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- Product number
- 10828-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10828-1-AP, RRID:AB_2148585
- Product name
- c-Myc antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated c-MYC antibody (Cat. #10828-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Triptonide-mediated PTGS2 Inhibition Induces Autophagic Cell Death to Suppress the Progression of Triple-negative Breast Cancer and Epithelial Ovarian Cancer.
GSK3β as a potential regulator in AML: A pan-cancer multi-omics analysis.
SHP2 improved Late-onset fetal growth restriction via modulating ROS/BRD4/PI3K/YAP/PIGF signaling induced angiogenesis.
Exosome encapsulated albumin nanoparticles target delivery of DBET6 as a treatment for triple-negative breast cancer.
KIF23 Overexpression Promotes Cell Viability, Migration, and Invasion via the Wnt/β-Catenin Signaling Pathway in Anaplastic Thyroid Carcinoma.
Potential Anti-Cancer Drug 6RK73 Suppresses Ovarian Cancer Growth by Inactivating the AKT1/Sp1 Induced c-Myc Signaling Pathway.
Single-cell transcriptome analysis indicated that immune-related programmed cell death modification features could predict the clinical outcomes of patients with ovarian cancer.
Curcumin augments mitophagy via Nrf2-PINK1-mediated, Parkin-dependent ubiquitination to suppress ferroptosis in post-cardiac arrest brain injury.
Discovery of potent TNIK inhibitors containing a 1H-pyrrolo[2,3-b]pyridine scaffold as promising therapeutics for colorectal cancer.
The HSP90-dependent bioorthogonal PROTAC prodrug system enables tumor-selective and enhanced protein degradation.
Inhibiting mPGES-2 impedes renal cyst growth in mice with polycystic kidney disease.
Gallium-Doped MXene Nanozymes Protect Liver Through Multi-Death Pathway Blockade and Hepatocyte Regeneration.
Network medicine modeling of the m⁶A regulatory landscape identifies a KLF6-WTAP axis as a therapeutic target in pulmonary fibrosis.
tRF-3005a regulates exon skipping of SPAG4 by interacting with RALY to drive gastric cancer progression.
USP5-mediated CD73 deubiquitination drives osimertinib resistance via PI3K/AKT and glycolysis activation in LUAD.
Transcriptional readthrough precedes alternative splicing programs triggered in CML cells by imatinib.
KCTD1 stabilizes c-Myc to upregulate PD-L1 and suppress anti-tumor immunity in hepatocellular carcinoma.
OsCPN10a, cooperating with OsCPN20 and OsHSP60-3B negatively regulate ABA signaling and enhance seed storability in rice.
Heart-Specific and Conditional Deletion of the Immt Gene Reveals Its Role in Regulating Mitochondrial Structure and Total Heart Metabolism.
The role of FPR3 in remodeling the immune microenvironment and lung metastasis of colon adenocarcinoma.
Pyrimethamine regulates m6A modification of CCND1 via METTL14/YTHDF2 to inhibit hepatocellular carcinoma.
Aurintricarboxylic acid, an inhibitor of cystathionine γ-lyase, enhances the sensitivity of chemotherapy drugs in TNBC.
TAF1 acetyltransferase promotes colorectal carcinoma metastasis by catalyzing β-hydroxybutyrylation of KCTD9.
Targeting aldose reductase in pulmonary fibrosis: Blocking de novo fatty acid synthesis halts pro-fibrotic M2 polarization.
Triglyceride lipase PNPLA2-independent suppression of c-MYC signaling by the metabolic coactivator ABHD5 in prostate cancer.
SPON2 acts as a tumor promoter in HR-positive/HER2-negative breast cancer by regulating β-catenin signaling.
Pan-cancer multi-omics reveals DCAF7 as an immune-modulating prognostic driver and Wnt/β-catenin activator in hepatocellular carcinoma.
PPIA regulates fatty acid and glutamine metabolism in lung adenocarcinoma based on multiomics prognostic model and experiment validation.
Suppressing the Aberrant Transcriptional Functionality of EWS::FLI1 Oncoprotein by Designer polyQ Fusions with Its Homologous Peptides.
Inhibition of the RORC/GPX4 mediated ferroptosis regulatory axis suppresses tumor growth and alleviates enzalutamide resistance in prostate cancer.
Neutrophil-derived exosomes inhibit gastric cancer progression via miR-101-3p-mediated suppression of MCL1.
Upregulated ARMCX1 suppresses nasopharyngeal carcinoma progression by promoting TRIM21-mediated β-catenin degradation.
SOX2 is a dispensable modulator of NUT carcinoma oncogenesis in mice.
The Deubiquitinating Enzyme USP46 Abolishes Cell Survival of Prostate Cancer via Enhancing BECN1-Dependent Autophagy.
Role of the transmembrane domain in severe acute respiratory syndrome (SARS) coronavirus 2 spike for palmitoylation and membrane fusion.
NRAV promotes HCC stemness via the m6A-regulated let-7c-5p/LIN28B axis.
Exploring the potential mechanisms of PFAS exposure on colorectal cancer via combined bioinformatics analyses and experiments.
A novel PVA/QCS/AgNP hydrogel with antibacterial and healing-promoting efficacy for preventing postoperative pancreatic fistula in rats.
Tissue-Resident Macrophage-Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p-TBK1.
PRKD1/EIF5A/β-catenin axis inhibits tumorigenesis and metastasis in non-small-cell lung cancer.
Antioxidant and Anti-Aging Effects of Porphyra-334 Produced from Saccharomyces cerevisiae in Human Skin Models.
A DNA Methylation-Dependent NOP56/MYC Positive Feedback Loop Promotes the Proliferation and Migration of Non-Small Cell Lung Cancer Through Regulating Ribosome Biogenesis.
DNMT3b promotes proliferation and invasion by mediating HOPX DNA methylation in lung cancer.
MUL1 suppresses cervical cancer progression by targeting FUNDC1 for ubiquitination and inhibiting DRP1-dependent mitophagy.
Asporin regulates glycolysis and stemness of gastric cancer cells.
KIF20A inhibits TRIM21-dependent ubiquitination of DHX9 to boost SOX2 stability, enhancing OSCC stemness and ferroptosis resistance.
Structural characterization and anti-hepatic fibrosis effects of a novel polysaccharide from Astragalus complanatus seeds.
cGAS-STING Pathway-Induced BST2 Enhances HPV-Infected Keratinocyte Proliferation in Condyloma Acuminata.
Angiopep-2-decorated bacterial outer membrane vesicles penetrate the blood-brain barrier for glioblastoma chemo-immunotherapy.
Genetic and pharmaceutical manipulation of H3K9 methyltransferase Suv39h1 promotes liver regeneration by unleashing HMGB2 transcription.
miRNA‑378a‑5p attenuates the development of abdominal aortic aneurysm via ABLIM1‑MKL1 signaling pathways.
Marek's disease virus hijacks host nucleotide metabolism via UL23-mediated c-Myc activation.
The RNA methyltransferase NSUN2 catalyzes 5-methylcytosine (m(5)C) on IL1B mRNA to promote transcript stability.
Epigenetic H3K4me3 activation of miR-155-5p promotes intervertebral disc degeneration via autophagy and ageing in nucleus pulposus cells.
Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression.
Hsp70-Targeting Chimeras Enable Dual Proteasomal and Lysosomal Degradation of Intracellular and Extracellular Proteins.
MYC Addiction as a Targetable Vulnerability in Nelarabine-Resistant T-Cell Acute Lymphoblastic Leukemia.
AnnoNet-TCMs: An annotation network-driven discovery of novel active compounds and mechanisms in traditional Chinese medicine.
Metformin hydrochloride regulates glycolysis and inhibits PEDV replication by inhibition of PI3K-AKT signaling pathway.
CGF induces ROS-mediated metabolic reprogramming and mitochondrial dysfunction to suppress colorectal cancer progression.
KIAA1429 promotes clear cell renal cell carcinoma progression by regulating MYC mRNA stability.
KRT15 identified by scRNA-Seq and machine learning as stemness regulator and prognostic biomarker in ESCC.
Neddylation of STAT3 is a potential therapeutic target for MASLD.
African swine fever virus pE199L, as a mitophagy receptor, suppresses antiviral innate immunity to promote viral replication.
Copper Transporter 1‑Mediated Deregulation of Copper Homeostasis Impacts MYC and Oxidative Phosphorylation Pathways and Increases the Sensitivity of Tumor Cells to Complex I Inhibitors.
CDK4/6 and BET inhibitors synergistically suppress pancreatic tumor growth and epithelial-to-mesenchymal transition by regulating the GSK3β-mediated Wnt/β-catenin pathway.
CYMP-AS1 Promotes Ovarian Cancer Progression by Enhancing the Intracellular Translocation of hnRNPM and Reducing the Stability of AXIN2 mRNA.
circACTN4 promotes breast cancer cell cycle progression and oncogenesis via c-MYC induced histone H4 acetylation.
Splicing factor PTBP1 promotes hepatocarcinogenesis via oncogenic splice-switching of MAPT.
ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway.
TMEM105 modulates disulfidptosis and tumor growth in pancreatic cancer via the β-catenin-c-MYC-GLUT1 axis.
Platycodin D Enhances Glioma Sensitivity to Temozolomide by Inhibition of the Wnt/β-Catenin Pathway.
MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma.
T cell-mediated immune surveillance conferred by latent Epstein-Barr virus genes suppresses a broad spectrum of tumor formation through NKG2D-NKG2DL interactions.
LINC01559 drives osimertinib resistance in NSCLC through a ceRNA network regulating miR-320a/IGF2BP3 axis.
Gut microbiota-derived metabolite phenylacetylglutamine inhibits the progression of prostate cancer by suppressing the Wnt/β-catenin signaling pathway.
Human fibrosarcoma cells selected for ultra-high doxorubicin resistance, acquire trabectedin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression.
Developing a prognostic stratification model based on glutathione metabolism in thyroid cancer and validating RRM2's tumor-promoting role.
CMSP suppresses oral squamous cell carcinoma progression by targeting the JAK2/STAT3/c-Myc axis.
Targeting the N-cadherin/β-catenin axis with MSAB reverses malignant phenotypes in blast crisis of CML.
O-GlcNAcylation of YTHDF2 antagonizes ERK-dependent phosphorylation and inhibits lung carcinoma.
METTL3 Mediates Wnt/β-Catenin Pathway in Epithelial-Mesenchymal Transition of 16HBE Cells Induced by Beryllium Sulphate.
ZMYND8 promotes the Warburg effect and tumorigenesis through c-Myc activation in pancreatic cancer.
A Small Molecular Weight Saccharide Fraction From Panax quinquefolium L. Inhibited Non-Small Cell Lung Cancer via Endoplasmic Reticulum-Stress Mediated Apoptosis.
The chromatin remodeling factor BAP18 promotes non-small cell lung cancer progression via the recruitment of β-catenin with the transcriptional coactivator complex ACTL6A-PAF1.
LRK10L3 and BAK1 are collaboratively involved in extracellular ATP-regulated seedling growth of Arabidopsis thaliana.
H3K36me3-Guided m(6)A Modification of Oncogenic L1CAM-AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma.
Low-intensity pulsed ultrasound stimulation to treat renal fibrosis through inhibiting tubular IL-1R.
Cytoplasmic TRIM24 promotes colorectal cancer cell proliferation by activating Wnt/β-catenin signaling.
YTHDF2 alleviates the radioresistance of rectal cancer cells by targeting methylated MYC.
Kuwanon A Targeted YWHAB in Hepatocellular Carcinoma Cells to Inhibit the Raf/MEK/ERK Signaling Pathway.
Slow-Release Prostacyclin Agonist-Immersed Sheet Implantation Suppresses Liver Fibrosis via Hippo Signaling Pathway Activation.
S100A9 promotes resistance to anti-PD-1 immunotherapy in hepatocellular carcinoma by degrading PARP1 and activating the STAT3/PD-L1 pathway.
Reprogramming Iron Metabolism via the RIG-I/c-Myc/FTH Axis Mitigates Renal Ischemia-Reperfusion Injury.
USP45 Represses Melanoma Development by Deubiquitinating and Stabilizing Tumor Suppressor MRGPRF.
HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancer.
MDA-9/Syntenin promotes glioma cell proliferation and invasion via exosome-mediated activation of the PI3K-AKT signaling pathway.
Canagliflozin inhibits hepatic stellate cells activation and proliferation by inhibiting PP2A-mediated β-catenin dephosphorylation to attenuate hepatic fibrosis.
TRIM21 as a potential prognostic biomarker and therapeutic target affects the growth of pancreatic cancer.
RPL22L1-Myc positive feedback loop drives lung adenocarcinoma progression.
Deacetylation of TALDO1 by HDAC6 promotes glycolysis and nasopharyngeal carcinoma progression through a moonlighting function.
Pan-cancer analysis of role of LOXL4 and experiment validation in osteosarcoma.
ALKBH8-mediated codon-specific translation promotes colorectal tumorigenesis.
Cedrol impedes lung cancer metastasis by reducing tumor-associated macrophage polarization mediated by MYC-driven aerobic glycolysis.
Obesity induced by a high-fat diet regulates the MYC‒PPIL1 network in the mediation of asthenozoospermia.
Centromere protein I facilitates breast cancer tumorigenesis and disease progression through modulation of Wnt/β-Catenin signaling.
Long noncoding RNA ENST00000458139 promotes mitochondrial dysfunction and apoptosis of podocytes in diabetic kidney disease through binding with SNRPA1.
KIF23 silencing suppresses papillary thyroid carcinoma metastasis by regulating mitophagy via Wnt/β-catenin pathway.
TRIM39-mediated deubiquitination upregulates RNF168 to evade autophagy-ferroptosis in triple-negative breast cancer.
Integrating network pharmacology and pharmacological evaluation for investigating the active ingredient of Chinese herbal formula Zhuhuang Granule in psoriasis.
Glioma cells produce soluble PD-L1 via the Wnt/β-catenin signaling pathway to suppress CD8+ T cell activity.
Fragile X mental retardation 1 gene FMR1 promotes proliferation, migration, and invasion of gastric cancer cells via c-MYC.
USP30-AS1 Dictates Breast Cancer Cell Fate and Chemoresistance via a miR-3646/FZD7/Wnt/β-Catenin Circuit.
CDC26 facilitates ferroptosis through SLC7A11 degradation and cell cycle arrest.
Transcriptional readthrough precedes alternative splicing programs triggered in CML cells by imatinib.
Phytosphingosine suppresses gastric cancer through SFRP4/β-catenin axis-mediated Wnt signaling pathway inhibition.
Phospho-TRIM21 orchestrates RPA2 ubiquitination switch to promote homologous recombination and tumor radio/chemo-resistance.
The selenocysteine-containing protein SELENOT maintains dopamine signaling in the midbrain to protect mice from hyperactivity disorder.
Histone acetyltransferase BmMOF inhibits the proliferation of the Bombyx mori nucleopolyhedrovirus by targeting Bmp53.
Foxp3 inhibits PCV2 replication by reducing the ATPase activity of Rep.
HKDC1 promotes colorectal cancer progression by regulating RCOR1 expression to activate the Wnt/β-catenin pathway, enhancing proliferation, migration, and epithelial-mesenchymal transition.
Role of noncanonical histone H2A variant, H2A.Z, to maintain proper centromeric transcription and chromosome segregation.
The Role of PAX7 in Breast Cancer Prognosis and Its Mechanistic Involvement in the Wnt/β-Catenin Pathway.
PTPRG-AS1 regulates the KITLG/KIT pathway through the ceRNA axis to promote the malignant progression of gastric cancer and the intervention effect of Compound Kushen injection on it.
Paclitaxel alleviates spinal cord injury via activation of the Wnt/β-catenin signaling pathway.
Overexpression of c-Myc triggers p62 aggregation-mediated mitochondrial mitophagy in cabozantinib resistance of hepatocellular carcinoma.
NOTCH1 inhibition enhances immunogenicity and sensitizes triple-negative breast cancer to immune checkpoint inhibitors.
NCOA5 induces sorafenib resistance in hepatocellular carcinoma by inhibiting ferroptosis.
Exploration of the pharmacological substance basis and efficacy evaluation of fufang she-she-cao (Hedyotis diffusa formula) in repressing gastric cancer.
HBV core protein enhances WDR46 stabilization to upregulate NUSAP1 and promote HCC progression.
Penta-1,4-dien-3-one and quinoxaline conjugates as potential anticancer agents via inhibiting EphB3/SRC/AKT axis.
Targeting ADAR1 with a small molecule for the treatment of prostate cancer.
CircXPO6 promotes breast cancer progression through competitively inhibiting the ubiquitination degradation of c-Myc.
Long Noncoding RNA E2F1 Messenger RNA Stabilizing Factor (EMS) Promotes Sorafenib Resistance in Renal Cell Carcinoma by Regulating miR-363-3p and Dual-Specificity Phosphatase 10 Expression.
The MCM6-c-Myc positive feedback loop mediates bladder cancer progression and cisplatin resistance.
Mechanism of β-Catenin in Pulmonary Fibrosis Following SARS-CoV-2 Infection.
Targeting NETO2 suppresses cell proliferation, invasion, and migration and inactivates the STAT3/C-MYC pathway in hepatocellular carcinoma.
ORMDL3 restrains type I interferon signaling and anti-tumor immunity by promoting RIG-I degradation.
Deletion of ENO1 sensitizes pancreatic cancer cells to gemcitabine via MYC/RRM1-mediated glycolysis.
CHI3L1: a key driver in gastritis-to-cancer transformation.
Design of Selective BRD4 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease.
TOP2A Promotes Proliferation, Migration, and Inflammatory Response in M5-Treated Keratinocytes by Binding CTBP1 to Activate Wnt/β-Catenin Signaling.
Discovery of 5-imidazole-3-methylbenz[d]isoxazole derivatives as potent and selective CBP/p300 bromodomain inhibitors for the treatment of acute myeloid leukemia.
A positive feedback loop of OTUD1 and c-Jun driven by leptin expedites stemness maintenance in ovarian cancer.
Targeting Myc through BET-PROTAC elicits potent anti-lymphoma activity in diffuse large B cell lymphoma.
Interaction of osteopontin with α-lactalbumin and their synergistic effects in protecting intestinal barrier injury.
Circovirus Rep evades immune restriction by disrupting cGAS oligomerization and phase separation.
SGLT2i delays c-Myc-induced HCC progression via targeting mTOR.
Targeting the MDK/c-Myc complex to overcome temozolomide resistance in glioma.
KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β-Catenin Signaling Pathway.
Duodenal Adenocarcinoma Is Characterized by Acidity, High Infiltration of Macrophage, and Activated Linc01559-GRSF1 Axis.
Serine/threonine/tyrosine kinase 1 drives pancreatic carcinogenesis via GSK3β sequestration-mediated Wnt/β-catenin pathway hyperactivation.
PGK1 phosphorylates NLRP3 and mediates inflammasome activation independent of its glycolytic activity.
Cytohesin-4/ARF6 facilitates the progression of acute myeloid leukemia through activating PIK3R5/PI3K/AKT pathway.
SLC3A2-Mediated Lysine Uptake by Cancer Cells Restricts T-cell Activity in Hepatocellular Carcinoma.
BRD9 promotes the malignant phenotype of thyroid cancer by activating the MAPK/ERK pathway.
Single-Cell and Spatial Transcriptomics Identified Fatty Acid-Binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension.
Chronic prostatitis/chronic pelvic pain syndrome impairs erectile function by inducing apoptosis in a rat model of experimental autoimmune prostatitis.
HBx Drives Liver Cancer Stem Cell Generation Through Stimulating Glucose Metabolic Reprogramming.
MTMR regulates KRAS function by controlling plasma membrane levels of phospholipids.
The scaffold protein DLG4 facilitates RNF63-mediated ubiquitination and degradation of STAT3 in non-small cell lung cancer.
Metabolomics and proteomics reveal blocking argininosuccinate synthetase 1 alleviates colitis in mice.
Genetic modulation of lncPSMB1 confers non-syndromic cleft lip with or without cleft palate susceptibility by promoting cell apoptosis.
Design, Synthesis, and Activity Evaluation of Novel Nucleosides as ADAR1 Inhibitor for the Treatment of Prostate Cancer.
Modulatory Effect of Curcumin on Expression of Methyltransferase/Demethylase in Colon Cancer Cells: Impact on wt p53, mutp53 and c-Myc.
Keratin 6A Overexpression in the Lymphovascular Invasion-Associated Tumor Subgroup Promotes Progression of Triple-Negative Breast Cancer.
SOX2 is a dispensable modulator of NUT carcinoma oncogenesis in mouse.
Sialidase NEU3 silencing inhibits angiogenesis of EA.hy926 cells by regulating Wnt/β-catenin signaling pathway.
Inhibiting the Otub1/phosphorylated STAT3 axis for the treatment of non-small cell lung cancer.
A peptide encoded by LINC00944 suppresses the growth of melanoma cells by diminishing EP400-MYC interaction.
CqProfilin enhances WSSV infection by promoting viral intracellular transport through binding to both viral nucleocapsid and actin cytoskeleton.
IRAK2 overexpression restrains prostate cancer progression by regulation of TRAF6 ubiquitination.
FAM49B drives colorectal cancer progression by stabilizing c-Myc through NEK9 phosphorylation.
Elevated-c-MYC-expressing Fibrosarcoma Cells With Acquired Gemcitabine Resistance Remain Sensitive to Recombinant Methioninase: A Potential Clinical Strategy for a Recalcitrant Disease.
LRP11 facilitates lipid metabolism and malignancy in hepatocellular carcinoma by stabilizing RACK1 through USP5 regulation.
Jiedu Xiaozheng Yin extract targets cancer stem cells by Wnt signaling pathway in colorectal cancer.
CASC8 activates the pentose phosphate pathway to inhibit disulfidptosis in pancreatic ductal adenocarcinoma though the c-Myc-GLUT1 axis.
Bletilla striata polysaccharide-mediated trained immunity drives the hematopoietic progenitors' expansion and myelopoiesis.
Ubiquitin-conjugating enzyme E2T confers chemoresistance of colorectal cancer by enhancing the signal propagation of Wnt/β-catenin pathway in an ERK-dependent manner.
Targeted Degradation of HCV Polymerase by GalNAc-Conjugated ApTACs for Pan-Genotypic Antiviral Therapy with High Resistance Barriers.
Structure-Based Rational Design and Evaluation of BET-Aurora Kinase Dual-Inhibitors for Treatment of Cancers.
miR-28-3p suppresses gastric cancer growth and EMT-driven metastasis by targeting the ARF6/Hedgehog axis.
NEK2 Promotes ESCC Malignant Progression by Inhibiting Cellular Senescence via the FOXM1/c-Myc/p27 Signaling Pathway.
β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis.
METTL5 Promotes Tumor Progression in Oral Squamous Cell Carcinoma by Activating the Myc Pathway.
ZIP8 Regulates Inflammation and Macrophage Polarisation in Intervertebral Disc Degeneration via the Wnt/β-Catenin Pathway.
Enhanced Oxidative Phosphorylation Driven by TACO1 Mitochondrial Translocation Promotes Stemness and Cisplatin Resistance in Bladder Cancer.
PNPO-Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β-Catenin Pathway.
PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53.
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
SJB2-043, a USP1 Inhibitor, Suppresses A549 Cell Proliferation, Migration, and EMT via Modulation of PI3K/AKT/mTOR, MAPK, and Wnt Signaling Pathways.
Overexpressed NEK2 contributes to progression and cisplatin resistance through activating the Wnt/β-catenin signaling pathway in cervical cancer.
A novel 5'tRNA-derived fragment tRF-Tyr inhibits tumor progression by targeting hnRNPD in gastric cancer.
Unraveling the miR-144-3p/PUMA pathway: a novel regulator of FDX1-mediated cuproptosis in colorectal cancer.
Pan-cancer analysis identifies adhesion G protein-coupled receptor G6 as a potential prognostic and immunotherapeutic biomarker with its functional validation.
Targeting TRAF6 inhibits cystogenesis in autosomal dominant polycystic kidney disease.
Terpine-4-ol alleviates lipopolysaccharide-induced intestinal injury in weaned piglets by regulating intestinal epithelial cell homeostasis via the Wnt/β-catenin signaling pathway.
A novel lncRNA, Lnc21q22.11, suppresses gastric cancer growth by inhibiting MEK/ERK pathway.
N2 neutrophils induce cell stemness reprogramming to promote gastric cancer progression via exosomal miRNAs.
Multi-omics analysis reveals that ALYREF-mediated m(5)C modification promotes platinum resistance in ovarian cancer via the NSUN2/ALYREF/LGR4 axis.
LGR5 interacts with HSP90AB1 to mediate enzalutamide resistance by activating the WNT/β-catenin/AR axis in prostate cancer.
Bruceine D promotes TNBC regression by inhibiting M2-like tumor-associated macrophage polarization induced Wnt3a/β-catenin pathway.
EXOSC3 knockdown induces G1/S phase arrest to suppress hepatocellular carcinoma cell proliferation.
piR-hsa-022095 Drives Hypertrophic Scar Formation via KLF11-Dependent Fibroblast Proliferation.
Aurora A degradation by HSP90 interactome-mediating PROTACs in A549 and paclitaxel-resistant A549 cells.
CUL4B promotes hepatocellular carcinoma progression and oxaliplatin resistance by facilitating FUS degradation.
THOC1 binds to U2AF2 and regulates ovarian cancer progression through the beta-catenin / c-myc / cyclinD1 signaling pathway.
Machine learning-based identification of kbhb-affected tumor cell subsets as prognostic and therapeutic targets in breast cancer.
Repetitive unidirectional spinal tactile stimulation engages microglial Bmal1 pathways to promote synaptic remodeling in the mPFC of adolescent VPA-exposed mice.
METTL1-driven epitranscriptomic enhancement of TXNDC12 boosts c-Myc stability through USP5 in HNSCC.
Dujieqing decoction suppresses multiple myeloma growth by inhibiting the Wnt/β-catenin pathway.
Inhibition of UCH-L1 enhances immunotherapy efficacy in triple-negative breast cancer by stabilizing PD-L1.
Extrachromosomal DNA biogenesis is dependent on DNA looping and religation by YY1-Lig3-PARylation complex.
Drug-Free Approach to Regulate Undruggable Proto-Oncogene MYC Using Biomimetic Porous Nanoparticles for Cancer Immunotherapy.
ICAM-1-mediated Src signaling pathway plays a pivotal role in encephalomyocarditis virus entry.
CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability.
Resveratrol induces ferroptosis in triple-negative breast cancer through NEDD4L-mediated GPX4 ubiquitination and degradation.
Investigating the Mechanism of IFN-γ-Inducible Lysosomal Thiol Reductase-Mediated Inhibition of Breast Cancer Cell Proliferation.
PLEKHA4 knockdown induces apoptosis in melanoma cells through the MAPK and β‑catenin signaling pathways.
N6-methyladenosine-mediated EIF3H promotes anaplastic thyroid cancer progression and ferroptosis resistance by stabilizing β-catenin.
Shengjiang Xiexin Decoction ameliorates DSS-induced ulcerative colitis via activating Wnt/β-Catenin signaling to enhance epithelium renovation and modulating intestinal flora.
Targeting the Adenosine-Mediated Metabolic Immune Checkpoint with Engineered Probiotic for Enhanced Chemo-Immunotherapy.
Nuclear to Cytoplasmic Transport Is a Druggable Dependency in HDAC7-driven Small Cell Lung Cancer.
Cannabidiol Enhances the Anticancer Activity of Etoposide on Prostate Cancer Cells.
Endothelial USP11 drives VEGFR2 signaling and angiogenesis via PRDX2/c-MYC axis.
Modulation of Intestinal Barrier Function and Wnt/β- Catenin Pathway by Sanzi Formula in Colorectal Adenoma Development.
Development of Novel PRMT7 Inhibitors for the Treatment of Prostate Cancer.
PRMT5-mediated methylation of METTL3 promotes cisplatin resistance in ovarian cancer by facilitating DNA repair mechanisms.
The role of IGF2BP3/SPOP/c-Myc loop in paclitaxel resistance of endometrial cancer.
Porcine reproductive and respiratory syndrome virus nsp5 inhibits the activation of the Nrf2/HO-1 pathway by targeting p62 to antagonize its antiviral activity.
LINC02167 stabilizes KSR1 mRNA in an m(5)C-dependent manner to regulate the ERK/MAPK signaling pathway and promotes colorectal cancer metastasis.
The dual HDAC/PI3K inhibitor CUDC-907 inhibits the growth and proliferation of MYC-driven Group 3 medulloblastoma.
Astragaloside IV Ameliorates Colonic Adenomatous Polyps Development by Orchestrating Gut Bifidobacterium and Serum Metabolome.
IL13RA2 promotes progression of infantile haemangioma by activating glycolysis and the Wnt/β-catenin signaling pathway.
The m6A modification-mediated positive feedback between glycolytic lncRNA SLC2A1-DT and c-Myc promotes tumorigenesis of hepatocellular carcinoma.
VEGFA/NRP-1/GAPVD1 axis promotes progression and cancer stemness of triple-negative breast cancer by enhancing tumor cell-macrophage crosstalk.
MPP7 mediates EMT via Wnt/β-catenin pathway to promote polarity changes in epithelial ovarian cancer cells.
African swine fever virus structural protein p17 inhibits IRF3 activation by recruiting host protein PR65A and inducing apoptotic degradation of STING.
Chidamide represses MYC expression and might improve survival for patients with double expressor lymphoma.
High glucose-induced NCAPD2 upregulation promotes malignant phenotypes and regulates EMT via the Wnt/β-catenin signaling pathway in HCC.
Anillin contributes to prostate cancer progression through the regulation of IGF2BP1 to promote c-Myc and MAPK signaling.
Comprehensive analysis of ferroptosis-related genes indicates that TRIM46 is a novel biomarker and promotes the progression of ovarian cancer via modulating ferroptosis and Wnt signaling pathway.
The role of VANGL2 in glioma oncogenesis and progression: insights into expression profiles and prognostic relevance.
Vitamin D-metabolizing enzyme CYP24A1 affects oncogenic behaviors of oral squamous cell carcinoma and its prognostic implication.
Novel circular RNA hsa_circ_0036683 suppresses proliferation and migration by mediating the miR-4664-3p/CDK2AP2 axis in non-small cell lung cancer.
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation.
Novel potent molecular glue degraders against broad range of hematological cancer cell lines via multiple neosubstrates degradation.
ARMCX1 inhibits lung adenocarcinoma progression by recruiting FBXW7 for c-Myc degradation.
Study on the mechanism of macrophages activated by phosphoesterified rehmanniae polysaccharide on human gastric cancer cells.
Targeting SNAI1-Mediated Colorectal Cancer Chemoresistance and Stemness by Sphingosine Kinase 2 Inhibition.
N-acetylgalactosaminyltransferase GALNT6 is a potential therapeutic target of clear cell renal cell carcinoma progression.
CHAC1 blockade suppresses progression of lung adenocarcinoma by interfering with glucose metabolism via hijacking PKM2 nuclear translocation.
RHOF promotes Snail1 lactylation by enhancing PKM2-mediated glycolysis to induce pancreatic cancer cell endothelial-mesenchymal transition.
Inhibition of UBE2N in regulatory T-cells boosts immunity against cancer.
A TBK1-independent primordial function of STING in lysosomal biogenesis.
NSUN2 regulates Wnt signaling pathway depending on the m5C RNA modification to promote the progression of hepatocellular carcinoma.
Oncogenic accumulation of cysteine promotes cancer cell proliferation by regulating the translation of D-type cyclins.
PELO regulates erythroid differentiation through interaction with MYC to upregulate KLF10.
The miR-665/SOST Axis Regulates the Phenotypes of Bone Marrow Mesenchymal Stem Cells and Osteoporotic Symptoms in Female Mice.
Epigenetic regulation of noncanonical menin targets modulates menin inhibitor response in acute myeloid leukemia.
Oncogenic RTKs sensitize cancer cells to ferroptosis via c-Myc mediated upregulation of ACSL4.
Chemo-Enzymatic Functionalization of Bovine Milk Exosomes with an EGFR Nanobody for Target-specific Drug Delivery.
Protein profile of mouse endolymph suggests a role in controlling cochlear homeostasis.
