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- References [4]
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- Product number
- ABIN1450126 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-NK2 Homeobox 1 (NKX2-1) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- 16 amino acid synthetic peptide near the amino terminus of Human NKX2-1
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas.
Mutations in TITF-1 are associated with benign hereditary chorea.
The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain.
Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity.
Kondo T, Nakazawa T, Ma D, Niu D, Mochizuki K, Kawasaki T, Nakamura N, Yamane T, Kobayashi M, Katoh R
Laboratory investigation; a journal of technical methods and pathology 2009 Jul;89(7):791-9
Laboratory investigation; a journal of technical methods and pathology 2009 Jul;89(7):791-9
Mutations in TITF-1 are associated with benign hereditary chorea.
Breedveld GJ, van Dongen JW, Danesino C, Guala A, Percy AK, Dure LS, Harper P, Lazarou LP, van der Linde H, Joosse M, Grüters A, MacDonald ME, de Vries BB, Arts WF, Oostra BA, Krude H, Heutink P
Human molecular genetics 2002 Apr 15;11(8):971-9
Human molecular genetics 2002 Apr 15;11(8):971-9
The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain.
Lazzaro D, Price M, de Felice M, Di Lauro R
Development (Cambridge, England) 1991 Dec;113(4):1093-104
Development (Cambridge, England) 1991 Dec;113(4):1093-104
Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity.
Guazzi S, Price M, De Felice M, Damante G, Mattei MG, Di Lauro R
The EMBO journal 1990 Nov;9(11):3631-9
The EMBO journal 1990 Nov;9(11):3631-9
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of NKX2-1 in rat lung tissue lysate with NKX2-1 antibody at (A) 1 and (B) 2 ug/mL.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of NKX2-1 in human lung tissue with NKX2-1 antibody at 2.5 ug/mL.
