DMABT-46628MR

antibody from Creative Diagnostics

Targeting: CD68 DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

DMABT-46628MR

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DMABT-46628MR, RRID:AB_2394217

Product name

Anti-CD68 monoclonal antibody, clone FE2

Antibody type

Monoclonal

Description

CD68 is a 110 kDa highly glycosylated lysosomal membrane protein. The CD68 protein belongs to a family of lysosomal glycoproteins/plasma membrane shuttling proteins that play a role in endocytosis and/or lysosomal trafficking. Unlike many other CD leucocyte antigens, the CD68 molecule is antigenically very heterogeneous, and different antibodies to CD68 show different cellular reactivities.CD68 is expressed strongly in cytoplasmic granules, and weakly on the surface of macrophages, monocytes, neutrophils, basophils and NK-cells. CD68 is also found in neoplastic cells of myeloid background. Additionally, CD68 is expressed by approximately 40% of peripheral blood Bcells and is weakly expressed in 50% of B cell type acute lymphoblastic leukaemia cells. CD68 can also be found in the cytoplasm of non-haematopoietic tissues, especially the liver, glomeruli and renal tubules.

Reactivity

Rat, Bovine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

FE2

Vial size

100 _g

Concentration

IgG concentration 0.5 mg/ml

Storage

Store at +4 oC or at -20 oC if preferred.This product should be stored undiluted.Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.