Inhibition of NPC1 suppresses cell proliferation and β-catenin signaling activation of liver cancer.
Multiomics profiling uncovers curdione-induced reproductive toxicity in HTR-8/SVneo cells.
Immune Checkpoint-Modulating Photosensitizer That Targets BRD4 for Cancer Photoimmunotherapy.
N-Acetylneuraminic acid triggers endothelial pyroptosis and promotes atherosclerosis progression via GLS2-mediated glutaminolysis pathway.
Prognostic and immunotherapeutic implications of bilirubin metabolism-associated genes in lung adenocarcinoma.
Alkenyl oxindole is a novel PROTAC moiety that recruits the CRL4DCAF11 E3 ubiquitin ligase complex for targeted protein degradation.
A novel combined therapeutic strategy of Nano-EN-IR@Lip mediated photothermal therapy and stem cell inhibition for gastric cancer.
Pervasive structural heterogeneity rewires glioblastoma chromosomes to sustain patient-specific transcriptional programs.
ZDHHC20-mediated S-palmitoylation of YTHDF3 stabilizes MYC mRNA to promote pancreatic cancer progression.
Transcriptional Up-Regulation of FBXW7 by K(Ca)1.1 K(+) Channel Inhibition through the Nrf2 Signaling Pathway in Human Prostate Cancer LNCaP Cell Spheroid Model.
CXCL4:NLRP3-mediated pyroptosis product that regulates cardiac fibrosis.
ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis.
Targeted degradation of oncogenic BCR-ABL by silencing the gene of NEDD8 E3 ligase RAPSYN.
HSPB8 binding to c-Myc alleviates hypoxia/reoxygenation-induced trophoblast cell dysfunction.
Targeting carnitine palmitoyl transferase 1A (CPT1A) induces ferroptosis and synergizes with immunotherapy in lung cancer.
TREM2 deficiency impairs the energy metabolism of Schwann cells and exacerbates peripheral neurological deficits.
EIF2Ss, a Novel c-Myc-Correlated Gene Family, is Associated with Poor Prognosis and Immune Infiltration in Pancreatic Adenocarcinoma.
Pan-cancer analysis of DDIT4 identifying its prognostic value and function in acute myeloid leukemia.
5-AZA Upregulates SOCS3 and PTPN6/SHP1, Inhibiting STAT3 and Potentiating the Effects of AG490 against Primary Effusion Lymphoma Cells.
An integrated investigation of sulfotransferases (SULTs) in hepatocellular carcinoma and identification of the role of SULT2A1 on stemness.
YTHDF1 regulates immune cell infiltration in gastric cancer via interaction with p53.
METTL3 orchestrates glycolysis by stabilizing the c-Myc/WDR5 complex in triple-negative breast cancer.
HnRNPA2B1 ISGylation Regulates m6A-Tagged mRNA Selective Export via ALYREF/NXF1 Complex to Foster Breast Cancer Development.
OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway.
SAHA/5-AZA Enhances Acetylation and Degradation of mutp53, Upregulates p21 and Downregulates c-Myc and BRCA-1 in Pancreatic Cancer Cells.
TRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation.
MEX3A promotes colorectal cancer migration, invasion and EMT via regulating the Wnt/β-catenin signaling pathway.
Identified γ-glutamyl cyclotransferase (GGCT) as a novel regulator in the progression and immunotherapy of pancreatic ductal adenocarcinoma through multi-omics analysis and experiments.
C-MYC-activated lncRNA SNHG20 accelerates the proliferation of diffuse large B cell lymphoma via USP14-mediated deubiquitination of β-catenin.
The Selective SIRT3 Inhibitor 3-TYP Represses Primary Myeloma Growth by Reducing c-Myc Stability.
MYG1 drives glycolysis and colorectal cancer development through nuclear-mitochondrial collaboration.
Overexpression of FHL1 suppresses papillary thyroid cancer proliferation and progression via inhibiting Wnt/β-catenin pathway.
Brd4::Nutm1 fusion gene initiates NUT carcinoma in vivo.
NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance.
Major Facilitator Superfamily Domain Containing 12 Is Overexpressed in Lung Cancer and Exhibits an Oncogenic Role in Lung Adenocarcinoma Cells.
Exploring the key genes associated with breast cancer radiotherapy sensitivity based on the stromal-immune score and analysis of the WGCNA and ceRNA network.
Semaphorin 3C (Sema3C) reshapes stromal microenvironment to promote hepatocellular carcinoma progression.
Screening and identification of miRNAs negatively regulating FAM83A/Wnt/β-catenin signaling pathway in non-small cell lung cancer.
Disintegration of Cav-1/β-catenin complex attenuates neuronal death after ischemia-reperfusion injury by promoting β-catenin nuclear translocation.
Repurposing AS1411 for constructing ANM-PROTACs.
CD24 promotes metastasis and chemoresistance by directly targeting Arf6-ERK pathway in esophageal squamous cell carcinoma.
3'-Hydroxypterostilbene Potently Suppresses Tumor Growth via Inhibiting the Activation of the JAK2/STAT3 Pathway in Ovarian Clear Cell Carcinoma.
Circular RNA circXPO1 Promotes Multiple Myeloma Progression by Regulating miR-495-3p/DNA Damage-Induced Transcription 4 Axis.
Arginine-methylated c-Myc affects mitochondrial mitophagy in mouse acute kidney injury via Slc25a24.
MYSM1 acts as a novel co-activator of ERα to confer antiestrogen resistance in breast cancer.
Effects and mechanisms of frehmaglutin D and rehmaionoside C improve LPS-induced acute kidney injury through the estrogen receptor-mediated TLR4 pathway in vivo and in vitro.
Taxifolin inhibits melanoma proliferation/migration impeding USP18/Rac1/JNK/β-catenin oncogenic signaling.
Deubiquitinase OTUB1 regulates doxorubicin-induced cardiotoxicity via deubiquitinating c-MYC.
The feedback loop of EFTUD2/c-MYC impedes chemotherapeutic efficacy by enhancing EFTUD2 transcription and stabilizing c-MYC protein in colorectal cancer.
Characterization and verification of CD81 as a potential target in lung squamous cell carcinoma.
TRIM56 protects against nonalcoholic fatty liver disease by promoting the degradation of fatty acid synthase.
Npc1 gene mutation abnormally activates the classical Wnt signalling pathway in mouse kidneys and promotes renal fibrosis.
Efficacy of Yisui granule on myelodysplastic syndromes in SKM-1 mouse xenograft model through suppressing Wnt/β-catenin signaling pathway.
LATS1/YAP1 Axis Controls Bone Regeneration on Distraction Osteogenesis by Activating Wnt/β-Catenin.
Tumor suppressive function of IGF2BP1 in gastric cancer through decreasing MYC.
Protein phosphatase 1 regulatory subunit 15 A promotes translation initiation and induces G2M phase arrest during cuproptosis in cancers.
Curcumin triggers the Wnt/β-catenin pathway and shields neurons from injury caused by intermittent hypoxia.
Icariin ameliorates Coxsackievirus B3-induced viral myocarditis by modulating the S100 calcium binding protein A6/β-catenin/c-Myc signaling pathway.
MiR-135b-5p promotes cetuximab resistance in colorectal cancer by regulating FOXN3.
RBIS regulates ribosome biogenesis to affect progression in lung adenocarcinoma.
Curcumin activates the Wnt/β-catenin signaling pathway to alleviate hippocampal neurogenesis abnormalities caused by intermittent hypoxia: A study based on network pharmacology and experimental verification.
TFAP2C-mediated transcriptional activation of STEAP3 promotes lung squamous cell carcinoma progression by regulating the β-catenin pathway.
Modeling gastric intestinal metaplasia in 3D organoids using nitrosoguanidine.
The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release.
Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signaling.
Dysfunction of astrocytic glycophagy exacerbates reperfusion injury in ischemic stroke.
Overcoming retinoic acid resistance in HER2-enriched breast cancers: role of MYC.
P4HA3 promotes head and neck squamous cell carcinoma progression via the WNT/β-catenin signaling pathway.
Epigenetic repression of de novo cysteine synthetases induces intra-cellular accumulation of cysteine in hepatocarcinoma by up-regulating the cystine uptake transporter xCT.
Inhibition of KIF20A enhances the immunotherapeutic effect of hepatocellular carcinoma by enhancing c-Myc ubiquitination.
DNA damage response-related signatures characterize the immune landscape and predict the prognosis of HCC via integrating single-cell and bulk RNA-sequencing.
Progesterone (P4) ameliorates cigarette smoke-induced chronic obstructive pulmonary disease (COPD).
CUDC-907 exhibits potent antitumor effects against ovarian cancer through multiple in vivo and in vitro mechanisms.
RAE1 promotes gastric carcinogenesis and epithelial-mesenchymal transition.
Pyrogallol promotes growth arrest by activating the p53-mediated up-regulation of p21 and p62/SQSTM1-dependent degradation of β-catenin in nonsmall cell lung cancer cells.
Integrative analysis unveils ECM signatures and pathways driving hepatocellular carcinoma progression: A multi-omics approach and prognostic model development.
Cellular nucleic acid binding protein facilitates cardiac repair after myocardial infarction by activating β-catenin signaling.
Inhibition of PTPRE suppresses tumor progression and improves sorafenib response in hepatocellular carcinoma.
Hippo/YAP1 promotes osteoporotic mice bone defect repair via the activating of Wnt signaling pathway.
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Genetic interactions reveal distinct biological and therapeutic implications in breast cancer.
A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis.
ELP3 stabilizes c-Myc to promote tumorigenesis.
Melatonin inhibits tongue squamous cell carcinoma: Interplay of ER stress-induced apoptosis and autophagy with cell migration.
Glutamine Promotes Porcine Intestinal Epithelial Cell Proliferation through the Wnt/β-Catenin Pathway.
DCDC2 inhibits hepatic stellate cell activation and ameliorates CCl(4)-induced liver fibrosis by suppressing Wnt/β-catenin signaling.
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression.
A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice.
Single-cell and Spatial Transcriptomics Identified Fatty Acid-binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension.
Novel BRD4-p53 Inhibitor SDU-071 Suppresses Proliferation and Migration of MDA-MB-231 Triple-Negative Breast Cancer Cells.
Hawthorn Proanthocyanidin Extract Inhibits Colorectal Carcinoma Metastasis by Targeting the Epithelial-Mesenchymal Transition Process and Wnt/β-Catenin Signaling Pathway.
Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma.
ASPM overexpression enhances cellular proliferation and migration and predicts worse prognosis for papillary renal cell carcinoma.
GPC3 Promotes Lung Squamous Cell Carcinoma Progression and HLA-A2-Restricted GPC3 Antigenic Peptide-Modified Dendritic Cell-Induced Cytotoxic T Lymphocytes to Kill Lung Squamous Cell Carcinoma Cells.
Parkin increases the risk of colitis by downregulation of VDR via autophagy-lysosome degradation.
FAK downregulation suppresses stem-like properties and migration of human colorectal cancer cells.
UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway.
Esomeprazole Alleviates Cisplatin Resistance by Inhibiting the AKT/mTOR Pathway in Ovarian Cancer Cells.
Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells.
Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study.
UBE2S targets RPL26 for ubiquitination and degradation to promote non-small cell lung cancer progression via regulating c-Myc.
Onvansertib inhibits the proliferation and improves the cisplatin-resistance of lung adenocarcinoma via β-catenin/c-Myc signaling pathway.
E3 ubiquitin ligase TRIM21 targets TIF1γ to regulate β-catenin signaling in glioblastoma.
RNA N6-methyladenosine reader IGF2BP3 promotes acute myeloid leukemia progression by controlling stabilization of EPOR mRNA.
Increased α-HB links colorectal cancer and diabetes by potentiating NF-κB signaling.
Identification of a diketopiperazine-based O-GlcNAc transferase inhibitor sensitizing hepatocellular carcinoma to CDK9 inhibition.
Loss of NSUN6 inhibits osteosarcoma progression by downregulating EEF1A2 expression and activation of Akt/mTOR signaling pathway via m(5)C methylation.
SNTB1 regulates colorectal cancer cell proliferation and metastasis through YAP1 and the WNT/β-catenin pathway.
Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling.
Nucleolar HEAT Repeat Containing 1 Up-regulated by the Mechanistic Target of Rapamycin Complex 1 Signaling Promotes Hepatocellular Carcinoma Growth by Dominating Ribosome Biogenesis and Proteome Homeostasis.
Ginsenoside Rh4 delays skeletal muscle aging through SIRT1 pathway.
CCDC85C suppresses colorectal cancer cells proliferation and metastasis through activating GSK-3β and promoting β-catenin degradation.
Triiodothyronine positively regulates endoplasmic reticulum-associated degradation (ERAD) and promotes androgenic signaling in androgen-dependent prostate cancer cells.
Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC.
Oridonin inhibits the occurrence and development of colorectal cancer by reversing the Warburg effect via reducing PKM2 dimer formation and preventing its entry into the nucleus.
ALDOC promotes non-small cell lung cancer through affecting MYC-mediated UBE2N transcription and regulating Wnt/β-catenin pathway.
ESRRB Inhibits the TGFβ Signaling Pathway to Drive Cell Proliferation in Cervical Cancer.
MDIG-mediated H3K9me3 demethylation upregulates Myc by activating OTX2 and facilitates liver regeneration.
Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1.
DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway.
Knockdown of LINC00702 inhibits the growth and induces apoptosis of breast cancer through the Wnt/β-catenin pathway.
Abnormal expression of CEBPB promotes the progression of renal cell carcinoma through regulating the generation of IL-6.
ANKRD22 knockdown suppresses papillary thyroid cell carcinoma growth and migration and modulates the Wnt/β-catenin signaling pathway.
Discovery of an Heparin-Binding Epidermal Growth Factor Domain Antibody from a Phage Library and Analysis of Its Inhibitory Effects in SKOV3 Cells.
HBV precore G1896A mutation promotes growth of hepatocellular carcinoma cells by activating ERK/MAPK pathway.
IGF2BP2 promotes ovarian cancer growth and metastasis by upregulating CKAP2L protein expression in an m(6) A-dependent manner.
Upregulation of SOX9 promotes the self-renewal and tumorigenicity of cervical cancer through activating the Wnt/β-catenin signaling pathway.
LncRNA BCAN-AS1 stabilizes c-Myc via N(6)-methyladenosine-mediated binding with SNIP1 to promote pancreatic cancer.
RRM2‑mediated Wnt/β‑catenin signaling pathway activation in lung adenocarcinoma: A potential prognostic biomarker.
Proliferation-associated 2G4 P48 is stabilized by malignant T-cell amplified sequence 1 and promotes the proliferation of head and neck squamous cell carcinoma.
Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer.
Elucidating the pharmacological effects of Compound Kushen injection on MYC-P15-CCND1 signaling pathway in nasopharyngeal carcinoma - An in vitro study.
HHV-6A Infection of Papillary Thyroid Cancer Cells Induces Several Effects Related to Cancer Progression.
Novel c-Myc G4 stabilizer EP12 promotes myeloma cytotoxicity by disturbing NF-κB signaling.
Baicalein Attenuates Neuroinflammation in LPS-Treated BV-2 Cells by Inhibiting Glycolysis via STAT3/c-Myc Pathway.
O-GlcNAc has crosstalk with ADP-ribosylation via PARG.
Hsa_circ_0001479 accelerates tumorigenesis of gastric cancer and mediates immune escape.
HSP110 Inhibition in Primary Effusion Lymphoma Cells: One Molecule, Many Pro-Survival Targets.
m6A modified BACE1-AS contributes to liver metastasis and stemness-like properties in colorectal cancer through TUFT1 dependent activation of Wnt signaling.
The role of an amphiphilic helix and transmembrane region in the efficient acylation of the M2 protein from influenza virus.
SHFM1 deficiency suppresses esophageal squamous cell carcinomas progression via modulating NF‑κB signaling and enhancing nature killer cell‑mediated tumor surveillance.
DNMT3A R882H mutation promotes acute leukemic cell survival by regulating glycolysis through the NRF2/NQO1 axis.
NCBP1 enhanced proliferation of DLBCL cells via METTL3-mediated m6A modification of c-Myc.
Guanine nucleotide exchange factor T exerts the cancer-promoting function in cholangiocarcinoma by enhancing the Wnt-GSK-3β-β-catenin cascade via regulation of Rac1/Cdc42.
PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression.
Decreasing expression of Prohibitin-2 lowers the oncogenicity of renal cell carcinoma cells by suppressing eIF4E-mediated oncogene translation via MNK inhibition.
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling.
CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis.
1,25(OH)(2) D(3) induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.
Oncogenes and Methionine Addiction of Cancer: Role of c-MYC.
JQ-1/bortezomib combination strongly impairs MM and PEL survival by inhibiting c-Myc and mTOR despite the activation of prosurvival mechanisms.
Ursolic Acid Suppresses Colorectal Cancer by Down-Regulation of Wnt/β-Catenin Signaling Pathway Activity.
A novel feedback regulated loop of circRRM2-IGF2BP1-MYC promotes breast cancer metastasis.
The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice.
Discovery of Potent DYRK2 Inhibitors with High Selectivity, Great Solubility, and Excellent Safety Properties for the Treatment of Prostate Cancer.
A novel selective estrogen receptor degrader induces cell cycle arrest in breast cancer via ERα degradation and the autophagy-lysosome pathway.
Gold nanoparticles inhibit tumor growth via targeting the Warburg effect in a c-Myc-dependent way.
Dishevelled segment polarity protein 2 promotes gastric cancer progression through Wnt/β-catenin pathway.
Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells.
Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling.
METTL3-dependent m(6)A methylation facilitates uterine receptivity and female fertility via balancing estrogen and progesterone signaling.
SOX1 acts as a tumor hypnotist rendering nasopharyngeal carcinoma cells refractory to chemotherapy.
HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.
Targeting SMYD2 inhibits prostate cancer cell growth by regulating c-Myc signaling.
eIF3a sustains non-small cell lung cancer stem cell-like properties by promoting YY1-mediated transcriptional activation of β-catenin.
Patch-clamp studies and cell viability assays suggest a distinct site for viroporin inhibitors on the E protein of SARS-CoV-2.
Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness.
Hypoxia-cleavable and specific targeted nanomedicine delivers epigenetic drugs for enhanced treatment of breast cancer and bone metastasis.
RNF106 aggravates esophageal squamous cell carcinoma progression through LATS2/YAP axis.
Targeting CDK12 obviates the malignant phenotypes of colorectal cancer through the Wnt/β-catenin signaling pathway.
Stat3 shRNA delivery with folate receptor-modified multi-functionalized graphene oxide particles for combined infrared radiation and gene therapy in hepatocellular carcinoma.
CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1.
Ubiquitin-specific peptidase 14 maintains estrogen receptor α stability via its deubiquitination activity in endometrial cancer.
Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease.
Dietary selenium excess affected spermatogenesis via DNA damage and telomere-related cell senescence and apoptosis in mice.
Pattern recognition receptor mediated innate immune response requires a Rif-dependent pathway.
Immune responses of hemocytes in the blood clam Tegillarca granosa in response to in vivo Vibrio harveyi infection.
Molecular Mechanism of Adenovirus Late Protein L4-100K Chaperones the Trimerization of Hexon.
USP39 stabilizes β-catenin by deubiquitination and suppressing E3 ligase TRIM26 pre-mRNA maturation to promote HCC progression.
B7-H6 enhances F-actin rearrangement by targeting c-MYC activation to promote medulloblastoma migration and invasion.
Targeting Tumor Hypoxia Inhibits Aggressive Phenotype of Dedifferentiated Thyroid Cancer.
Bisphenol A and Di(2-Ethylhexyl) Phthalate promote pulmonary carcinoma in female rats via estrogen receptor beta: In vivo and in silico analysis.
CJ(2): A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane.
Myc-mediated circular RNA circMcph1/miR-370-3p/Irak2 axis is a progressive regulator in hepatic fibrosis.
Identification of non-coding RNAs and their functional network associated with optic nerve invasion in retinoblastoma.
CRISPR-Cas9-Mediated NPC1 Gene Deletion Enhances HEK 293 T Cell Adhesion by Regulating E-Cadherin.
POR overexpression induces tamoxifen-resistance in breast cancer through the STAT1/c-Myc pathway.
MiR-138-5p suppresses the progression of lung cancer by targeting SNIP1.
Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia.
Resveratrol suppresses lung cancer by targeting cancer stem-like cells and regulating tumor microenvironment.
The Prognostic Value and the Oncogenic and Immunological Roles of Vacuolar Protein Sorting Associated Protein 26 A in Pancreatic Adenocarcinoma.
A program of successive gene expression in mouse one-cell embryos.
Caprin-1 plays a role in cell proliferation and Warburg metabolism of esophageal carcinoma by regulating METTL3 and WTAP.
LncGMDS-AS1 promotes the tumorigenesis of colorectal cancer through HuR-STAT3/Wnt axis.
mcPGK1-dependent mitochondrial import of PGK1 promotes metabolic reprogramming and self-renewal of liver TICs.
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
Luteoloside Induces G0/G1 Phase Arrest of Neuroblastoma Cells by Targeting p38 MAPK.
Tripartite motif containing 33 demonstrated anticancer effect by degrading c‑Myc: Limitation of glutamine metabolism and proliferation in endometrial carcinoma cells.
Classical swine fever virus NS5A protein antagonizes innate immune response by inhibiting the NF-κB signaling.
The Combination of Methioninase and Ethionine Exploits Methionine Addiction to Selectively Eradicate Osteosarcoma Cells and Not Normal Cells and Synergistically Down-regulates the Expression of C-MYC.
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
Design, synthesis, and biological evaluation of novel 4,4'-bipyridine derivatives acting as CDK9-Cyclin T1 protein-protein interaction inhibitors against triple-negative breast cancer.
RNA-binding motif protein 10 inactivates c-Myc by partnering with ribosomal proteins uL18 and uL5.
ESM1 Interacts with c-Met to Promote Gastric Cancer Peritoneal Metastasis by Inducing Angiogenesis.
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stability.
AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer.
Hydrogel-based miR-192 delivery inhibits the development of hepatocellular carcinoma by suppressing the GSK3β/Wnt/β-catenin pathway.
NDRG3 regulates imatinib resistance by promoting β‑catenin accumulation in the nucleus in chronic myelogenous leukemia.
USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.
Phosphorylated PTTG1 switches its subcellular distribution and promotes β-catenin stabilization and subsequent transcription activity.
PPARγ agonist inhibits c-Myc-mediated colorectal cancer tumor immune escape.
221S-1a inhibits endothelial proliferation in pathological angiogenesis through ERK/c-Myc signaling.
Histone acetylation by HBO1 (KAT7) activates Wnt/β-catenin signaling to promote leukemogenesis in B-cell acute lymphoblastic leukemia.
SUMOylation of SMAD4 by PIAS1 in Conjunction with Vimentin Upregulation Promotes Migration Potential in Non-Small Cell Lung Cancer.
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
CD58 acts as a tumor promotor in hepatocellular carcinoma via activating the AKT/GSK-3β/β-catenin pathway.
Deletion of the tyrosine phosphatase Shp2 in cervical cancer cells promotes reprogramming of glutamine metabolism.
Exosomes incorporated with black phosphorus quantum dots attenuate retinal angiogenesis via disrupting glucose metabolism.
[High expression of MYH9 inhibits apoptosis of non-small cell lung cancer cells through activating the AKT/c-Myc pathway].
Hyperthermia inhibits growth of nasopharyngeal carcinoma through degradation of c-Myc.
Ubiquitination and degradation of MGMT by TRIM72 increases the sensitivity of uveal melanoma cells to Dacarbazine treatment.
PHGDH Inhibitor CBR-5884 Inhibits Epithelial Ovarian Cancer Progression via ROS/Wnt/β-Catenin Pathway and Plays a Synergistic Role with PARP Inhibitor Olaparib.
Total Saponins of Radix Clematis Regulate Fibroblast-Like Synoviocyte Proliferation in Rheumatoid Arthritis via the LncRNA OIP5-AS1/MiR-410-3p/Wnt7b Signaling Pathway.
ATF4/MYC Regulates MTHFD2 to Promote NSCLC Progression by Mediating Redox Homeostasis.
Resveratrol Downregulates miR-155-5p to Block the Malignant Behavior of Gastric Cancer Cells.
Fufang Xueshuantong Improves Diabetic Cardiomyopathy by Regulating the Wnt/β-Catenin Pathway.
FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A.
Intervention Mechanism of Hunag-Lian Jie-Du Decoction on Canonical Wnt/β-Catenin Signaling Pathway in Psoriasis Mouse Model.
Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.
Therapeutical Significance of Serpina3n Subsequent Cerebral Ischemia via Cytotoxic Granzyme B Inactivation.
HERC3 directly targets RPL23A for ubiquitination degradation and further regulates Colorectal Cancer proliferation and the cell cycle.
HJURP Promotes Malignant Progression and Mediates Sensitivity to Cisplatin and WEE1-inhibitor in Serous Ovarian Cancer.
TBL1X and Flot2 form a positive feedback loop to promote metastasis in nasopharyngeal carcinoma.
GALNT1 Enhances Malignant Phenotype of Gastric Cancer via Modulating CD44 Glycosylation to Activate the Wnt/β-catenin Signaling Pathway.
CCDC65, a Gene Knockout that leads to Early Death of Mice, acts as a potentially Novel Tumor Suppressor in Lung Adenocarcinoma.
CSTF2 Acts as a Prognostic Marker Correlated with Immune Infiltration in Hepatocellular Carcinoma.
Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer.
EST12 regulates Myc expression and enhances anti-mycobacterial inflammatory response via RACK1-JNK-AP1-Myc immune pathway.
Norcantharidin overcomes vemurafenib resistance in melanoma by inhibiting pentose phosphate pathway and lipogenesis via downregulating the mTOR pathway.
Matrine, a potential c-Myc inhibitor, suppresses ribosome biogenesis and nucleotide metabolism in myeloid leukemia.
A novel HCC prognosis predictor PDSS1 affects the cell cycle through the STAT3 signaling pathway in HCC.
Overexpression of SFXN1 indicates poor prognosis and promotes tumor progression in lung adenocarcinoma.
Vitamin D receptor enhances NLRC4 inflammasome activation by promoting NAIPs-NLRC4 association.
MARCH1 promotes the growth and maintaining of stem cell-like characteristics of gastric cancer cells by activating the Wnt/β-catenin signaling pathway.
PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop.
Identification of Trovafloxacin, Ozanimod, and Ozenoxacin as Potent c-Myc G-Quadruplex Stabilizers to Suppress c-Myc Transcription and Myeloma Growth.
The HN1/HMGB1 axis promotes the proliferation and metastasis of hepatocellular carcinoma and attenuates the chemosensitivity to oxaliplatin.
tRNA-m(1)A modification promotes T cell expansion via efficient MYC protein synthesis.
Skin chronological aging drives age-related bone loss via secretion of cystatin-A.
Structure-based discovery of Licoflavone B and Ginkgetin targeting c-Myc G-quadruplex to suppress c-Myc transcription and myeloma growth.
c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway.
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway.
RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway.
Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma.
Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting β-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis.
Babao Dan Alleviates 5-Fluorouracil-Induced Intestinal Damage via Wnt/β-Catenin Pathway.
USP17L2-SIRT7 axis regulates DNA damage repair and chemoresistance in breast cancer cells.
A dynamic fluorescence probed glycolysis suppression process in HeLa cells treated with trichostatin A.
Cross-regulome profiling of RNA polymerases highlights the regulatory role of polymerase III on mRNA transcription by maintaining local chromatin architecture.
Amination Potentially Augments the Ameliorative Effect of Curcumin on Inhibition of the IL-6/Stat3/c-Myc Pathway and Gut Microbial Modulation in Colitis-Associated Tumorigenesis.
PSMA1 mediates tumor progression and poor prognosis of gastric carcinoma by deubiquitinating and stabilizing TAZ.
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway.
G protein subunit gamma 5 promotes the proliferation, metastasis and glycolysis of breast cancer cells through the Wnt/β-catenin pathway.
Bufalin Inhibits Tumorigenesis, Stemness, and Epithelial-Mesenchymal Transition in Colorectal Cancer through a C-Kit/Slug Signaling Axis.
SiNiSan alleviates liver injury by promoting hepatic stem cell differentiation via Wnt/β-catenin signaling pathway.
Jumonji-C domain-containing protein 5 suppresses proliferation and aerobic glycolysis in pancreatic cancer cells in a c-Myc-dependent manner.
Heterozygote loss-of-function variants in the LRP5 gene cause familial exudative vitreoretinopathy.
Guanylate-binding Protein 2 Expression Is Associated With Poor Survival and Malignancy in Clear-cell Renal Cell Carcinoma.
Therapeutic targeting of the mevalonate-geranylgeranyl diphosphate pathway with statins overcomes chemotherapy resistance in small cell lung cancer.
Venetoclax enhances DNA damage induced by XPO1 inhibitors: A novel mechanism underlying the synergistic antileukaemic effect in acute myeloid leukaemia.
Urea transporter B downregulates polyamines levels in melanoma B16 cells via p53 activation.
FL118, acting as a 'molecular glue degrader', binds to dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c-Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy.
Mitochondrial GCN5L1 regulates glutaminase acetylation and hepatocellular carcinoma.
CYP2E1 plays a suppressive role in hepatocellular carcinoma by regulating Wnt/Dvl2/β-catenin signaling.
Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability.
UHMK1 aids colorectal cancer cell proliferation and chemoresistance through augmenting IL-6/STAT3 signaling.
Infectious Bronchitis Virus Nsp14 Degrades JAK1 to Inhibit the JAK-STAT Signaling Pathway in HD11 Cells.
O-GlcNAc modification mediates aquaporin 3 to coordinate endometrial cell glycolysis and affects embryo implantation.
lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus.
DECR1 directly activates HSL to promote lipolysis in cervical cancer cells.
A novel mechanism of the lncRNA PTTG3P/miR-142-5p/JAG1 axis modulating tongue cancer cell phenotypes through the Notch1 signaling.
Bisphenol A drives di(2-ethylhexyl) phthalate promoting thyroid tumorigenesis via regulating HDAC6/PTEN and c-MYC signaling.
Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma Cells.
SP2509, a Selective Inhibitor of LSD1, Suppresses Retinoblastoma Growth by Downregulating β-catenin Signaling.
Inhibition of STAT3(Y705) phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells.
CircTCF25 serves as a sponge for miR-206 to support proliferation, migration, and invasion of glioma via the Jak2/p-Stat3/CypB axis.
c-MYC and HIF1α promoter G-quadruplexes dependent metabolic regulation mechanism of berberine in colon cancer.
N-methyl-D-aspartate receptor blockers attenuate bleomycin-induced pulmonary fibrosis by inhibiting endogenous mesenchymal stem cells senescence.
Paired box 8 facilitates the c-MYC related cell cycle progress in TP53-mutation uterine corpus endometrial carcinoma through interaction with DDX5.
Synthesis and structure-activity relationship study of a potent MHO7 analogue as potential anti-triple negative breast cancer agent.
Metformin abrogates pathological TNF-α-producing B cells through mTOR-dependent metabolic reprogramming in polycystic ovary syndrome.
TET2-BCLAF1 transcription repression complex epigenetically regulates the expression of colorectal cancer gene Ascl2 via methylation of its promoter.
Photoaffinity Labeling-Based Chemoproteomic Strategy Reveals RBBP4 as a Cellular Target of Protopanaxadiol against Colorectal Cancer Cells.
miR-3682-3p directly targets FOXO3 and stimulates tumor stemness in hepatocellular carcinoma via a positive feedback loop involving FOXO3/PI3K/AKT/c-Myc.
Ginsenoside Rh4 Suppresses Metastasis of Esophageal Cancer and Expression of c-Myc via Targeting the Wnt/β-Catenin Signaling Pathway.
CTNND1 variants cause familial exudative vitreoretinopathy through the Wnt/cadherin axis.
Forkhead Box S1 mediates epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway to regulate colorectal cancer progression.
c-myc-mediated upregulation of NAT10 facilitates tumor development via cell cycle regulation in non-small cell lung cancer.
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells.
DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and Kaposi sarcoma herpesvirus replication.
