLRP3 axis.
Indole metabolites produced by Lactobacillus acidophilus impedes bisphenol F- aryl hydrocarbon receptor interaction and ameliorates bisphenol F induced depression-like changes.
S100A8/A9 promotes renal fibrosis by driving macrophage-to-myofibroblast transition via the TLR4/NF-κB pathway.
Curcumin modulates the function of SPP1+ macrophages via NF-κB signaling to alleviate endometriosis.
Consolidative Radical Cystectomy Following Neoadjuvant Tislelizumab Plus Gemcitabine and Cisplatin in Clinically Lymph Node-positive Bladder Cancer: A Prospective Study.
A Pseudo-Mytilus Edulis Foot Protein-Based Hydrogel Adhesive with Osteo-Vascular-Immune Coupling Effects for Osteoporotic Bone-Implant Integration.
Downregulation of the biological macromolecule Spondin-2 disrupts maternal-fetal immune tolerance and trophoblast invasion, driving unexplained recurrent pregnancy loss.
CA9+ cancer-associated fibroblasts cooperate with SPP1+ tumor-associated macrophages driving immune resistance in triple-negative breast cancer.
METTL3 abrogation promotes glioma progression through regulating the ISG15-FASN axis-mediated lipid metabolism in macrophages.
Effect and Mechanism of Apoptotic Bodies from Inflammatory Periodontal Ligament Stem Cells on Macrophage M1 Polarisation.
Paclitaxel drives TREM2(+) macrophage expansion underlying its inferior therapeutic efficacy compared to Nab-paclitaxel.
The pro-cancer and immunosuppressive activity of macrophage-transformed cancer-associated fibroblasts in oral squamous cell carcinoma.
CCR1(hi)/CCL5(hi) macrophage-mediated CCL5(hi) T cell chemotaxis in salivary gland aggravates Sjögren's syndrome.
Multidimensional Oriented Piezoelectric Conduits for Peripheral Nerve Defect Regeneration.
SpaHE-Infil: A spatial heterogeneity framework for decoding TME infiltration from H&E-stained slides.
Targeting Smad3 Phosphorylation Attenuates Anastomotic Intimal Hyperplasia and Perigraft Fibrosis in Decellularized Tissue-Engineered Vascular Grafts.
Tumor-associated macrophages drive heterogenetic CD10(High) cancer stem cells to implement tumor-associated neutrophils reprogramming in oral squamous cell carcinoma.
DPP7 promotes fatty acid β-oxidation in tumor-associated macrophages and determines immunosuppressive microenvironment in colorectal cancer.
PGAM5 Modulates Macrophage Polarization, Aggravating Inflammation in COPD via the NF-κB Pathway.
Macrophage Tim-4 protects against deep vein thrombosis by binding CK2β to suppress inflammatory responses.
Advanced aggressive clinical features may be associated with immune dysfunction in patients with HIV-positive Hodgkin lymphoma in the cART era: a multicenter study from China.
Comprehensive multiomics analysis identifies PYCARD as a key pyroptosis-related gene in osteoarthritis synovial macrophages.
Inhibitors of KAT2A Alleviate the Progression of AKI by Alleviating Macrophage Ferritinophagy.
Pan-cancer analysis and experimental validation revealed that prognostic biomarker APOBEC3C may promote M2-type macrophage polarization and prevent R-loop accumulation in glioma.
Primary culture of inner ear schwannoma.
Self-assembled extracellular matrix-lipid nanoparticle composite for site-specific siRNA delivery to improve cardiac repair post-myocardial infarction.
Tumor-draining lymph nodes respond to immune checkpoint inhibition and orchestrate tumor immune remodeling.
The Bcl-2 family protein NOXA is a novel regulator of liver regeneration.
Three-Dimensional-Printed In Vitro Model of Colorectal Cancer with Immune Microenvironment and Reprogramming Capabilities.
DAPK1-positve macrophages facilitate immunosuppressive microenvironment and determine immunotherapy efficacy in colorectal cancer.
Blocking CCR1(+) macrophages overcomes resistance to immune checkpoint inhibitors in melanoma.
Pharmacological targeting cGAS/STING/NF-κB axis by tryptanthrin induces microglia polarization toward M2 phenotype and promotes functional recovery in a mouse model of spinal cord injury.
Human efferent ductules and epididymis display unique cell lineages with motile and primary cilia.
SPP1 (+) macrophages in colorectal cancer: Markers of malignancy and promising therapeutic targets.
Senescent macrophages induce ferroptosis in skeletal muscle and accelerate osteoarthritis-related muscle atrophy.
Zwitterionic Brush-Grafted Interfacial Bio-Lubricant Evades Complement C3-Mediated Macrophage Phagocytosis for Osteoarthritis Therapy.
The Activation of the Microglial NLRP3 Inflammasome Is Involved in Tuberous Sclerosis Complex-Related Neuroinflammation.
Impact of the PD-1/PD-L1 inhibitor SCL-1 on MDA-MB231 tumor growth in a humanized MHC-double knockout NOG mouse model.
Characteristics of cancer mycobiome in patients with acral melanoma.
Adventitial Injection of Hyaluronic Acid/Sodium Alginate Hydrogel Loaded With IL-33 Antibody Decreases Neointimal Hyperplasia.
Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling.
Deubiquitinase JOSD2 alleviates colitis by inhibiting inflammation via deubiquitination of IMPDH2 in macrophages.
The CC motif chemokine ligand 11 contributes to alcoholic liver disease.
PANAXADIOL SAPONIN ALLEVIATES LPS-INDUCED CARDIOMYOPATHY SIMILAR TO DEXAMETHASONE VIA IMPROVING MITOCHONDRIAL QUALITY CONTROL.
Farrerol confers neuroprotection in spinal cord injury by regulating macrophages/microglia polarization through the JAK2/STAT3 pathway.
Macrophage-related immune responses to polyetherketoneketone bone implants: Single-cell transcriptome analysis.
Synovium-On-A-Chip: Simulating the Microenvironment of the Rheumatoid Arthritis Synovium via Multicell Interactions to Target Fibroblast-Like Synoviocytes.
IRF7 orchestrates proinflammatory macrophage polarization and joint destruction in rheumatoid arthritis.
Alpha-1 Antitrypsin Mediates Spontaneous Resolution of Acute Gouty Inflammation Via Inhibiting Caspase 3/GSDME-dependent Macrophage Pyroptosis.
Sappanone A Promotes Motor Function Recovery in Spinal Cord Injury Mice by Inhibiting Microglial M1 Polarization via Activation of the Keap1/Nrf2 Pathway.
Cryopreservable, scalable and ready-to-use cell-laden patches for diabetic ulcer treatment.
C-Reactive Protein to Lymphocyte Ratio (CLR) and Lactate Dehydrogenase to Albumin Ratio (LAR) as Prognostic Biomarkers in Acral Melanoma: Association With Tertiary Lymphoid Structures and Immune Cell Infiltration.
The foam cell-derived exosomes exacerbate ischemic white matter injury via transmitting metabolic defects to microglia.
High ELK3 expression is associated with the wild type IDH1 in glioma and enhances infiltration of M2 macrophages.
Drp1 Promotes Macrophage M1 Polarization and Inflammatory Response in Autoimmune Myocarditis by Driving Mitochondrial Fission.
Localization of epidermal growth factor receptor-mutations using PNA:DNA probes in clinical specimens from patients with non-small cell lung cancer.
Microneedle delivery of CAR-M-like engineered macrophages alleviates intervertebral disc degeneration through enhanced efferocytosis capacity.
Analysis of clinical significance and molecular characteristics of methionine metabolism and macrophage-related patterns in hepatocellular carcinoma based on machine learning.
Recruitment and polarization typing of tumor-associated macrophages is associated with tumor progression and poor prognosis in Wilms tumor patients.
Single-cell sequencing analysis reveals cancer-associated pericyte subgroup in esophageal squamous cell carcinoma to predict prognosis.
Identification of a distinct cluster of GDF15(high) macrophages induced by in vitro differentiation exhibiting anti-inflammatory activities.
