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- References [10]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 13759-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13759-1-AP, RRID:AB_2156286
- Product name
- P4HA2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated P4HA2 antibody (Cat. #13759-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references P4HA2 contributes to cervical cancer progression via inducing epithelial-mesenchymal transition.
Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis.
Epigenetic SMAD3 Repression in Tumor-Associated Fibroblasts Impairs Fibrosis and Response to the Antifibrotic Drug Nintedanib in Lung Squamous Cell Carcinoma.
Collagen prolyl 4-hydroxylase 2 predicts worse prognosis and promotes glycolysis in cervical cancer.
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Prolyl 4-hydroxylase 2 promotes B-cell lymphoma progression via hydroxylation of Carabin.
Nintedanib selectively inhibits the activation and tumour-promoting effects of fibroblasts from lung adenocarcinoma patients.
Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.
Hepatitis B virus X protein promotes the development of liver fibrosis and hepatoma through downregulation of miR-30e targeting P4HA2 mRNA.
Identification of PRDX4 and P4HA2 as metastasis-associated proteins in oral cavity squamous cell carcinoma by comparative tissue proteomics of microdissected specimens using iTRAQ technology.
Cao Y, Han Q, Li J, Jia Y, Zhang R, Shi H
Journal of Cancer 2020;11(10):2788-2799
Journal of Cancer 2020;11(10):2788-2799
Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis.
Marie KL, Sassano A, Yang HH, Michalowski AM, Michael HT, Guo T, Tsai YC, Weissman AM, Lee MP, Jenkins LM, Zaidi MR, Pérez-Guijarro E, Day CP, Ylaya K, Hewitt SM, Patel NL, Arnheiter H, Davis S, Meltzer PS, Merlino G, Mishra PJ
Nature communications 2020 Jan 16;11(1):333
Nature communications 2020 Jan 16;11(1):333
Epigenetic SMAD3 Repression in Tumor-Associated Fibroblasts Impairs Fibrosis and Response to the Antifibrotic Drug Nintedanib in Lung Squamous Cell Carcinoma.
Ikemori R, Gabasa M, Duch P, Vizoso M, Bragado P, Arshakyan M, Luis IC, Marín A, Morán S, Castro M, Fuster G, Gea-Sorli S, Jauset T, Soucek L, Montuenga LM, Esteller M, Monsó E, Peinado VI, Gascon P, Fillat C, Hilberg F, Reguart N, Alcaraz J
Cancer research 2020 Jan 15;80(2):276-290
Cancer research 2020 Jan 15;80(2):276-290
Collagen prolyl 4-hydroxylase 2 predicts worse prognosis and promotes glycolysis in cervical cancer.
Li Q, Wang Q, Zhang Q, Zhang J, Zhang J
American journal of translational research 2019;11(11):6938-6951
American journal of translational research 2019;11(11):6938-6951
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Wang T, Fu X, Jin T, Zhang L, Liu B, Wu Y, Xu F, Wang X, Ye K, Zhang W, Ye L
EBioMedicine 2019 Jul;45:168-180
EBioMedicine 2019 Jul;45:168-180
Prolyl 4-hydroxylase 2 promotes B-cell lymphoma progression via hydroxylation of Carabin.
Jiang W, Zhou X, Li Z, Liu K, Wang W, Tan R, Cong X, Shan J, Zhan Y, Cui Z, Jiang L, Li Q, Shen S, Bai M, Cheng Y, Li B, Tan M, Ma DK, Liu JO, Dang Y
Blood 2018 Mar 22;131(12):1325-1336
Blood 2018 Mar 22;131(12):1325-1336
Nintedanib selectively inhibits the activation and tumour-promoting effects of fibroblasts from lung adenocarcinoma patients.
Gabasa M, Ikemori R, Hilberg F, Reguart N, Alcaraz J
British journal of cancer 2017 Oct 10;117(8):1128-1138
British journal of cancer 2017 Oct 10;117(8):1128-1138
Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.
Cowling RT, Park JI, Sotimehin AE, Greenberg BH
Journal of molecular and cellular cardiology 2017 Dec;113:1-8
Journal of molecular and cellular cardiology 2017 Dec;113:1-8
Hepatitis B virus X protein promotes the development of liver fibrosis and hepatoma through downregulation of miR-30e targeting P4HA2 mRNA.
Feng GX, Li J, Yang Z, Zhang SQ, Liu YX, Zhang WY, Ye LH, Zhang XD
Oncogene 2017 Dec 14;36(50):6895-6905
Oncogene 2017 Dec 14;36(50):6895-6905
Identification of PRDX4 and P4HA2 as metastasis-associated proteins in oral cavity squamous cell carcinoma by comparative tissue proteomics of microdissected specimens using iTRAQ technology.
Chang KP, Yu JS, Chien KY, Lee CW, Liang Y, Liao CT, Yen TC, Lee LY, Huang LL, Liu SC, Chang YS, Chi LM
Journal of proteome research 2011 Nov 4;10(11):4935-47
Journal of proteome research 2011 Nov 4;10(11):4935-47
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 13759-1-AP(P4HA2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The P4HA2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human P4HA2. This antibody recognizes human,mouse,rat antigen. The P4HA2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 13759-1-AP(P4HA2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