Luteolin alleviates ischemia/reperfusion injury-induced no-reflow by regulating Wnt/β-catenin signaling in rats.
c-Myc Targets HDAC3 to Suppress NKG2DL Expression and Innate Immune Response in N-Type SCLC through Histone Deacetylation.
Integrating network pharmacology deciphers the action mechanism of Zuojin capsule in suppressing colorectal cancer.
Estrogen receptor beta increases clear cell renal cell carcinoma stem cell phenotype via altering the circPHACTR4/miR-34b-5p/c-Myc signaling.
CDK14/β-catenin/TCF4/miR-26b positive feedback regulation modulating pancreatic cancer cell phenotypes in vitro and tumor growth in mice model in vivo.
l-Argine regulates the proliferation, apoptosis and endocrine activity by alleviating oxidative stress in sheep endometrial epithelial cells.
Myocardin/microRNA-30a/Beclin1 signaling controls the phenotypic modulation of vascular smooth muscle cells by regulating autophagy.
The miR-34a/WNT7B modulates the sensitivity of cholangiocarcinoma cells to p53-mediated photodynamic therapy toxicity.
The anti-MDR efficacy of YAN against A549/Taxol cells is associated with its inhibition on glycolysis and is further enhanced by 2-deoxy-d-glucose.
Circular RNA circSHPRH inhibits the malignant behaviors of bladder cancer by regulating the miR-942/BARX2 pathway.
Programmed death-ligand 1 signaling and expression are reversible by lycopene via PI3K/AKT and Raf/MEK/ERK pathways in tongue squamous cell carcinoma.
Blockade of Nuclear β-Catenin Signaling via Direct Targeting of RanBP3 with NU2058 Induces Cell Senescence to Suppress Colorectal Tumorigenesis.
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Long non-coding RNA CTSLP8 mediates ovarian cancer progression and chemotherapy resistance by modulating cellular glycolysis and regulating c-Myc expression through PKM2.
Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity.
CircP50 functions through the phosphorylation- and acetylation-activated p53 pathway to mediate inorganic arsenic-induced apoptosis in A549 cells.
Low expression of MYCN promotes cisplatin resistance by suppressing cisplatin-induced apoptosis in epithelial ovarian cancer.
USF1-CHCHD4 axis promotes lung adenocarcinoma progression partially via activating the MYC pathway.
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
SMAD4 Loss Induces c-MYC-Mediated NLE1 Upregulation to Support Protein Biosynthesis, Colorectal Cancer Growth, and Metastasis.
Unraveling the toxic effects mediated by the neurodegenerative disease-associated S375G mutation of TDP-43 and its S375E phosphomimetic variant.
NSUN2-mediated RNA m(5)C modification modulates uveal melanoma cell proliferation and migration.
Phosphorylated STYK1 restrains the inhibitory role of EGFR in autophagy initiation and EGFR-TKIs sensitivity.
Molecular cloning, characterization, and tissue distribution of c-Myc from blood clam Tegillarca granosa and its role in cadmium-induced stress response.
Alpha-linolenic acid inhibits hepatocellular carcinoma cell growth through Farnesoid X receptor/β-catenin signaling pathway.
Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas.
c-Abl kinase-mediated phosphorylation of γ-tubulin promotes γ-tubulin ring complexes assembly and microtubule nucleation.
USP19 (ubiquitin specific peptidase 19) promotes TBK1 (TANK-binding kinase 1) degradation via chaperone-mediated autophagy.
HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC.
Mitochondrial fragmentation is crucial for c-Myc-driven hepatoblastoma-like liver tumors.
RNF8 up-regulates AR/ARV7 action to contribute to advanced prostate cancer progression.
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction.
IL-18-Mediated SLC7A5 Overexpression Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells via the c-MYC Pathway.
CircGNG4 Promotes the Progression of Prostate Cancer by Sponging miR-223 to Enhance EYA3/c-myc Expression.
SP1-Mediated Upregulation of Long Noncoding RNA ZFAS1 Involved in Non-syndromic Cleft Lip and Palate via Inactivating WNT/β-Catenin Signaling Pathway.
Blockage of Extracellular Signal-Regulated Kinase Exerts an Antitumor Effect via Regulating Energy Metabolism and Enhances the Efficacy of Autophagy Inhibitors by Regulating Transcription Factor EB Nuclear Translocation in Osteosarcoma.
CORO6 Promotes Cell Growth and Invasion of Clear Cell Renal Cell Carcinoma via Activation of WNT Signaling.
Kochia scoparia Saponin Momordin Ic Modulates HaCaT Cell Proliferation and Apoptosis via the Wnt/β-Catenin Pathway.
Effects of MicroRNA-195-5p on Biological Behaviors and Radiosensitivity of Lung Adenocarcinoma Cells via Targeting HOXA10.
NEK2 plays an active role in Tumorigenesis and Tumor Microenvironment in Non-Small Cell Lung Cancer.
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
TRIM11 Promotes Proliferation, Migration, Invasion and EMT of Gastric Cancer by Activating β-Catenin Signaling.
Novel lncRNA LINC01614 Facilitates Bladder Cancer Proliferation, Migration and Invasion Through the miR-217/RUNX2/Wnt/β-Catenin Axis.
Coronin 6 promotes hepatocellular carcinoma progression by enhancing canonical Wnt/beta-catenin signaling pathway.
LncRNA MALAT1 was regulated by HPV16 E7 independently of pRB in cervical cancer cells.
c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.
SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.
Therapeutic Potential of CUDC-907 (Fimepinostat) for Hepatocarcinoma Treatment Revealed by Tumor Spheroids-Based Drug Screening.
YY1-mediated reticulocalbin-2 upregulation promotes the hepatocellular carcinoma progression via activating MYC signaling.
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
tRNA-Derived Fragment tRF-Glu-TTC-027 Regulates the Progression of Gastric Carcinoma via MAPK Signaling Pathway.
Oleic Acid and Insulin as Key Characteristics of T2D Promote Colorectal Cancer Deterioration in Xenograft Mice Revealed by Functional Metabolomics.
A Novel Mechanism of the c-Myc/NEAT1 Axis Mediating Colorectal Cancer Cell Response to Photodynamic Therapy Treatment.
MiR-338-5p Inhibits EGF-Induced EMT in Pancreatic Cancer Cells by Targeting EGFR/ERK Signaling.
Paired-like homeodomain transcription factor 2 affects endometrial cell function and embryo implantation through the Wnt/β-catenin pathway.
Expression of TCF3 in Wilms' tumor and its regulatory role in kidney tumor cell viability, migration and apoptosis in vitro.
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
PHLDA3 exerts an antitumor function in prostate cancer by down-regulating Wnt/β-catenin pathway via inhibition of Akt.
Bromodomain-containing protein 9 promotes hepatocellular carcinoma progression via activating the Wnt/β-catenin signaling pathway.
Co-exposure to BPA and DEHP enhances susceptibility of mammary tumors via up-regulating Esr1/HDAC6 pathway in female rats.
Clusterin inhibits Cr(VI)-induced apoptosis via enhancing mitochondrial biogenesis through AKT-associated STAT3 activation in L02 hepatocytes.
LPCAT1 reprogramming cholesterol metabolism promotes the progression of esophageal squamous cell carcinoma.
LGR6 activates the Wnt/β-catenin signaling pathway and forms a β-catenin/TCF7L2/LGR6 feedback loop in LGR6(high) cervical cancer stem cells.
ASPM promotes hepatocellular carcinoma progression by activating Wnt/β-catenin signaling through antagonizing autophagy-mediated Dvl2 degradation.
The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation.
Cancer cell immune mimicry delineates onco-immunologic modulation.
RCN1 induces sorafenib resistance and malignancy in hepatocellular carcinoma by activating c-MYC signaling via the IRE1α-XBP1s pathway.
An SETD1A/Wnt/β-catenin feedback loop promotes NSCLC development.
GRIM-19 inhibits proliferation and induces apoptosis in a p53-dependent manner in colorectal cancer cells through the SIRT7/PCAF/MDM2 axis.
The ER membrane protein complex subunit Emc3 controls angiogenesis via the FZD4/WNT signaling axis.
Babao Dan is a robust anti-tumor agent via inhibiting wnt/β-catenin activation and cancer cell stemness.
The parent-of-origin lncRNA MISSEN regulates rice endosperm development.
Model-based analysis uncovers mutations altering autophagy selectivity in human cancer.
ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling.
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
Apatinib suppresses lung cancer stem-like cells by complex interplay between β-catenin signaling and mitochondrial ROS accumulation.
SHARPIN stabilizes β-catenin through a linear ubiquitination-independent manner to support gastric tumorigenesis.
LncRNA NBR2 aggravates hepatoblastoma cell malignancy and promotes cell proliferation under glucose starvation through the miR-22/TCF7 axis.
The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation.
FAM122A promotes acute myeloid leukemia cell growth through inhibiting PP2A activity and sustaining MYC expression.
Salidroside overcomes dexamethasone resistance in T-acute lymphoblastic leukemia cells.
Exosomal SNHG16 secreted by CSCs promotes glioma development via TLR7.
The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC.
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
MMP12 is a potential therapeutic target for Adamantinomatous craniopharyngioma: Conclusions from bioinformatics analysis and in vitro experiments.
WRKY9 transcription factor regulates cytochrome P450 genes CYP94B3 and CYP86B1, leading to increased root suberin and salt tolerance in Arabidopsis.
A Novel Long Non-Coding RNA lnc030 Maintains Breast Cancer Stem Cell Stemness by Stabilizing SQLE mRNA and Increasing Cholesterol Synthesis.
miR-937-5p targets SOX17 to modulate breast cancer cell cycle and cell proliferation through the Wnt signaling pathway.
Mutant TP53 interacts with BCAR1 to contribute to cancer cell invasion.
TRIP13 promotes the proliferation and invasion of lung cancer cells via the Wnt signaling pathway and epithelial-mesenchymal transition.
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
The effects of histone crotonylation and bromodomain protein 4 on prostate cancer cell lines.
Cholesterol activates the Wnt/PCP-YAP signaling in SOAT1-targeted treatment of colon cancer.
OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase.
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
MEG3/MIR-376B-3P/HMGA2 axis is involved in pituitary tumor invasiveness.
Compound Kushen Injection intervenes metabolic reprogramming and epithelial-mesenchymal transition of HCC via regulating β-catenin/c-Myc signaling.
Simiao Qingwen Baidu decoction inhibits Epstein-Barr virus-induced B lymphoproliferative disease and lytic viral replication.
Development of a novel anti-liver fibrosis formula with luteolin, licochalcone A, aloe-emodin and acacetin by network pharmacology and transcriptomics analysis.
O-GlcNAc modified-TIP60/KAT5 is required for PCK1 deficiency-induced HCC metastasis.
Long non-coding RNA KRT8P41/miR-193a-3p/FUBP1 axis modulates the proliferation and invasion of chordoma cells.
The endocytic pathway of Pt nanoclusters and their induced apoptosis of A549 and A549/Cis cells through c-Myc/p53 and Bcl-2/caspase-3 signaling pathways.
MiR-130a-3p suppresses colorectal cancer growth by targeting Wnt Family Member 1 (WNT1).
Roles of WNT6 in Sheep Endometrial Epithelial Cell Cycle Progression and Uterine Glands Organogenesis.
Efferocytosis induces macrophage proliferation to help resolve tissue injury.
hsa_circ_0068631 promotes breast cancer progression through c-Myc by binding to EIF4A3.
CCT8 recovers WTp53-suppressed cell cycle evolution and EMT to promote colorectal cancer progression.
miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling.
Long non-coding RNA RP5-821D11.7 promotes proliferation, migration, and epithelial-mesenchymal transition in glioma and glioma stem-like cells.
Cyclophilin acts as a ribosome biogenesis factor by chaperoning the ribosomal protein (PlRPS15) in filamentous fungi.
LncRNA MIR155HG Promotes Temozolomide Resistance by Activating the Wnt/β-Catenin Pathway Via Binding to PTBP1 in Glioma.
The novel interaction mode among centromere sub-complex CENP-O/P/U/Q/R.
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
N(6) -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness.
PD-L1 lncRNA splice isoform promotes lung adenocarcinoma progression via enhancing c-Myc activity.
MFN2 interacts with nuage-associated proteins and is essential for male germ cell development by controlling mRNA fate during spermatogenesis.
Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.
THAP11 Functions as a Tumor Suppressor in Gastric Cancer through Regulating c-Myc Signaling Pathways.
Ginsenoside Rg1 Improves Differentiation by Inhibiting Senescence of Human Bone Marrow Mesenchymal Stem Cell via GSK-3β and β-Catenin.
ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p.
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway.
Identification of a Novel c-Myc Inhibitor 7594-0037 by Structure-Based Virtual Screening and Investigation of Its Anti-Cancer Effect on Multiple Myeloma.
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Combination of Inositol Hexaphosphate and Inositol Inhibits Liver Metastasis of Colorectal Cancer in Mice Through the Wnt/β-Catenin Pathway.
Antitumor Effect of miR-1294/Pyruvate Kinase M2 Signaling Cascade in Osteosarcoma Cells.
DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway.
Simultaneous Inhibition of Ornithine Decarboxylase 1 and Pyruvate Kinase M2 Exerts Synergistic Effects Against Hepatocellular Carcinoma Cells.
Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.
Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features.
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
The M6A methyltransferase METTL3 promotes the development and progression of prostate carcinoma via mediating MYC methylation.
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
LncRNA CSMD1-1 promotes the progression of Hepatocellular Carcinoma by activating MYC signaling.
Overexpression of miRNA-3613-3p Enhances the Sensitivity of Triple Negative Breast Cancer to CDK4/6 Inhibitor Palbociclib.
Long Non-coding RNA CCAT1 Acts as an Oncogene and Promotes Sunitinib Resistance in Renal Cell Carcinoma.
USP9X promotes the proliferation, invasion and metastasis of liver cancer cells through regulating the JAK2/STAT3 signaling.
Synthesis, docking studies and antitumor activity of phenanthroimidazole derivatives as promising c-myc G-quadruplex DNA stabilizers.
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
Long non-coding RNA LPP-AS2 promotes glioma tumorigenesis via miR-7-5p/EGFR/PI3K/AKT/c-MYC feedback loop.
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
sATP‑binding cassette subfamily G member 2 enhances the multidrug resistance properties of human nasal natural killer/T cell lymphoma side population cells.
Let-7b downgrades CCND1 to repress osteogenic proliferation and differentiation of MC3T3-E1 cells: An implication in osteoporosis.
Fatty acid synthase contributes to epithelial-mesenchymal transition and invasion of salivary adenoid cystic carcinoma through PRRX1/Wnt/β-catenin pathway.
STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.
Cancer-associated fibroblasts-derived exosomal miR-17-5p promotes colorectal cancer aggressive phenotype by initiating a RUNX3/MYC/TGF-β1 positive feedback loop.
JARID1B promotes colorectal cancer proliferation and Wnt/β-catenin signaling via decreasing CDX2 level.
Redox-responsive nanoplatform for codelivery of miR-519c and gemcitabine for pancreatic cancer therapy.
USP22 positively modulates ERα action via its deubiquitinase activity in breast cancer.
MSCs reduce airway remodeling in the lungs of asthmatic rats through the Wnt/β-catenin signaling pathway.
Tumor-like features of gene expression and metabolic profiles in enlarged pancreatic islets are associated with impaired incretin-induced insulin secretion in obese diabetes: A study of Zucker fatty diabetes mellitus rat.
Long noncoding RNA CMPK2 promotes colorectal cancer progression by activating the FUBP3-c-Myc axis.
The miRNA-149-5p/MyD88 axis is responsible for ursolic acid-mediated attenuation of the stemness and chemoresistance of non-small cell lung cancer cells.
Lipid rafts are required for effective renal D(1) dopamine receptor function.
BMX activates Wnt/β-catenin signaling pathway to promote cell proliferation and migration in breast cancer.
ALDH1A1 maintains the cancer stem-like cells properties of esophageal squamous cell carcinoma by activating the AKT signal pathway and interacting with β-catenin.
SOX1 promotes differentiation of nasopharyngeal carcinoma cells by activating retinoid metabolic pathway.
Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep.
Inhibition of miR-9 decreases osteosarcoma cell proliferation.
δ-Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β-catenin nuclear localization and activating its downstream target genes.
MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B.
Auxiliary antitumor effects of fungal proteins from Hericium erinaceus by target on the gut microbiota.
RIC-seq for global in situ profiling of RNA-RNA spatial interactions.
The role of miR-21/RECK in the inhibition of osteosarcoma by curcumin.
Effects of cisplatin on the proliferation, invasion and apoptosis of breast cancer cells following β‑catenin silencing.
Endogenous thrombopoietin promotes non-small-cell lung carcinoma cell proliferation and migration by regulating EGFR signalling.
Activator of thyroid and retinoid receptor increases sorafenib resistance in hepatocellular carcinoma by facilitating the Warburg effect.
MGP Promotes Colon Cancer Proliferation by Activating the NF-κB Pathway through Upregulation of the Calcium Signaling Pathway.
Small Nucleolar RNAs Determine Resistance to Doxorubicin in Human Osteosarcoma.
SNHG11 promotes cell proliferation in colorectal cancer by forming a positive regulatory loop with c-Myc.
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.
ApoE mimetic peptide targeted nanoparticles carrying a BRD4 inhibitor for treating Medulloblastoma in mice.
miR-744-5p mediates lncRNA HOTTIP to regulate the proliferation and apoptosis of papillary thyroid carcinoma cells.
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter.
UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPKα2/mTORC1-MYC positive feedback loop.
Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK signaling.
60S acidic ribosomal protein P1 (RPLP1) is elevated in human endometriotic tissue and in a murine model of endometriosis and is essential for endometriotic epithelial cell survival in vitro.
Deletion of FHL2 in fibroblasts attenuates fibroblasts activation and kidney fibrosis via restraining TGF-β1-induced Wnt/β-catenin signaling.
Programmed cell death protein 1 promotes hepatitis B virus transmission through the regulation of ERK1/2-mediated trophoblasts differentiation.
High mobility group AT-hook 2 and c-MYC as potential prognostic factors in pancreatic ductal adenocarcinoma.
Loss of RDM1 enhances hepatocellular carcinoma progression via p53 and Ras/Raf/ERK pathways.
Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling.
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
Promotion of esophageal adenocarcinoma metastasis via Wnt/ß-catenin signal pathway by sorting nexins 3.
Heat-Shock protein A12A is a novel PCNA-binding protein and promotes hepatocellular carcinoma growth.
MicroRNA-1236-3p inhibits human osteosarcoma growth.
Rab18 binds to classical swine fever virus NS5A and mediates viral replication and assembly in swine umbilical vein endothelial cells.
YTHDF1 Facilitates the Progression of Hepatocellular Carcinoma by Promoting FZD5 mRNA Translation in an m6A-Dependent Manner.
miR-4721, Induced by EBV-miR-BART22, Targets GSK3β to Enhance the Tumorigenic Capacity of NPC through the WNT/β-catenin Pathway.
GEF-independent Ran activation shifts a fraction of the protein to the cytoplasm and promotes cell proliferation.
Cyclin Y binds and activates CDK4 to promote the G1/S phase transition in hepatocellular carcinoma cells via Rb signaling.
Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling.
miR-140-3p enhances cisplatin sensitivity and attenuates stem cell-like properties through repressing Wnt/β-catenin signaling in lung adenocarcinoma cells.
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
Ginsenoside Rh4 suppresses aerobic glycolysis and the expression of PD-L1 via targeting AKT in esophageal cancer.
Identification of Cardiac Glycosides as Novel Inhibitors of eIF4A1-Mediated Translation in Triple-Negative Breast Cancer Cells.
KAP1 silencing relieves OxLDL-induced vascular endothelial dysfunction by down-regulating LOX-1.
RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice.
Apolipoprotein E2 modulates cell cycle function to promote proliferation in pancreatic cancer cells via regulation of the c-Myc-p21(Waf1) signalling pathway.
Capsaicin suppressed activity of prostate cancer stem cells by inhibition of Wnt/β-catenin pathway.
ACSL4 promotes hepatocellular carcinoma progression via c-Myc stability mediated by ERK/FBW7/c-Myc axis.
Overexpression of MEF2D contributes to oncogenic malignancy and chemotherapeutic resistance in ovarian carcinoma.
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
FOXA1 is Prognostic of Triple Negative Breast Cancers by Transcriptionally Suppressing SOD2 and IL6.
SIRT6 promotes the Warburg effect of papillary thyroid cancer cell BCPAP through reactive oxygen species.
Berberine Inhibits Growth of Liver Cancer Cells by Suppressing Glutamine Uptake.
Overexpression of KRT17 promotes proliferation and invasion of non-small cell lung cancer and indicates poor prognosis.
FKN Facilitates HK-2 Cell EMT and Tubulointerstitial Lesions via the Wnt/β-Catenin Pathway in a Murine Model of Lupus Nephritis.
The Anti-proliferative Activity of GnRH Through Downregulation of the Akt/ERK Pathways in Pancreatic Cancer.
MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.
DEPDC1 drives hepatocellular carcinoma cell proliferation, invasion and angiogenesis by regulating the CCL20/CCR6 signaling pathway.
A positive feedback loop of SIRT1 and miR17HG promotes the repair of DNA double-stranded breaks.
HOXA11-AS regulates JAK-STAT pathway by miR-15a-3p/STAT3 axis to promote the growth and metastasis in liver cancer.
LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis.
Regulation of circadian rhythms by NEAT1 mediated TMAO-induced endothelial proliferation: A protective role of asparagus extract.
MCP-induced protein 1 attenuates sepsis-induced acute lung injury by modulating macrophage polarization via the JNK/c-Myc pathway.
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway.
HMQ‑T‑F2 suppresses migration of the human cervical cancer HeLa cells by reversing EMT via the PI3K/Akt signaling pathway.
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
A novel oncogene TRIM63 promotes cell proliferation and migration via activating Wnt/β-catenin signaling pathway in breast cancer.
SIRT4 enhances the sensitivity of ER-positive breast cancer to tamoxifen by inhibiting the IL-6/STAT3 signal pathway.
lncRNA MALAT1 mediated high glucose-induced HK-2 cell epithelial-to-mesenchymal transition and injury.
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
Usp10 Modulates the Hippo Pathway by Deubiquitinating and Stabilizing the Transcriptional Coactivator Yorkie.
Targeting Frizzled-7 Decreases Stemness and Chemotherapeutic Resistance in Gastric Cancer Cells by Suppressing Myc Expression.
A novel tumor suppressor SPINK5 targets Wnt/β-catenin signaling pathway in esophageal cancer.
MYC status as a determinant of synergistic response to Olaparib and Palbociclib in ovarian cancer.
Dennd1a, a susceptibility gene for polycystic ovary syndrome, is essential for mouse embryogenesis.
A novel inhibitor of nuclear factor kappa-B kinase subunit gamma mutation identified in an incontinentia pigmenti patient with syndromic tooth agenesis.
USP36 protects proximal tubule cells from ischemic injury by stabilizing c-Myc and SOD2.
A Molecular Targeted Immunotherapeutic Strategy for Ulcerative Colitis via Dual-targeting Nanoparticles Delivering miR-146b to Intestinal Macrophages.
H(2)S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling.
STAT1-mediated inhibition of FOXM1 enhances gemcitabine sensitivity in pancreatic cancer.
MIR17HG-miR-18a/19a axis, regulated by interferon regulatory factor-1, promotes gastric cancer metastasis via Wnt/β-catenin signalling.
AKIP1 promotes early recurrence of hepatocellular carcinoma through activating the Wnt/β-catenin/CBP signaling pathway.
Myc and Dnmt1 impede the pluripotent to totipotent state transition in embryonic stem cells.
Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma.
Function of BRD4 in the pathogenesis of high glucose‑induced cardiac hypertrophy.
FOXC1 silencing inhibits the epithelial‑to‑mesenchymal transition of glioma cells: Involvement of β‑catenin signaling.
LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway.
Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis.
p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.
TRIP13 promotes the cell proliferation, migration and invasion of glioblastoma through the FBXW7/c-MYC axis.
LncRNA AC007271.3 promotes cell proliferation, invasion, migration and inhibits cell apoptosis of OSCC via the Wnt/β-catenin signaling pathway.
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice.
Carboxypeptidase E-ΔN promotes migration, invasiveness, and epithelial-mesenchymal transition of human osteosarcoma cells via the Wnt-β-catenin pathway.
miR-10b promoted melanoma progression through Wnt/β-catenin pathway by repressing ITCH expression.
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Baicalin induced colon cancer cells apoptosis through miR-217/DKK1-mediated inhibition of Wnt signaling pathway.
Enhanced expression of circular RNA hsa_circ_000984 promotes cells proliferation and metastasis in non-small cell lung cancer by modulating Wnt/β-catenin pathway.
ROS-Responsive Polymeric Micelles for Triggered Simultaneous Delivery of PLK1 Inhibitor/miR-34a and Effective Synergistic Therapy in Pancreatic Cancer.
Myricetin Suppresses the Propagation of Hepatocellular Carcinoma via Down-Regulating Expression of YAP.
P21-activated kinase 7 (PAK7) interacts with and activates Wnt/β-catenin signaling pathway in breast cancer.
The Orexin-A-Regulated Akt/mTOR Pathway Promotes Cell Proliferation Through Inhibiting Apoptosis in Pancreatic Cancer Cells.
Coagulation Factor X Regulated by CASC2c Recruited Macrophages and Induced M2 Polarization in Glioblastoma Multiforme.
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
R-spondin1/Wnt-enhanced Ascl2 autoregulation controls the self-renewal of colorectal cancer progenitor cells.
Plasma miR-199a-5p is increased in neutrophilic phenotype asthma patients and negatively correlated with pulmonary function.
POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling.
Knockdown of Sox2 Inhibits OS Cells Invasion and Migration via Modulating Wnt/β-Catenin Signaling Pathway.
Alpinetin inhibits proliferation and migration of ovarian cancer cells via suppression of STAT3 signaling.
Identification of a novel c-Myc inhibitor with antitumor effects on multiple myeloma cells.
High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma.
Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation.
Studying the mechanism of PLAGL2 overexpression and its carcinogenic characteristics based on 3'-untranslated region in colorectal cancer.
Inhibitory effects of aesculetin on the proliferation of colon cancer cells by the Wnt/β-catenin signaling pathway.
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Annexin A5 regulates hepatocarcinoma malignancy via CRKI/II-DOCK180-RAC1 integrin and MEK-ERK pathways.
c-MYC and reactive oxygen species play roles in tetrandrine-induced leukemia differentiation.
Actin-capping protein CapG is associated with prognosis, proliferation and metastasis in human glioma.
The ubiquitin ligase SCF(FBXW7α) promotes GATA3 degradation.
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
Atrazine exposure improves the proliferation of H22 cells in vitro and in vivo.
LGR5 promotes epithelial ovarian cancer proliferation, metastasis, and epithelial-mesenchymal transition through the Notch1 signaling pathway.
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
Nucleoside diphosphate kinase B promotes osteosarcoma proliferation through c-Myc.
Ube2v1-mediated ubiquitination and degradation of Sirt1 promotes metastasis of colorectal cancer by epigenetically suppressing autophagy.
Amphiphilic nanocarrier-induced modulation of PLK1 and miR-34a leads to improved therapeutic response in pancreatic cancer.
High expression of TMEM40 is associated with the malignant behavior and tumorigenesis in bladder cancer.
Ubiquitin-Specific Protease USP6 Regulates the Stability of the c-Jun Protein.
Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation.
MiR-17-5p enhances pancreatic cancer proliferation by altering cell cycle profiles via disruption of RBL2/E2F4-repressing complexes.
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
NIT1 suppresses tumour proliferation by activating the TGFβ1-Smad2/3 signalling pathway in colorectal cancer.
Nalmefene attenuates malignant potential in colorectal cancer cell via inhibition of opioid receptor.
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Cucurbitacin B Inhibits the Hippo-YAP Signaling Pathway and Exerts Anticancer Activity in Colorectal Cancer Cells.
Protein A from orange-spotted grouper nervous necrosis virus triggers type I interferon production in fish cell.
Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3β/β-catenin signaling pathway in breast cancer.
Resveratrol inhibits the growth of gastric cancer via the Wnt/β-catenin pathway.
A novel Anti-Cancer Stem Cells compound optimized from the natural symplostatin 4 scaffold inhibits Wnt/β-catenin signaling pathway.
Anticancer activity and potential mechanisms of 1C, a ginseng saponin derivative, on prostate cancer cells.
Overexpression of MYC binding protein promotes invasion and migration in gastric cancer.
Synergistic effect of receptor-interacting protein 140 and simvastatin on the inhibition of proliferation and survival of hepatocellular carcinoma cells.
Myosin 1b promotes cell proliferation, migration, and invasion in cervical cancer.
Wnt signaling induces radioresistance through upregulating HMGB1 in esophageal squamous cell carcinoma.
Nuclear galectin-1-FOXP3 interaction dampens the tumor-suppressive properties of FOXP3 in breast cancer.
RIZ1 negatively regulates ubiquitin-conjugating enzyme E2C/UbcH10 via targeting c-Myc in meningioma.
Whole exome-wide association study identifies a missense variant in SLC2A4RG associated with glioblastoma risk.
β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.
Overexpression of CIP2A is associated with poor prognosis in multiple myeloma.
Overexpression of SET oncoprotein is associated with tumor progression and poor prognosis in human gastric cancer.
Lin28B facilitates the progression and metastasis of pancreatic ductal adenocarcinoma.
Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication.
Synthesis and biological evaluation of 4-biphenylamino-5-halo-2(5H)-furanones as potential anticancer agents.
Epigenetic mediated zinc finger protein 671 downregulation promotes cell proliferation and tumorigenicity in nasopharyngeal carcinoma by inhibiting cell cycle arrest.
Axin1 up-regulated 1 accelerates stress-induced cardiomyocytes apoptosis through activating Wnt/β-catenin signaling.
Invasive Fusobacterium nucleatum activates beta-catenin signaling in colorectal cancer via a TLR4/P-PAK1 cascade.
Parkin regulates translesion DNA synthesis in response to UV radiation.
Correlations between TBL1XR1 and recurrence of colorectal cancer.
ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer.
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
Apobec-1 complementation factor regulates cell migration and apoptosis through Dickkopf1 by acting on its 3' untranslated region in MCF7 cells.
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Methylation of DACT2 promotes breast cancer development by activating Wnt signaling.
Hypoxia-inducible factor-2α promotes hepatocyte apoptosis during cholestasis.
Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation.
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Protective effect of autophagy in neural ischemia and hypoxia: Negative regulation of the Wnt/β-catenin pathway.
Knockdown of Rhotekin 2 expression suppresses proliferation and induces apoptosis in colon cancer cells.
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Autophagy plays an important role in stemness mediation and the novel dual function of EIG121 in both autophagy and stemness regulation of endometrial carcinoma JEC cells.
miR-367 promotes tumor growth by inhibiting FBXW7 in NSCLC.
Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites.
CO-releasing molecules-2 attenuates ox-LDL-induced injury in HUVECs by ameliorating mitochondrial function and inhibiting Wnt/β-catenin pathway.
Involvement of JNK signaling in IL4-induced M2 macrophage polarization.
GOLPH3 induces epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in epithelial ovarian cancer.
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway.
Long non-coding RNA MINCR promotes gallbladder cancer progression through stimulating EZH2 expression.
MicroRNA-146b, a Sensitive Indicator of Mesenchymal Stem Cell Repair of Acute Renal Injury.
CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis.
Atrazine promotes RM1 prostate cancer cell proliferation by activating STAT3 signaling.
High expression of hexokinase domain containing 1 is associated with poor prognosis and aggressive phenotype in hepatocarcinoma.
Aldehyde dehydrogenase 1A1 up-regulates stem cell markers in benzo[a]pyrene-induced malignant transformation of BEAS-2B cells.
High Expression of XRCC6 Promotes Human Osteosarcoma Cell Proliferation through the β-Catenin/Wnt Signaling Pathway and Is Associated with Poor Prognosis.
YPEL3 suppresses epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway.
Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma.
Magnetic gold nanoparticle-mediated small interference RNA silencing Bag-1 gene for colon cancer therapy.
