ZBED1

This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. It was earlier identified as a gene with similarity to Ac transposable elements, however, was found not to have transposase activity. Later studies show that this gene product is localized in the nucleus and functions as a transcription factor. It binds to DNA elements found in the promoter regions of several genes related to cell proliferation, such as histone H1, hence may have a role in regulating genes related to cell proliferation. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. [provided by RefSeq, Jan 2010]

Description

Zinc finger BED-type containing 1

Tissue specificity

Tissue enhanced (skeletal muscle)

Subcell location

Nucleoplasm, Nuclear membrane, Centrosome

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transcription factors

Chromosome

X:p22.33 (2486414 - 2500976)

Ensembl ID

ENSG00000214717  (ver. 103.38)

Orthologs

-

UniProt

O96006

neXtProt

NX_O96006

Human splice variants