STAC3 as a poor prognostic biomarker in renal clear cell carcinoma: relationship with immune infiltration.
Tumor cell senescence-induced macrophage CD73 expression is a critical metabolic immune checkpoint in the aging tumor microenvironment.
Intratumoral microbiota as a novel prognostic indicator in bladder cancer.
Macrophage SHP2 Deficiency Alleviates Diabetic Nephropathy via Suppression of MAPK/NF-κB- Dependent Inflammation.
Impact of intratumoral microbiome on tumor immunity and prognosis in human pancreatic ductal adenocarcinoma.
RSK4 promotes the macrophage recruitment and M2 polarization in esophageal squamous cell carcinoma.
Wireless Electric Cues Mediate Autologous DPSC-Loaded Conductive Hydrogel Microspheres to Engineer the Immuno-Angiogenic Niche for Homologous Maxillofacial Bone Regeneration.
Increase in GPIHBP1 expression in advanced stage colorectal cancer indicates poor immune surveillance.
Dectin1 contributes to hypertensive vascular injury by promoting macrophage infiltration through activating the Syk/NF-κB pathway.
Biodegradable Cardiac Occluder with Surface Modification by Gelatin-Peptide Conjugate to Promote Endogenous Tissue Regeneration.
Inhibition of heme oxygenase 1 alleviates thoracic aortic aneurysm via restoration of extracellular matrix.
VR23 and Bisdemethoxycurcumin Enhanced Nanofiber Niche with Durable Bidirectional Functions for Promoting Wound Repair and Inhibiting Scar Formation.
LncRNA sequencing reveals an essential role for the lncRNA-mediated ceRNA network in penile squamous cell carcinoma.
Berberine modulates microglial polarization by activating TYROBP in Alzheimer's disease.
A novel protein encoded by circLARP1B promotes the proliferation and migration of vascular smooth muscle cells by suppressing cAMP signaling.
Mzb1 Attenuates Atherosclerotic Plaque Vulnerability in ApoE-/- Mice by Alleviating Apoptosis and Modulating Mitochondrial Function.
The influence of CLEC5A on early macrophage-mediated inflammation in COPD progression.
Endothelial cell heterogeneity in colorectal cancer: tip cells drive angiogenesis.
The relationship of ALPK1, hyaluronic acid and M1 macrophage polarization in the temporomandibular joint synovitis.
Diaphorobacter nitroreducens synergize with oxaliplatin to reduce tumor burden in mice with lung adenocarcinoma.
Hepatocellular carcinoma subtypes based on metabolic pathways reveals potential therapeutic targets.
A pan-cancer single-cell panorama of human natural killer cells.
Low-dose adropin stimulates inflammasome activation of macrophage via mitochondrial ROS involved in colorectal cancer progression.
Localized delivery of anti-inflammatory agents using extracellular matrix-nanostructured lipid carriers hydrogel promotes cardiac repair post-myocardial infarction.
Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages.
Tanshinone IIA enhances the therapeutic efficacy of mesenchymal stem cells derived exosomes in myocardial ischemia/reperfusion injury via up-regulating miR-223-5p.
ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression.
An N6-methyladenosine regulation- and mRNAsi-related prognostic index reveals the distinct immune microenvironment and immunotherapy responses in lower-grade glioma.
Aprepitant inhibits the progression of esophageal squamous cancer by blocking the truncated neurokinin‑1 receptor.
Methylene blue targets PHD3 expression in murine microglia to mitigate lipopolysaccharide-induced neuroinflammation and neurocognitive impairments.
Macrophages and derived-TNF-α promote lipopolysaccharide-induced upregulation of endogenous β-glucuronidase in the epithelial cells of the bile duct: A possible facilitator of hepatolithiasis formation.
Parasympathetic-macrophages-ductal epithelial cells axis promotes female rat submandibular gland regeneration after excretory duct ligation/deligation.
GSDME-mediated pyroptosis promotes the progression and associated inflammation of atherosclerosis.
ASGR1 promotes liver injury in sepsis by modulating monocyte-to-macrophage differentiation via NF-κB/ATF5 pathway.
UBC9 deficiency enhances immunostimulatory macrophage activation and subsequent antitumor T cell response in prostate cancer.
Single-cell multi-omics analysis of human testicular germ cell tumor reveals its molecular features and microenvironment.
Purinergic receptor P2X7 contributes to abdominal aortic aneurysm development via modulating macrophage pyroptosis and inflammation.
Inhibition of IL-4/STAT6/IRF4 signaling reduces the epithelial-mesenchymal transition in eosinophilic chronic rhinosinusitis with nasal polyps.
Single-cell and spatial analyses reveal the association between gene expression of glutamine synthetase with the immunosuppressive phenotype of APOE+CTSZ+TAM in cancers.
Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.
YTHDF1 Negatively Regulates Treponema pallidum-Induced Inflammation in THP-1 Macrophages by Promoting SOCS3 Translation in an m6A-Dependent Manner.
Single-cell RNA sequencing reveals TCR(+) macrophages in HPV-related head and neck squamous cell carcinoma.
Heparin binding epidermal growth factor-like growth factor is a prognostic marker correlated with levels of macrophages infiltrated in lung adenocarcinoma.
ICOS-Positive Regulatory T Cells in Hepatocellular Carcinoma: The Perspective from Digital Pathology Analysis.
Identifying potential signatures for atherosclerosis in the context of predictive, preventive, and personalized medicine using integrative bioinformatics approaches and machine-learning strategies.
An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation.
Blockade of Kv1.3 Potassium Channel Inhibits Microglia-Mediated Neuroinflammation in Epilepsy.
The Immunological Contribution of a Novel Metabolism-Related Signature to the Prognosis and Anti-Tumor Immunity in Cervical Cancer.
Increased co-expression of MEST and BRCA1 is associated with worse prognosis and immune infiltration in ovarian cancer.
Construction and analysis of a ceRNA network and patterns of immune infiltration in chronic rhinosinusitis with nasal polyps: based on data mining and experimental verification.
Multifunctional chitin-based hollow nerve conduit for peripheral nerve regeneration and neuroma inhibition.
SIGLEC15 amplifies immunosuppressive properties of tumor-associated macrophages in pancreatic cancer.
Ligustrazine Alleviate Acute Lung Injury Through Suppressing Pyroptosis and Apoptosis of Alveolar Macrophages.
Novel roles of VAT1 expression in the immunosuppressive action of diffuse gliomas.
PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice.
Redox-sensitive activation of CCL7 by BRG1 in hepatocytes during liver injury.
The Protective Role of Yin-Yang 1 in Cardiac Injury and Remodeling After Myocardial Infarction.
Berberine exerts anti-tumor activity in diffuse large B-cell lymphoma by modulating c-myc/CD47 axis.
The downregulation of NCXs is positively correlated with the prognosis of stage II-IV colon cancer.
Lung Myofibroblasts Promote Macrophage Profibrotic Activity through Lactate-induced Histone Lactylation.
Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy.
Saikosaponin-d attenuated lipopolysaccharide-induced depressive-like behaviors via inhibiting microglia activation and neuroinflammation.
Noncoding RNA 886 alleviates tumor cellular immunological rejection in host C57BL/C mice.
Tumor-associated macrophages (TAMs) depend on Shp2 for their anti-tumor roles in colorectal cancer.
Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression.
Zhou J, Li A, Chen J, Dai J, Zhang W, Yang Z, Li P
Research (Washington, D.C.) 2026;9:1162
Research (Washington, D.C.) 2026;9:1162
Nanoparticle-Loaded Injectable Hydrogel Alleviates Titanium Particle-Induced Osteolysis by Disrupting GATA6/DDX3X-Mediated Macrophage Inflammation.
Lin S, Liu T, Zhu Q, Ouyang Z, Yu Y, Sun H, Li C, Li S, Pan C, Ko WC, Liu H, Liu J, Li S, Chen J, Wu S, Ye J, Gao L, Ding Y
Biomaterials research 2026;30:0353
Biomaterials research 2026;30:0353
RP-182 alleviated obstruction-induced renal fibrosis by reprogramming CD206(+) macrophages.