Silencing Bag-1 gene via magnetic gold nanoparticle-delivered siRNA plasmid for colorectal cancer therapy in vivo and in vitro.
Cryptosporidium parvum rhomboid1 has an activity in microneme protein CpGP900 cleavage.
Zeb1 Is a Potential Regulator of Six2 in the Proliferation, Apoptosis and Migration of Metanephric Mesenchyme Cells.
PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway.
Loss-of-function Mutation in PMVK Causes Autosomal Dominant Disseminated Superficial Porokeratosis.
Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling.
Long Non-Coding RNA CCAT1 Acts as a Competing Endogenous RNA to Regulate Cell Growth and Differentiation in Acute Myeloid Leukemia.
Overexpression of Long Non-Coding RNA ZXF2 Promotes Lung Adenocarcinoma Progression Through c-Myc Pathway.
FOXQ1 mediates the crosstalk between TGF-β and Wnt signaling pathways in the progression of colorectal cancer.
MiR-125a suppresses tumor growth, invasion and metastasis in cervical cancer by targeting STAT3.
Low SFRP1 Expression Correlates with Poor Prognosis and Promotes Cell Invasion by Activating the Wnt/β-Catenin Signaling Pathway in NPC.
Senescent stromal cells induce cancer cell migration via inhibition of RhoA/ROCK/myosin-based cell contractility.
Novel taspine derivative 12k inhibits cell growth and induces apoptosis in lung cell carcinoma.
Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells.
Mammalian cell display for rapid screening scFv antibody therapy.
MRTF-A and STAT3 synergistically promote breast cancer cell migration.
Hepatitis B viral RNA directly mediates down-regulation of the tumor suppressor microRNA miR-15a/miR-16-1 in hepatocytes.
Expression and role of grainyhead-like 2 in gastric cancer.
Gong K, Song K, Wang H, Li L, Sun X, Sun L, Hao W, Chen ZS, Huang Y
International journal of biological sciences 2026;22(5):2215-2232
International journal of biological sciences 2026;22(5):2215-2232
GSK3β as a potential regulator in AML: A pan-cancer multi-omics analysis.
Qiu R, Zhou Y, Song S, Wang Z
PloS one 2026;21(3):e0344994
PloS one 2026;21(3):e0344994
SHP2 improved Late-onset fetal growth restriction via modulating ROS/BRD4/PI3K/YAP/PIGF signaling induced angiogenesis.
Li F, Li Y, Hao W, Zhang X, Shen X, Yang B, Zhang W, Fu L, Gu S
PloS one 2026;21(2):e0342649
PloS one 2026;21(2):e0342649
Exosome encapsulated albumin nanoparticles target delivery of DBET6 as a treatment for triple-negative breast cancer.
Yu H, Zhao J, Wu D, Yuan H
PloS one 2026;21(1):e0335890
PloS one 2026;21(1):e0335890
KIF23 Overexpression Promotes Cell Viability, Migration, and Invasion via the Wnt/β-Catenin Signaling Pathway in Anaplastic Thyroid Carcinoma.
Wu Y, Zheng C, Chen W, Xu T
International journal of endocrinology 2026;2026:7664607
International journal of endocrinology 2026;2026:7664607
Potential Anti-Cancer Drug 6RK73 Suppresses Ovarian Cancer Growth by Inactivating the AKT1/Sp1 Induced c-Myc Signaling Pathway.
Kuang S, Feng W, He S, Meng W, Yang C, Ning Y
Journal of Cancer 2026;17(2):245-256
Journal of Cancer 2026;17(2):245-256
Single-cell transcriptome analysis indicated that immune-related programmed cell death modification features could predict the clinical outcomes of patients with ovarian cancer.
Sun J, Jing L, Zhu X, Yang H, Sun Y, Lu X, Liu Z
Translational oncology 2026 May;67:102752
Translational oncology 2026 May;67:102752
Curcumin augments mitophagy via Nrf2-PINK1-mediated, Parkin-dependent ubiquitination to suppress ferroptosis in post-cardiac arrest brain injury.
Li Z, Xu W, Ren S, Zheng Q, Xing J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158035
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158035
Discovery of potent TNIK inhibitors containing a 1H-pyrrolo[2,3-b]pyridine scaffold as promising therapeutics for colorectal cancer.
Niu X, Zhang S, Xu B, Deng W, Zhang X, He H, Shi X, Tong M, Chen J, Qin M
European journal of medicinal chemistry 2026 May 5;309:118717
European journal of medicinal chemistry 2026 May 5;309:118717
The HSP90-dependent bioorthogonal PROTAC prodrug system enables tumor-selective and enhanced protein degradation.
Yin F, Song T, Song Y, Wang K, Zhang H, Jiang M, Wang Z, Fan X, Zhang Y, Wang S, Teng Y, Lun H, Wang S, Xie A, Wang Z, Zhang Z
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114828
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114828
Inhibiting mPGES-2 impedes renal cyst growth in mice with polycystic kidney disease.
Zhong DD, Hu C, Zhao LL, Shen Y, Zhang RM, Liu Y, Liu BH, Su W, Yang BX, Xiong H, Guo D, Sun D, Zou YY, Sun Y
Acta pharmacologica Sinica 2026 Mar;47(3):689-700
Acta pharmacologica Sinica 2026 Mar;47(3):689-700
Gallium-Doped MXene Nanozymes Protect Liver Through Multi-Death Pathway Blockade and Hepatocyte Regeneration.
Cai X, Deng J, Wang L, Su J, Xian D, Yan Y, Yang X, Wu C, Peng T, Ding Y, Quan G, Wang W, Zhou M, Lu C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e09079
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e09079
Network medicine modeling of the m⁶A regulatory landscape identifies a KLF6-WTAP axis as a therapeutic target in pulmonary fibrosis.
Xu C, Zhou Z, Lin Y, Zhang S, Cai S, Li B, Wang Z
Journal of translational medicine 2026 Mar 5;24(1)
Journal of translational medicine 2026 Mar 5;24(1)
tRF-3005a regulates exon skipping of SPAG4 by interacting with RALY to drive gastric cancer progression.
Cui H, Yuan Y, Yin Y, Gao R, Liu Z, Peng L, Wang J, Wang Z, Song T, Liu J
Cell death discovery 2026 Mar 24;12(1)
Cell death discovery 2026 Mar 24;12(1)
USP5-mediated CD73 deubiquitination drives osimertinib resistance via PI3K/AKT and glycolysis activation in LUAD.
Chen R, Han XH, Zhang Z, Han XJ, Xie J
iScience 2026 Mar 20;29(3):114916
iScience 2026 Mar 20;29(3):114916
Transcriptional readthrough precedes alternative splicing programs triggered in CML cells by imatinib.
Podszywałow-Bartnicka P, Shine M, Lin J, Neugebauer KM
Science advances 2026 Mar 20;12(12):eaea2475
Science advances 2026 Mar 20;12(12):eaea2475
KCTD1 stabilizes c-Myc to upregulate PD-L1 and suppress anti-tumor immunity in hepatocellular carcinoma.
Zhong D, Long S, Dai Y, Yin Y, Zhang Z, Ouyang M, Zhu X, Hou A, Qin Y, Wang Q, Gong M, Ding X
Cell death discovery 2026 Mar 2;12(1)
Cell death discovery 2026 Mar 2;12(1)
OsCPN10a, cooperating with OsCPN20 and OsHSP60-3B negatively regulate ABA signaling and enhance seed storability in rice.
Liao S, Wei Y, Zhu Y, Li K, Chen T, Zhao S, Wu F, Wang J, Yu P, Xie H, Chen L, Cai Q, Xie H, Zhang J
Journal of integrative plant biology 2026 Mar 16;
Journal of integrative plant biology 2026 Mar 16;
Heart-Specific and Conditional Deletion of the Immt Gene Reveals Its Role in Regulating Mitochondrial Structure and Total Heart Metabolism.
Kuwabara Y, Keezer C, Lin SJ, Rajput A, Molkentin JD
Cells 2026 Mar 12;15(6)
Cells 2026 Mar 12;15(6)
The role of FPR3 in remodeling the immune microenvironment and lung metastasis of colon adenocarcinoma.
Xu N, Xia T, Wu M, Ye F, Zhao W, Zhao M, Mao Y, Ge Y, Du J
Cellular signalling 2026 Jun;142:112420
Cellular signalling 2026 Jun;142:112420
Pyrimethamine regulates m6A modification of CCND1 via METTL14/YTHDF2 to inhibit hepatocellular carcinoma.
Han X, Wang K, Liu C, Yin S, Shao Y, Zhang J, Wang D, Pan G, Yu H
Bioorganic chemistry 2026 Jul 15;176:109892
Bioorganic chemistry 2026 Jul 15;176:109892
Aurintricarboxylic acid, an inhibitor of cystathionine γ-lyase, enhances the sensitivity of chemotherapy drugs in TNBC.
Han X, Fu H, Zhang Z, Wang J, Feng S, Jiang L, Chen L, Li H, Wang T
Translational oncology 2026 Jan;63:102602
Translational oncology 2026 Jan;63:102602
TAF1 acetyltransferase promotes colorectal carcinoma metastasis by catalyzing β-hydroxybutyrylation of KCTD9.
Su J, Zhao M, Feng W, Lin Y, Lu X, Xia Z, Cheng T, Liu Q, Cheng L, Pu C, Zhang A, Tang J, Yu B
Oncogene 2026 Jan;45(1):87-103
Oncogene 2026 Jan;45(1):87-103
Targeting aldose reductase in pulmonary fibrosis: Blocking de novo fatty acid synthesis halts pro-fibrotic M2 polarization.
Li J, Zhang Q, Zhao P, Mei X, Shi Y, Shao W, Yu X
International journal of biological macromolecules 2026 Jan;337(Pt 2):149590
International journal of biological macromolecules 2026 Jan;337(Pt 2):149590
Triglyceride lipase PNPLA2-independent suppression of c-MYC signaling by the metabolic coactivator ABHD5 in prostate cancer.
Lotvola A, Chen G, Zhou G, Granneman JG, Wang J
The Journal of biological chemistry 2026 Jan;302(1):111001
The Journal of biological chemistry 2026 Jan;302(1):111001
SPON2 acts as a tumor promoter in HR-positive/HER2-negative breast cancer by regulating β-catenin signaling.
Liu GY, Huang DP, Ge C, Li XY, Chen F, Fan JS, Tu HP
Clinical breast cancer 2026 Jan;26(1):298-305
Clinical breast cancer 2026 Jan;26(1):298-305
Pan-cancer multi-omics reveals DCAF7 as an immune-modulating prognostic driver and Wnt/β-catenin activator in hepatocellular carcinoma.
Luan R, Lin H, Zhao X, Li J, Chen M, Luo S, Lin X
Clinical and translational medicine 2026 Jan;16(1):e70572
Clinical and translational medicine 2026 Jan;16(1):e70572
PPIA regulates fatty acid and glutamine metabolism in lung adenocarcinoma based on multiomics prognostic model and experiment validation.
Gan Y, Wei W, Jiang B, Zhang X, Jiang L, Teng L, Xie X, Liu Y, Xie Q, Jiang L
Scientific reports 2026 Jan 5;16(1):4154
Scientific reports 2026 Jan 5;16(1):4154
Suppressing the Aberrant Transcriptional Functionality of EWS::FLI1 Oncoprotein by Designer polyQ Fusions with Its Homologous Peptides.
Duan HT, Zhang XL, Jiang LL, Hu HY
Biomedicines 2026 Jan 30;14(2)
Biomedicines 2026 Jan 30;14(2)
Inhibition of the RORC/GPX4 mediated ferroptosis regulatory axis suppresses tumor growth and alleviates enzalutamide resistance in prostate cancer.
Li Y, Zhang B, Zhang Z, Yan W, Wang H, Xu X, Lv A, Liao Z, Guo L
Cellular & molecular biology letters 2026 Jan 24;31(1):11
Cellular & molecular biology letters 2026 Jan 24;31(1):11
Neutrophil-derived exosomes inhibit gastric cancer progression via miR-101-3p-mediated suppression of MCL1.
Wang J, Zhang J, Qian Y, Wang Y, Wang S, Fan B, Shi J, Wang J, Meng S, Dong X, Fu M, Zhang X, Ji R, Fang X, Zhang X
Cancer cell international 2026 Jan 21;26(1):88
Cancer cell international 2026 Jan 21;26(1):88
Upregulated ARMCX1 suppresses nasopharyngeal carcinoma progression by promoting TRIM21-mediated β-catenin degradation.
Hu Z, Zhuo E, Guo J, Wu Y, Sun X, Qiu H, Zhou Y, Tan X, Zhang X
Cellular oncology (Dordrecht, Netherlands) 2026 Jan 14;49(1):25
Cellular oncology (Dordrecht, Netherlands) 2026 Jan 14;49(1):25
SOX2 is a dispensable modulator of NUT carcinoma oncogenesis in mice.
Luo C, Zheng D, Elnegiry A, Bhatara S, Mias GI, Tsoi MF, Yu J, Gu B
Life science alliance 2026 Feb;9(2)
Life science alliance 2026 Feb;9(2)
The Deubiquitinating Enzyme USP46 Abolishes Cell Survival of Prostate Cancer via Enhancing BECN1-Dependent Autophagy.
Yang Y, Cao H, Sun P, Feng Y, Chen L, Gao R
Biotechnology and applied biochemistry 2026 Feb;73(1):231-238
Biotechnology and applied biochemistry 2026 Feb;73(1):231-238
Role of the transmembrane domain in severe acute respiratory syndrome (SARS) coronavirus 2 spike for palmitoylation and membrane fusion.
Abdulrahman DA, Veit M
Protein science : a publication of the Protein Society 2026 Feb;35(2):e70482
Protein science : a publication of the Protein Society 2026 Feb;35(2):e70482
NRAV promotes HCC stemness via the m6A-regulated let-7c-5p/LIN28B axis.
Chen Y, Dai S, Zhuang L, Cai W, Chen H, Zhao J, Zhang F, Chen L, Cheng CS
Cancer gene therapy 2026 Feb;33(2):171-185
Cancer gene therapy 2026 Feb;33(2):171-185
Exploring the potential mechanisms of PFAS exposure on colorectal cancer via combined bioinformatics analyses and experiments.
Hao W, Chen X, Xin H, Wang Z, Wen T, Xu D, Ma H
Ecotoxicology and environmental safety 2026 Feb;311:119870
Ecotoxicology and environmental safety 2026 Feb;311:119870
A novel PVA/QCS/AgNP hydrogel with antibacterial and healing-promoting efficacy for preventing postoperative pancreatic fistula in rats.
Zhou Y, Chen F, Lin R, Huang H, Pan M
Colloids and surfaces. B, Biointerfaces 2026 Feb;258:115251
Colloids and surfaces. B, Biointerfaces 2026 Feb;258:115251
Tissue-Resident Macrophage-Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p-TBK1.
An X, Li J, Wang L, Li C, Jin Z, Yao Y, Jiang M, Lin W, Wang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(7):e04930
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(7):e04930
PRKD1/EIF5A/β-catenin axis inhibits tumorigenesis and metastasis in non-small-cell lung cancer.
Wang Y, Zhang M, Fang L, Qu J, Huo C, Li R, Yao J, Qu Y
Clinical and experimental medicine 2026 Feb 8;26(1):134
Clinical and experimental medicine 2026 Feb 8;26(1):134
Antioxidant and Anti-Aging Effects of Porphyra-334 Produced from Saccharomyces cerevisiae in Human Skin Models.
Park S, Park S, Park NH, Lee ES, Myoung K, Baek HS, Jang J, Nam SJ, Ko J, Lee CS
Marine drugs 2026 Feb 28;24(3)
Marine drugs 2026 Feb 28;24(3)
A DNA Methylation-Dependent NOP56/MYC Positive Feedback Loop Promotes the Proliferation and Migration of Non-Small Cell Lung Cancer Through Regulating Ribosome Biogenesis.
Zhu C, Zhang X, Zhang Y, Wei X, Shang Y
Cancers 2026 Feb 26;18(5)
Cancers 2026 Feb 26;18(5)
DNMT3b promotes proliferation and invasion by mediating HOPX DNA methylation in lung cancer.
Guan K, Zhao S, Zhang G, Wang Y, Song D, Ding Y
iScience 2026 Feb 20;29(2):114347
iScience 2026 Feb 20;29(2):114347
MUL1 suppresses cervical cancer progression by targeting FUNDC1 for ubiquitination and inhibiting DRP1-dependent mitophagy.
Li Y, Wang F, Fang Z, Sun H
Journal of molecular histology 2026 Feb 16;57(2):79
Journal of molecular histology 2026 Feb 16;57(2):79
Asporin regulates glycolysis and stemness of gastric cancer cells.
Xu G, Cai Z, Zhuang Y, Wang H, Lin Q, Guo T, Tao H
Journal of molecular histology 2026 Feb 13;57(2):74
Journal of molecular histology 2026 Feb 13;57(2):74
KIF20A inhibits TRIM21-dependent ubiquitination of DHX9 to boost SOX2 stability, enhancing OSCC stemness and ferroptosis resistance.
Zhang Z, Li Y, Hu J, Tang X, Li Z, Sun X, Feng D, Yao Y, Mao C, Tao Y, Xie L, Luo H, Li Y, Yu X, Peng X, Cong L, Jiang Y
Cell death & disease 2026 Feb 11;17(1):218
Cell death & disease 2026 Feb 11;17(1):218
Structural characterization and anti-hepatic fibrosis effects of a novel polysaccharide from Astragalus complanatus seeds.
Zhu ZF, Wang SY, Liu XF, Liu N, Dong DC, Qi YC, Li N, Wang N, Tan J, Jia C, Cai RQ, Li XQ, Cao W
Carbohydrate polymers 2026 Feb 1;373:124661
Carbohydrate polymers 2026 Feb 1;373:124661
cGAS-STING Pathway-Induced BST2 Enhances HPV-Infected Keratinocyte Proliferation in Condyloma Acuminata.
Huang H, Liu L, Xie X, Cao Y, Gu Z
Biomedicines 2026 Feb 1;14(2)
Biomedicines 2026 Feb 1;14(2)
Angiopep-2-decorated bacterial outer membrane vesicles penetrate the blood-brain barrier for glioblastoma chemo-immunotherapy.
Shah PT, Lou Z, Zhu X, Jin W, Chen C, Hu T, Guo P, Zhao X, Li F, Xiaoliang Y, Wu Z, Wu C
Drug delivery 2026 Dec 31;33(1):2660007
Drug delivery 2026 Dec 31;33(1):2660007
Genetic and pharmaceutical manipulation of H3K9 methyltransferase Suv39h1 promotes liver regeneration by unleashing HMGB2 transcription.
Lu Y, Zhou J, Miao X, Zeng S, Qin L, Xu Y, Wang S, Li Z
Experimental & molecular medicine 2026 Apr;58(4):1158-1171
Experimental & molecular medicine 2026 Apr;58(4):1158-1171
miRNA‑378a‑5p attenuates the development of abdominal aortic aneurysm via ABLIM1‑MKL1 signaling pathways.
Wang J, Zou Y, Wang Y, Yang Z, Liu D, Su X, Song H, Xu K, Yan C, Liu D, Han Y
International journal of molecular medicine 2026 Apr;57(4)
International journal of molecular medicine 2026 Apr;57(4)
Marek's disease virus hijacks host nucleotide metabolism via UL23-mediated c-Myc activation.
Wang Q, Shao H, Qian K, Ye J, Qin A
Veterinary microbiology 2026 Apr;315:110958
Veterinary microbiology 2026 Apr;315:110958
The RNA methyltransferase NSUN2 catalyzes 5-methylcytosine (m(5)C) on IL1B mRNA to promote transcript stability.
Wang J, Yan L, Jia R, Guo J
The Journal of biological chemistry 2026 Apr;302(4):111290
The Journal of biological chemistry 2026 Apr;302(4):111290
Epigenetic H3K4me3 activation of miR-155-5p promotes intervertebral disc degeneration via autophagy and ageing in nucleus pulposus cells.
Wang X, Sun H, Xiao W, Zhang Y, Lu X, Gong Z, Li D, Liu S, Xia X, Wang H, Shao M, Xu G, Ma X
Non-coding RNA research 2026 Apr;17:112-127
Non-coding RNA research 2026 Apr;17:112-127
Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression.
Guo S, Chen X, Wang H, Zhou J, Lu P, Liu J, Chai K, Zhang J, Yang S, Lu S, Gao Y, Jin Z, Tao X, Hu Z, Li Q, Wu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e07008
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e07008
Hsp70-Targeting Chimeras Enable Dual Proteasomal and Lysosomal Degradation of Intracellular and Extracellular Proteins.
Wang Z, Li P, Yin F, Zhang H, Wang S, Teng Y, Fan X, Wang K, Zhang Y, Lun H, Song T, Wang Z, Zhang Z
Journal of medicinal chemistry 2026 Apr 9;69(7):8417-8432
Journal of medicinal chemistry 2026 Apr 9;69(7):8417-8432
MYC Addiction as a Targetable Vulnerability in Nelarabine-Resistant T-Cell Acute Lymphoblastic Leukemia.
Gao J, Lin C, Chen S, Mo Q, Bao C, Deng H, Chen Z, Hao W, Zhang L, Wei M
Cancer science 2026 Apr 8;
Cancer science 2026 Apr 8;
AnnoNet-TCMs: An annotation network-driven discovery of novel active compounds and mechanisms in traditional Chinese medicine.
Yan X, Guo Z, Zhou F, Cui Y, Zhang Z, Jing Z, Wang L, Fan Z, Lu J, Xing X, Yang H
Journal of advanced research 2026 Apr 5;
Journal of advanced research 2026 Apr 5;
Metformin hydrochloride regulates glycolysis and inhibits PEDV replication by inhibition of PI3K-AKT signaling pathway.
Zhang X, Li Y, Yuan J, Li Q, Hu X, Song Z, Sun Z, Song Y, Zhong Y, Liao G, Ding J, Yang S, Song Z
Journal of virology 2026 Apr 21;100(4):e0014726
Journal of virology 2026 Apr 21;100(4):e0014726
CGF induces ROS-mediated metabolic reprogramming and mitochondrial dysfunction to suppress colorectal cancer progression.
Jiang J, Zhang X, Sun Y, Chen J, Yuan B, Li X, Chen X, Chen X, Li R
iScience 2026 Apr 17;29(4):115273
iScience 2026 Apr 17;29(4):115273
KIAA1429 promotes clear cell renal cell carcinoma progression by regulating MYC mRNA stability.
Zhu X, Shen C, Zhang Y, Chen X, Zhang W, Zheng B, Chen Z
iScience 2026 Apr 17;29(4):115198
iScience 2026 Apr 17;29(4):115198
KRT15 identified by scRNA-Seq and machine learning as stemness regulator and prognostic biomarker in ESCC.
Xiong K, Zhu Y, Fang H, Sun X, Li Z, Tuerxun D, Zhang P
iScience 2026 Apr 17;29(4):115020
iScience 2026 Apr 17;29(4):115020
Neddylation of STAT3 is a potential therapeutic target for MASLD.
Liu F, Zhao F, Du M, Ma J, Shang Y, Liu Z, Zhu Y, Zhang Z, Xie P
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 15;1872(6):168261
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 15;1872(6):168261
African swine fever virus pE199L, as a mitophagy receptor, suppresses antiviral innate immunity to promote viral replication.
Li X, Ren B, Zhang D, Dan M, Liu D, Zhang Z, Zhao J, Nan Y, Hiscox JA, Stewart JP, Zhu Z, Zhao Q, Sun Y
Autophagy 2026 Apr 11;:1-20
Autophagy 2026 Apr 11;:1-20
Copper Transporter 1‑Mediated Deregulation of Copper Homeostasis Impacts MYC and Oxidative Phosphorylation Pathways and Increases the Sensitivity of Tumor Cells to Complex I Inhibitors.
Mouawad R, Eisa NH, Balia A, Roy J, Neamati N
ACS pharmacology & translational science 2026 Apr 10;9(4):902-924
ACS pharmacology & translational science 2026 Apr 10;9(4):902-924
CDK4/6 and BET inhibitors synergistically suppress pancreatic tumor growth and epithelial-to-mesenchymal transition by regulating the GSK3β-mediated Wnt/β-catenin pathway.
Gu J, Dai Z, Shen T, Chen X, Yang Z, Sun S, Chen D, Luo H, Wang X, Xu J
Cancer drug resistance (Alhambra, Calif.) 2025;8:52
Cancer drug resistance (Alhambra, Calif.) 2025;8:52
CYMP-AS1 Promotes Ovarian Cancer Progression by Enhancing the Intracellular Translocation of hnRNPM and Reducing the Stability of AXIN2 mRNA.
Wang Y, Meng Y, Xia W, Liang Y, Wang Y, Li P, Fang L
Oncology research 2025;33(8):2141-2159
Oncology research 2025;33(8):2141-2159
circACTN4 promotes breast cancer cell cycle progression and oncogenesis via c-MYC induced histone H4 acetylation.
Liu K, Wang X, Yang X, Shi B, Xing L, Chen J
Oncology research 2025;33(7):1709-1722
Oncology research 2025;33(7):1709-1722
Splicing factor PTBP1 promotes hepatocarcinogenesis via oncogenic splice-switching of MAPT.
Zheng W, Shang Y, DU K, Luo A, Pei L, Li M, Zhang G, Deng M
Oncology research 2025;33(5):1121-1133
Oncology research 2025;33(5):1121-1133
ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway.
Peng J, Xue Y, Cai Z, Li Z, Han K, Lin X, Li Y, Zhuo Y
Oncology research 2025;33(10):3127-3154
Oncology research 2025;33(10):3127-3154
TMEM105 modulates disulfidptosis and tumor growth in pancreatic cancer via the β-catenin-c-MYC-GLUT1 axis.
Yin Y, Sun Y, Yao H, Yu F, Jia Q, Hu C, Zhu Y, Duan Z, Liu D, Sun Y, Huo Y, Yang M, Liu W
International journal of biological sciences 2025;21(5):1932-1948
International journal of biological sciences 2025;21(5):1932-1948
Platycodin D Enhances Glioma Sensitivity to Temozolomide by Inhibition of the Wnt/β-Catenin Pathway.
Li H, Ouyang J, Wang X, Qian C
Drug design, development and therapy 2025;19:1811-1824
Drug design, development and therapy 2025;19:1811-1824
MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma.
Qi R, Fang C, Liu P, Gu W, Shi C, Zhang G, Qiu F
Frontiers in genetics 2025;16:1615018
Frontiers in genetics 2025;16:1615018
T cell-mediated immune surveillance conferred by latent Epstein-Barr virus genes suppresses a broad spectrum of tumor formation through NKG2D-NKG2DL interactions.
Jin Y, Guo Y, Kawano Y, Sasatani M, Ohki S, Yamane K, Ota Y, Tamura Y, Sotomaru Y, Baba Y, Yasuda T
Frontiers in immunology 2025;16:1597731
Frontiers in immunology 2025;16:1597731
LINC01559 drives osimertinib resistance in NSCLC through a ceRNA network regulating miR-320a/IGF2BP3 axis.
Xu L, Zhang Y, Xing L, Zhou Y, Chang N, Xi H, Xu X, Zhang J
Frontiers in pharmacology 2025;16:1592846
Frontiers in pharmacology 2025;16:1592846
Gut microbiota-derived metabolite phenylacetylglutamine inhibits the progression of prostate cancer by suppressing the Wnt/β-catenin signaling pathway.
Lv J, Jin S, Zhou Y, Fu C, Shen Y, Liu B, Li J, Li M, Zhang Y, Feng N
Frontiers in pharmacology 2025;16:1528058
Frontiers in pharmacology 2025;16:1528058
Human fibrosarcoma cells selected for ultra-high doxorubicin resistance, acquire trabectedin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression.
Morinaga S, Han Q, Mizuta K, Kang BM, Bouvet M, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Higuchi T, Tsuchiya H, Demura S, Hoffman RM
Frontiers in oncology 2025;15:1704021
Frontiers in oncology 2025;15:1704021
Developing a prognostic stratification model based on glutathione metabolism in thyroid cancer and validating RRM2's tumor-promoting role.
Ao W, Liu TH, Yin DT, Zhao WX
Frontiers in oncology 2025;15:1700439
Frontiers in oncology 2025;15:1700439
CMSP suppresses oral squamous cell carcinoma progression by targeting the JAK2/STAT3/c-Myc axis.
Lu Y, Yao M, Wang D, Higuchi D, Lu H, Shang H, Dong B, Zhang J, Jin R, Liu T
Frontiers in oncology 2025;15:1671797
Frontiers in oncology 2025;15:1671797
Targeting the N-cadherin/β-catenin axis with MSAB reverses malignant phenotypes in blast crisis of CML.
Zhou Y, Jian S, Lu L, Li X, Qiu R
Frontiers in oncology 2025;15:1657508
Frontiers in oncology 2025;15:1657508
O-GlcNAcylation of YTHDF2 antagonizes ERK-dependent phosphorylation and inhibits lung carcinoma.
Li J, Zhou W, Zhang J, Ma L, Lv Z, Geng Y, Chen X, Li J
Fundamental research 2025 Sep;5(5):2388-2396
Fundamental research 2025 Sep;5(5):2388-2396
METTL3 Mediates Wnt/β-Catenin Pathway in Epithelial-Mesenchymal Transition of 16HBE Cells Induced by Beryllium Sulphate.
Yan C, Li G, Huang L, Zhang Z
Journal of applied toxicology : JAT 2025 Sep;45(9):1787-1797
Journal of applied toxicology : JAT 2025 Sep;45(9):1787-1797
ZMYND8 promotes the Warburg effect and tumorigenesis through c-Myc activation in pancreatic cancer.
Liu H, Zhao Z, Wu C, Chen J, He Z, Jiang K
Oncogene 2025 Sep;44(34):3083-3095
Oncogene 2025 Sep;44(34):3083-3095
A Small Molecular Weight Saccharide Fraction From Panax quinquefolium L. Inhibited Non-Small Cell Lung Cancer via Endoplasmic Reticulum-Stress Mediated Apoptosis.
Lü JL, Liang J, Zhang Y, Liu XQ, Wang WF, Kuang HX, Xia YG
Phytotherapy research : PTR 2025 Sep;39(9):3868-3885
Phytotherapy research : PTR 2025 Sep;39(9):3868-3885
The chromatin remodeling factor BAP18 promotes non-small cell lung cancer progression via the recruitment of β-catenin with the transcriptional coactivator complex ACTL6A-PAF1.
Hao J, Hu Q, Li X, Shi S, Na F, Zeng K, Li H, Zhao Y, Zhao M
The Journal of biological chemistry 2025 Sep;301(9):110596
The Journal of biological chemistry 2025 Sep;301(9):110596
LRK10L3 and BAK1 are collaboratively involved in extracellular ATP-regulated seedling growth of Arabidopsis thaliana.
Dong X, Xu J, Fu Y, Wang T, Yin H, Li Y, Yu L, Zhu R, Kang E, Shang Z
The New phytologist 2025 Sep;247(6):2709-2725
The New phytologist 2025 Sep;247(6):2709-2725
H3K36me3-Guided m(6)A Modification of Oncogenic L1CAM-AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma.
Wang T, Han L, Huo Y, Zhang L, Huang Y, Zhang N, Yang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e14909
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e14909
Low-intensity pulsed ultrasound stimulation to treat renal fibrosis through inhibiting tubular IL-1R.
Huang Z, Dong J, Fu Z, Li L, Liu S, Wu L, Guo H, Bian A, Liu K, Sun W, Xing C, Crowley SD, Ren J, Kong X, Mao H
JCI insight 2025 Sep 9;10(17)
JCI insight 2025 Sep 9;10(17)
Cytoplasmic TRIM24 promotes colorectal cancer cell proliferation by activating Wnt/β-catenin signaling.
Wang Y, Yao Y, Liu Z, Long S, Yi F, Fang Q, Wu D, Zhu Q, Zai H, Xiao S, Wan F, Fu K
Nature communications 2025 Sep 29;16(1):8598
Nature communications 2025 Sep 29;16(1):8598
YTHDF2 alleviates the radioresistance of rectal cancer cells by targeting methylated MYC.
