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antibody from Atlas Antibodies
Targeting: CD68
DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- HPA048982 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA048982, RRID:AB_2680587
- Product name
- Anti-CD68
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human CD68, Gene description: CD68 molecule, Alternative Gene Names: DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1, Validated applications: WB, IHC, Uniprot ID: P34810, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Human Stem Cell–Derived Cardiomyocytes Integrate Into the Heart of Monkeys With Right Ventricular Pressure Overload
Patient-derived tumor organoids mimic treatment-induced DNA damage response in glioblastoma.
Human galectin-9 promotes the expansion of HIV reservoirs in vivo in humanized mice
Macrophage and neutrophil heterogeneity at single-cell spatial resolution in human inflammatory bowel disease
Tenascin-C can Serve as an Indicator for the Immunosuppressive Microenvironment of Diffuse Low-Grade Gliomas
LRIG2 promotes glioblastoma progression by modulating innate antitumor immunity through macrophage infiltration and polarization
Activated microglia do not increase 18 kDa translocator protein (TSPO) expression in the multiple sclerosis brain
Kinomics platform using GBM tissue identifies BTK as being associated with higher patient survival
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies
Reduced Protumorigenic Tumor-Associated Macrophages With Statin Use in Premalignant Human Lung Adenocarcinoma
3-Bromopyruvate alleviates the development of monocrotaline-induced rat pulmonary arterial hypertension by decreasing aerobic glycolysis, inducing apoptosis, and suppressing inflammation
Macrophage Subpopulations and the Acute Inflammatory Response of Elderly Human Skeletal Muscle to Physiological Resistance Exercise
Food hypersensitivity-induced chronic gastrointestinal inflammation in a non-human primate model of diet-induced obesity.
Inflammasome-Driven Interleukin-1α and Interleukin-1β Production in Atherosclerotic Plaques Relates to Hyperlipidemia and Plaque Complexity.
The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity
Structural and functional features of central nervous system lymphatic vessels
Structural and functional features of central nervous system lymphatic vessels
Scholz J, Secreto F, Wobig J, Kurian J, Hagen C, Zinnen A, Vu D, Johnson S, Cetta F, Qureshi Y, Reams R, Cannon B, Heyer C, Chang M, Fadra N, Coonen J, Simmons H, Mejia A, Hayes J, Basu P, Capuano S, Bondarenko V, Metzger J, Nelson T, Emborg M
Cell Transplantation 2024;33
Cell Transplantation 2024;33
Patient-derived tumor organoids mimic treatment-induced DNA damage response in glioblastoma.
Majc B, Habič A, Malavolta M, Vittori M, Porčnik A, Bošnjak R, Mlakar J, Matjašič A, Zupan A, Vidmar MS, Turnšek TL, Sadikov A, Breznik B, Novak M
iScience 2024 Sep 20;27(9):110604
iScience 2024 Sep 20;27(9):110604
Human galectin-9 promotes the expansion of HIV reservoirs in vivo in humanized mice
Yuan Z, Giron L, Hart C, Gyampoh A, Koshy J, Hong K, Niki T, Premeaux T, Ndhlovu L, Deleage C, Montaner L, Abdel-Mohsen M
AIDS 2023;37(4):571-577
AIDS 2023;37(4):571-577
Macrophage and neutrophil heterogeneity at single-cell spatial resolution in human inflammatory bowel disease
Garrido-Trigo A, Corraliza A, Veny M, Dotti I, Melón-Ardanaz E, Rill A, Crowell H, Corbí Á, Gudiño V, Esteller M, Álvarez-Teubel I, Aguilar D, Masamunt M, Killingbeck E, Kim Y, Leon M, Visvanathan S, Marchese D, Caratù G, Martin-Cardona A, Esteve M, Ordás I, Panés J, Ricart E, Mereu E, Heyn H, Salas A
Nature Communications 2023;14(1)
Nature Communications 2023;14(1)
Tenascin-C can Serve as an Indicator for the Immunosuppressive Microenvironment of Diffuse Low-Grade Gliomas
Zhang P, Liu G, Hu J, Chen S, Wang B, Peng P, Yu X, Guo D
Frontiers in Immunology 2022;13
Frontiers in Immunology 2022;13
LRIG2 promotes glioblastoma progression by modulating innate antitumor immunity through macrophage infiltration and polarization
Hu J, Dong F, He Y, Xia X, Cheng F, Chen S, Hou X, Zhang P, Liu G, Li Y, Gao Q, Dong M, Li T, Li W, Xiao Q, Li X, Yu X, Xi G, Guo D, Wu X, Wang B