Cao H, Chen X, Jin R, Yang Y, Tao Y, Li P, Wu Y, Chen G, Zhao J, Wen J, Zhao Y, Wei L, Wei Z, Lu D, Chen Y, Liu D, Zhou H, Cheng J
Frontiers in pharmacology 2026;17:1739457
Frontiers in pharmacology 2026;17:1739457
Linderalactone mitigates diabetic renal injury by inhibiting macrophage inflammation via the Dectin1/Syk/CARD9/IRF5/NF-κB pathway.
Chen H, Xu S, Chen B, Xiong X, Hu J, Wu Y, Wang T, Wang H
Journal of diabetes investigation 2026 Mar;17(3):395-410
Journal of diabetes investigation 2026 Mar;17(3):395-410
Type I interferon-induced CD169(+) macrophages play a protective role in periodontitis.
Lu J, Xiong Z, Wu X, Yang Y, Zhang J, Luo L
Journal of periodontology 2026 Mar 6;
Journal of periodontology 2026 Mar 6;
A preliminary single-cell map of endometriosis suggests roles for fibroblast metabolism and macrophage polarization in disease progression.
Cao X, Tao H, Fan X, Wang Y, Yang J, Zhou W, Xue P, Zhu P
Functional & integrative genomics 2026 Mar 31;26(1)
Functional & integrative genomics 2026 Mar 31;26(1)
Fibroblast-derived exosomes induce macrophage pyroptosis to mediate orthodontic bone remodeling through the mtDNA/NLRP3 axis.
Yu Q, Guo K, Yang Y, Liu H, Han Y, Yu X, Wang J, Zhao Y, Su X, Zhu K, Zheng S, Wang S, Li W, Huang Y
Journal of nanobiotechnology 2026 Mar 14;24(1)
Journal of nanobiotechnology 2026 Mar 14;24(1)
Indole metabolites produced by Lactobacillus acidophilus impedes bisphenol F- aryl hydrocarbon receptor interaction and ameliorates bisphenol F induced depression-like changes.
Hu M, Manglike A, Li X, Wei J, Lou X, Liu J, Tang Z, He W, Ji G, Wang W, Ma T, Gao R, Wang J
Journal of hazardous materials 2026 Jun 15;511:142150
Journal of hazardous materials 2026 Jun 15;511:142150
S100A8/A9 promotes renal fibrosis by driving macrophage-to-myofibroblast transition via the TLR4/NF-κB pathway.
Chen X, Zha W, Shen J, Li L, Fu Y, Tian P, Zheng B, Li C
International immunopharmacology 2026 Jun 15;179:116646
International immunopharmacology 2026 Jun 15;179:116646
Curcumin modulates the function of SPP1+ macrophages via NF-κB signaling to alleviate endometriosis.
Zong C, Xu J, Jiang Q, Yuan X, Gu R, Chen Y, Zhang B, Yu M, Lin C
International immunopharmacology 2026 Jul 1;180:116644
International immunopharmacology 2026 Jul 1;180:116644
Consolidative Radical Cystectomy Following Neoadjuvant Tislelizumab Plus Gemcitabine and Cisplatin in Clinically Lymph Node-positive Bladder Cancer: A Prospective Study.
Zhuang J, Yu H, Cao Q, Bai R, Feng T, Cai L, Yang X, Lu Q
European urology open science 2026 Jan;83:36-45
European urology open science 2026 Jan;83:36-45
A Pseudo-Mytilus Edulis Foot Protein-Based Hydrogel Adhesive with Osteo-Vascular-Immune Coupling Effects for Osteoporotic Bone-Implant Integration.
Wang W, Li Z, Zhang S, Ma Y, Yu L, Zhang Q, Pan G, Geng D, Zhu C, Bai J
Advanced materials (Deerfield Beach, Fla.) 2026 Jan;38(6):e11840
Advanced materials (Deerfield Beach, Fla.) 2026 Jan;38(6):e11840
Downregulation of the biological macromolecule Spondin-2 disrupts maternal-fetal immune tolerance and trophoblast invasion, driving unexplained recurrent pregnancy loss.
Zhang X, Li PF, Gao Y, Zheng PS
International journal of biological macromolecules 2026 Jan;338(Pt 1):149672
International journal of biological macromolecules 2026 Jan;338(Pt 1):149672
CA9+ cancer-associated fibroblasts cooperate with SPP1+ tumor-associated macrophages driving immune resistance in triple-negative breast cancer.
Ma Q, Wang J, Jiang Q
Cellular and molecular life sciences : CMLS 2026 Jan 9;83(1):54
Cellular and molecular life sciences : CMLS 2026 Jan 9;83(1):54
METTL3 abrogation promotes glioma progression through regulating the ISG15-FASN axis-mediated lipid metabolism in macrophages.
Yin H, Yu X, Hu C, Yang Y, Wang M, Xing Y, Zuo B, Zhang C, Yang W, Li Y, Yin Z, Zhao L, Ma H, Chen Y, Wang C, Ju Z, Liu B, Song M, Chai X, Wang F, Yang A, Zhang R
Nature communications 2026 Jan 8;17(1):1326
Nature communications 2026 Jan 8;17(1):1326
Effect and Mechanism of Apoptotic Bodies from Inflammatory Periodontal Ligament Stem Cells on Macrophage M1 Polarisation.
Weng J, Zhang Z, Zeng L, Xia J, Xu Z, Zhu G, Zhang H, Wang J, Pathak JL, Yu L
International dental journal 2026 Feb;76(1):103981
International dental journal 2026 Feb;76(1):103981
Paclitaxel drives TREM2(+) macrophage expansion underlying its inferior therapeutic efficacy compared to Nab-paclitaxel.
Xing Y, Zhong R, Li Q, Duan X, Xu M, Yu M, Liu C, He J, Sun Y, Wang Y, Guo X, Xu Y, Mo H, Ma F, Zhang H, Zhan J
Nature communications 2026 Feb 3;17(1)
Nature communications 2026 Feb 3;17(1)
The pro-cancer and immunosuppressive activity of macrophage-transformed cancer-associated fibroblasts in oral squamous cell carcinoma.
Tian H, Zhao S, Nie F, Yin Q, Wang S, Liu J, Ju J, Yang P, Yang C
Journal of advanced research 2026 Apr;82:521-534
Journal of advanced research 2026 Apr;82:521-534
CCR1(hi)/CCL5(hi) macrophage-mediated CCL5(hi) T cell chemotaxis in salivary gland aggravates Sjögren's syndrome.
Zhou J, Huang Y, Xiao D, Liu D, Chen X, Pan Z, Wang L, Watanabe N, Pathak JL, Li J
Journal of advanced research 2026 Apr;82:507-520
Journal of advanced research 2026 Apr;82:507-520
Multidimensional Oriented Piezoelectric Conduits for Peripheral Nerve Defect Regeneration.
Qi T, Wang X, Wu L, Han M, Zhou C, Wu B, Pei X, He C
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(22):e14376
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(22):e14376
SpaHE-Infil: A spatial heterogeneity framework for decoding TME infiltration from H&E-stained slides.
Wang F, Xu H, Wang X, Wu M, Ding S, Duan L, Yang C, Li J, Ge X, Qin Y, Qi X, Mao Y
iScience 2026 Apr 17;29(4):115155
iScience 2026 Apr 17;29(4):115155
Targeting Smad3 Phosphorylation Attenuates Anastomotic Intimal Hyperplasia and Perigraft Fibrosis in Decellularized Tissue-Engineered Vascular Grafts.
Lu P, Wang T, Liao S, He Z, Cheng S, Wang T, Cheng Z, An Y, Zhou S, Wang M, Zhang Q, Shu C
Biomaterials research 2025;29:0241
Biomaterials research 2025;29:0241
Tumor-associated macrophages drive heterogenetic CD10(High) cancer stem cells to implement tumor-associated neutrophils reprogramming in oral squamous cell carcinoma.
You Y, Du Z, Tian Z, Li S, Yu F, Xiao M, He Y, Wang Y
International journal of biological sciences 2025;21(3):1110-1126
International journal of biological sciences 2025;21(3):1110-1126
DPP7 promotes fatty acid β-oxidation in tumor-associated macrophages and determines immunosuppressive microenvironment in colorectal cancer.