Fang Y, Shang S, Chen G, Chen D, Yu J
Journal of radiation research 2025 Sep 23;66(5):459-472
Journal of radiation research 2025 Sep 23;66(5):459-472
Kuwanon A Targeted YWHAB in Hepatocellular Carcinoma Cells to Inhibit the Raf/MEK/ERK Signaling Pathway.
Xu J, Chang H, Wang Y, Du Y, Zhong L, Cui H
Cells 2025 Sep 23;14(19)
Cells 2025 Sep 23;14(19)
Slow-Release Prostacyclin Agonist-Immersed Sheet Implantation Suppresses Liver Fibrosis via Hippo Signaling Pathway Activation.
Fujii W, Tomimaru Y, Kobayashi S, Torigata K, Hasegawa K, Harada A, Sasaki K, Hasegawa S, Yamada D, Akita H, Noda T, Takahashi H, Imamura H, Kodama T, Terai S, Sawa Y, Miyagawa S, Doki Y, Eguchi H
Hepatology research : the official journal of the Japan Society of Hepatology 2025 Oct;55(10):1353-1366
Hepatology research : the official journal of the Japan Society of Hepatology 2025 Oct;55(10):1353-1366
S100A9 promotes resistance to anti-PD-1 immunotherapy in hepatocellular carcinoma by degrading PARP1 and activating the STAT3/PD-L1 pathway.
Zhou X, Qiao C, Chu X, Yang Y, Man H, Liu J, Li Y, Xu Z, Li H, Shan X, Lian Z, Lu Y, Wang W, Yu D, Sun X, Li B
Cellular oncology (Dordrecht, Netherlands) 2025 Oct;48(5):1433-1447
Cellular oncology (Dordrecht, Netherlands) 2025 Oct;48(5):1433-1447
Reprogramming Iron Metabolism via the RIG-I/c-Myc/FTH Axis Mitigates Renal Ischemia-Reperfusion Injury.
Zhang Y, Xing J, Yao L, Zou Y, Peng H, Yi X, Bai L, Yu Y, Liu H, Li X, Zhai X
Antioxidants & redox signaling 2025 Oct;43(10-12):622-636
Antioxidants & redox signaling 2025 Oct;43(10-12):622-636
USP45 Represses Melanoma Development by Deubiquitinating and Stabilizing Tumor Suppressor MRGPRF.
Zhang W, Chen L, Zhao J, Ma A, Shi W, Zhang Y, Tang Z, Guo J, Xu Z, Zhou J, Tang S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e03106
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e03106
HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancer.
Xiao Y, Xu Y, Wang H, Yang F, Ding XH, Fu T, Chen L, Jin X, Zhao YX, Wang Y, Chen F, Shao ZM, Jiang YZ
Cell metabolism 2025 Oct 7;37(10):2030-2047.e7
Cell metabolism 2025 Oct 7;37(10):2030-2047.e7
MDA-9/Syntenin promotes glioma cell proliferation and invasion via exosome-mediated activation of the PI3K-AKT signaling pathway.
Zheng Y, Yu X, Zhong Z, Li M
Biochemical and biophysical research communications 2025 Oct 30;786:152720
Biochemical and biophysical research communications 2025 Oct 30;786:152720
Canagliflozin inhibits hepatic stellate cells activation and proliferation by inhibiting PP2A-mediated β-catenin dephosphorylation to attenuate hepatic fibrosis.
Peng L, Zou Z, Zhou L, Li L, Lu W, Chen C, Xu Y, Liu Y, Lin J, Ye J
International immunopharmacology 2025 Oct 30;164:115347
International immunopharmacology 2025 Oct 30;164:115347
TRIM21 as a potential prognostic biomarker and therapeutic target affects the growth of pancreatic cancer.
Sun D, Zheng S, Wang S, Xue Y, Song S, Bai Y, Li X, Ci Y
Discover oncology 2025 Oct 30;16(1):1993
Discover oncology 2025 Oct 30;16(1):1993
RPL22L1-Myc positive feedback loop drives lung adenocarcinoma progression.
Wu Y, Zhu Y, Jiang R, Gu W, Lu L, Yao N, Du B, Lai J
Cancer cell international 2025 Oct 3;25(1):333
Cancer cell international 2025 Oct 3;25(1):333
Deacetylation of TALDO1 by HDAC6 promotes glycolysis and nasopharyngeal carcinoma progression through a moonlighting function.
Peng X, Zhou P, Zhang K, Chen L, Tang M, Zhou Q, Peng J, Yang L
Cell death & disease 2025 Oct 21;16(1):743
Cell death & disease 2025 Oct 21;16(1):743
Pan-cancer analysis of role of LOXL4 and experiment validation in osteosarcoma.
Chen W, Xie F, Lv J, Huang D, Zhong R, Wen Z, Sun J, Zheng S, Liu W, Zhong H, Huang S
Discover oncology 2025 Oct 21;16(1):1926
Discover oncology 2025 Oct 21;16(1):1926
ALKBH8-mediated codon-specific translation promotes colorectal tumorigenesis.
Qian Y, Wu C, Wei S, Yan S, Peng J, Yu L, Gao Y, Hou J, Yu W, Chen Z, Zhang J, Gao X
Nature communications 2025 Oct 13;16(1):9075
Nature communications 2025 Oct 13;16(1):9075
Cedrol impedes lung cancer metastasis by reducing tumor-associated macrophage polarization mediated by MYC-driven aerobic glycolysis.
Li Q, Liu Y, Zhang L, Zheng Y, Feng X, Wang Y
Human cell 2025 Oct 10;38(6):177
Human cell 2025 Oct 10;38(6):177
Obesity induced by a high-fat diet regulates the MYC‒PPIL1 network in the mediation of asthenozoospermia.
Shi M, Xu L, Zheng W, Lin X, Qin G
Basic and clinical andrology 2025 Oct 10;35(1):38
Basic and clinical andrology 2025 Oct 10;35(1):38
Centromere protein I facilitates breast cancer tumorigenesis and disease progression through modulation of Wnt/β-Catenin signaling.
Wu C, Zhou Y, Mu Y, Cheng Y, Xu W, Huang M, Xu J, Li M, Gu J, Meng X, Qian D
Cancer cell international 2025 Oct 10;25(1):348
Cancer cell international 2025 Oct 10;25(1):348
Long noncoding RNA ENST00000458139 promotes mitochondrial dysfunction and apoptosis of podocytes in diabetic kidney disease through binding with SNRPA1.
Yang M, Fan X, Lang Y, Hu J, Wang Q, Shen N, Zhang D, Chai S, Wang R, Lv Z
International immunopharmacology 2025 Oct 10;163:115232
International immunopharmacology 2025 Oct 10;163:115232
KIF23 silencing suppresses papillary thyroid carcinoma metastasis by regulating mitophagy via Wnt/β-catenin pathway.
Liu Y, Zhang J, Chen Y, Zhu M, Chen W, Hao Z, Deng Y, Han X, Xu J
Endocrine connections 2025 Oct 1;14(10)
Endocrine connections 2025 Oct 1;14(10)
TRIM39-mediated deubiquitination upregulates RNF168 to evade autophagy-ferroptosis in triple-negative breast cancer.
Yao X, Shen X, Fan Y, Wang H
NPJ breast cancer 2025 Oct 1;11(1):108
NPJ breast cancer 2025 Oct 1;11(1):108
Integrating network pharmacology and pharmacological evaluation for investigating the active ingredient of Chinese herbal formula Zhuhuang Granule in psoriasis.
Wang J, Luo M, Zhang Y, Pan Y, Huang P, Zhou R, Yan Y, Wang B, Jiang M, Ran C, Wang H
Pathology, research and practice 2025 Nov;275:156201
Pathology, research and practice 2025 Nov;275:156201
Glioma cells produce soluble PD-L1 via the Wnt/β-catenin signaling pathway to suppress CD8+ T cell activity.
Zhou Z, Wang Y, Wang Y, Yuan C, Lin J, Bai X, Chen Y, Hu M, Ding X
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):168013
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):168013
Fragile X mental retardation 1 gene FMR1 promotes proliferation, migration, and invasion of gastric cancer cells via c-MYC.
Han Y, Mao C, Zhou K, Liang M, Zhao L, Hong Y, Zhang J, Hu N, Wu F
Journal of translational medicine 2025 Nov 3;23(1):1210
Journal of translational medicine 2025 Nov 3;23(1):1210
USP30-AS1 Dictates Breast Cancer Cell Fate and Chemoresistance via a miR-3646/FZD7/Wnt/β-Catenin Circuit.
He Q, Yang S, Xin Q, Jiang Y, Jiang L, Xu N
Current issues in molecular biology 2025 Nov 24;47(12)
Current issues in molecular biology 2025 Nov 24;47(12)
CDC26 facilitates ferroptosis through SLC7A11 degradation and cell cycle arrest.
Lin J, Chen F, Tang H, Cai X, Huang M, Liang R, Kang R, Tang D, Liu J
Clinical and experimental medicine 2025 Nov 18;26(1):11
Clinical and experimental medicine 2025 Nov 18;26(1):11
Transcriptional readthrough precedes alternative splicing programs triggered in CML cells by imatinib.
Podszywałow-Bartnicka P, Shine M, Lin J, Neugebauer KM
bioRxiv : the preprint server for biology 2025 Nov 14;
bioRxiv : the preprint server for biology 2025 Nov 14;
Phytosphingosine suppresses gastric cancer through SFRP4/β-catenin axis-mediated Wnt signaling pathway inhibition.
Liu Y, Guo R, Xue C, Zhang X, Xiao F, Zhao X, Zhu Z, Li K
Chemico-biological interactions 2025 Nov 1;421:111749
Chemico-biological interactions 2025 Nov 1;421:111749
Phospho-TRIM21 orchestrates RPA2 ubiquitination switch to promote homologous recombination and tumor radio/chemo-resistance.
Zhang J, Chen B, Xu F, Wang R, Zhao X, Yao Z, Zhang J, Zhou S, Xu A, Wu L, Zhao G
Oncogene 2025 May;44(16):1106-1117
Oncogene 2025 May;44(16):1106-1117
The selenocysteine-containing protein SELENOT maintains dopamine signaling in the midbrain to protect mice from hyperactivity disorder.
Guo Q, Li ZF, Hu DY, Li PJ, Wu KN, Fan HH, Deng J, Wu HM, Zhang X, Zhu JH
The EMBO journal 2025 May;44(10):2906-2927
The EMBO journal 2025 May;44(10):2906-2927
Histone acetyltransferase BmMOF inhibits the proliferation of the Bombyx mori nucleopolyhedrovirus by targeting Bmp53.
Miao M, Bai SM, Huang YY, Zhang JW, Xu KL, Chen Y, Qian QT, Dong J, Nie HM, Mei J, Tong FD, Yu W
International journal of biological macromolecules 2025 May;305(Pt 2):141186
International journal of biological macromolecules 2025 May;305(Pt 2):141186
Foxp3 inhibits PCV2 replication by reducing the ATPase activity of Rep.
Jiang R, Huang Q, Shen R, Zhang Y, Zhou L, Ge X, Han J, Guo X, Yang H
Veterinary microbiology 2025 May;304:110441
Veterinary microbiology 2025 May;304:110441
HKDC1 promotes colorectal cancer progression by regulating RCOR1 expression to activate the Wnt/β-catenin pathway, enhancing proliferation, migration, and epithelial-mesenchymal transition.
Huang S, Pang Q, Zhang Y, Cao J
The Journal of biological chemistry 2025 May;301(5):108478
The Journal of biological chemistry 2025 May;301(5):108478
Role of noncanonical histone H2A variant, H2A.Z, to maintain proper centromeric transcription and chromosome segregation.
Akter M, Lyu X, Lu J, Wang X, Phonesavanh T, Wang H, Yu H, Kang J
The Journal of biological chemistry 2025 May;301(5):108464
The Journal of biological chemistry 2025 May;301(5):108464
The Role of PAX7 in Breast Cancer Prognosis and Its Mechanistic Involvement in the Wnt/β-Catenin Pathway.
Ge Q, Zhang W, Li C, Li X, Wang Z, Li X
Journal of cellular and molecular medicine 2025 May;29(10):e70602
Journal of cellular and molecular medicine 2025 May;29(10):e70602
PTPRG-AS1 regulates the KITLG/KIT pathway through the ceRNA axis to promote the malignant progression of gastric cancer and the intervention effect of Compound Kushen injection on it.
Wu C, Gao Y, Jin Z, Huang Z, Wang H, Lu S, Guo S, Zhang F, Zhang J, Huang J, Tao X, Liu X, Zhang X, You L, Li Q, Wu J
Pharmacological research 2025 May;215:107743
Pharmacological research 2025 May;215:107743
Paclitaxel alleviates spinal cord injury via activation of the Wnt/β-catenin signaling pathway.
Chen Z, Wo D, Wu C, Ma E, Peng J, Zhu W, Ren DN
Molecular medicine (Cambridge, Mass.) 2025 May 6;31(1):172
Molecular medicine (Cambridge, Mass.) 2025 May 6;31(1):172
Overexpression of c-Myc triggers p62 aggregation-mediated mitochondrial mitophagy in cabozantinib resistance of hepatocellular carcinoma.
Yang K, Zhang X, Yang K, Liu S, Zhang J, Fu Y, Liu T, Wu K, Li J, Liu C, Huang Q, Qu K
Molecular medicine (Cambridge, Mass.) 2025 May 27;31(1):209
Molecular medicine (Cambridge, Mass.) 2025 May 27;31(1):209
NOTCH1 inhibition enhances immunogenicity and sensitizes triple-negative breast cancer to immune checkpoint inhibitors.
Gao Y, Zuo L, Zheng Y, Sun K, Gao Y, Xu X, Li Z, Zuo D
Breast cancer research : BCR 2025 May 26;27(1):92
Breast cancer research : BCR 2025 May 26;27(1):92
NCOA5 induces sorafenib resistance in hepatocellular carcinoma by inhibiting ferroptosis.
Gao S, Fan L, Wang H, Wang A, Hu M, Zhang L, Sun G
Cell death discovery 2025 May 2;11(1):215
Cell death discovery 2025 May 2;11(1):215
Exploration of the pharmacological substance basis and efficacy evaluation of fufang she-she-cao (Hedyotis diffusa formula) in repressing gastric cancer.
Chen DH, Mao PJ, Diao WJ, Lu JQ, Wu SL, Li Q
Journal of ethnopharmacology 2025 May 12;347:119711
Journal of ethnopharmacology 2025 May 12;347:119711
HBV core protein enhances WDR46 stabilization to upregulate NUSAP1 and promote HCC progression.
Kong F, Bao E, Zhong Y, Wang Y, Liu R, Zhang H, Yang L, Jiang R, Liu X, Li C, Liu X, Pan X, Zheng K, You H, Tang R
Hepatology communications 2025 May 1;9(5)
Hepatology communications 2025 May 1;9(5)
Penta-1,4-dien-3-one and quinoxaline conjugates as potential anticancer agents via inhibiting EphB3/SRC/AKT axis.
Li Q, Zhou M, Yang Y, Jiang Y, Chen C, Hu E, Chen J, Wang D
Life sciences 2025 May 1;368:123510
Life sciences 2025 May 1;368:123510
Targeting ADAR1 with a small molecule for the treatment of prostate cancer.
Wang X, Li J, Zhu Y, Shen H, Ding J, Zeng T, Min W, Liang SQ, Huang L, Shi Z, Shen H, Huang F, Yuan K, Kuang W, Ji M, Sun C, Hou Y, Wang L, Chen W, Jiang Y, Hao H, Xiao Y, Yang P
Nature cancer 2025 Mar;6(3):474-492
Nature cancer 2025 Mar;6(3):474-492
CircXPO6 promotes breast cancer progression through competitively inhibiting the ubiquitination degradation of c-Myc.
Xu A, Li X, Cai Q, Yang C, Yang M, Gao H, Cheng M, Chen X, Ji F, Tang H, Wang K
Molecular and cellular biochemistry 2025 Mar;480(3):1731-1745
Molecular and cellular biochemistry 2025 Mar;480(3):1731-1745
Long Noncoding RNA E2F1 Messenger RNA Stabilizing Factor (EMS) Promotes Sorafenib Resistance in Renal Cell Carcinoma by Regulating miR-363-3p and Dual-Specificity Phosphatase 10 Expression.
Wang P, Deng Q, Pan S, Dong W
Journal of biochemical and molecular toxicology 2025 Mar;39(3):e70153
Journal of biochemical and molecular toxicology 2025 Mar;39(3):e70153
The MCM6-c-Myc positive feedback loop mediates bladder cancer progression and cisplatin resistance.
Wang J, Li X, Zhao L, Fan X, Cao J, Wang S, Li K, Wang H, Zhang Y, Wang H, Xu C, Ding L, Che T, Chen S, Yang L
International journal of biological macromolecules 2025 Mar;296:139777
International journal of biological macromolecules 2025 Mar;296:139777
Mechanism of β-Catenin in Pulmonary Fibrosis Following SARS-CoV-2 Infection.
Jiang M, Hou J, Chai Q, Yin S, Liu Q
Cells 2025 Mar 7;14(6)
Cells 2025 Mar 7;14(6)
Targeting NETO2 suppresses cell proliferation, invasion, and migration and inactivates the STAT3/C-MYC pathway in hepatocellular carcinoma.
He NSM, Wu X, Chen S, Yun X, Yao S, Yu H
World journal of surgical oncology 2025 Mar 29;23(1):107
World journal of surgical oncology 2025 Mar 29;23(1):107
ORMDL3 restrains type I interferon signaling and anti-tumor immunity by promoting RIG-I degradation.
Zeng Q, Yao C, Zhang S, Mao Y, Wang J, Wang Z, Sheng C, Chen S
eLife 2025 Mar 24;13
eLife 2025 Mar 24;13
Deletion of ENO1 sensitizes pancreatic cancer cells to gemcitabine via MYC/RRM1-mediated glycolysis.
Lu Y, Ma H, Xiong X, Du Y, Liu L, Wang J, Zhao W
Scientific reports 2025 Mar 22;15(1):9941
Scientific reports 2025 Mar 22;15(1):9941
CHI3L1: a key driver in gastritis-to-cancer transformation.
Li T, Jiang H, Gong Y, Liao M, Jia Y, Chen J, Dai M, Yan Y, Lu X, Chen R, Li Y, Chen Y, Lin J, Li Y, Ding X
Journal of translational medicine 2025 Mar 19;23(1):349
Journal of translational medicine 2025 Mar 19;23(1):349
Design of Selective BRD4 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease.
Yang Y, Liu H, Yuan H, Lyu K, Zhong H, Li Y, Cao D, Zhao W, Zhang H, Xiong B, Chen D, Guo D
Journal of medicinal chemistry 2025 Mar 13;68(5):5257-5274
Journal of medicinal chemistry 2025 Mar 13;68(5):5257-5274
TOP2A Promotes Proliferation, Migration, and Inflammatory Response in M5-Treated Keratinocytes by Binding CTBP1 to Activate Wnt/β-Catenin Signaling.
Yang Y, Liu S, Xiao X
Cell biochemistry and biophysics 2025 Jun;83(2):2101-2113
Cell biochemistry and biophysics 2025 Jun;83(2):2101-2113
Discovery of 5-imidazole-3-methylbenz[d]isoxazole derivatives as potent and selective CBP/p300 bromodomain inhibitors for the treatment of acute myeloid leukemia.
Hu JK, Tang X, Luo GL, Zhang C, Wu TB, Wang C, Shen H, Zhao XF, Wu XS, Smaill JB, Xu Y, Zhang Y, Xiang QP
Acta pharmacologica Sinica 2025 Jun;46(6):1706-1721
Acta pharmacologica Sinica 2025 Jun;46(6):1706-1721
A positive feedback loop of OTUD1 and c-Jun driven by leptin expedites stemness maintenance in ovarian cancer.
Wang J, Yang F, Chen Y, Xing Y, Huang J, Cao J, Xiong J, Liu Y, Zhao Q, Luo M, Xiong J, Fan G, Lyu Q, Li F, Zhang W
Oncogene 2025 Jun;44(22):1731-1745
Oncogene 2025 Jun;44(22):1731-1745
Targeting Myc through BET-PROTAC elicits potent anti-lymphoma activity in diffuse large B cell lymphoma.
Wang H, Wu X, Gao J, Chen S, Zhou Z, Zhang L, Liu B, Wei M
Investigational new drugs 2025 Jun;43(3):621-633
Investigational new drugs 2025 Jun;43(3):621-633
Interaction of osteopontin with α-lactalbumin and their synergistic effects in protecting intestinal barrier injury.
He W, Wang X, Zhang J, Cao H, Ren S, Sun X, Yu H, Zhang G, Li C, Liu L, Wang C, He J
Food research international (Ottawa, Ont.) 2025 Jun;211:116513
Food research international (Ottawa, Ont.) 2025 Jun;211:116513
Circovirus Rep evades immune restriction by disrupting cGAS oligomerization and phase separation.
Yin H, Zhao Z, Yuan Y, Li M, Chai L, Qu W, Ya Y, Wang H, Li X
PLoS pathogens 2025 Jun;21(6):e1013244
PLoS pathogens 2025 Jun;21(6):e1013244
SGLT2i delays c-Myc-induced HCC progression via targeting mTOR.
Rao H, An X, Qu X, Yu J, Xie J, Ke J, Liu Z, You L, Qiu Z, Tian L, Du W, Li W, Jia J, Liu D, Li S
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167805
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167805
Targeting the MDK/c-Myc complex to overcome temozolomide resistance in glioma.
Xi X, Ding X, Wang Q, Liu N, Wang B, Wang G, Zhong W, Lu Y
Clinical and translational medicine 2025 Jun;15(6):e70359
Clinical and translational medicine 2025 Jun;15(6):e70359
KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β-Catenin Signaling Pathway.
Hao Y, Zhang X, Ran S, Li Y, Ye W, Wang S, Li X, Luo Z, Zhao J, Zong J, Zheng K, Li R, Zhang H, Lai L, Huang P, Zou Z, Zhan W, Yue Z, Wu J, Xia J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2413964
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2413964
Duodenal Adenocarcinoma Is Characterized by Acidity, High Infiltration of Macrophage, and Activated Linc01559-GRSF1 Axis.
Huang X, Shi Y, Liu Z, Wu Y, Luo X, Chen D, Wei Z, Chen C, Ju H, Wu X, Liu X, Chen Z, Hu P
Biomedicines 2025 Jun 30;13(7)
Biomedicines 2025 Jun 30;13(7)
Serine/threonine/tyrosine kinase 1 drives pancreatic carcinogenesis via GSK3β sequestration-mediated Wnt/β-catenin pathway hyperactivation.
Zhou C, Dong X, Li S, Xi Y, Liu Y, Qian X, Song Z, Zhou L, Zhang R, Lyu H, Xiao S, Guo D, Zhang Q, Liu W, Xiong Y, Wang Z, Yan C, Zhang Z, Zhu H, Chen XZ, Song Z, Tang J
Signal transduction and targeted therapy 2025 Jun 30;10(1):205
Signal transduction and targeted therapy 2025 Jun 30;10(1):205
PGK1 phosphorylates NLRP3 and mediates inflammasome activation independent of its glycolytic activity.
Ma Z, Wu Y, Rao Z, Han C, Sun N, Li J, Zeng Q, Zhang Z, Ding D, Qiao J, Li W, Fang Y, Yang S, Li J, Zhang J, Chen Y
Cell reports 2025 Jun 24;44(6):115785
Cell reports 2025 Jun 24;44(6):115785
Cytohesin-4/ARF6 facilitates the progression of acute myeloid leukemia through activating PIK3R5/PI3K/AKT pathway.
Qiu XF, He CM, Zeng YM, Deng XL, Liang GL, Zhong MX, Zou M, Xiong XJ, Zhang JD, Ye Y, Niu Q, Chen XL
iScience 2025 Jun 20;28(6):112634
iScience 2025 Jun 20;28(6):112634
SLC3A2-Mediated Lysine Uptake by Cancer Cells Restricts T-cell Activity in Hepatocellular Carcinoma.
Chang Y, Wang N, Li S, Zhang J, Rao Y, Xu Z, Li L, Wu H, Chen J, Lin Y, Huang X, Liu P, Zhang J, Liao Y, Lin C, Huang C, Xia N
Cancer research 2025 Jun 16;85(12):2250-2267
Cancer research 2025 Jun 16;85(12):2250-2267
BRD9 promotes the malignant phenotype of thyroid cancer by activating the MAPK/ERK pathway.
Deng Y, Li Y, Cao H
Anti-cancer drugs 2025 Jun 1;36(5):359-373
Anti-cancer drugs 2025 Jun 1;36(5):359-373
Single-Cell and Spatial Transcriptomics Identified Fatty Acid-Binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension.
Liu B, Yi D, Li S, Ramirez K, Xia X, Cao Y, Zhao H, Tripathi A, Qiu S, Kala M, Rafikov R, Gu H, de Jesus Perez V, Lemay SE, Glembotski CC, Knox KS, Bonnet S, Kalinichenko VV, Zhao YY, Fallon MB, Boucherat O, Dai Z
Arteriosclerosis, thrombosis, and vascular biology 2025 Jul;45(7):1145-1165
Arteriosclerosis, thrombosis, and vascular biology 2025 Jul;45(7):1145-1165
Chronic prostatitis/chronic pelvic pain syndrome impairs erectile function by inducing apoptosis in a rat model of experimental autoimmune prostatitis.
Gu Q, Luan J, Yu M, Xia J, Wang Z
International journal of impotence research 2025 Jul;37(7):519-526
International journal of impotence research 2025 Jul;37(7):519-526
HBx Drives Liver Cancer Stem Cell Generation Through Stimulating Glucose Metabolic Reprogramming.
Liu J, Wu X, Yin Q, Zhang L, Liu K, Huang K, Xu J, Li X, Lin B, Zhu M, Li M
Journal of cellular and molecular medicine 2025 Jul;29(14):e70722
Journal of cellular and molecular medicine 2025 Jul;29(14):e70722
MTMR regulates KRAS function by controlling plasma membrane levels of phospholipids.
Lange TE, Naji A, van der Hoeven R, Liang H, Zhou Y, Hammond GRV, Hancock JF, Cho KJ
The Journal of cell biology 2025 Jul 7;224(7)
The Journal of cell biology 2025 Jul 7;224(7)
The scaffold protein DLG4 facilitates RNF63-mediated ubiquitination and degradation of STAT3 in non-small cell lung cancer.
Chen S, Xu H, Li N, Yang Y, Pang R, Zhang S, Qiao J, Chen H
Cell communication and signaling : CCS 2025 Jul 6;23(1):325
Cell communication and signaling : CCS 2025 Jul 6;23(1):325
Metabolomics and proteomics reveal blocking argininosuccinate synthetase 1 alleviates colitis in mice.
Liu S, Sun H, Du Z, Lu S, Wang C, Zhang Y, Luo Z, Wang L, Fan Z, Wei P, Yan Y, Zhang J, Yin S, Liu T, He Q, Guo X, Ding K, Zhou J, Hua H, Yu C, Xu W, Shan J, Li Y, Xu Y, Shen X, Cao G, Zhou W
Nature communications 2025 Jul 30;16(1):6983
Nature communications 2025 Jul 30;16(1):6983
Genetic modulation of lncPSMB1 confers non-syndromic cleft lip with or without cleft palate susceptibility by promoting cell apoptosis.
Li X, Gao Y, Cheng T, Lin J, Lou S, Wang L, Mi C, Ding X, Du M, Pan Y
Communications biology 2025 Jul 29;8(1):1123
Communications biology 2025 Jul 29;8(1):1123
Design, Synthesis, and Activity Evaluation of Novel Nucleosides as ADAR1 Inhibitor for the Treatment of Prostate Cancer.
Zhu Y, Shen H, Ding J, Wang M, Ji J, Hou Y, Cai Z, Li J, Chen W, Kuang W, Wang L, Min W, Yang P, Wang X
Journal of medicinal chemistry 2025 Jul 24;68(14):14495-14513
Journal of medicinal chemistry 2025 Jul 24;68(14):14495-14513
Modulatory Effect of Curcumin on Expression of Methyltransferase/Demethylase in Colon Cancer Cells: Impact on wt p53, mutp53 and c-Myc.
Santarelli R, Di Dio C, Di Crosta M, Currà P, Gonnella R, Cirone M
Molecules (Basel, Switzerland) 2025 Jul 22;30(15)
Molecules (Basel, Switzerland) 2025 Jul 22;30(15)
Keratin 6A Overexpression in the Lymphovascular Invasion-Associated Tumor Subgroup Promotes Progression of Triple-Negative Breast Cancer.
Luo W, Zou Y, Jiang Y, Ma X, Guo S, Wang Y, Liu Y, Hai L, Jia W, Liu W, Meng R, Cao X, Ruan X, Yu Y
Cancer research and treatment 2025 Jul 14;
Cancer research and treatment 2025 Jul 14;
SOX2 is a dispensable modulator of NUT carcinoma oncogenesis in mouse.
Luo C, Zheng D, Elnegiry A, Bhatara S, Mias GI, Tsoi MF, Yu J, Gu B
bioRxiv : the preprint server for biology 2025 Jul 14;
bioRxiv : the preprint server for biology 2025 Jul 14;
Sialidase NEU3 silencing inhibits angiogenesis of EA.hy926 cells by regulating Wnt/β-catenin signaling pathway.
Wu Y, Yuan X, Zhang Y, Ma F, Zhao W, Sun X, Ma X, Chen Y
Biochemical and biophysical research communications 2025 Jan;742:151098
Biochemical and biophysical research communications 2025 Jan;742:151098
Inhibiting the Otub1/phosphorylated STAT3 axis for the treatment of non-small cell lung cancer.
Liu ZY, Zhang YW, Zhuang HX, Ou YJ, Jiang QY, Li PF, He YM, Ren Y, Mao XL
Acta pharmacologica Sinica 2025 Jan;46(1):184-195
Acta pharmacologica Sinica 2025 Jan;46(1):184-195
A peptide encoded by LINC00944 suppresses the growth of melanoma cells by diminishing EP400-MYC interaction.
Ren Z, Liu J, Chang X, Yang X, Zhang Y, Zhang X, Zhou S, Liang Q, Xu Z, Yang F, Xiao W
Biochemical pharmacology 2025 Jan;231:116652
Biochemical pharmacology 2025 Jan;231:116652
CqProfilin enhances WSSV infection by promoting viral intracellular transport through binding to both viral nucleocapsid and actin cytoskeleton.
Li DL, Wu WL, Liu HP
Developmental and comparative immunology 2025 Jan;162:105281
Developmental and comparative immunology 2025 Jan;162:105281
IRAK2 overexpression restrains prostate cancer progression by regulation of TRAF6 ubiquitination.
Shi Y, Wu C, Wang C, Shen Y, Jiang A, Cao K, Liu X, Jiang X, Lv Z
Cellular signalling 2025 Jan;125:111508
Cellular signalling 2025 Jan;125:111508
FAM49B drives colorectal cancer progression by stabilizing c-Myc through NEK9 phosphorylation.
Lu C, Liu T, Yimin E, Miao L, Yu C, Zhang J, Luo X
BioFactors (Oxford, England) 2025 Jan-Feb;51(1):e2158
BioFactors (Oxford, England) 2025 Jan-Feb;51(1):e2158
Elevated-c-MYC-expressing Fibrosarcoma Cells With Acquired Gemcitabine Resistance Remain Sensitive to Recombinant Methioninase: A Potential Clinical Strategy for a Recalcitrant Disease.
Morinaga S, Han Q, Mizuta K, Kang BM, Bouvet M, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Higuchi T, Tsuchiya H, Demura S, Hoffman RM
Cancer diagnosis & prognosis 2025 Jan-Feb;5(1):8-14
Cancer diagnosis & prognosis 2025 Jan-Feb;5(1):8-14
LRP11 facilitates lipid metabolism and malignancy in hepatocellular carcinoma by stabilizing RACK1 through USP5 regulation.
Liang L, Jia W, Wang J, Feng Y, Zhu D, Zhao W, Xu C, Ling X, Lv Q, Ai X, Kong L, Ding W
Molecular medicine (Cambridge, Mass.) 2025 Jan 31;31(1):35
Molecular medicine (Cambridge, Mass.) 2025 Jan 31;31(1):35
Jiedu Xiaozheng Yin extract targets cancer stem cells by Wnt signaling pathway in colorectal cancer.
