FNab06543

antibody from FineTest Biotech

Targeting: PLEKHO1 CKIP-1, OC120

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab06543 - Provider product page
Provider: FineTest Biotech
Product name: PLEKHO1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein(CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2(CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity(plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: pleckstrin homology domain containi ng, family O member 1
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

PLEKHO1 protein structure - FNab06543 shown in red.