Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
Reference
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- Product number
- 21777-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- TTF1; NKX2-1 antibody
- Antibody type
- Polyclonal
- Description
- TTF1; NKX2-1 antibody (Cat. #21777-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Prenatal amoxicillin exposure impairs mouse alveolar development via Tet3-mediated hypo-hydroxymethylation of Nkx2-1 promoter.
PFOA substitute GenX at a sub-cytotoxic level exhibits thyroid-disrupting effects by inhibiting the expression of thyroid transcription factor 1.
Loss of CDKN2A Enhances the Efficacy of Immunotherapy in EGFR-Mutant Non-Small Cell Lung Cancer.
Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation.
Li W, Xia B, Geng X, Liu X, Wang M
Toxicology and applied pharmacology 2026 Jun;511:117817
Toxicology and applied pharmacology 2026 Jun;511:117817
PFOA substitute GenX at a sub-cytotoxic level exhibits thyroid-disrupting effects by inhibiting the expression of thyroid transcription factor 1.
He S, Xie C, Wang Y, Wang Y, Fan C, Su S, Qian M, Yang Y
Environmental pollution (Barking, Essex : 1987) 2025 Feb 15;367:125594
Environmental pollution (Barking, Essex : 1987) 2025 Feb 15;367:125594
Loss of CDKN2A Enhances the Efficacy of Immunotherapy in EGFR-Mutant Non-Small Cell Lung Cancer.
Wang S, Lai JC, Li Y, Tang C, Lu J, Han M, Ye X, Jia L, Cui W, Yang J, Wu C, Wang L
Cancer research 2025 Feb 1;85(3):585-601
Cancer research 2025 Feb 1;85(3):585-601
Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation.
Xu Q, Zhou L, Ri H, Li X, Zhang X, Qi W, Ye L
Environmental toxicology and pharmacology 2022 Nov;96:104007
Environmental toxicology and pharmacology 2022 Nov;96:104007
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 21777-1-AP(NKX2-1 antibody) at dilution of 1:1000
- Validation comment
- WB