Feng H, Yang Y, Chen H, Zhang Z, Zeng J, Huang Y, Yang X, Yang L, Du J, Cao Z
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118710
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118710
CASC8 activates the pentose phosphate pathway to inhibit disulfidptosis in pancreatic ductal adenocarcinoma though the c-Myc-GLUT1 axis.
Yao HF, Ge J, Chen J, Tang X, Li C, Hu X, Ahmed AA, Pu Y, Zhou G, Zhang T, Cai Z, Jiang C
Journal of experimental & clinical cancer research : CR 2025 Jan 27;44(1):26
Journal of experimental & clinical cancer research : CR 2025 Jan 27;44(1):26
Bletilla striata polysaccharide-mediated trained immunity drives the hematopoietic progenitors' expansion and myelopoiesis.
Zhang J, Zhong C, Chen L, Luo Y, Tang L, Yang J, Jia J, Xie X, Liu P, Yu J, Cui Y
International immunopharmacology 2025 Jan 27;146:113909
International immunopharmacology 2025 Jan 27;146:113909
Ubiquitin-conjugating enzyme E2T confers chemoresistance of colorectal cancer by enhancing the signal propagation of Wnt/β-catenin pathway in an ERK-dependent manner.
Liu B, Liu R, Zhang X, Tian L, Li Z, Yu J
Chemico-biological interactions 2025 Jan 25;406:111347
Chemico-biological interactions 2025 Jan 25;406:111347
Targeted Degradation of HCV Polymerase by GalNAc-Conjugated ApTACs for Pan-Genotypic Antiviral Therapy with High Resistance Barriers.
Pan W, Wu S, Zhou H, Xia Y, Li Q, Ge R, Wu J, Han H, Chen S, Li Y, Li J, Chen M, Liu M, Zhou J, Xie S
Journal of medicinal chemistry 2025 Jan 23;68(2):1473-1482
Journal of medicinal chemistry 2025 Jan 23;68(2):1473-1482
Structure-Based Rational Design and Evaluation of BET-Aurora Kinase Dual-Inhibitors for Treatment of Cancers.
Lyu K, Ren Y, Mou J, Yang Y, Pan Y, Zhang H, Li Y, Cao D, Chen L, Chen D, Guo D, Xiong B
Journal of medicinal chemistry 2025 Jan 23;68(2):1344-1364
Journal of medicinal chemistry 2025 Jan 23;68(2):1344-1364
miR-28-3p suppresses gastric cancer growth and EMT-driven metastasis by targeting the ARF6/Hedgehog axis.
Ji H, Liu S, Yang L, Wu Y, Zhang H, Liu X, Li L, Li L
Molecular and cellular probes 2025 Feb;79:102010
Molecular and cellular probes 2025 Feb;79:102010
NEK2 Promotes ESCC Malignant Progression by Inhibiting Cellular Senescence via the FOXM1/c-Myc/p27 Signaling Pathway.
Li J, Wang Y, Wei S, Xu S, Dai S, Zhang L, Tian Z, Zhao L, Lv H
Molecular carcinogenesis 2025 Feb;64(2):244-259
Molecular carcinogenesis 2025 Feb;64(2):244-259
β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis.
Zhang Y, Zhu X, Chen L, Gao T, Chen G, Zhu J, Wang G, Zuo D
Neoplasia (New York, N.Y.) 2025 Feb;60:101096
Neoplasia (New York, N.Y.) 2025 Feb;60:101096
METTL5 Promotes Tumor Progression in Oral Squamous Cell Carcinoma by Activating the Myc Pathway.
Huang R, Feng X, Zhou T, Lu J, Wang Y, Zhang S, Zhang W
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2025 Feb;54(2):91-99
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2025 Feb;54(2):91-99
ZIP8 Regulates Inflammation and Macrophage Polarisation in Intervertebral Disc Degeneration via the Wnt/β-Catenin Pathway.
Xu J, Gu H, Zhou K, Wu L, Zhang Y, Bian C, Huang Z, Chen G, Cheng X, Yin X
Journal of cellular and molecular medicine 2025 Feb;29(4):e70431
Journal of cellular and molecular medicine 2025 Feb;29(4):e70431
Enhanced Oxidative Phosphorylation Driven by TACO1 Mitochondrial Translocation Promotes Stemness and Cisplatin Resistance in Bladder Cancer.
Deng M, Zhou Z, Chen J, Li X, Liu Z, Ye J, Wei W, Wang N, Peng Y, Luo X, Jiang L, Zhou F, Zheng X, Liu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2408599
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2408599
PNPO-Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β-Catenin Pathway.
Deng Z, Sun S, Zhou N, Peng Y, Cheng L, Yu X, Yuan Y, Guo M, Xu M, Cheng Y, Zhou F, Li N, Yang Y, Gu C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2407681
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2407681
PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53.
Fan Y, Li Y, Luo X, Xiang S, Hu J, Zhan J, Chang W, Deng R, Ran X, Zhang Y, Cai Y, Zhu W, Wang H, Liu Z, Wang D
Journal of translational medicine 2025 Feb 4;23(1):157
Journal of translational medicine 2025 Feb 4;23(1):157
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Wang M, Yang S, Li X, Zheng Y, Bai Y, Luo W, Zhu G, Chang J, Zhu B
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
SJB2-043, a USP1 Inhibitor, Suppresses A549 Cell Proliferation, Migration, and EMT via Modulation of PI3K/AKT/mTOR, MAPK, and Wnt Signaling Pathways.
Wu L, Yu M, Liang H, Lin L, Li H, Chen G, Muhetaer H, Li J, Wu B, Jia X, Dang Y, Zheng G, Li C
Current issues in molecular biology 2025 Feb 27;47(3)
Current issues in molecular biology 2025 Feb 27;47(3)
Overexpressed NEK2 contributes to progression and cisplatin resistance through activating the Wnt/β-catenin signaling pathway in cervical cancer.
Haiye J, Xiangzhu W, Yunfei Z, Shumin G, Chang N, Yaohui J, Heng Y, Xinmin N
Cancer cell international 2025 Feb 14;25(1):45
Cancer cell international 2025 Feb 14;25(1):45
A novel 5'tRNA-derived fragment tRF-Tyr inhibits tumor progression by targeting hnRNPD in gastric cancer.
Cui H, Liu Z, Peng L, Liu L, Xie X, Zhang Y, Gao Z, Zhang C, Yu X, Hu Y, Liu J, Shang L, Li L
Cell communication and signaling : CCS 2025 Feb 14;23(1):88
Cell communication and signaling : CCS 2025 Feb 14;23(1):88
Unraveling the miR-144-3p/PUMA pathway: a novel regulator of FDX1-mediated cuproptosis in colorectal cancer.
Jia G, Li J, Jiang M, Liu N, Ding N, Jiang X, Zhang G, Tan X, Kang Y, Zhang L, Wang F, Zhang Y
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1693-1710
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1693-1710
Pan-cancer analysis identifies adhesion G protein-coupled receptor G6 as a potential prognostic and immunotherapeutic biomarker with its functional validation.
Zhu J, Wang Y, Huang Q, Liu Z
International journal of biological macromolecules 2025 Dec;334(Pt 2):149128
International journal of biological macromolecules 2025 Dec;334(Pt 2):149128
Targeting TRAF6 inhibits cystogenesis in autosomal dominant polycystic kidney disease.
Ren Y, Pan Y, Zhu X, Li L, Zhao W, Fu K, Chen Y, Sun Y, Guo D
Biochemical pharmacology 2025 Dec;242(Pt 2):117222
Biochemical pharmacology 2025 Dec;242(Pt 2):117222
Terpine-4-ol alleviates lipopolysaccharide-induced intestinal injury in weaned piglets by regulating intestinal epithelial cell homeostasis via the Wnt/β-catenin signaling pathway.
Dong L, Zhou Y, Wang M, Yuan Q, Qiu G, Liu J, Wang H, Wu A, Yu L, Chen D
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Dec;23:178-190
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Dec;23:178-190
A novel lncRNA, Lnc21q22.11, suppresses gastric cancer growth by inhibiting MEK/ERK pathway.
Zhu C, Zhang M, Yang W, Gao A, Yu X, Su X, Chen R, Guo M
Epigenetics 2025 Dec;20(1):2512764
Epigenetics 2025 Dec;20(1):2512764
N2 neutrophils induce cell stemness reprogramming to promote gastric cancer progression via exosomal miRNAs.
Tang H, Zhong Y, Wang J, Meng S, Yu D, Fan B, Dong X, Wang M, Fu M, Qian Y, Zhang X, Ji R, Zhang X, Fang X, Zhang J
Cellular signalling 2025 Dec;136:112085
Cellular signalling 2025 Dec;136:112085
Multi-omics analysis reveals that ALYREF-mediated m(5)C modification promotes platinum resistance in ovarian cancer via the NSUN2/ALYREF/LGR4 axis.
Yang S, He P, Wang W, Xu X, Xi X, Li Y
Cell death & disease 2025 Dec 5;17(1):77
Cell death & disease 2025 Dec 5;17(1):77
LGR5 interacts with HSP90AB1 to mediate enzalutamide resistance by activating the WNT/β-catenin/AR axis in prostate cancer.
Gao Z, Xiong Z, Tao Y, Wang Q, Guo K, Xu K, Huang H
Chinese medical journal 2025 Dec 5;138(23):3184-3194
Chinese medical journal 2025 Dec 5;138(23):3184-3194
Bruceine D promotes TNBC regression by inhibiting M2-like tumor-associated macrophage polarization induced Wnt3a/β-catenin pathway.
Ma Y, Cao D, Han X, Hu Z, Ding X, Wang J
International immunopharmacology 2025 Dec 3;166:115596
International immunopharmacology 2025 Dec 3;166:115596
EXOSC3 knockdown induces G1/S phase arrest to suppress hepatocellular carcinoma cell proliferation.
Chen YM, Huo YX, Wei WS, Liu YX, Wang SH, Jiang L, Rong-He, Zhang HL, Jiang LH
Scientific reports 2025 Dec 29;15(1):44684
Scientific reports 2025 Dec 29;15(1):44684
piR-hsa-022095 Drives Hypertrophic Scar Formation via KLF11-Dependent Fibroblast Proliferation.
Ren R, Qian W, Zhao H, Wang D, Xiao Y, Lin Y
Biomedicines 2025 Dec 2;13(12)
Biomedicines 2025 Dec 2;13(12)
Aurora A degradation by HSP90 interactome-mediating PROTACs in A549 and paclitaxel-resistant A549 cells.
Deng XY, Xu H, Peng YX, Guo YY, He RF, Lu G
European journal of medicinal chemistry 2025 Dec 15;300:118141
European journal of medicinal chemistry 2025 Dec 15;300:118141
CUL4B promotes hepatocellular carcinoma progression and oxaliplatin resistance by facilitating FUS degradation.
Wei JD, Cheng K, Wu X, Zhang L, Wang Q, Liang Y, Zhu Z, Meng W, Chen W, Guan X, Yang H, Zhou L
Cell death & disease 2025 Dec 14;17(1):116
Cell death & disease 2025 Dec 14;17(1):116
THOC1 binds to U2AF2 and regulates ovarian cancer progression through the beta-catenin / c-myc / cyclinD1 signaling pathway.
Feng Y, Liu J, Zhang S, Zhang Z, Zhang D, Cao Y, Li M
Cancer cell international 2025 Dec 11;26(1):17
Cancer cell international 2025 Dec 11;26(1):17
Machine learning-based identification of kbhb-affected tumor cell subsets as prognostic and therapeutic targets in breast cancer.
Yuan Q, Sha Y, Ye R, Yu H, Ni L, Han J, Deng L
Journal of translational medicine 2025 Dec 11;24(1):71
Journal of translational medicine 2025 Dec 11;24(1):71
Repetitive unidirectional spinal tactile stimulation engages microglial Bmal1 pathways to promote synaptic remodeling in the mPFC of adolescent VPA-exposed mice.
Chen YN, Zhao ST, Hu MA, Li W, Yu J, Ma MJ, Tang LY, Feng X, Li JS, Zhang YX
Journal of neuroinflammation 2025 Dec 11;23(1):23
Journal of neuroinflammation 2025 Dec 11;23(1):23
METTL1-driven epitranscriptomic enhancement of TXNDC12 boosts c-Myc stability through USP5 in HNSCC.
Mai Z, Zheng J, Lu Y, Lin P, Lin Y, Zheng Y, Chen X, Guo B, Cui L, Zhao X
Experimental & molecular medicine 2025 Aug;57(8):1743-1758
Experimental & molecular medicine 2025 Aug;57(8):1743-1758
Dujieqing decoction suppresses multiple myeloma growth by inhibiting the Wnt/β-catenin pathway.
Jiawei XU, Haisong LU, Yushi S, Yu L, Xueping LI, Weimin C
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Aug;45(4):720-729
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Aug;45(4):720-729
Inhibition of UCH-L1 enhances immunotherapy efficacy in triple-negative breast cancer by stabilizing PD-L1.
He L, He J, Jiang T, Gong R, Wan X, Duan M, Chen Z, Cheng Y
European journal of pharmacology 2025 Aug 5;1000:177743
European journal of pharmacology 2025 Aug 5;1000:177743
Extrachromosomal DNA biogenesis is dependent on DNA looping and religation by YY1-Lig3-PARylation complex.
Qin LN, Wu T, Zhen XT, Zhao YL, Zhou JS, Cheng SB, Wang KW, Qiao S, Huang DZ, Zhang H, Sun T
Molecular cell 2025 Aug 21;85(16):3090-3107.e11
Molecular cell 2025 Aug 21;85(16):3090-3107.e11
Drug-Free Approach to Regulate Undruggable Proto-Oncogene MYC Using Biomimetic Porous Nanoparticles for Cancer Immunotherapy.
Happonen E, Dang Y, Wang J, Saarela S, Sivonen M, Zakir M, Laari MI, Constantinou Y, Tamarov K, Hakkarainen H, Montaser AB, Leinonen H, Küblbeck J, Örd T, Taipale M, Kaikkonen M, Liu R, Klefström J, Yu H, Xu Z, Lehto VP, Xu W
ACS applied materials & interfaces 2025 Aug 20;17(33):46521-46534
ACS applied materials & interfaces 2025 Aug 20;17(33):46521-46534
ICAM-1-mediated Src signaling pathway plays a pivotal role in encephalomyocarditis virus entry.
Lian R, Dou X, Wang N, Li S, Xie J, Li X, Yang Y, Wen Y, Li H, Feng R
Journal of virology 2025 Aug 19;99(8):e0071525
Journal of virology 2025 Aug 19;99(8):e0071525
CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability.
He C, Tang C, Guo J, Yin X, Zhu Q, Fang C
Journal of translational medicine 2025 Aug 19;23(1):939
Journal of translational medicine 2025 Aug 19;23(1):939
Resveratrol induces ferroptosis in triple-negative breast cancer through NEDD4L-mediated GPX4 ubiquitination and degradation.
Zhang E, Wang Y, Zhang H, Li X, Su Y, Cui J, Xu R, Mao X, Sang M, Lin Z, Zhou X
Free radical biology & medicine 2025 Aug 1;235:231-247
Free radical biology & medicine 2025 Aug 1;235:231-247
Investigating the Mechanism of IFN-γ-Inducible Lysosomal Thiol Reductase-Mediated Inhibition of Breast Cancer Cell Proliferation.
Liu Q, Yuan X, Shao Y, Guan X, Feng K, Chu M, Chen L, Li H, Liu H, Zhang J, Tian Y, Wei L
Cancer innovation 2025 Apr;4(2):e161
Cancer innovation 2025 Apr;4(2):e161
PLEKHA4 knockdown induces apoptosis in melanoma cells through the MAPK and β‑catenin signaling pathways.
Yue Y, An G, Cao S, Li X, Du L, Xu D, Liu L
Molecular medicine reports 2025 Apr;31(4)
Molecular medicine reports 2025 Apr;31(4)
N6-methyladenosine-mediated EIF3H promotes anaplastic thyroid cancer progression and ferroptosis resistance by stabilizing β-catenin.
Zhang Z, Zhou D, Qiu X, Xia F, Li X
Free radical biology & medicine 2025 Apr;231:38-47
Free radical biology & medicine 2025 Apr;231:38-47
Shengjiang Xiexin Decoction ameliorates DSS-induced ulcerative colitis via activating Wnt/β-Catenin signaling to enhance epithelium renovation and modulating intestinal flora.
Chen C, Lin XH, Xie YM, Xiong SL, Hou SZ, Huang S, Jian HL, Wen YF, Jiang XY, Liang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156456
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156456
Targeting the Adenosine-Mediated Metabolic Immune Checkpoint with Engineered Probiotic for Enhanced Chemo-Immunotherapy.
Wang J, Wang J, Yu Z, Wen H, Zhao C, Zhong J, Xiao C, Li Y, Xu J, Wang J, Mao ZW, Xia W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2411813
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2411813
Nuclear to Cytoplasmic Transport Is a Druggable Dependency in HDAC7-driven Small Cell Lung Cancer.
Qin T, Wang J, Wang J, Du Q, Wang L, Liu H, Liu W, Li X, Jiang Y, Xu Q, Yu J, Liu H, Wang T, Li M, Huang D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413445
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413445
Cannabidiol Enhances the Anticancer Activity of Etoposide on Prostate Cancer Cells.
Erzurumlu Y, Catakli D
Cannabis and cannabinoid research 2025 Apr;10(2):258-276
Cannabis and cannabinoid research 2025 Apr;10(2):258-276
Endothelial USP11 drives VEGFR2 signaling and angiogenesis via PRDX2/c-MYC axis.
Chen C, Chen Z, Luo R, Tu W, Long M, Liang M, Cheng M, Wang Z, Huang K, Wang C
Angiogenesis 2025 Apr 8;28(2):23
Angiogenesis 2025 Apr 8;28(2):23
Modulation of Intestinal Barrier Function and Wnt/β- Catenin Pathway by Sanzi Formula in Colorectal Adenoma Development.
Peng W, Li Z, Zou S, Li H, Tian Y, Hua Y, Wei L, Zhang Z, Gu Y, Xu T
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2025 Apr 7;36(9):547-555
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2025 Apr 7;36(9):547-555
Development of Novel PRMT7 Inhibitors for the Treatment of Prostate Cancer.
Li J, Sun C, Zhang Y, Ding J, Yao P, Shen H, Shi Z, Wang W, Zhu Y, Kuang W, Tavus A, Wang L, Yuan K, Wang X, Yang P
Journal of medicinal chemistry 2025 Apr 24;68(8):8244-8268
Journal of medicinal chemistry 2025 Apr 24;68(8):8244-8268
PRMT5-mediated methylation of METTL3 promotes cisplatin resistance in ovarian cancer by facilitating DNA repair mechanisms.
Xia Q, Zhong R, Zheng J, Zhou X, Zhao X, Wang S, Wang B, Wu Q, Xie C, Kong B, Zhang Q, Huang T
Cell reports 2025 Apr 22;44(4):115484
Cell reports 2025 Apr 22;44(4):115484
The role of IGF2BP3/SPOP/c-Myc loop in paclitaxel resistance of endometrial cancer.
Ge Y, Kong L, Li Y, Yu Z, Zhai F, Zhan Z, Chen G, Wang S, Wang H, Wang Y, Zhao J, Hu L, Mao J, Wang S, Shi J, Zhao M, Lou P, Ye M, Jin X
Communications biology 2025 Apr 17;8(1):624
Communications biology 2025 Apr 17;8(1):624
Porcine reproductive and respiratory syndrome virus nsp5 inhibits the activation of the Nrf2/HO-1 pathway by targeting p62 to antagonize its antiviral activity.
Wang F, Amona FM, Pang Y, Zhang Q, Liang Y, Chen X, Ke Y, Chen J, Song C, Wang Y, Li Z, Zhang C, Fang X, Chen X
Journal of virology 2025 Apr 15;99(4):e0158524
Journal of virology 2025 Apr 15;99(4):e0158524
LINC02167 stabilizes KSR1 mRNA in an m(5)C-dependent manner to regulate the ERK/MAPK signaling pathway and promotes colorectal cancer metastasis.
Qi J, Jiang T, Liu B, Hu Q, Chen J, Ma N, Xu Y, Song H, Song J
Journal of experimental & clinical cancer research : CR 2025 Apr 15;44(1):121
Journal of experimental & clinical cancer research : CR 2025 Apr 15;44(1):121
The dual HDAC/PI3K inhibitor CUDC-907 inhibits the growth and proliferation of MYC-driven Group 3 medulloblastoma.
Gou P, Fang C, Xu M, Zhang D, Wu X, Zhang L, Li X, Li M, Gan L, Luo J, Cui H, Liang P
Cell death discovery 2025 Apr 14;11(1):172
Cell death discovery 2025 Apr 14;11(1):172
Astragaloside IV Ameliorates Colonic Adenomatous Polyps Development by Orchestrating Gut Bifidobacterium and Serum Metabolome.
Wen LP, Gao SW, Chen HX, Liu Q, Xiao GZ, Lin HC, He QL
The American journal of Chinese medicine 2024;52(5):1527-1554
The American journal of Chinese medicine 2024;52(5):1527-1554
IL13RA2 promotes progression of infantile haemangioma by activating glycolysis and the Wnt/β-catenin signaling pathway.
Liu Z, Ma T, Li J, Ren W, Zhang Z
Oncology research 2024;32(9):1453-1465
Oncology research 2024;32(9):1453-1465
The m6A modification-mediated positive feedback between glycolytic lncRNA SLC2A1-DT and c-Myc promotes tumorigenesis of hepatocellular carcinoma.
Zeng Z, Wang J, Xu F, Hu P, Hu Y, Zhuo W, Chen D, Han S, Wang F, Zhao Y, Huang Y, Zhao G
International journal of biological sciences 2024;20(5):1744-1762
International journal of biological sciences 2024;20(5):1744-1762
VEGFA/NRP-1/GAPVD1 axis promotes progression and cancer stemness of triple-negative breast cancer by enhancing tumor cell-macrophage crosstalk.
Wang L, Zhang L, Zhao L, Shao S, Ning Q, Jing X, Zhang Y, Zhao F, Liu X, Gu S, Zhao X, Luo M
International journal of biological sciences 2024;20(2):446-463
International journal of biological sciences 2024;20(2):446-463
MPP7 mediates EMT via Wnt/β-catenin pathway to promote polarity changes in epithelial ovarian cancer cells.
Tao C, Ni X
Journal of Cancer 2024;15(14):4490-4502
Journal of Cancer 2024;15(14):4490-4502
African swine fever virus structural protein p17 inhibits IRF3 activation by recruiting host protein PR65A and inducing apoptotic degradation of STING.
Wang S, Xiang Z, Gao P, Zhang Y, Zhou L, Ge X, Guo X, Han J, Yang H
Frontiers in microbiology 2024;15:1428233
Frontiers in microbiology 2024;15:1428233
Chidamide represses MYC expression and might improve survival for patients with double expressor lymphoma.
Liu P, Hang X, Li J, Zhao L, Liu W, Ji J, Wu Y, Wan X, Shuai X, Guo Y, Xiang B, Liu J, Huang J, Liu Z, Hou L, Chen C, Liu Y, Liu T
American journal of cancer research 2024;14(6):2921-2933
American journal of cancer research 2024;14(6):2921-2933
High glucose-induced NCAPD2 upregulation promotes malignant phenotypes and regulates EMT via the Wnt/β-catenin signaling pathway in HCC.
Mai Y, Liao C, Wang S, Zhou X, Meng L, Chen C, Qin Y, Deng G
American journal of cancer research 2024;14(4):1685-1711
American journal of cancer research 2024;14(4):1685-1711
Anillin contributes to prostate cancer progression through the regulation of IGF2BP1 to promote c-Myc and MAPK signaling.
Liu J, Wang S, Zhang C, Wei Z, Han D, Song Y, Song X, Chao F, Wu Z, Xu G, Chen G
American journal of cancer research 2024;14(2):490-506
American journal of cancer research 2024;14(2):490-506
Comprehensive analysis of ferroptosis-related genes indicates that TRIM46 is a novel biomarker and promotes the progression of ovarian cancer via modulating ferroptosis and Wnt signaling pathway.
Liu S, Xiao C, Rong Y, Liu M, Yang K, Tang J, Wang Z
American journal of cancer research 2024;14(10):4686-4707
American journal of cancer research 2024;14(10):4686-4707
The role of VANGL2 in glioma oncogenesis and progression: insights into expression profiles and prognostic relevance.
Zhao M, Chen S
Frontiers in oncology 2024;14:1527226
Frontiers in oncology 2024;14:1527226
Vitamin D-metabolizing enzyme CYP24A1 affects oncogenic behaviors of oral squamous cell carcinoma and its prognostic implication.
Nakamori Y, Takasawa A, Takasawa K, Kyuno D, Ono Y, Magara K, Nakahashi N, Sekiguchi S, Tsuchihashi K, Miyazaki A, Osanai M
Medical molecular morphology 2024 Sep;57(3):185-199
Medical molecular morphology 2024 Sep;57(3):185-199
Novel circular RNA hsa_circ_0036683 suppresses proliferation and migration by mediating the miR-4664-3p/CDK2AP2 axis in non-small cell lung cancer.
Liu R, Zhang H, Xin J, Xie SY, Jiao F, Li YJ, Chu MY, Qiu J, Yan YF
Thoracic cancer 2024 Sep;15(27):1929-1945
Thoracic cancer 2024 Sep;15(27):1929-1945
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation.
Zhou J, Zhang L, Peng J, Zhang X, Zhang F, Wu Y, Huang A, Du F, Liao Y, He Y, Xie Y, Gu L, Kuang C, Ou W, Xie M, Tu T, Pang J, Zhang D, Guo K, Feng Y, Yin S, Cao Y, Li T, Jiang Y
Cell metabolism 2024 Sep 3;36(9):2054-2068.e14
Cell metabolism 2024 Sep 3;36(9):2054-2068.e14
Novel potent molecular glue degraders against broad range of hematological cancer cell lines via multiple neosubstrates degradation.
Li P, Hu X, Fan Z, Sun S, Ran Q, Wei T, Wei P, Jiang Q, Yan J, Yang N, Jia C, Yang T, Mao Y, Cai X, Xu T, Zhao Z, Qian X, Qin W, Zhuang X, Fan F, Xiao J, Zheng Z, Li S
Journal of hematology & oncology 2024 Sep 2;17(1):77
Journal of hematology & oncology 2024 Sep 2;17(1):77
ARMCX1 inhibits lung adenocarcinoma progression by recruiting FBXW7 for c-Myc degradation.
Hu Z, Wu Y, Sun X, Tong Y, Qiu H, Zhuo E
Biology direct 2024 Sep 16;19(1):82
Biology direct 2024 Sep 16;19(1):82
Study on the mechanism of macrophages activated by phosphoesterified rehmanniae polysaccharide on human gastric cancer cells.
Liu X, Yang F, Ren P, Lv W, Chen B, Niu B, Ren Y, Wang L, Sun M, Zuo Z, Li J, Geng A
International journal of biological macromolecules 2024 Oct;277(Pt 1):133952
International journal of biological macromolecules 2024 Oct;277(Pt 1):133952
Targeting SNAI1-Mediated Colorectal Cancer Chemoresistance and Stemness by Sphingosine Kinase 2 Inhibition.
Janakiraman H, Gao Z, Zhu Y, Dong J, Becker SA, Janneh A, Ogretmen B, Camp ER
World journal of oncology 2024 Oct;15(5):744-757
World journal of oncology 2024 Oct;15(5):744-757
N-acetylgalactosaminyltransferase GALNT6 is a potential therapeutic target of clear cell renal cell carcinoma progression.
Sun L, Li Z, Shu P, Lu M
Cancer science 2024 Oct;115(10):3320-3332
Cancer science 2024 Oct;115(10):3320-3332
CHAC1 blockade suppresses progression of lung adenocarcinoma by interfering with glucose metabolism via hijacking PKM2 nuclear translocation.
Pan J, Wu S, Pan Q, Zhang Y, He L, Yao Q, Chen J, Li J, Xu Y
Cell death & disease 2024 Oct 5;15(10):728
Cell death & disease 2024 Oct 5;15(10):728
RHOF promotes Snail1 lactylation by enhancing PKM2-mediated glycolysis to induce pancreatic cancer cell endothelial-mesenchymal transition.
Zhao R, Yi Y, Liu H, Xu J, Chen S, Wu D, Wang L, Li F
Cancer & metabolism 2024 Oct 26;12(1):32
Cancer & metabolism 2024 Oct 26;12(1):32
Inhibition of UBE2N in regulatory T-cells boosts immunity against cancer.
Miao W, Jain V, Han M, Jin YJ, Beasley GM, Starczysnowski DT, Gregory SG, Zhang JY
bioRxiv : the preprint server for biology 2024 Oct 25;
bioRxiv : the preprint server for biology 2024 Oct 25;
A TBK1-independent primordial function of STING in lysosomal biogenesis.
Lv B, Dion WA, Yang H, Xun J, Kim DH, Zhu B, Tan JX
Molecular cell 2024 Oct 17;84(20):3979-3996.e9
Molecular cell 2024 Oct 17;84(20):3979-3996.e9
NSUN2 regulates Wnt signaling pathway depending on the m5C RNA modification to promote the progression of hepatocellular carcinoma.
Xing H, Gu X, Liu Y, Xu L, He Y, Xue C
Oncogene 2024 Nov;43(47):3469-3482
Oncogene 2024 Nov;43(47):3469-3482
Oncogenic accumulation of cysteine promotes cancer cell proliferation by regulating the translation of D-type cyclins.
Okano Y, Yamauchi T, Fukuzaki R, Tsuruta A, Yoshida Y, Tsurudome Y, Ushijima K, Matsunaga N, Koyanagi S, Ohdo S
The Journal of biological chemistry 2024 Nov;300(11):107890
The Journal of biological chemistry 2024 Nov;300(11):107890
PELO regulates erythroid differentiation through interaction with MYC to upregulate KLF10.
Hao J, Han G, Liang X, Ruan Y, Huang C, Sa N, Hu H, Hu B, Li Z, Zhang K, Gao P, Dong X
The FEBS journal 2024 Nov;291(21):4714-4731
The FEBS journal 2024 Nov;291(21):4714-4731
The miR-665/SOST Axis Regulates the Phenotypes of Bone Marrow Mesenchymal Stem Cells and Osteoporotic Symptoms in Female Mice.
Zeng X, Yuan X, Liao H, Wei Y, Wu Q, Zhu X, Li Q, Chen S, Hu M
The American journal of pathology 2024 Nov;194(11):2059-2075
The American journal of pathology 2024 Nov;194(11):2059-2075
Epigenetic regulation of noncanonical menin targets modulates menin inhibitor response in acute myeloid leukemia.
Zhou X, Zhang L, Aryal S, Veasey V, Tajik A, Restelli C, Moreira S, Zhang P, Zhang Y, Hope KJ, Zhou Y, Cheng C, Bhatia R, Lu R
Blood 2024 Nov 7;144(19):2018-2032
Blood 2024 Nov 7;144(19):2018-2032
Oncogenic RTKs sensitize cancer cells to ferroptosis via c-Myc mediated upregulation of ACSL4.
Sun N, Wang J, Qin J, Ma S, Luan J, Hou G, Zhang W, Gao M
Cell death & disease 2024 Nov 27;15(11):861
Cell death & disease 2024 Nov 27;15(11):861
Chemo-Enzymatic Functionalization of Bovine Milk Exosomes with an EGFR Nanobody for Target-specific Drug Delivery.
Zhang R, Li D, Zhou Z, Hong H, Shi J, Wu Z
Chembiochem : a European journal of chemical biology 2024 Nov 18;25(22):e202400512
Chembiochem : a European journal of chemical biology 2024 Nov 18;25(22):e202400512
Protein profile of mouse endolymph suggests a role in controlling cochlear homeostasis.
Fukuda M, Okanishi H, Ino D, Ono K, Ota T, Wakai E, Sato T, Ohta Y, Kikkawa Y, Inohara H, Kanai Y, Hibino H
iScience 2024 Nov 15;27(11):111214
iScience 2024 Nov 15;27(11):111214
Inhibition of NPC1 suppresses cell proliferation and β-catenin signaling activation of liver cancer.