Chang J, Niu Y, Zhou S, Zhu W, Zhang Z, Xiu H, Shang K, Feng Q, Wei Y
International journal of biological sciences 2025;21(14):6305-6325
International journal of biological sciences 2025;21(14):6305-6325
PGAM5 Modulates Macrophage Polarization, Aggravating Inflammation in COPD via the NF-κB Pathway.
Zheng Y, Wang Y, Li J, Zheng S, Zhang L, Li Q, Ling F, Nie Q, Feng Q, Wang J, Jin C
International journal of chronic obstructive pulmonary disease 2025;20:551-564
International journal of chronic obstructive pulmonary disease 2025;20:551-564
Macrophage Tim-4 protects against deep vein thrombosis by binding CK2β to suppress inflammatory responses.
Wang X, Zhang Z, Zheng W, Zhang B, Chu C, Chen J, Liu C, Xu K, Yu Z, Guo Q, Zhao S, Chen X, Bai F, Wang B, Li X, Liu W
Frontiers in immunology 2025;16:1634230
Frontiers in immunology 2025;16:1634230
Advanced aggressive clinical features may be associated with immune dysfunction in patients with HIV-positive Hodgkin lymphoma in the cART era: a multicenter study from China.
Liang X, Wang C, Tang Y, Xie X, Wu Y, Min H, Zhang W, Zhou W, Adhikari VP, Zhang X, Liu Y
Frontiers in immunology 2025;16:1628909
Frontiers in immunology 2025;16:1628909
Comprehensive multiomics analysis identifies PYCARD as a key pyroptosis-related gene in osteoarthritis synovial macrophages.
Yao Z, Li Y, Mai H, Wang Z, Zhang H, Cai D, Wang X
Frontiers in immunology 2025;16:1558139
Frontiers in immunology 2025;16:1558139
Inhibitors of KAT2A Alleviate the Progression of AKI by Alleviating Macrophage Ferritinophagy.
Zuo Z, Gao S, Wang J, Liu Z, Lu Z, Wu H, Huang X, Yang C, Chen J, Liu H, Pan Q, Yang L
ImmunoTargets and therapy 2025;14:1515-1529
ImmunoTargets and therapy 2025;14:1515-1529
Pan-cancer analysis and experimental validation revealed that prognostic biomarker APOBEC3C may promote M2-type macrophage polarization and prevent R-loop accumulation in glioma.
Yin W, Kuang Y, Xin Z, Huang H, Cao Y, Liu W, Wang L, Ren C, Jiang X
International journal of biological macromolecules 2025 Sep;322(Pt 1):146490
International journal of biological macromolecules 2025 Sep;322(Pt 1):146490
Primary culture of inner ear schwannoma.
Scheffler J, Liebau A, Lehner E, Leisz S, Koitzsch S, Reiber J, Harder A, Plontke SK
Journal of neuroscience methods 2025 Oct;422:110515
Journal of neuroscience methods 2025 Oct;422:110515
Self-assembled extracellular matrix-lipid nanoparticle composite for site-specific siRNA delivery to improve cardiac repair post-myocardial infarction.
Wang X, Zhong Y, Qian B, Huang S, Long Q, Zhang H, Zhao Q, Ye X
Materials today. Bio 2025 Oct;34:102205
Materials today. Bio 2025 Oct;34:102205
Tumor-draining lymph nodes respond to immune checkpoint inhibition and orchestrate tumor immune remodeling.
Zhang J, Ma J, Niu Y, Liu J, Wang Z, Guo J, Meng Y, Sun R, Zhang Z, Liu H, Xu J, Zan L, Guan X, Wang X
Cancer immunology, immunotherapy : CII 2025 Oct 6;74(11):326
Cancer immunology, immunotherapy : CII 2025 Oct 6;74(11):326
The Bcl-2 family protein NOXA is a novel regulator of liver regeneration.
Liu H, Ren W, Kuang Y, Gong S, Lin Z, Gong W, Miao X
Life sciences 2025 Oct 15;379:123874
Life sciences 2025 Oct 15;379:123874
Three-Dimensional-Printed In Vitro Model of Colorectal Cancer with Immune Microenvironment and Reprogramming Capabilities.
Liu H, Shi X, Wang D, Zhang H, Xu Z, Tan Z
ACS biomaterials science & engineering 2025 Oct 13;11(10):5991-6003
ACS biomaterials science & engineering 2025 Oct 13;11(10):5991-6003
DAPK1-positve macrophages facilitate immunosuppressive microenvironment and determine immunotherapy efficacy in colorectal cancer.
Chang J, Niu Y, Zhou S, Zhang Z, Zhu W, Zhu J, Xiu H, Shang K, Feng Q, Wei Y
Journal of translational medicine 2025 Nov 4;23(1):1220
Journal of translational medicine 2025 Nov 4;23(1):1220
Blocking CCR1(+) macrophages overcomes resistance to immune checkpoint inhibitors in melanoma.
Su X, Huang R, Kang D, Wang J, Li L, Zou Z
Cell communication and signaling : CCS 2025 Nov 3;23(1):475
Cell communication and signaling : CCS 2025 Nov 3;23(1):475
Pharmacological targeting cGAS/STING/NF-κB axis by tryptanthrin induces microglia polarization toward M2 phenotype and promotes functional recovery in a mouse model of spinal cord injury.
Fan Z, Jia M, Zhou J, Zhu Z, Wu Y, Lin X, Qian Y, Lian J, Hua X, Dong J, Fang Z, Liu Y, Chen S, Xue X, Yue J, Zhu M, Wang Y, Huang Z, Teng H
Neural regeneration research 2025 Nov 1;20(11):3287-3301
Neural regeneration research 2025 Nov 1;20(11):3287-3301
Human efferent ductules and epididymis display unique cell lineages with motile and primary cilia.
Vinay L, Hess RA, Belleannée C
Andrology 2025 May;13(4):894-910
Andrology 2025 May;13(4):894-910
SPP1 (+) macrophages in colorectal cancer: Markers of malignancy and promising therapeutic targets.
Xie Z, Zheng G, Niu L, Du K, Li R, Dan H, Duan L, Wu H, Ren G, Dou X, Dai S, Feng F, Zhang J, Zheng J
Genes & diseases 2025 May;12(3):101340
Genes & diseases 2025 May;12(3):101340
Senescent macrophages induce ferroptosis in skeletal muscle and accelerate osteoarthritis-related muscle atrophy.
Xiang W, Zhang T, Li B, Li S, Zhang B, Fang S, Chen L, Gong Y, Huang B, Feng D, Wu J, Yuan J, Wu Y, Yan X, Jin R, Zhang X, Fang X, Lian J, Chen L, Zhou S, Ni Z
Nature aging 2025 Jul;5(7):1295-1316
Nature aging 2025 Jul;5(7):1295-1316
Zwitterionic Brush-Grafted Interfacial Bio-Lubricant Evades Complement C3-Mediated Macrophage Phagocytosis for Osteoarthritis Therapy.
Cai C, Wang M, Wang L, Guo J, Wang L, Zhang Y, Wu G, Hua B, Stuart MAC, Guo X, Cao L, Yan Z
Advanced materials (Deerfield Beach, Fla.) 2025 Jul;37(28):e2501137
Advanced materials (Deerfield Beach, Fla.) 2025 Jul;37(28):e2501137
The Activation of the Microglial NLRP3 Inflammasome Is Involved in Tuberous Sclerosis Complex-Related Neuroinflammation.
Ding R, Zhang S, Meng L, Wang L, Han Z, Gui J, Yang J, Cheng L, Xie L, Jiang L
International journal of molecular sciences 2025 Jul 26;26(15)
International journal of molecular sciences 2025 Jul 26;26(15)
Impact of the PD-1/PD-L1 inhibitor SCL-1 on MDA-MB231 tumor growth in a humanized MHC-double knockout NOG mouse model.
