10-4171-25

antibody from ABEOMICS Inc.
Targeting: CD68 DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1
Provider product page for 10-4171-25

Antibody data

Product number
10-4171-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-CD68 Antibody
Antibody type
Monoclonal
Description
CD68 is a transmembrane glycoprotein which acts as a commercialized marker for human monocytes and macrophages. Its expression is thought to be regulated by a macrophage-specific promoter. However, several immunohistochemical studies have indicated that CD68 antibodies also react with other haematopoietic and non-haematopoietic cell types. It also can stain myeloid cells, dendritic cells, fibroblasts, Langerhans cells and others. In human monocytes, which produce high levels of CD68 mRNA, the gene is characterized by intramolecular ligations between the promoter and the 3' intervening region. CD68 is also used as a pan-macrophage marker for TAM (Tumor-Associated Macrophages) which always involve in carcinogenesis. 
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
A partial length recombinant protei
n (a.a 80-280) of CD68 was used as
the immunogen for this antibody.
Isotype
IgG
Antibody clone number
ABM53F5
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
CD68 protein structure - 10-4171-25 shown in red.