Cao D, Chen H, He M, Han N, Tang H
Journal of cancer research and clinical oncology 2024 Nov 15;150(11):498
Journal of cancer research and clinical oncology 2024 Nov 15;150(11):498
Multiomics profiling uncovers curdione-induced reproductive toxicity in HTR-8/SVneo cells.
Wu Q, Chen M, Lin Y, Zhang J, Gao X, Wu Y, Wu C, Wen J, Li J, Li C, Bao W, Zhang D, Zheng M, Zhu A
Heliyon 2024 Nov 15;10(21):e38650
Heliyon 2024 Nov 15;10(21):e38650
Immune Checkpoint-Modulating Photosensitizer That Targets BRD4 for Cancer Photoimmunotherapy.
Li P, Du Y, Qiu J, Jiang Q, Chen W, Zhang X, Li G, Li D, Shan G
Journal of medicinal chemistry 2024 Nov 14;67(21):18930-18942
Journal of medicinal chemistry 2024 Nov 14;67(21):18930-18942
N-Acetylneuraminic acid triggers endothelial pyroptosis and promotes atherosclerosis progression via GLS2-mediated glutaminolysis pathway.
Liu Z, Xiang P, Zeng S, Weng P, Wen Y, Zhang W, Hu H, Zhao D, Ma L, Yu C
Cell death discovery 2024 Nov 13;10(1):467
Cell death discovery 2024 Nov 13;10(1):467
Prognostic and immunotherapeutic implications of bilirubin metabolism-associated genes in lung adenocarcinoma.
Ren K, Ling X, Chen L, Li Z, Huang T
Journal of cellular and molecular medicine 2024 May;28(9):e18346
Journal of cellular and molecular medicine 2024 May;28(9):e18346
Alkenyl oxindole is a novel PROTAC moiety that recruits the CRL4DCAF11 E3 ubiquitin ligase complex for targeted protein degradation.
Wang Y, Wei T, Zhao M, Huang A, Sun F, Chen L, Lin R, Xie Y, Zhang M, Xu S, Sun Z, Hong L, Wang R, Tian R, Li G
PLoS biology 2024 May;22(5):e3002550
PLoS biology 2024 May;22(5):e3002550
A novel combined therapeutic strategy of Nano-EN-IR@Lip mediated photothermal therapy and stem cell inhibition for gastric cancer.
Yang L, Du YE, Liao F, Huang T, Liu Y, Liu J, Wang C, Zhan Z, Cao Y, Wang Z, Chen W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116486
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116486
Pervasive structural heterogeneity rewires glioblastoma chromosomes to sustain patient-specific transcriptional programs.
Xie T, Danieli-Mackay A, Buccarelli M, Barbieri M, Papadionysiou I, D'Alessandris QG, Robens C, Übelmesser N, Vinchure OS, Lauretti L, Fotia G, Schwarz RF, Wang X, Ricci-Vitiani L, Gopalakrishnan J, Pallini R, Papantonis A
Nature communications 2024 May 9;15(1):3905
Nature communications 2024 May 9;15(1):3905
ZDHHC20-mediated S-palmitoylation of YTHDF3 stabilizes MYC mRNA to promote pancreatic cancer progression.
Zhang H, Sun Y, Wang Z, Huang X, Tang L, Jiang K, Jin X
Nature communications 2024 May 31;15(1):4642
Nature communications 2024 May 31;15(1):4642
Transcriptional Up-Regulation of FBXW7 by K(Ca)1.1 K(+) Channel Inhibition through the Nrf2 Signaling Pathway in Human Prostate Cancer LNCaP Cell Spheroid Model.
Ohya S, Kito H, Kajikuri J, Yamaguchi Y, Matsui M
International journal of molecular sciences 2024 May 30;25(11)
International journal of molecular sciences 2024 May 30;25(11)
CXCL4:NLRP3-mediated pyroptosis product that regulates cardiac fibrosis.
Wei J, Peng MY, Wang SN, Lu HX
International immunopharmacology 2024 May 30;133:112096
International immunopharmacology 2024 May 30;133:112096
ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis.
He J, Yi J, Ji L, Dai L, Chen Y, Xue W
Molecular medicine (Cambridge, Mass.) 2024 May 23;30(1):69
Molecular medicine (Cambridge, Mass.) 2024 May 23;30(1):69
Targeted degradation of oncogenic BCR-ABL by silencing the gene of NEDD8 E3 ligase RAPSYN.
Sun Y, Wang Y, Liu C, Huang Y, Long Q, Ju C, Zhang C, Chen Y
Journal of nanobiotechnology 2024 May 13;22(1):247
Journal of nanobiotechnology 2024 May 13;22(1):247
HSPB8 binding to c-Myc alleviates hypoxia/reoxygenation-induced trophoblast cell dysfunction.
Chen L, Wu M, Zhou Y
Experimental and therapeutic medicine 2024 Mar;27(3):114
Experimental and therapeutic medicine 2024 Mar;27(3):114
Targeting carnitine palmitoyl transferase 1A (CPT1A) induces ferroptosis and synergizes with immunotherapy in lung cancer.
Ma L, Chen C, Zhao C, Li T, Ma L, Jiang J, Duan Z, Si Q, Chuang TH, Xiang R, Luo Y
Signal transduction and targeted therapy 2024 Mar 7;9(1):64
Signal transduction and targeted therapy 2024 Mar 7;9(1):64
TREM2 deficiency impairs the energy metabolism of Schwann cells and exacerbates peripheral neurological deficits.
Zhang N, Ji Q, Chen Y, Wen X, Shan F
Cell death & disease 2024 Mar 7;15(3):193
Cell death & disease 2024 Mar 7;15(3):193
EIF2Ss, a Novel c-Myc-Correlated Gene Family, is Associated with Poor Prognosis and Immune Infiltration in Pancreatic Adenocarcinoma.
Cao Z, Jing Y, Cheng C, Wang F, Guan M, Zhang K, Jiao J, Ruan L, Chen Z
Frontiers in bioscience (Landmark edition) 2024 Mar 21;29(3):119
Frontiers in bioscience (Landmark edition) 2024 Mar 21;29(3):119
Pan-cancer analysis of DDIT4 identifying its prognostic value and function in acute myeloid leukemia.
Li F, Miao J, Liu R, Zhang R, He A
Journal of cancer research and clinical oncology 2024 Mar 20;150(3):144
Journal of cancer research and clinical oncology 2024 Mar 20;150(3):144
5-AZA Upregulates SOCS3 and PTPN6/SHP1, Inhibiting STAT3 and Potentiating the Effects of AG490 against Primary Effusion Lymphoma Cells.
Di Crosta M, Arena A, Benedetti R, Gilardini Montani MS, Cirone M
Current issues in molecular biology 2024 Mar 14;46(3):2468-2479
Current issues in molecular biology 2024 Mar 14;46(3):2468-2479
An integrated investigation of sulfotransferases (SULTs) in hepatocellular carcinoma and identification of the role of SULT2A1 on stemness.
Peng H, Feng K, Jia W, Li Y, Lv Q, Zhang Y
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):898-919
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):898-919
YTHDF1 regulates immune cell infiltration in gastric cancer via interaction with p53.
Liao Q, Xiong J
Experimental and therapeutic medicine 2024 Jun;27(6):255
Experimental and therapeutic medicine 2024 Jun;27(6):255
METTL3 orchestrates glycolysis by stabilizing the c-Myc/WDR5 complex in triple-negative breast cancer.
Yuan XN, Shao YC, Guan XQ, Liu Q, Chu MF, Yang ZL, Li H, Zhao S, Tian YH, Zhang JW, Wei L
Biochimica et biophysica acta. Molecular cell research 2024 Jun;1871(5):119716
Biochimica et biophysica acta. Molecular cell research 2024 Jun;1871(5):119716
HnRNPA2B1 ISGylation Regulates m6A-Tagged mRNA Selective Export via ALYREF/NXF1 Complex to Foster Breast Cancer Development.
Jin T, Yang L, Chang C, Luo H, Wang R, Gan Y, Sun Y, Guo Y, Tang R, Chen S, Meng D, Dai P, Liu M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2307639
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2307639
OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway.
Wei H, Li W, Zeng L, Ding N, Li K, Yu H, Jiang F, Yin H, Xia Y, Deng C, Cai N, Chen X, Gu L, Chen H, Zhang F, He Y, Li J, Zhang C
Molecular cancer 2024 Jun 7;23(1):124
Molecular cancer 2024 Jun 7;23(1):124
SAHA/5-AZA Enhances Acetylation and Degradation of mutp53, Upregulates p21 and Downregulates c-Myc and BRCA-1 in Pancreatic Cancer Cells.
Di Crosta M, Ragone FC, Benedetti R, D'Orazi G, Gilardini Montani MS, Cirone M
International journal of molecular sciences 2024 Jun 27;25(13)
International journal of molecular sciences 2024 Jun 27;25(13)
TRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation.
Li T, Zhong W, Li M, Shao Z, Zhang G, Wang W, Gao Z, Tan X, Xu Z, Luo F, Song G
Cell death & disease 2024 Jun 26;15(6):453
Cell death & disease 2024 Jun 26;15(6):453
MEX3A promotes colorectal cancer migration, invasion and EMT via regulating the Wnt/β-catenin signaling pathway.
Xu J, Chen S, Hao T, Liu G, Zhang K, Zhang C, He Y
Journal of cancer research and clinical oncology 2024 Jun 25;150(6):319
Journal of cancer research and clinical oncology 2024 Jun 25;150(6):319
Identified γ-glutamyl cyclotransferase (GGCT) as a novel regulator in the progression and immunotherapy of pancreatic ductal adenocarcinoma through multi-omics analysis and experiments.
Zheng Y, Xiong Q, Yang Y, Ma Y, Zhu Q
Journal of cancer research and clinical oncology 2024 Jun 25;150(6):318
Journal of cancer research and clinical oncology 2024 Jun 25;150(6):318
C-MYC-activated lncRNA SNHG20 accelerates the proliferation of diffuse large B cell lymphoma via USP14-mediated deubiquitination of β-catenin.
Wang C, Fu W, Zhang Y, Hu X, Xu Q, Tong X
Biology direct 2024 Jun 18;19(1):47
Biology direct 2024 Jun 18;19(1):47
The Selective SIRT3 Inhibitor 3-TYP Represses Primary Myeloma Growth by Reducing c-Myc Stability.
Zeng Y, Zhang Y, Cui Z, Mao J, Xu J, Yao R
Chemical research in toxicology 2024 Jun 17;37(6):1062-1069
Chemical research in toxicology 2024 Jun 17;37(6):1062-1069
MYG1 drives glycolysis and colorectal cancer development through nuclear-mitochondrial collaboration.
Chen J, Duan S, Wang Y, Ling Y, Hou X, Zhang S, Liu X, Long X, Lan J, Zhou M, Xu H, Zheng H, Zhou J
Nature communications 2024 Jun 11;15(1):4969
Nature communications 2024 Jun 11;15(1):4969
Overexpression of FHL1 suppresses papillary thyroid cancer proliferation and progression via inhibiting Wnt/β-catenin pathway.
Chen J, Zeng C, Jin J, Zhang P, Zhang Y, Zhang H, Li Y, Guan H
Endocrine 2024 Jul;85(1):238-249
Endocrine 2024 Jul;85(1):238-249
Brd4::Nutm1 fusion gene initiates NUT carcinoma in vivo.
Zheng D, Elnegiry AA, Luo C, Bendahou MA, Xie L, Bell D, Takahashi Y, Hanna E, Mias GI, Tsoi MF, Gu B
Life science alliance 2024 Jul;7(7)
Life science alliance 2024 Jul;7(7)
NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance.
Chen H, Li Y, Li H, Chen X, Fu H, Mao D, Chen W, Lan L, Wang C, Hu K, Li J, Zhu C, Evans I, Cheung E, Lu D, He Y, Behrens A, Yin D, Zhang C
Nature 2024 Jul;631(8021):663-669
Nature 2024 Jul;631(8021):663-669
Major Facilitator Superfamily Domain Containing 12 Is Overexpressed in Lung Cancer and Exhibits an Oncogenic Role in Lung Adenocarcinoma Cells.
Zhao W, Hu X, Chen Z, Li X
DNA and cell biology 2024 Jul;43(7):331-340
DNA and cell biology 2024 Jul;43(7):331-340
Exploring the key genes associated with breast cancer radiotherapy sensitivity based on the stromal-immune score and analysis of the WGCNA and ceRNA network.
Sun X, Wu C, Lin Y, Zhang S, Zhao X, Wang X
Heliyon 2024 Jul 30;10(14):e34630
Heliyon 2024 Jul 30;10(14):e34630
Semaphorin 3C (Sema3C) reshapes stromal microenvironment to promote hepatocellular carcinoma progression.
Peng H, Yang M, Feng K, Lv Q, Zhang Y
Signal transduction and targeted therapy 2024 Jul 3;9(1):169
Signal transduction and targeted therapy 2024 Jul 3;9(1):169
Screening and identification of miRNAs negatively regulating FAM83A/Wnt/β-catenin signaling pathway in non-small cell lung cancer.
Yuan W, Liu W, Huang H, Chen X, Zhang R, Lyu H, Xiao S, Guo D, Zhang Q, Ali DW, Michalak M, Chen XZ, Zhou C, Tang J
Scientific reports 2024 Jul 29;14(1):17394
Scientific reports 2024 Jul 29;14(1):17394
Disintegration of Cav-1/β-catenin complex attenuates neuronal death after ischemia-reperfusion injury by promoting β-catenin nuclear translocation.
Guo P, Wang W, Liang Z, Li Y, Ou X, Li M, Wang B, Wei X, Huang L, Qi S
Molecular biology reports 2024 Jul 22;51(1):829
Molecular biology reports 2024 Jul 22;51(1):829
Repurposing AS1411 for constructing ANM-PROTACs.
Fu X, Li J, Chen X, Chen H, Wang Z, Qiu F, Xie D, Huang J, Yue S, Cao C, Liang Y, Lu A, Liang C
Cell chemical biology 2024 Jul 18;31(7):1290-1304.e7
Cell chemical biology 2024 Jul 18;31(7):1290-1304.e7
CD24 promotes metastasis and chemoresistance by directly targeting Arf6-ERK pathway in esophageal squamous cell carcinoma.
Hong P, Xu T, Xu J, Chen W, Hu H, Chen J, Li L, Zheng C, Li B, Liu J, Dai W, Li E, Zhang F, Xu W
Cancer letters 2024 Jul 10;594:216994
Cancer letters 2024 Jul 10;594:216994
3'-Hydroxypterostilbene Potently Suppresses Tumor Growth via Inhibiting the Activation of the JAK2/STAT3 Pathway in Ovarian Clear Cell Carcinoma.
Koh YC, Huang WZ, Nagabhushanam K, Ho CT, Pan MH
Molecular nutrition & food research 2024 Jan;68(1):e2300108
Molecular nutrition & food research 2024 Jan;68(1):e2300108
Circular RNA circXPO1 Promotes Multiple Myeloma Progression by Regulating miR-495-3p/DNA Damage-Induced Transcription 4 Axis.
Li F, Liu J, Miao J, Hong F, Liu R, Lv Y, Yang Y, He A, Wang J
DNA and cell biology 2024 Jan;43(1):39-55
DNA and cell biology 2024 Jan;43(1):39-55
Arginine-methylated c-Myc affects mitochondrial mitophagy in mouse acute kidney injury via Slc25a24.
Liu Y, Liu N, He P, Cao S, Li H, Liu D
Journal of cellular physiology 2024 Jan;239(1):193-211
Journal of cellular physiology 2024 Jan;239(1):193-211
MYSM1 acts as a novel co-activator of ERα to confer antiestrogen resistance in breast cancer.
Luan R, He M, Li H, Bai Y, Wang A, Sun G, Zhou B, Wang M, Wang C, Wang S, Zeng K, Feng J, Lin L, Wei Y, Kato S, Zhang Q, Zhao Y
EMBO molecular medicine 2024 Jan;16(1):10-39
EMBO molecular medicine 2024 Jan;16(1):10-39
Effects and mechanisms of frehmaglutin D and rehmaionoside C improve LPS-induced acute kidney injury through the estrogen receptor-mediated TLR4 pathway in vivo and in vitro.
Liu M, Guo P, Zeng M, Zhang Y, Jia J, Liu Y, Chen X, Kuang H, Feng W, Zheng X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155218
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155218
Taxifolin inhibits melanoma proliferation/migration impeding USP18/Rac1/JNK/β-catenin oncogenic signaling.
Xu L, Zhang L, Zhang S, Yang J, Zhu A, Sun J, Kalvakolanu DV, Cong X, Zhang J, Tang J, Guo B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155199
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155199
Deubiquitinase OTUB1 regulates doxorubicin-induced cardiotoxicity via deubiquitinating c-MYC.
Xu F, Zang T, Chen H, Zhou C, Wang R, Yu Y, Shen L, Qian J, Ge J
Cellular signalling 2024 Jan;113:110937
Cellular signalling 2024 Jan;113:110937
The feedback loop of EFTUD2/c-MYC impedes chemotherapeutic efficacy by enhancing EFTUD2 transcription and stabilizing c-MYC protein in colorectal cancer.
Zhu X, Li C, Gao Y, Zhang Q, Wang T, Zhou H, Bu F, Chen J, Mao X, He Y, Wu K, Li N, Luo H
Journal of experimental & clinical cancer research : CR 2024 Jan 2;43(1):7
Journal of experimental & clinical cancer research : CR 2024 Jan 2;43(1):7
Characterization and verification of CD81 as a potential target in lung squamous cell carcinoma.
Ye X, Deng J, Dong C, Pan X, Lu Y
Biochemical and biophysical research communications 2024 Jan 15;692:149344
Biochemical and biophysical research communications 2024 Jan 15;692:149344
TRIM56 protects against nonalcoholic fatty liver disease by promoting the degradation of fatty acid synthase.
Xu S, Wu X, Wang S, Xu M, Fang T, Ma X, Chen M, Fu J, Guo J, Tian S, Tian T, Cheng X, Yang H, Zhou J, Wang Z, Yin Y, Xu W, Xu F, Yan J, Wang Z, Luo S, Zhang XJ, Ji YX, Weng J
The Journal of clinical investigation 2024 Jan 11;134(5)
The Journal of clinical investigation 2024 Jan 11;134(5)
Npc1 gene mutation abnormally activates the classical Wnt signalling pathway in mouse kidneys and promotes renal fibrosis.
Guan L, Jia Z, Xu K, Yang M, Li X, Qiao L, Liu Y, Lin J
Animal genetics 2024 Feb;55(1):99-109
Animal genetics 2024 Feb;55(1):99-109
Efficacy of Yisui granule on myelodysplastic syndromes in SKM-1 mouse xenograft model through suppressing Wnt/β-catenin signaling pathway.
Jieya WU, Li H, Xiaoyuan Z, Gullen E, Chong G, Jing W
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Feb;44(1):78-87
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Feb;44(1):78-87
LATS1/YAP1 Axis Controls Bone Regeneration on Distraction Osteogenesis by Activating Wnt/β-Catenin.
Li K, Liu L, Liu H, Xing J, Hu P, Song J
Tissue engineering. Part A 2024 Feb;30(3-4):154-167
Tissue engineering. Part A 2024 Feb;30(3-4):154-167
Tumor suppressive function of IGF2BP1 in gastric cancer through decreasing MYC.
Ding N, Cao G, Wang Z, Xu S, Chen W
Cancer science 2024 Feb;115(2):427-438
Cancer science 2024 Feb;115(2):427-438
Protein phosphatase 1 regulatory subunit 15 A promotes translation initiation and induces G2M phase arrest during cuproptosis in cancers.
Liu C, Chen L, Cong Y, Cheng L, Shuai Y, Lv F, Chen K, Song Y, Xing Y
Cell death & disease 2024 Feb 16;15(2):149
Cell death & disease 2024 Feb 16;15(2):149
Curcumin triggers the Wnt/β-catenin pathway and shields neurons from injury caused by intermittent hypoxia.
He Y, Zhao Y, Lv RJ, Dong N, Wang X, Yu Q, Yue HM
Tissue & cell 2024 Dec;91:102587
Tissue & cell 2024 Dec;91:102587
Icariin ameliorates Coxsackievirus B3-induced viral myocarditis by modulating the S100 calcium binding protein A6/β-catenin/c-Myc signaling pathway.
Tian H, Pan Q, Wu J, Liao J, Wan Y, Pei K, Liu Q, Zeng L, Cao Y, Shi Q, Kuang N, Sun L, Yu X, Huang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156214
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156214
MiR-135b-5p promotes cetuximab resistance in colorectal cancer by regulating FOXN3.
Peng C, Li X, Yao Y, Nie Y, Fan L, Zhu C
Cancer biology & therapy 2024 Dec 31;25(1):2373497
Cancer biology & therapy 2024 Dec 31;25(1):2373497
RBIS regulates ribosome biogenesis to affect progression in lung adenocarcinoma.
Pan H, Liao L, Xu S, Xu Y, Chai W, Liu X, Li J, Cao Y, Sun L, Liu Q, Yan M
Journal of translational medicine 2024 Dec 25;22(1):1147
Journal of translational medicine 2024 Dec 25;22(1):1147
Curcumin activates the Wnt/β-catenin signaling pathway to alleviate hippocampal neurogenesis abnormalities caused by intermittent hypoxia: A study based on network pharmacology and experimental verification.
He Y, Zhao Y, Lv RJ, Dong N, Wang X, Yu Q, Yue HM
International immunopharmacology 2024 Dec 25;143(Pt 1):113299
International immunopharmacology 2024 Dec 25;143(Pt 1):113299
TFAP2C-mediated transcriptional activation of STEAP3 promotes lung squamous cell carcinoma progression by regulating the β-catenin pathway.
Sun T, Yang Z
Biology direct 2024 Dec 24;19(1):135
Biology direct 2024 Dec 24;19(1):135
Modeling gastric intestinal metaplasia in 3D organoids using nitrosoguanidine.
Li Y, Chen J, Li T, Lin J, Zheng H, Johnson N, Yao X, Ding X
Journal of molecular cell biology 2024 Dec 20;16(7)
Journal of molecular cell biology 2024 Dec 20;16(7)
The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release.
Wang Z, Song A, Tao B, Miao M, Luo YQ, Wang J, Yin Z, Xiao R, Zhou X, Shang XY, Hu S, Liang K, Danko CG, Chen FX
Molecular cell 2024 Dec 19;84(24):4824-4842.e7
Molecular cell 2024 Dec 19;84(24):4824-4842.e7
Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signaling.
Gong K, Zheng Y, Liu Y, Zhang T, Song Y, Chen W, Guo L, Zhou J, Liu W, Fang T, Chen Y, Wang J, Pan F, Shi K
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):3
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):3
Dysfunction of astrocytic glycophagy exacerbates reperfusion injury in ischemic stroke.
Guo H, Li Y, Wang S, Yang Y, Xu T, Zhao J, Wang J, Zuo W, Wang P, Zhao G, Wang H, Hou W, Dong H, Cai Y
Redox biology 2024 Aug;74:103234
Redox biology 2024 Aug;74:103234
Overcoming retinoic acid resistance in HER2-enriched breast cancers: role of MYC.
Choi WS, Liu RZ, Mak C, Maadi H, Godbout R
The FEBS journal 2024 Aug;291(15):3521-3538
The FEBS journal 2024 Aug;291(15):3521-3538
P4HA3 promotes head and neck squamous cell carcinoma progression via the WNT/β-catenin signaling pathway.
Wang Q, Meng D, Shen S, Cao Y, Zhang P, Liu Y, Du L, Li H, Shao C, Dong Q
Pathology, research and practice 2024 Aug;260:155481
Pathology, research and practice 2024 Aug;260:155481
Epigenetic repression of de novo cysteine synthetases induces intra-cellular accumulation of cysteine in hepatocarcinoma by up-regulating the cystine uptake transporter xCT.
Yamauchi T, Okano Y, Terada D, Yasukochi S, Tsuruta A, Tsurudome Y, Ushijima K, Matsunaga N, Koyanagi S, Ohdo S
Cancer & metabolism 2024 Aug 7;12(1):23
Cancer & metabolism 2024 Aug 7;12(1):23
Inhibition of KIF20A enhances the immunotherapeutic effect of hepatocellular carcinoma by enhancing c-Myc ubiquitination.
Chen S, Zhao L, Liu J, Han P, Jiang W, Liu Y, Hou J, Wang F, Li J
Cancer letters 2024 Aug 28;598:217105
Cancer letters 2024 Aug 28;598:217105
DNA damage response-related signatures characterize the immune landscape and predict the prognosis of HCC via integrating single-cell and bulk RNA-sequencing.
Li H, Shi Y, Li Y, Wu S, Yang R, Liu Q, Sun L
International immunopharmacology 2024 Aug 20;137:112475
International immunopharmacology 2024 Aug 20;137:112475
Progesterone (P4) ameliorates cigarette smoke-induced chronic obstructive pulmonary disease (COPD).
Xie B, Chen Q, Dai Z, Jiang C, Chen X
Molecular medicine (Cambridge, Mass.) 2024 Aug 13;30(1):123
Molecular medicine (Cambridge, Mass.) 2024 Aug 13;30(1):123
CUDC-907 exhibits potent antitumor effects against ovarian cancer through multiple in vivo and in vitro mechanisms.
Wang Y, Wen J, Sun X, Sun Y, Liu Y, Cheng X, Wu W, Liu Q, Ren F
Cancer chemotherapy and pharmacology 2024 Apr;93(4):295-306
Cancer chemotherapy and pharmacology 2024 Apr;93(4):295-306
RAE1 promotes gastric carcinogenesis and epithelial-mesenchymal transition.
Dong W, Li X, Cheng L, Yang J, Zhao Z, Qiang X, Li P, Wu J, Guo L
Archives of biochemistry and biophysics 2024 Apr;754:109896
Archives of biochemistry and biophysics 2024 Apr;754:109896
Pyrogallol promotes growth arrest by activating the p53-mediated up-regulation of p21 and p62/SQSTM1-dependent degradation of β-catenin in nonsmall cell lung cancer cells.
Zhou B, Wang L, Ren Z, Liang Y, Yang S, Zhang Y, Che S, Fang W
Environmental toxicology 2024 Apr;39(4):2150-2165
Environmental toxicology 2024 Apr;39(4):2150-2165
Integrative analysis unveils ECM signatures and pathways driving hepatocellular carcinoma progression: A multi-omics approach and prognostic model development.
Liu Z, Zhao P
Journal of cellular and molecular medicine 2024 Apr;28(8):e18230
Journal of cellular and molecular medicine 2024 Apr;28(8):e18230
Cellular nucleic acid binding protein facilitates cardiac repair after myocardial infarction by activating β-catenin signaling.
Du C, Zhao S, Shan T, Han X, Jiang Q, Chen J, Gu L, Wei T, Yang T, Wang S, Wang H, Guo X, Wang L
Journal of molecular and cellular cardiology 2024 Apr;189:66-82
Journal of molecular and cellular cardiology 2024 Apr;189:66-82
Inhibition of PTPRE suppresses tumor progression and improves sorafenib response in hepatocellular carcinoma.
Dong R, Wang T, Dong W, Zhu H, Liu Q, Liang H, Chen X, Zhang B, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116366
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116366
Hippo/YAP1 promotes osteoporotic mice bone defect repair via the activating of Wnt signaling pathway.
Li K, Liu L, Liu H, Liu Y, Xing J, Song J, Luo E
Cellular signalling 2024 Apr;116:111037
Cellular signalling 2024 Apr;116:111037
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Lai W, Yu L, Deng Y
Communications biology 2024 Apr 9;7(1):429
Communications biology 2024 Apr 9;7(1):429
Genetic interactions reveal distinct biological and therapeutic implications in breast cancer.
Lin CJ, Jin X, Ma D, Chen C, Ou-Yang Y, Pei YC, Zhou CZ, Qu FL, Wang YJ, Liu CL, Fan L, Hu X, Shao ZM, Jiang YZ
Cancer cell 2024 Apr 8;42(4):701-719.e12
Cancer cell 2024 Apr 8;42(4):701-719.e12
A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis.
Bao K, Ma Y, Li Y, Shen X, Zhao J, Tian S, Zhang C, Liang C, Zhao Z, Yang Y, Zhang K, Yang N, Meng FL, Hao J, Yang J, Liu T, Yao Z, Ai D, Shi L
Molecular cell 2024 Apr 4;84(7):1206-1223.e15
Molecular cell 2024 Apr 4;84(7):1206-1223.e15
ELP3 stabilizes c-Myc to promote tumorigenesis.
Zhao W, Ouyang C, Huang C, Zhang J, Xiao Q, Zhang F, Wang H, Lin F, Wang J, Wang Z, Jiang B, Li Q
Journal of molecular cell biology 2024 Apr 4;15(9)
Journal of molecular cell biology 2024 Apr 4;15(9)
Melatonin inhibits tongue squamous cell carcinoma: Interplay of ER stress-induced apoptosis and autophagy with cell migration.
Liu H, Zheng Y, Kan S, Hao M, Jiang H, Li S, Li R, Wang Y, Wang D, Liu W
Heliyon 2024 Apr 30;10(8):e29291
Heliyon 2024 Apr 30;10(8):e29291
Glutamine Promotes Porcine Intestinal Epithelial Cell Proliferation through the Wnt/β-Catenin Pathway.
Fang YX, Lu EQ, Cheng YJ, Xu E, Zhu M, Chen X
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7155-7166
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7155-7166
DCDC2 inhibits hepatic stellate cell activation and ameliorates CCl(4)-induced liver fibrosis by suppressing Wnt/β-catenin signaling.
Liu QQ, Chen J, Ma T, Huang W, Lu CH
Scientific reports 2024 Apr 24;14(1):9425
Scientific reports 2024 Apr 24;14(1):9425
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression.
Wu J, Wen T, Marzio A, Song D, Chen S, Yang C, Zhao F, Zhang B, Zhao G, Ferri A, Cheng H, Ma J, Ren H, Chen QY, Yang Y, Qin S
Cell death & disease 2024 Apr 20;15(4):282
Cell death & disease 2024 Apr 20;15(4):282
A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice.
Ma X, Yin J, Qiao L, Wan H, Liu X, Zhou Y, Wu J, Niu L, Wu M, Wang X, Ye H
Molecular cell 2024 Apr 18;84(8):1585-1600.e7
Molecular cell 2024 Apr 18;84(8):1585-1600.e7
Single-cell and Spatial Transcriptomics Identified Fatty Acid-binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension.
Liu B, Yi D, Li S, Ramirez K, Xia X, Cao Y, Zhao H, Tripathi A, Qiu S, Kala M, Rafikov R, Gu H, de Jesus Perez V, Lemay SE, Glembotski CC, Knox KS, Bonnet S, Kalinichenko VV, Zhao YY, Fallon MB, Boucherat O, Dai Z
bioRxiv : the preprint server for biology 2024 Apr 15;
bioRxiv : the preprint server for biology 2024 Apr 15;
Novel BRD4-p53 Inhibitor SDU-071 Suppresses Proliferation and Migration of MDA-MB-231 Triple-Negative Breast Cancer Cells.
Wang S, Lei K, Lai HT, Liu T, Du L, Wu SY, Ye X, Chiang CM, Li M
ACS pharmacology & translational science 2024 Apr 12;7(4):1178-1190
ACS pharmacology & translational science 2024 Apr 12;7(4):1178-1190
Hawthorn Proanthocyanidin Extract Inhibits Colorectal Carcinoma Metastasis by Targeting the Epithelial-Mesenchymal Transition Process and Wnt/β-Catenin Signaling Pathway.
Wang Z, Sun Y, Wu M, Zhou L, Zheng Y, Ren T, Li M, Zhao W
Foods (Basel, Switzerland) 2024 Apr 12;13(8)
Foods (Basel, Switzerland) 2024 Apr 12;13(8)
Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma.