Journal for ImmunoTherapy of Cancer 2022;10(9):e004452
Journal for ImmunoTherapy of Cancer 2022;10(9):e004452
Activated microglia do not increase 18 kDa translocator protein (TSPO) expression in the multiple sclerosis brain
Nutma E, Gebro E, Marzin M, van der Valk P, Matthews P, Owen D, Amor S
Glia 2021;69(10):2447-2458
Glia 2021;69(10):2447-2458
Kinomics platform using GBM tissue identifies BTK as being associated with higher patient survival
Al Shboul S, Curran O, Alfaro J, Lickiss F, Nita E, Kowalski J, Naji F, Nenutil R, Ball K, Krejcir R, Vojtesek B, Hupp T, Brennan P
Life Science Alliance 2021;4(12):e202101054
Life Science Alliance 2021;4(12):e202101054
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies
Li D, Edwards R, Manne K, Martinez D, Schäfer A, Alam S, Wiehe K, Lu X, Parks R, Sutherland L, Oguin T, McDanal C, Perez L, Mansouri K, Gobeil S, Janowska K, Stalls V, Kopp M, Cai F, Lee E, Foulger A, Hernandez G, Sanzone A, Tilahun K, Jiang C, Tse L, Bock K, Minai M, Nagata B, Cronin K, Gee-Lai V, Deyton M, Barr M, Von Holle T, Macintyre A, Stover E, Feldman J, Hauser B, Caradonna T, Scobey T, Rountree W, Wang Y, Moody M, Cain D, DeMarco C, Denny T, Woods C, Petzold E, Schmidt A, Teng I, Zhou T, Kwong P, Mascola J, Graham B, Moore I, Seder R, Andersen H, Lewis M, Montefiori D, Sempowski G, Baric R, Acharya P, Haynes B, Saunders K
Cell 2021;184(16):4203-4219.e32
Cell 2021;184(16):4203-4219.e32
Reduced Protumorigenic Tumor-Associated Macrophages With Statin Use in Premalignant Human Lung Adenocarcinoma
Le Quesne J, Pritchard C, Officer L, Kamata T, Smith C, Sereno M, Das M, Baena J, Al Dujaily E
JNCI Cancer Spectrum 2020;4(2)
JNCI Cancer Spectrum 2020;4(2)
3-Bromopyruvate alleviates the development of monocrotaline-induced rat pulmonary arterial hypertension by decreasing aerobic glycolysis, inducing apoptosis, and suppressing inflammation
Liu J, Wang W, Wang L, Qi X, Sha Y, Yang T
Chinese Medical Journal 2020;133(1):49-60
Chinese Medical Journal 2020;133(1):49-60
Macrophage Subpopulations and the Acute Inflammatory Response of Elderly Human Skeletal Muscle to Physiological Resistance Exercise
Jensen S, Bechshøft C, Heisterberg M, Schjerling P, Andersen J, Kjaer M, Mackey A
Frontiers in Physiology 2020;11
Frontiers in Physiology 2020;11
Food hypersensitivity-induced chronic gastrointestinal inflammation in a non-human primate model of diet-induced obesity.
Mustafa T, Li Q, Kelly LE, Gibbon A, Ryan I, Roffey K, Simonds S, Cowley MA, Sleeman MW
PloS one 2019;14(4):e0214621
PloS one 2019;14(4):e0214621
Inflammasome-Driven Interleukin-1α and Interleukin-1β Production in Atherosclerotic Plaques Relates to Hyperlipidemia and Plaque Complexity.
Jiang X, Wang F, Wang Y, Gisterå A, Roy J, Paulsson-Berne G, Hedin U, Lerman A, Hansson GK, Herrmann J, Yan ZQ
JACC. Basic to translational science 2019 Jun;4(3):304-317
JACC. Basic to translational science 2019 Jun;4(3):304-317
The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity
Swystun L, Lai J, Notley C, Georgescu I, Paine A, Mewburn J, Nesbitt K, Schledzewski K, Géraud C, Kzhyshkowska J, Goerdt S, Hopman W, Montgomery R, James P, Lillicrap D
Journal of Clinical Investigation 2018;128(9):4057-4073
Journal of Clinical Investigation 2018;128(9):4057-4073
Structural and functional features of central nervous system lymphatic vessels
Louveau A, Smirnov I, Keyes T, Eccles J, Rouhani S, Peske J, Derecki N, Castle D, Mandell J, Lee K, Harris T, Kipnis J
Nature 2015;523(7560):337-341
Nature 2015;523(7560):337-341
Structural and functional features of central nervous system lymphatic vessels
Louveau A, Smirnov I, Keyes T, Eccles J, Rouhani S, Peske J, Derecki N, Castle D, Mandell J, Lee K, Harris T, Kipnis J
Nature 2015 June;523(7560):337-341
Nature 2015 June;523(7560):337-341
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in U-87MG ATCC cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-CD68 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human tonsil and skeletal muscle tissues using HPA048982 antibody. Corresponding CD68 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
