MAB20401
antibody from R&D Systems
Targeting: CD68
DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1
Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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Validation data
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- Product number
- MAB20401 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CD68/SR-D1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human CD68/SR-D1 in direct ELISAs.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
AAB25811
- Isotype
- IgG
- Antibody clone number
- 298807
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Autophagy Is an Innate Mechanism Associated with Leprosy Polarization.
Association between PON1 rs662 polymorphism and coronary artery disease.
Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema.
Knockdown of Stat3 activity in vivo prevents diabetic glomerulopathy.
Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity.
Human periprosthetic tissues implanted in severe combined immunodeficient mice respond to gene transfer of a cytokine inhibitor.
Silva BJ, Barbosa MG, Andrade PR, Ferreira H, Nery JA, CĂ´rte-Real S, da Silva GM, Rosa PS, Fabri M, Sarno EN, Pinheiro RO
PLoS pathogens 2017 Jan;13(1):e1006103
PLoS pathogens 2017 Jan;13(1):e1006103
Association between PON1 rs662 polymorphism and coronary artery disease.
Liu T, Zhang X, Zhang J, Liang Z, Cai W, Huang M, Yan C, Zhu Z, Han Y
European journal of clinical nutrition 2014 Sep;68(9):1029-35
European journal of clinical nutrition 2014 Sep;68(9):1029-35
Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema.
Shan M, Cheng HF, Song LZ, Roberts L, Green L, Hacken-Bitar J, Huh J, Bakaeen F, Coxson HO, Storness-Bliss C, Ramchandani M, Lee SH, Corry DB, Kheradmand F
Science translational medicine 2009 Oct 28;1(4):4ra10
Science translational medicine 2009 Oct 28;1(4):4ra10
Knockdown of Stat3 activity in vivo prevents diabetic glomerulopathy.
Lu TC, Wang ZH, Feng X, Chuang PY, Fang W, Shen Y, Levy DE, Xiong H, Chen N, He JC
Kidney international 2009 Jul;76(1):63-71
Kidney international 2009 Jul;76(1):63-71
Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity.
Lumeng CN, Deyoung SM, Bodzin JL, Saltiel AR
Diabetes 2007 Jan;56(1):16-23
Diabetes 2007 Jan;56(1):16-23
Human periprosthetic tissues implanted in severe combined immunodeficient mice respond to gene transfer of a cytokine inhibitor.
Yang SY, Nasser S, Markel DC, Robbins PD, Wooley PH
The Journal of bone and joint surgery. American volume 2005 May;87(5):1088-97
The Journal of bone and joint surgery. American volume 2005 May;87(5):1088-97
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- CD68/SR-D1 in Human PBMCs. CD68/SR-D1 was detected in immersion fixed human peripheral blood mononuclear cells (PBMCs) stimulated with PHA using Human CD68/SR-D1 Monoclonal Antibody (Catalog # MAB20401) at 25 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). Specific staining was localized to the plasma membrane and cytoplasm. View our protocol for Fluorescent ICC Staining of Non-adherent Cells.