Ikeya T, Ashizawa T, Kanematsu A, Maeda C, Iizuka A, Yamashita K, Miyata H, Kikuchi Y, Maruyama K, Ito M, Yamaguchi K, Akiyama Y
Scientific reports 2025 Jul 24;15(1):26918
Scientific reports 2025 Jul 24;15(1):26918
Characteristics of cancer mycobiome in patients with acral melanoma.
Huang R, Su X, Wang J, Sun Q, Kang D, Li L, Wu Y, Zhao L, Xie Z, Zou Z
Journal for immunotherapy of cancer 2025 Jul 15;13(7)
Journal for immunotherapy of cancer 2025 Jul 15;13(7)
Adventitial Injection of Hyaluronic Acid/Sodium Alginate Hydrogel Loaded With IL-33 Antibody Decreases Neointimal Hyperplasia.
Shi P, Sun P, Lou C, Fang J, Zhang L, Xie B, Zhang C
The Journal of surgical research 2025 Jan;305:107-117
The Journal of surgical research 2025 Jan;305:107-117
Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling.
Chen J, Sheng R, Mo Q, Backman LJ, Lu Z, Long Q, Chen Z, Cao Z, Zhang Y, Liu C, Zheng H, Qi Y, Cao M, Rui Y, Zhang W
Bioactive materials 2025 Feb;44:319-338
Bioactive materials 2025 Feb;44:319-338
Deubiquitinase JOSD2 alleviates colitis by inhibiting inflammation via deubiquitination of IMPDH2 in macrophages.
Liu X, Fang Y, Huang M, Tu S, Zheng B, Yuan H, Yu P, Lan M, Luo W, Zhou Y, Chen G, Shen Z, Wang Y, Liang G
Acta pharmaceutica Sinica. B 2025 Feb;15(2):1039-1055
Acta pharmaceutica Sinica. B 2025 Feb;15(2):1039-1055
The CC motif chemokine ligand 11 contributes to alcoholic liver disease.
Li J, Wang B, Wang S, Wang J, Zhou A, Gong S, Wang Y, Miao X, Guo Y, Wang H, Ge H
Life sciences 2025 Feb 15;363:123409
Life sciences 2025 Feb 15;363:123409
PANAXADIOL SAPONIN ALLEVIATES LPS-INDUCED CARDIOMYOPATHY SIMILAR TO DEXAMETHASONE VIA IMPROVING MITOCHONDRIAL QUALITY CONTROL.
Yang Z, Gao Y, Li D, Zhao L, Du Y
Shock (Augusta, Ga.) 2025 Feb 1;63(2):282-291
Shock (Augusta, Ga.) 2025 Feb 1;63(2):282-291
Farrerol confers neuroprotection in spinal cord injury by regulating macrophages/microglia polarization through the JAK2/STAT3 pathway.
Chen Y, Ren L, Xia J, Li B, Yang Y, Li J, Tao L, Song X, Lü H, Hu J
Experimental neurology 2025 Dec;394:115448
Experimental neurology 2025 Dec;394:115448
Macrophage-related immune responses to polyetherketoneketone bone implants: Single-cell transcriptome analysis.
Zhou J, Liang H, Chen J, Li A, Dai J, Li P
Materials today. Bio 2025 Dec;35:102257
Materials today. Bio 2025 Dec;35:102257
Synovium-On-A-Chip: Simulating the Microenvironment of the Rheumatoid Arthritis Synovium via Multicell Interactions to Target Fibroblast-Like Synoviocytes.
Diao W, Jiao Y, Deng T, Gu J, Wang B, Zhang Q, Wang P, Xu N, Xiao C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e11945
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e11945
IRF7 orchestrates proinflammatory macrophage polarization and joint destruction in rheumatoid arthritis.
Liu H, Wu C, Li G, Peng X, Zhang Z, Su Z, Lin J, Wang X, Shen H, Wu Y, Liu W, Wang P, Zheng G
Arthritis research & therapy 2025 Dec 8;28(1):10
Arthritis research & therapy 2025 Dec 8;28(1):10
Alpha-1 Antitrypsin Mediates Spontaneous Resolution of Acute Gouty Inflammation Via Inhibiting Caspase 3/GSDME-dependent Macrophage Pyroptosis.
Li X, Liu L, Tong S, Wang F, Zhu L, Cheng Q, Zhang P, Chen M, Xie Y, Wang L, Yu H, Wu H
Inflammation 2025 Dec 20;49(1):12
Inflammation 2025 Dec 20;49(1):12
Sappanone A Promotes Motor Function Recovery in Spinal Cord Injury Mice by Inhibiting Microglial M1 Polarization via Activation of the Keap1/Nrf2 Pathway.
Ren L, Chen Y, Xia J, Song X, Tao L, Li J, Xu L, Lü H, Hu J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71298
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71298
Cryopreservable, scalable and ready-to-use cell-laden patches for diabetic ulcer treatment.
Yu B, Peng L, Dang W, Fu Y, Li Z, Feng J, Zhao H, Wang T, Xu F, Yarmush ML, Huang H
Bioactive materials 2025 Aug;50:461-474
Bioactive materials 2025 Aug;50:461-474
C-Reactive Protein to Lymphocyte Ratio (CLR) and Lactate Dehydrogenase to Albumin Ratio (LAR) as Prognostic Biomarkers in Acral Melanoma: Association With Tertiary Lymphoid Structures and Immune Cell Infiltration.
Kang D, Su X, Wang J, Zhao L, Huang R, Zou Z
Cancer medicine 2025 Aug;14(15):e71078
Cancer medicine 2025 Aug;14(15):e71078
The foam cell-derived exosomes exacerbate ischemic white matter injury via transmitting metabolic defects to microglia.
Zhang H, Zhou LQ, Yang S, Dong MH, Chen L, Lu YL, Zhang LY, Zhang L, Chu YH, Xu LL, Pang XW, Zhu LF, Xu T, Yong TY, Wang W, Tian DS, Qin C
Cell metabolism 2025 Aug 5;37(8):1636-1654.e10
Cell metabolism 2025 Aug 5;37(8):1636-1654.e10
High ELK3 expression is associated with the wild type IDH1 in glioma and enhances infiltration of M2 macrophages.
Xin Z, Guo Y, Zhou Q, Wang L, Liu W, Jiang X, Ren C
International immunopharmacology 2025 Aug 28;161:115064
International immunopharmacology 2025 Aug 28;161:115064
Drp1 Promotes Macrophage M1 Polarization and Inflammatory Response in Autoimmune Myocarditis by Driving Mitochondrial Fission.
Lin L, Wei J, Xue J, Fan G, Zhu W, Zhu Y, Wu R
Journal of cardiovascular translational research 2025 Apr;18(2):237-246
Journal of cardiovascular translational research 2025 Apr;18(2):237-246
Localization of epidermal growth factor receptor-mutations using PNA:DNA probes in clinical specimens from patients with non-small cell lung cancer.
Miyata H, Shigeto H, Ikeya T, Ashizawa T, Iizuka A, Kikuchi Y, Maeda C, Kanematsu A, Yamashita K, Urakami K, Shimoda Y, Nagashima T, Ohshima K, Ohde Y, Isaka M, Sugino T, Muramatsu K, Kenmotsu H, Takahashi T, Yamaguchi K, Kitamatsu M, Yamamura S, Akiyama Y
Scientific reports 2025 Apr 2;15(1):11314
Scientific reports 2025 Apr 2;15(1):11314
Microneedle delivery of CAR-M-like engineered macrophages alleviates intervertebral disc degeneration through enhanced efferocytosis capacity.
Zhou X, Zhu D, Wu D, Li G, Liang H, Zhang W, Wu Y, Xu H, Zhang Z, Tong B, Song Y, Wang K, Feng X, Lei J, Wang H, Zhang X, Ma L, Chen Y, Wei J, Ou Z, Peng S, Wu X, Tan L, Wang B, Yang C
Cell reports. Medicine 2025 Apr 15;6(4):102079
Cell reports. Medicine 2025 Apr 15;6(4):102079
Analysis of clinical significance and molecular characteristics of methionine metabolism and macrophage-related patterns in hepatocellular carcinoma based on machine learning.
Wen D, Wang S, Yu J, Yu T, Liu Z, Li Y
Cancer biomarkers : section A of Disease markers 2024;39(1):37-48
Cancer biomarkers : section A of Disease markers 2024;39(1):37-48
Recruitment and polarization typing of tumor-associated macrophages is associated with tumor progression and poor prognosis in Wilms tumor patients.
Wang Z, Jin L, Wang J, Tian X, Mi T, Li M, Zhang Z, Wu X, Li M, Liu J, Wang Z, Liu Y, Luo J, Ren C, He D
PloS one 2024;19(11):e0309910
PloS one 2024;19(11):e0309910
Single-cell sequencing analysis reveals cancer-associated pericyte subgroup in esophageal squamous cell carcinoma to predict prognosis.
Xiong K, Pan B, Fang H, Tao Z
Frontiers in immunology 2024;15:1474673
Frontiers in immunology 2024;15:1474673
Identification of a distinct cluster of GDF15(high) macrophages induced by in vitro differentiation exhibiting anti-inflammatory activities.
Dai C, Zhang H, Zheng Z, Li CG, Ma M, Gao H, Zhang Q, Jiang F, Cui X
Frontiers in immunology 2024;15:1309739
Frontiers in immunology 2024;15:1309739
STAC3 as a poor prognostic biomarker in renal clear cell carcinoma: relationship with immune infiltration.
Zhang Y, Li J, Feng L, Cheng Y, Shi L, Yang Q, Wang Z, Yi X, Zhong G, Sun X, Cheng Z, Guo M
American journal of cancer research 2024;14(7):3294-3316
American journal of cancer research 2024;14(7):3294-3316
Tumor cell senescence-induced macrophage CD73 expression is a critical metabolic immune checkpoint in the aging tumor microenvironment.
Deng Y, Chen Q, Yang X, Sun Y, Zhang B, Wei W, Deng S, Meng J, Hu Y, Wang Y, Zhang Z, Wen L, Huang F, Wan C, Yang K
Theranostics 2024;14(3):1224-1240
Theranostics 2024;14(3):1224-1240
Intratumoral microbiota as a novel prognostic indicator in bladder cancer.
Zhang Y, Lin H, Liang L, Jin S, Lv J, Zhou Y, Xu F, Liu F, Feng N
Scientific reports 2024 Sep 27;14(1):22198
Scientific reports 2024 Sep 27;14(1):22198
Macrophage SHP2 Deficiency Alleviates Diabetic Nephropathy via Suppression of MAPK/NF-κB- Dependent Inflammation.
Han X, Wei J, Zheng R, Tu Y, Wang M, Chen L, Xu Z, Zheng L, Zheng C, Shi Q, Ying H, Liang G
Diabetes 2024 May 1;73(5):780-796
Diabetes 2024 May 1;73(5):780-796
Impact of intratumoral microbiome on tumor immunity and prognosis in human pancreatic ductal adenocarcinoma.
Abe S, Masuda A, Matsumoto T, Inoue J, Toyama H, Sakai A, Kobayashi T, Tanaka T, Tsujimae M, Yamakawa K, Gonda M, Masuda S, Uemura H, Kohashi S, Inomata N, Nagao K, Harada Y, Miki M, Irie Y, Juri N, Ko T, Yokotani Y, Oka Y, Ota S, Kanzawa M, Itoh T, Imai T, Fukumoto T, Hara E, Kodama Y
Journal of gastroenterology 2024 Mar;59(3):250-262
Journal of gastroenterology 2024 Mar;59(3):250-262
RSK4 promotes the macrophage recruitment and M2 polarization in esophageal squamous cell carcinoma.
He S, Lu M, Zhang L, Wang Z
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166996
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166996
Wireless Electric Cues Mediate Autologous DPSC-Loaded Conductive Hydrogel Microspheres to Engineer the Immuno-Angiogenic Niche for Homologous Maxillofacial Bone Regeneration.
Sun J, Xu C, Wo K, Wang Y, Zhang J, Lei H, Wang X, Shi Y, Fan W, Zhao B, Wang J, Su B, Yang C, Luo Z, Chen L
Advanced healthcare materials 2024 Mar;13(6):e2303405
Advanced healthcare materials 2024 Mar;13(6):e2303405
Increase in GPIHBP1 expression in advanced stage colorectal cancer indicates poor immune surveillance.
Gao M, Liao L, Lin Z, Hu X, Jia L, Gong W, Jia X
Translational cancer research 2024 Jun 30;13(6):2691-2703
Translational cancer research 2024 Jun 30;13(6):2691-2703
Dectin1 contributes to hypertensive vascular injury by promoting macrophage infiltration through activating the Syk/NF-κB pathway.
Zhang J, Tu Y, Wei J, Zheng R, Shao J, Chen Q, Liang G, Ying H, Han X, Shi Q
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166911
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166911
Biodegradable Cardiac Occluder with Surface Modification by Gelatin-Peptide Conjugate to Promote Endogenous Tissue Regeneration.
Kong P, Liu X, Li Z, Wang J, Gao R, Feng S, Li H, Zhang F, Feng Z, Huang P, Wang S, Zhuang D, Ouyang W, Wang W, Pan X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2305967
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(2):e2305967
Inhibition of heme oxygenase 1 alleviates thoracic aortic aneurysm via restoration of extracellular matrix.
Song W, Shen K, Fu G, Qin L, Bagaber G, Chen J, Wei L
Biochemical and biophysical research communications 2024 Jan 29;694:149405
Biochemical and biophysical research communications 2024 Jan 29;694:149405
VR23 and Bisdemethoxycurcumin Enhanced Nanofiber Niche with Durable Bidirectional Functions for Promoting Wound Repair and Inhibiting Scar Formation.
Xiang Y, Fan B, Shang P, Ding R, Du J, Zhu T, Zhang H, Yan X
Small methods 2024 Dec;8(12):e2400273
Small methods 2024 Dec;8(12):e2400273
LncRNA sequencing reveals an essential role for the lncRNA-mediated ceRNA network in penile squamous cell carcinoma.
Cao J, Du L, Zhao X, Liu Z, Yuan J, Luo Y, Zhang S, Qin Z, Guo J
Genes and immunity 2024 Dec;25(6):447-458
Genes and immunity 2024 Dec;25(6):447-458
Berberine modulates microglial polarization by activating TYROBP in Alzheimer's disease.
Yang Y, Wu J, Jia L, Feng S, Qi Z, Yu H, Wu Y, Wang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156237
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156237
A novel protein encoded by circLARP1B promotes the proliferation and migration of vascular smooth muscle cells by suppressing cAMP signaling.
Lu P, Fan J, Li B, Wang X, Song M
Atherosclerosis 2024 Aug;395:117575
Atherosclerosis 2024 Aug;395:117575
Mzb1 Attenuates Atherosclerotic Plaque Vulnerability in ApoE-/- Mice by Alleviating Apoptosis and Modulating Mitochondrial Function.
Zhu G, Li Y, Gao H, Li X, Fan H, Fan L
Journal of cardiovascular translational research 2024 Aug;17(4):782-794
Journal of cardiovascular translational research 2024 Aug;17(4):782-794
The influence of CLEC5A on early macrophage-mediated inflammation in COPD progression.
Li Q, Liu Y, Wang X, Xie C, Mei X, Cao W, Guan W, Lin X, Xie X, Zhou C, Yi E
Cellular and molecular life sciences : CMLS 2024 Aug 4;81(1):330
Cellular and molecular life sciences : CMLS 2024 Aug 4;81(1):330
Endothelial cell heterogeneity in colorectal cancer: tip cells drive angiogenesis.
Xie Z, Niu L, Du K, Chen L, Zheng G, Dai S, Dan H, Duan L, Dou X, Feng F, Zhang J, Zheng J
Cellular and molecular life sciences : CMLS 2024 Aug 22;81(1):365
Cellular and molecular life sciences : CMLS 2024 Aug 22;81(1):365
The relationship of ALPK1, hyaluronic acid and M1 macrophage polarization in the temporomandibular joint synovitis.
Zhao J, Feng Y, Liu X, Li H, Guo H, Ke J, Long X
Journal of cellular and molecular medicine 2024 Apr;28(7):e18172
Journal of cellular and molecular medicine 2024 Apr;28(7):e18172
Diaphorobacter nitroreducens synergize with oxaliplatin to reduce tumor burden in mice with lung adenocarcinoma.
Ni Y, Li R, Shen X, Yi D, Ren Y, Wang F, Geng Y, You Q
mSystems 2024 Apr 16;9(4):e0132323
mSystems 2024 Apr 16;9(4):e0132323
Hepatocellular carcinoma subtypes based on metabolic pathways reveals potential therapeutic targets.
He Z, Chen Q, He W, Cao J, Yao S, Huang Q, Zheng Y
Frontiers in oncology 2023;13:1086604
Frontiers in oncology 2023;13:1086604
A pan-cancer single-cell panorama of human natural killer cells.
Tang F, Li J, Qi L, Liu D, Bo Y, Qin S, Miao Y, Yu K, Hou W, Li J, Peng J, Tian Z, Zhu L, Peng H, Wang D, Zhang Z
Cell 2023 Sep 14;186(19):4235-4251.e20
Cell 2023 Sep 14;186(19):4235-4251.e20
Low-dose adropin stimulates inflammasome activation of macrophage via mitochondrial ROS involved in colorectal cancer progression.
Jia L, Liao L, Jiang Y, Hu X, Lu G, Xiao W, Gong W, Jia X
BMC cancer 2023 Oct 30;23(1):1042
BMC cancer 2023 Oct 30;23(1):1042
Localized delivery of anti-inflammatory agents using extracellular matrix-nanostructured lipid carriers hydrogel promotes cardiac repair post-myocardial infarction.
Wang X, Shi H, Huang S, Zhang Y, He X, Long Q, Qian B, Zhong Y, Qi Z, Zhao Q, Ye X
Biomaterials 2023 Nov;302:122364
Biomaterials 2023 Nov;302:122364
Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages.
Lu Y, Zhang H, Pan H, Zhang Z, Zeng H, Xie H, Yin J, Tang W, Lin R, Zeng C, Cai D
Journal of translational medicine 2023 May 22;21(1):339
Journal of translational medicine 2023 May 22;21(1):339
Tanshinone IIA enhances the therapeutic efficacy of mesenchymal stem cells derived exosomes in myocardial ischemia/reperfusion injury via up-regulating miR-223-5p.
Li S, Yang K, Cao W, Guo R, Liu Z, Zhang J, Fan A, Huang Y, Ma C, Li L, Fan G
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:13-26
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:13-26
ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression.
Zhang Y, Wang W, Min J, Liu S, Wang Q, Wang Y, Xiao Y, Li X, Zhou Z, Liu S
Cell reports 2023 Jun 27;42(6):112654
Cell reports 2023 Jun 27;42(6):112654
An N6-methyladenosine regulation- and mRNAsi-related prognostic index reveals the distinct immune microenvironment and immunotherapy responses in lower-grade glioma.
Tang G, Peng J, Huo L, Yin W
BMC bioinformatics 2023 Jun 1;24(1):225
BMC bioinformatics 2023 Jun 1;24(1):225
Aprepitant inhibits the progression of esophageal squamous cancer by blocking the truncated neurokinin‑1 receptor.
Zheng Y, Sang M, Liu F, Gu L, Li J, Wu Y, Shan B
Oncology reports 2023 Jul;50(1)
Oncology reports 2023 Jul;50(1)
Methylene blue targets PHD3 expression in murine microglia to mitigate lipopolysaccharide-induced neuroinflammation and neurocognitive impairments.
Ou G, Che J, Dong J, Deng Y, Jiang X, Sun Y, He Z, Chen W, Zhang J
International immunopharmacology 2023 Jul;120:110349
International immunopharmacology 2023 Jul;120:110349
Macrophages and derived-TNF-α promote lipopolysaccharide-induced upregulation of endogenous β-glucuronidase in the epithelial cells of the bile duct: A possible facilitator of hepatolithiasis formation.
Yang Y, Wang Y, Wang C, Wu S, Yao D
Clinics and research in hepatology and gastroenterology 2023 Jan;47(1):102062
Clinics and research in hepatology and gastroenterology 2023 Jan;47(1):102062
Parasympathetic-macrophages-ductal epithelial cells axis promotes female rat submandibular gland regeneration after excretory duct ligation/deligation.
Wang B, Li D, Li J, An W, Li Z, Shao Q, Qin L
Archives of oral biology 2023 Jan;145:105586
Archives of oral biology 2023 Jan;145:105586
GSDME-mediated pyroptosis promotes the progression and associated inflammation of atherosclerosis.
Wei Y, Lan B, Zheng T, Yang L, Zhang X, Cheng L, Tuerhongjiang G, Yuan Z, Wu Y
Nature communications 2023 Feb 18;14(1):929
Nature communications 2023 Feb 18;14(1):929
ASGR1 promotes liver injury in sepsis by modulating monocyte-to-macrophage differentiation via NF-κB/ATF5 pathway.
Shi R, Wang J, Zhang Z, Leng Y, Chen AF
Life sciences 2023 Feb 15;315:121339
Life sciences 2023 Feb 15;315:121339
UBC9 deficiency enhances immunostimulatory macrophage activation and subsequent antitumor T cell response in prostate cancer.
Xiao J, Sun F, Wang YN, Liu B, Zhou P, Wang FX, Zhou HF, Ge Y, Yue TT, Luo JH, Yang CL, Rong SJ, Xiong ZZ, Ma S, Zhang Q, Xun Y, Yang CG, Luan Y, Wang SG, Wang CY, Wang ZH
The Journal of clinical investigation 2023 Feb 15;133(4)
The Journal of clinical investigation 2023 Feb 15;133(4)
Single-cell multi-omics analysis of human testicular germ cell tumor reveals its molecular features and microenvironment.
Lu X, Luo Y, Nie X, Zhang B, Wang X, Li R, Liu G, Zhou Q, Liu Z, Fan L, Hotaling JM, Zhang Z, Bo H, Guo J
Nature communications 2023 Dec 20;14(1):8462
Nature communications 2023 Dec 20;14(1):8462
Purinergic receptor P2X7 contributes to abdominal aortic aneurysm development via modulating macrophage pyroptosis and inflammation.
Sun L, Li X, Luo Z, Li M, Liu H, Zhu Z, Wang J, Lu P, Wang L, Yang C, Wang T, He H, Li M, Shu C, Li J
Translational research : the journal of laboratory and clinical medicine 2023 Aug;258:72-85
Translational research : the journal of laboratory and clinical medicine 2023 Aug;258:72-85
Inhibition of IL-4/STAT6/IRF4 signaling reduces the epithelial-mesenchymal transition in eosinophilic chronic rhinosinusitis with nasal polyps.
Chen J, Chen S, Gong G, Yang F, Chen J, Wang Y
International immunopharmacology 2023 Aug;121:110554
International immunopharmacology 2023 Aug;121:110554
Single-cell and spatial analyses reveal the association between gene expression of glutamine synthetase with the immunosuppressive phenotype of APOE+CTSZ+TAM in cancers.
Wei J, Yu W, Chen J, Huang G, Zhang L, Chen Z, Hu M, Gong X, Du H
Molecular oncology 2023 Apr;17(4):611-628
Molecular oncology 2023 Apr;17(4):611-628
Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.
Feng C, Shan M, Xia Y, Zheng Z, He K, Wei Y, Song K, Meng T, Liu H, Hao Y, Liang Z, Wang Y, Huang Y
Frontiers in immunology 2022;13:940645
Frontiers in immunology 2022;13:940645
YTHDF1 Negatively Regulates Treponema pallidum-Induced Inflammation in THP-1 Macrophages by Promoting SOCS3 Translation in an m6A-Dependent Manner.
Li Z, Teng M, Jiang Y, Zhang L, Luo X, Liao Y, Yang B
Frontiers in immunology 2022;13:857727
Frontiers in immunology 2022;13:857727
Single-cell RNA sequencing reveals TCR(+) macrophages in HPV-related head and neck squamous cell carcinoma.
Jiang Y, Zhang S, Tang L, Li R, Zhai J, Luo S, Peng Y, Chen X, Wei L
Frontiers in immunology 2022;13:1030222
Frontiers in immunology 2022;13:1030222
Heparin binding epidermal growth factor-like growth factor is a prognostic marker correlated with levels of macrophages infiltrated in lung adenocarcinoma.
Van Hiep N, Sun WL, Feng PH, Lin CW, Chen KY, Luo CS, Dung LN, Van Quyet H, Wu SM, Lee KY
Frontiers in oncology 2022;12:963896
Frontiers in oncology 2022;12:963896
ICOS-Positive Regulatory T Cells in Hepatocellular Carcinoma: The Perspective from Digital Pathology Analysis.
Lu LC, Deantonio C, Palu CC, Lee YH, Mitchell LS, Cowan M, Corser M, Sherry L, Cheng AL, Quaratino S, Shao YY, Sainson RCA, Hsu CH
Oncology 2022;100(8):419-428
Oncology 2022;100(8):419-428
Identifying potential signatures for atherosclerosis in the context of predictive, preventive, and personalized medicine using integrative bioinformatics approaches and machine-learning strategies.
Xu J, Zhou H, Cheng Y, Xiang G
The EPMA journal 2022 Sep;13(3):433-449
The EPMA journal 2022 Sep;13(3):433-449
An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation.
Ferretti G, Romano A, Sirabella R, Serafini S, Maier TJ, Matrone C
Cell & bioscience 2022 Nov 8;12(1):182
Cell & bioscience 2022 Nov 8;12(1):182
Blockade of Kv1.3 Potassium Channel Inhibits Microglia-Mediated Neuroinflammation in Epilepsy.
Zhang X, Liang P, Zhang Y, Wu Y, Song Y, Wang X, Chen T, Peng B, Liu W, Yin J, Han S, He X
International journal of molecular sciences 2022 Nov 24;23(23)
International journal of molecular sciences 2022 Nov 24;23(23)
The Immunological Contribution of a Novel Metabolism-Related Signature to the Prognosis and Anti-Tumor Immunity in Cervical Cancer.
Yu S, Li X, Ma M, Yang R, Zhang J, Wu S
Cancers 2022 May 13;14(10)
Cancers 2022 May 13;14(10)
Increased co-expression of MEST and BRCA1 is associated with worse prognosis and immune infiltration in ovarian cancer.
Zhang J, Yu S, Li Q, Wang Q, Zhang J
Gynecologic oncology 2022 Mar;164(3):566-576
Gynecologic oncology 2022 Mar;164(3):566-576
Construction and analysis of a ceRNA network and patterns of immune infiltration in chronic rhinosinusitis with nasal polyps: based on data mining and experimental verification.
Chen JC, Xing QL, Yang HW, Yang F, Luo Y, Kong WJ, Wang YJ
Scientific reports 2022 Jun 13;12(1):9735
Scientific reports 2022 Jun 13;12(1):9735
Multifunctional chitin-based hollow nerve conduit for peripheral nerve regeneration and neuroma inhibition.
Yang X, Huang L, Yi X, Huang S, Duan B, Yu A
Carbohydrate polymers 2022 Aug 1;289:119443
Carbohydrate polymers 2022 Aug 1;289:119443
SIGLEC15 amplifies immunosuppressive properties of tumor-associated macrophages in pancreatic cancer.
Li TJ, Jin KZ, Li H, Ye LY, Li PC, Jiang B, Lin X, Liao ZY, Zhang HR, Shi SM, Lin MX, Fei QL, Xiao ZW, Xu HX, Liu L, Yu XJ, Wu WD
Cancer letters 2022 Apr 1;530:142-155
Cancer letters 2022 Apr 1;530:142-155
Ligustrazine Alleviate Acute Lung Injury Through Suppressing Pyroptosis and Apoptosis of Alveolar Macrophages.
Jiang R, Xu J, Zhang Y, Zhu X, Liu J, Tan Y
Frontiers in pharmacology 2021;12:680512
Frontiers in pharmacology 2021;12:680512
Novel roles of VAT1 expression in the immunosuppressive action of diffuse gliomas.
Yang P, Wang K, Zhang C, Wang Z, Liu Q, Wang J, Jiang T, Shan X
Cancer immunology, immunotherapy : CII 2021 Sep;70(9):2589-2600
Cancer immunology, immunotherapy : CII 2021 Sep;70(9):2589-2600
PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice.
Xiong R, Jiang W, Li N, Liu B, He R, Wang B, Geng Q
Ecotoxicology and environmental safety 2021 Sep 15;221:112433
Ecotoxicology and environmental safety 2021 Sep 15;221:112433
Redox-sensitive activation of CCL7 by BRG1 in hepatocytes during liver injury.
Kong M, Dong W, Zhu Y, Fan Z, Miao X, Guo Y, Li C, Duan Y, Lu Y, Li Z, Xu Y
Redox biology 2021 Oct;46:102079
Redox biology 2021 Oct;46:102079
The Protective Role of Yin-Yang 1 in Cardiac Injury and Remodeling After Myocardial Infarction.
Huang Y, Li L, Chen H, Liao Q, Yang X, Yang D, Xia X, Wang H, Wang WE, Chen L, Zeng C
Journal of the American Heart Association 2021 Nov 2;10(21):e021895
Journal of the American Heart Association 2021 Nov 2;10(21):e021895
Berberine exerts anti-tumor activity in diffuse large B-cell lymphoma by modulating c-myc/CD47 axis.
Ren S, Cai Y, Hu S, Liu J, Zhao Y, Ding M, Chen X, Zhan L, Zhou X, Wang X
Biochemical pharmacology 2021 Jun;188:114576
Biochemical pharmacology 2021 Jun;188:114576
The downregulation of NCXs is positively correlated with the prognosis of stage II-IV colon cancer.
Xia Z, Wang C, Zhang H
World journal of surgical oncology 2021 Jun 14;19(1):177
World journal of surgical oncology 2021 Jun 14;19(1):177
Lung Myofibroblasts Promote Macrophage Profibrotic Activity through Lactate-induced Histone Lactylation.
Cui H, Xie N, Banerjee S, Ge J, Jiang D, Dey T, Matthews QL, Liu RM, Liu G
American journal of respiratory cell and molecular biology 2021 Jan;64(1):115-125
American journal of respiratory cell and molecular biology 2021 Jan;64(1):115-125
Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy.
Han X, Xu T, Fang Q, Zhang H, Yue L, Hu G, Sun L
Redox biology 2021 Aug;44:102010
Redox biology 2021 Aug;44:102010
Saikosaponin-d attenuated lipopolysaccharide-induced depressive-like behaviors via inhibiting microglia activation and neuroinflammation.
Su J, Pan YW, Wang SQ, Li XZ, Huang F, Ma SP
International immunopharmacology 2020 Mar;80:106181
International immunopharmacology 2020 Mar;80:106181
Noncoding RNA 886 alleviates tumor cellular immunological rejection in host C57BL/C mice.
Ma H, Wang M, Zhou Y, Yang JJ, Wang LY, Yang RH, Wen MJ, Kong L
Cancer medicine 2020 Jul;9(14):5258-5271
Cancer medicine 2020 Jul;9(14):5258-5271
Tumor-associated macrophages (TAMs) depend on Shp2 for their anti-tumor roles in colorectal cancer.
Wang S, Yao Y, Li H, Zheng G, Lu S, Chen W
American journal of cancer research 2019;9(9):1957-1969
American journal of cancer research 2019;9(9):1957-1969
Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression.
Liu N, Luo J, Kuang D, Xu S, Duan Y, Xia Y, Wei Z, Xie X, Yin B, Chen F, Luo S, Liu H, Wang J, Jiang K, Gong F, Tang ZH, Cheng X, Li H, Li Z, Laurence A, Wang G, Yang XP
The Journal of clinical investigation 2019 Feb 1;129(2):631-646
The Journal of clinical investigation 2019 Feb 1;129(2):631-646
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