Zhou Y, Ray PS, Zhu J, Stein F, Rettel M, Sekaran T, Sahadevan S, Perez-Perri JI, Roth EK, Myklebost O, Meza-Zepeda LA, von Deimling A, Fu C, Brosig AN, Boye K, Nathrath M, Blattmann C, Lehner B, Hentze MW, Kulozik AE
Nature communications 2024 Apr 1;15(1):2810
Nature communications 2024 Apr 1;15(1):2810
ASPM overexpression enhances cellular proliferation and migration and predicts worse prognosis for papillary renal cell carcinoma.
Li N, Chu J, Hu K, Zhang H, Li N, Chu JF, Hu KY, Zhang HY
Journal of biosciences 2023;48
Journal of biosciences 2023;48
GPC3 Promotes Lung Squamous Cell Carcinoma Progression and HLA-A2-Restricted GPC3 Antigenic Peptide-Modified Dendritic Cell-Induced Cytotoxic T Lymphocytes to Kill Lung Squamous Cell Carcinoma Cells.
Ning J, Ding J, Wang S, Jiang Y, Wang D, Jiang S
Journal of immunology research 2023;2023:5532617
Journal of immunology research 2023;2023:5532617
Parkin increases the risk of colitis by downregulation of VDR via autophagy-lysosome degradation.
Ma Z, Wu J, Wu Y, Sun X, Rao Z, Sun N, Fu Y, Zhang Z, Li J, Xiao M, Zeng Q, Wu Y, Han C, Ding D, Zhang H, Yuan H, Zhang J, Yang S, Chen Y
International journal of biological sciences 2023;19(5):1633-1644
International journal of biological sciences 2023;19(5):1633-1644
FAK downregulation suppresses stem-like properties and migration of human colorectal cancer cells.
Xu C, Zhang W, Liu C
PloS one 2023;18(4):e0284871
PloS one 2023;18(4):e0284871
UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway.
Wang Y, Gao G, Wei X, Zhang Y, Yu J
Drug design, development and therapy 2023;17:1357-1369
Drug design, development and therapy 2023;17:1357-1369
Esomeprazole Alleviates Cisplatin Resistance by Inhibiting the AKT/mTOR Pathway in Ovarian Cancer Cells.
Duan J, Zhang Z, Du J, Zhang J, Li M, Li C
OncoTargets and therapy 2023;16:425-440
OncoTargets and therapy 2023;16:425-440
Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells.
Wang M, Zhang Y, Liu M, Jia Y, He J, Xu X, Shi H, Zhang Y, Zhang J, Liu Y
Journal of Cancer 2023;14(4):611-627
Journal of Cancer 2023;14(4):611-627
Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study.
Li Y, Yang X, Wang F, Zhao J, Zhang C, Wu D, Yang B, Gao R, Zhao P, Zan Y, Su M, He Z, Liu Y, Wang J, Tang D
Frontiers in pharmacology 2023;14:1076815
Frontiers in pharmacology 2023;14:1076815
UBE2S targets RPL26 for ubiquitination and degradation to promote non-small cell lung cancer progression via regulating c-Myc.
Gong D, Rao X, Min Z, Liu X, Xin H, Zhou P, Yang L, Li D
American journal of cancer research 2023;13(8):3705-3720
American journal of cancer research 2023;13(8):3705-3720
Onvansertib inhibits the proliferation and improves the cisplatin-resistance of lung adenocarcinoma via β-catenin/c-Myc signaling pathway.
Wang R, Hou Y, Geng G, Zhu X, Wang Z, Cai W, Ye J, Zhao S, Mi Y, Jiang J
American journal of cancer research 2023;13(2):623-637
American journal of cancer research 2023;13(2):623-637
E3 ubiquitin ligase TRIM21 targets TIF1γ to regulate β-catenin signaling in glioblastoma.
Li Y, Bao L, Zheng H, Geng M, Chen T, Dai X, Xiao H, Yang L, Mao C, Qiu Y, Xu Y, Wang D, Li MX, Chen Q
Theranostics 2023;13(14):4919-4935
Theranostics 2023;13(14):4919-4935
RNA N6-methyladenosine reader IGF2BP3 promotes acute myeloid leukemia progression by controlling stabilization of EPOR mRNA.
Fan J, Zhuang M, Fan W, Hou M
PeerJ 2023;11:e15706
PeerJ 2023;11:e15706
Increased α-HB links colorectal cancer and diabetes by potentiating NF-κB signaling.
Lv X, Ding P, Li L, Li L, Zhou D, Wang X, Chen J, Zhang W, Wang Q, Liao T, Wen W, Zhou D, Ji QH, He X, Lei QY, Hu W
Molecular metabolism 2023 Sep;75:101766
Molecular metabolism 2023 Sep;75:101766
Identification of a diketopiperazine-based O-GlcNAc transferase inhibitor sensitizing hepatocellular carcinoma to CDK9 inhibition.
Shan X, Jiang R, Gou D, Xiang J, Zhou P, Xia J, Wang K, Huang A, Tang N, Huang L
The FEBS journal 2023 Sep;290(18):4543-4561
The FEBS journal 2023 Sep;290(18):4543-4561
Loss of NSUN6 inhibits osteosarcoma progression by downregulating EEF1A2 expression and activation of Akt/mTOR signaling pathway via m(5)C methylation.
Hu S, Yang M, Xiao K, Yang Z, Cai L, Xie Y, Wang L, Wei R
Experimental and therapeutic medicine 2023 Sep;26(3):457
Experimental and therapeutic medicine 2023 Sep;26(3):457
SNTB1 regulates colorectal cancer cell proliferation and metastasis through YAP1 and the WNT/β-catenin pathway.
Zhang H, Li Z, Jiang J, Lei Y, Xie J, Liu Y, Yi B
Cell cycle (Georgetown, Tex.) 2023 Sep;22(17):1865-1883
Cell cycle (Georgetown, Tex.) 2023 Sep;22(17):1865-1883
Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling.
Erzurumlu Y, Dogan HK, Catakli D, Aydogdu E, Muhammed MT
Journal of cell communication and signaling 2023 Sep;17(3):793-811
Journal of cell communication and signaling 2023 Sep;17(3):793-811
Nucleolar HEAT Repeat Containing 1 Up-regulated by the Mechanistic Target of Rapamycin Complex 1 Signaling Promotes Hepatocellular Carcinoma Growth by Dominating Ribosome Biogenesis and Proteome Homeostasis.
Yang XM, Wang XQ, Hu LP, Feng MX, Zhou YQ, Li DX, Li J, Miao XC, Zhang YL, Yao LL, Nie HZ, Huang S, Xia Q, Zhang XL, Jiang SH, Zhang ZG
Gastroenterology 2023 Sep;165(3):629-646
Gastroenterology 2023 Sep;165(3):629-646
Ginsenoside Rh4 delays skeletal muscle aging through SIRT1 pathway.
Zhu A, Duan Z, Chen Y, Zhu C, Fan D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154906
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154906
CCDC85C suppresses colorectal cancer cells proliferation and metastasis through activating GSK-3β and promoting β-catenin degradation.
Hu W, Shen J, Tao Y, Dong D, Lu S, Li L, Sun D, Fan M, Xu C, Shen W, Yu C, Cheng H
Cellular signalling 2023 Sep;109:110799
Cellular signalling 2023 Sep;109:110799
Triiodothyronine positively regulates endoplasmic reticulum-associated degradation (ERAD) and promotes androgenic signaling in androgen-dependent prostate cancer cells.
Erzurumlu Y, Muhammed MT
Cellular signalling 2023 Sep;109:110745
Cellular signalling 2023 Sep;109:110745
Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC.
Zhao X, Guo B, Sun W, Yu J, Cui L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2206878
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2206878
Oridonin inhibits the occurrence and development of colorectal cancer by reversing the Warburg effect via reducing PKM2 dimer formation and preventing its entry into the nucleus.
Chen F, Liao J, Wu P, Cheng L, Ma Y, Zhang L, Leng X, Zhu X, Liu Z, Xie F
European journal of pharmacology 2023 Sep 5;954:175856
European journal of pharmacology 2023 Sep 5;954:175856
ALDOC promotes non-small cell lung cancer through affecting MYC-mediated UBE2N transcription and regulating Wnt/β-catenin pathway.
Shang B, Lu F, Jiang S, Xing M, Mao X, Yang G, Zhang H
Aging 2023 Sep 18;15(18):9614-9632
Aging 2023 Sep 18;15(18):9614-9632
ESRRB Inhibits the TGFβ Signaling Pathway to Drive Cell Proliferation in Cervical Cancer.
Li QS, Zheng PS
Cancer research 2023 Sep 15;83(18):3095-3114
Cancer research 2023 Sep 15;83(18):3095-3114
MDIG-mediated H3K9me3 demethylation upregulates Myc by activating OTX2 and facilitates liver regeneration.
Du J, Liao W, Wang H, Hou G, Liao M, Xu L, Huang J, Yuan K, Chen X, Zeng Y
Signal transduction and targeted therapy 2023 Sep 15;8(1):351
Signal transduction and targeted therapy 2023 Sep 15;8(1):351
Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1.
Guo Z, Guo L
Experimental cell research 2023 Sep 15;430(2):113714
Experimental cell research 2023 Sep 15;430(2):113714
DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway.
Wen R, Zhou L, Jiang S, Fan H, Zheng K, Yu Y, Gao X, Hao L, Lou Z, Yu G, Yang F, Zhang W
International journal of radiation oncology, biology, physics 2023 Sep 1;117(1):198-210
International journal of radiation oncology, biology, physics 2023 Sep 1;117(1):198-210
Knockdown of LINC00702 inhibits the growth and induces apoptosis of breast cancer through the Wnt/β-catenin pathway.
Chai D, Yang C, Liu Y, Li H, Lian B, Bai Z, Li J
Heliyon 2023 Oct;9(10):e20651
Heliyon 2023 Oct;9(10):e20651
Abnormal expression of CEBPB promotes the progression of renal cell carcinoma through regulating the generation of IL-6.
Ren Y, Guo W, Qiao B
Heliyon 2023 Oct;9(10):e20175
Heliyon 2023 Oct;9(10):e20175
ANKRD22 knockdown suppresses papillary thyroid cell carcinoma growth and migration and modulates the Wnt/β-catenin signaling pathway.
Wu Y, Chen W, Zhang B, Liu H
Tissue & cell 2023 Oct;84:102193
Tissue & cell 2023 Oct;84:102193
Discovery of an Heparin-Binding Epidermal Growth Factor Domain Antibody from a Phage Library and Analysis of Its Inhibitory Effects in SKOV3 Cells.
Lü P, Qiu S, Pan Y, Shi S, Yu Q, Yu F, Miao L, Wang H, Chen K
Cancer biotherapy & radiopharmaceuticals 2023 Oct;38(8):572-579
Cancer biotherapy & radiopharmaceuticals 2023 Oct;38(8):572-579
HBV precore G1896A mutation promotes growth of hepatocellular carcinoma cells by activating ERK/MAPK pathway.
Zhao B, Qiao H, Zhao Y, Gao Z, Wang W, Cui Y, Li J, Guo Z, Chuai X, Chiu S
Virologica Sinica 2023 Oct;38(5):680-689
Virologica Sinica 2023 Oct;38(5):680-689
IGF2BP2 promotes ovarian cancer growth and metastasis by upregulating CKAP2L protein expression in an m(6) A-dependent manner.
Shi Y, Xiong X, Sun Y, Geng Z, Chen X, Cui X, Lv J, Ge L, Jia X, Xu J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23183
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23183
Upregulation of SOX9 promotes the self-renewal and tumorigenicity of cervical cancer through activating the Wnt/β-catenin signaling pathway.
Feng Q, Cui N, Li S, Cao J, Chen Q, Wang H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23174
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23174
LncRNA BCAN-AS1 stabilizes c-Myc via N(6)-methyladenosine-mediated binding with SNIP1 to promote pancreatic cancer.
Wu G, Su J, Zeng L, Deng S, Huang X, Ye Y, Li R, Bai R, Zhuang L, Li M, Zhou Q, Zheng Y, Deng J, Zhang S, Chen R, Lin D, Zhang J, Zheng J
Cell death and differentiation 2023 Oct;30(10):2213-2230
Cell death and differentiation 2023 Oct;30(10):2213-2230
RRM2‑mediated Wnt/β‑catenin signaling pathway activation in lung adenocarcinoma: A potential prognostic biomarker.
Jiang Y, Hu X, Pang M, Huang Y, Ren B, He L, Jiang L
Oncology letters 2023 Oct;26(4):417
Oncology letters 2023 Oct;26(4):417
Proliferation-associated 2G4 P48 is stabilized by malignant T-cell amplified sequence 1 and promotes the proliferation of head and neck squamous cell carcinoma.
Sun L, Xing G, Wang W, Ma X, Bu X
Journal of dental sciences 2023 Oct;18(4):1588-1597
Journal of dental sciences 2023 Oct;18(4):1588-1597
Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer.
Sun X, Ye G, Li J, Shou H, Bai G, Zhang J
Clinical and translational medicine 2023 Oct;13(10):e1457
Clinical and translational medicine 2023 Oct;13(10):e1457
Elucidating the pharmacological effects of Compound Kushen injection on MYC-P15-CCND1 signaling pathway in nasopharyngeal carcinoma - An in vitro study.
Wu Z, Wu C, Shi J, Huang Z, Lu S, Tan Y, You R, Hai L, Huang J, Guo S, Gao Y, Jin Z, Tao X, You L, Wu J
Journal of ethnopharmacology 2023 Oct 28;315:116702
Journal of ethnopharmacology 2023 Oct 28;315:116702
HHV-6A Infection of Papillary Thyroid Cancer Cells Induces Several Effects Related to Cancer Progression.
Mardente S, Romeo MA, Asquino A, Po A, Gilardini Montani MS, Cirone M
Viruses 2023 Oct 19;15(10)
Viruses 2023 Oct 19;15(10)
Novel c-Myc G4 stabilizer EP12 promotes myeloma cytotoxicity by disturbing NF-κB signaling.
Yao R, Zhang Y, Zeng Y, Zhang Y, Liu L, Gao J
Experimental cell research 2023 Oct 1;431(1):113759
Experimental cell research 2023 Oct 1;431(1):113759
Baicalein Attenuates Neuroinflammation in LPS-Treated BV-2 Cells by Inhibiting Glycolysis via STAT3/c-Myc Pathway.
Gao L, Liu YX, Zhou YZ, Qin XM
Neurochemical research 2023 Nov;48(11):3363-3377
Neurochemical research 2023 Nov;48(11):3363-3377
O-GlcNAc has crosstalk with ADP-ribosylation via PARG.
Li J, Liu X, Peng B, Feng T, Zhou W, Meng L, Zhao S, Zheng X, Wu C, Wu S, Chen X, Xu X, Sun J, Li J
The Journal of biological chemistry 2023 Nov;299(11):105354
The Journal of biological chemistry 2023 Nov;299(11):105354
Hsa_circ_0001479 accelerates tumorigenesis of gastric cancer and mediates immune escape.
Zang J, Xiao L, Shi X, Liu S, Wang Y, Sun B, Ju S, Cui M, Jing R
International immunopharmacology 2023 Nov;124(Pt A):110887
International immunopharmacology 2023 Nov;124(Pt A):110887
HSP110 Inhibition in Primary Effusion Lymphoma Cells: One Molecule, Many Pro-Survival Targets.
Gonnella R, Zarrella R, Di Crosta M, Benedetti R, Arena A, Santarelli R, Gilardini Montani MS, D'Orazi G, Cirone M
Cancers 2023 Nov 29;15(23)
Cancers 2023 Nov 29;15(23)
m6A modified BACE1-AS contributes to liver metastasis and stemness-like properties in colorectal cancer through TUFT1 dependent activation of Wnt signaling.
Wang X, Liu Y, Zhou M, Yu L, Si Z
Journal of experimental & clinical cancer research : CR 2023 Nov 21;42(1):306
Journal of experimental & clinical cancer research : CR 2023 Nov 21;42(1):306
The role of an amphiphilic helix and transmembrane region in the efficient acylation of the M2 protein from influenza virus.
Meng X, Templeton C, Clementi C, Veit M
Scientific reports 2023 Nov 2;13(1):18928
Scientific reports 2023 Nov 2;13(1):18928
SHFM1 deficiency suppresses esophageal squamous cell carcinomas progression via modulating NF‑κB signaling and enhancing nature killer cell‑mediated tumor surveillance.
Wu Y, Wang Z, Li S, Chen X, Zhou S
Experimental and therapeutic medicine 2023 May;25(5):195
Experimental and therapeutic medicine 2023 May;25(5):195
DNMT3A R882H mutation promotes acute leukemic cell survival by regulating glycolysis through the NRF2/NQO1 axis.
Chu X, Zhong L, Dan W, Wang X, Zhang Z, Liu Z, Lu Y, Shao X, Zhou Z, Chen S, Liu B
Cellular signalling 2023 May;105:110626
Cellular signalling 2023 May;105:110626
NCBP1 enhanced proliferation of DLBCL cells via METTL3-mediated m6A modification of c-Myc.
Meng S, Xia Y, Li M, Wu Y, Wang D, Zhou Y, Ma D, Ye J, Sun T, Ji C
Scientific reports 2023 May 27;13(1):8606
Scientific reports 2023 May 27;13(1):8606
Guanine nucleotide exchange factor T exerts the cancer-promoting function in cholangiocarcinoma by enhancing the Wnt-GSK-3β-β-catenin cascade via regulation of Rac1/Cdc42.
Wang X, Zhang X, Sun J, Sun Y, Zhang Y, He L, Wang P, Li F, Sun C
Toxicology and applied pharmacology 2023 May 15;467:116492
Toxicology and applied pharmacology 2023 May 15;467:116492
PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression.
Li Z, Chen C, Yong H, Jiang L, Wang P, Meng S, Chu S, Li Z, Guo Q, Zheng J, Bai J, Li H
Cell death & disease 2023 May 12;14(5):322
Cell death & disease 2023 May 12;14(5):322
Decreasing expression of Prohibitin-2 lowers the oncogenicity of renal cell carcinoma cells by suppressing eIF4E-mediated oncogene translation via MNK inhibition.
Yang J, Li G, Huang Y, Liu Y
Toxicology and applied pharmacology 2023 May 1;466:116458
Toxicology and applied pharmacology 2023 May 1;466:116458
Taxol‑resistant breast cancer cell‑derived exosome‑delivered miR‑187‑5p regulates the growth of breast cancer cells via ABCD2 and Wnt/β‑catenin signaling.
Wu T, Zhu D, Wu X, Zhang N, Zhang Q
Oncology letters 2023 Mar;25(3):119
Oncology letters 2023 Mar;25(3):119
CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis.
Mo X, Shen X, Mo X, Yu F, Tan W, Deng Z, He J, Luo Z, Chen Z, Yang J
Biochemical pharmacology 2023 Mar;209:115446
Biochemical pharmacology 2023 Mar;209:115446
1,25(OH)(2) D(3) induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.
Erzurumlu Y, Aydogdu E, Dogan HK, Catakli D, Muhammed MT, Buyuksandic B
Cellular signalling 2023 Mar;103:110577
Cellular signalling 2023 Mar;103:110577
Oncogenes and Methionine Addiction of Cancer: Role of c-MYC.
Aoki Y, Han Q, Kubota Y, Masaki N, Obara K, Tome Y, Bouvet M, Nishida K, Hoffman RM
Cancer genomics & proteomics 2023 Mar-Apr;20(2):165-170
Cancer genomics & proteomics 2023 Mar-Apr;20(2):165-170
JQ-1/bortezomib combination strongly impairs MM and PEL survival by inhibiting c-Myc and mTOR despite the activation of prosurvival mechanisms.
Arena A, Romeo MA, Benedetti R, Gilardini Montani MS, Cirone M
Experimental hematology 2023 Mar-Apr;119-120:28-41
Experimental hematology 2023 Mar-Apr;119-120:28-41
Ursolic Acid Suppresses Colorectal Cancer by Down-Regulation of Wnt/β-Catenin Signaling Pathway Activity.
Zhao H, Tang S, Tao Q, Ming T, Lei J, Liang Y, Peng Y, Wang M, Liu M, Yang H, Ren S, Xu H
Journal of agricultural and food chemistry 2023 Mar 8;71(9):3981-3993
Journal of agricultural and food chemistry 2023 Mar 8;71(9):3981-3993
A novel feedback regulated loop of circRRM2-IGF2BP1-MYC promotes breast cancer metastasis.
Hao R, Zhang L, Si Y, Zhang P, Wang Y, Li B, Hu J, Qi Y
Cancer cell international 2023 Mar 25;23(1):54
Cancer cell international 2023 Mar 25;23(1):54
The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice.
Wu J, Bu D, Wang H, Shen D, Chong D, Zhang T, Tao W, Zhao M, Zhao Y, Fang L, Li P, Xue B, Li CJ
Nature communications 2023 Mar 24;14(1):1634
Nature communications 2023 Mar 24;14(1):1634
Discovery of Potent DYRK2 Inhibitors with High Selectivity, Great Solubility, and Excellent Safety Properties for the Treatment of Prostate Cancer.
Yuan K, Shen H, Zheng M, Xia F, Li Q, Chen W, Ji M, Yang H, Zhuang X, Cai Z, Min W, Wang X, Xiao Y, Yang P
Journal of medicinal chemistry 2023 Mar 23;66(6):4215-4230
Journal of medicinal chemistry 2023 Mar 23;66(6):4215-4230
A novel selective estrogen receptor degrader induces cell cycle arrest in breast cancer via ERα degradation and the autophagy-lysosome pathway.
Zhou J, Shen R, Liu J, Deng X, Xin L, Zhou HB, Huang J
Bioorganic & medicinal chemistry 2023 Mar 15;82:117235
Bioorganic & medicinal chemistry 2023 Mar 15;82:117235
Gold nanoparticles inhibit tumor growth via targeting the Warburg effect in a c-Myc-dependent way.
Sun L, Liu Y, Yang N, Ye X, Liu Z, Wu J, Zhou M, Zhong W, Cao M, Zhang J, Mequanint K, Xing M, Liao W
Acta biomaterialia 2023 Mar 1;158:583-598
Acta biomaterialia 2023 Mar 1;158:583-598
Dishevelled segment polarity protein 2 promotes gastric cancer progression through Wnt/β-catenin pathway.
He R, Chen Y, Qian C, Hu Y, Huang X, Tao R
Tissue & cell 2023 Jun;82:102119
Tissue & cell 2023 Jun;82:102119
Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells.
Erzurumlu Y, Catakli D, Dogan HK
Journal of natural medicines 2023 Jun;77(3):572-583
Journal of natural medicines 2023 Jun;77(3):572-583
Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling.
Wu H, Tang LX, Wang XM, Li LP, Chen XK, He YJ, Yang DZ, Shi Y, Shou JL, Zhang ZS, Wang L, Lu BJ, An SM, Zeng CY, Wang WE
Acta pharmacologica Sinica 2023 Jun;44(6):1149-1160
Acta pharmacologica Sinica 2023 Jun;44(6):1149-1160
METTL3-dependent m(6)A methylation facilitates uterine receptivity and female fertility via balancing estrogen and progesterone signaling.
Wan S, Sun Y, Zong J, Meng W, Yan J, Chen K, Wang S, Guo D, Xiao Z, Zhou Q, Yin Z, Yang M
Cell death & disease 2023 Jun 3;14(6):349
Cell death & disease 2023 Jun 3;14(6):349
SOX1 acts as a tumor hypnotist rendering nasopharyngeal carcinoma cells refractory to chemotherapy.
Lei XX, Wang SL, Xia Y, Yan M, He B, Wang B, Long ZJ, Liu Q
Cell death discovery 2023 Jun 27;9(1):194
Cell death discovery 2023 Jun 27;9(1):194
HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.
Ma H, Qi G, Han F, Gai P, Peng J, Kong B
Cell communication and signaling : CCS 2023 Jun 16;21(1):144
Cell communication and signaling : CCS 2023 Jun 16;21(1):144
Targeting SMYD2 inhibits prostate cancer cell growth by regulating c-Myc signaling.
Li J, Wan F, Zhang J, Zheng S, Yang Y, Hong Z, Dai B
Molecular carcinogenesis 2023 Jul;62(7):940-950
Molecular carcinogenesis 2023 Jul;62(7):940-950
eIF3a sustains non-small cell lung cancer stem cell-like properties by promoting YY1-mediated transcriptional activation of β-catenin.
Zheng JY, Zhu T, Zhuo W, Mao XY, Yin JY, Li X, He YJ, Zhang W, Liu C, Liu ZQ
Biochemical pharmacology 2023 Jul;213:115616
Biochemical pharmacology 2023 Jul;213:115616
Patch-clamp studies and cell viability assays suggest a distinct site for viroporin inhibitors on the E protein of SARS-CoV-2.
Breitinger U, Sedky CA, Sticht H, Breitinger HG
Virology journal 2023 Jul 8;20(1):142
Virology journal 2023 Jul 8;20(1):142
Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness.
He B, Gao R, Lv S, Chen A, Huang J, Wang L, Feng Y, Feng J, Liu B, Lei J, Deng B, He B, Cui B, Peng F, Yan M, Wang Z, Lam EW, Jin B, Shao Z, Li Y, Jiao J, Wang X, Liu Q
Signal transduction and targeted therapy 2023 Jul 19;8(1):275
Signal transduction and targeted therapy 2023 Jul 19;8(1):275
Hypoxia-cleavable and specific targeted nanomedicine delivers epigenetic drugs for enhanced treatment of breast cancer and bone metastasis.
Li Z, Liu P, Chen W, Liu X, Tong F, Sun J, Zhou Y, Lei T, Yang W, Ma D, Gao H, Qin Y
Journal of nanobiotechnology 2023 Jul 12;21(1):221
Journal of nanobiotechnology 2023 Jul 12;21(1):221
RNF106 aggravates esophageal squamous cell carcinoma progression through LATS2/YAP axis.
Sun Q, Lu H, Zhang W, Du Y, Liang Q, Zhang Y, Wu J, Zhong M
Archives of biochemistry and biophysics 2023 Jul 1;742:109640
Archives of biochemistry and biophysics 2023 Jul 1;742:109640
Targeting CDK12 obviates the malignant phenotypes of colorectal cancer through the Wnt/β-catenin signaling pathway.
Liu S, Wu J, Lu X, Guo C, Zheng Q, Wang Y, Hu Q, Bian S, Luo L, Cheng Q, Liu Z, Dai W
Experimental cell research 2023 Jul 1;428(1):113613
Experimental cell research 2023 Jul 1;428(1):113613
Stat3 shRNA delivery with folate receptor-modified multi-functionalized graphene oxide particles for combined infrared radiation and gene therapy in hepatocellular carcinoma.
Chen X, Zhang L, Wang X, Xu L, Sun J, Liu Y, Liu X, Kalvakolanu DV, Guo B
Anti-cancer drugs 2023 Jul 1;34(6):715-724
Anti-cancer drugs 2023 Jul 1;34(6):715-724
CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1.
Li D, Wang Y, Dong C, Chen T, Dong A, Ren J, Li W, Shu G, Yang J, Shen W, Qin L, Hu L, Zhou J
Oncogene 2023 Jan;42(2):83-98
Oncogene 2023 Jan;42(2):83-98
Ubiquitin-specific peptidase 14 maintains estrogen receptor α stability via its deubiquitination activity in endometrial cancer.
Su Y, Zeng K, Liu S, Wu Y, Wang C, Wang S, Lin L, Zou R, Sun G, Luan R, Zhou B, Bai Y, Niu J, Zhang Y, Zhao Y
The Journal of biological chemistry 2023 Jan;299(1):102734
The Journal of biological chemistry 2023 Jan;299(1):102734
Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease.
Ren Y, Zhu X, Fu K, Zhang H, Zhao W, Lin Y, Fang Q, Wang J, Chen Y, Guo D
Biochemical pharmacology 2023 Jan;207:115355
Biochemical pharmacology 2023 Jan;207:115355
Dietary selenium excess affected spermatogenesis via DNA damage and telomere-related cell senescence and apoptosis in mice.
Zhang Y, Liu J, Li X, Zhou G, Sang Y, Zhang M, Gao L, Xue J, Zhao M, Yu H, Zhou X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jan;171:113556
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jan;171:113556
Pattern recognition receptor mediated innate immune response requires a Rif-dependent pathway.
Tian X, Nanding K, Dai X, Wang Q, Wang J, Morigen, Fan L
Journal of autoimmunity 2023 Jan;134:102975
Journal of autoimmunity 2023 Jan;134:102975
Immune responses of hemocytes in the blood clam Tegillarca granosa in response to in vivo Vibrio harveyi infection.
Yang Q, Xiao G, Chen R, Huang X, Teng S
Fish & shellfish immunology 2023 Jan;132:108447
Fish & shellfish immunology 2023 Jan;132:108447
Molecular Mechanism of Adenovirus Late Protein L4-100K Chaperones the Trimerization of Hexon.
Zhu R, Xu XG, Zhang TX, Wang XP, Zhang CH, Wang CY, Wang C, Wu JX, Yu B, Yu XH
Journal of virology 2023 Jan 31;97(1):e0146722
Journal of virology 2023 Jan 31;97(1):e0146722
USP39 stabilizes β-catenin by deubiquitination and suppressing E3 ligase TRIM26 pre-mRNA maturation to promote HCC progression.
Wang W, Lei Y, Zhang G, Li X, Yuan J, Li T, Zhong W, Zhang Y, Tan X, Song G
Cell death & disease 2023 Jan 27;14(1):63
Cell death & disease 2023 Jan 27;14(1):63
B7-H6 enhances F-actin rearrangement by targeting c-MYC activation to promote medulloblastoma migration and invasion.
Fan J, Wang Y, Liang X, Peng Y, Li S, Li X, Zhou F, Li Y
Medical oncology (Northwood, London, England) 2023 Jan 24;40(3):85
Medical oncology (Northwood, London, England) 2023 Jan 24;40(3):85
Targeting Tumor Hypoxia Inhibits Aggressive Phenotype of Dedifferentiated Thyroid Cancer.
Ma B, Wen S, Luo Y, Zhang T, Yang Y, Shen C, Zhang Y, Ji Q, Qu N, Wang Y
The Journal of clinical endocrinology and metabolism 2023 Jan 17;108(2):368-384
The Journal of clinical endocrinology and metabolism 2023 Jan 17;108(2):368-384
Bisphenol A and Di(2-Ethylhexyl) Phthalate promote pulmonary carcinoma in female rats via estrogen receptor beta: In vivo and in silico analysis.
Xiao M, Zhang Y, Zhang X, Zhang G, Jin C, Yang J, Wu S, Lu X
Ecotoxicology and environmental safety 2023 Jan 15;250:114496
Ecotoxicology and environmental safety 2023 Jan 15;250:114496
CJ(2): A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane.
Fan R, Deng A, Qi B, Zhang S, Sang R, Luo L, Gou J, Liu Y, Lin R, Zhao M, Liu Y, Yang L, Cheng M, Wei G
Journal of medicinal chemistry 2023 Jan 12;66(1):875-889
Journal of medicinal chemistry 2023 Jan 12;66(1):875-889
Myc-mediated circular RNA circMcph1/miR-370-3p/Irak2 axis is a progressive regulator in hepatic fibrosis.
Xu JJ, Chen X, Zhu S, Jiang LF, Ma WX, Chen SY, Meng XM, Huang C, Li J
Life sciences 2023 Jan 1;312:121182
Life sciences 2023 Jan 1;312:121182
Identification of non-coding RNAs and their functional network associated with optic nerve invasion in retinoblastoma.
Sun J, Gan L, Ding J, Ma R, Qian J, Xue K
Heliyon 2023 Feb;9(2):e13813
Heliyon 2023 Feb;9(2):e13813
CRISPR-Cas9-Mediated NPC1 Gene Deletion Enhances HEK 293 T Cell Adhesion by Regulating E-Cadherin.
Jia Z, Yang M, Zhao Y, Li X, Yang C, Qiao L, Li H, Du J, Lin J, Guan L
Molecular biotechnology 2023 Feb;65(2):252-262
Molecular biotechnology 2023 Feb;65(2):252-262
POR overexpression induces tamoxifen-resistance in breast cancer through the STAT1/c-Myc pathway.
Chen S, Wu D, Liu Q, Jin F, Yao F, Fang Y
Molecular carcinogenesis 2023 Feb;62(2):249-260
Molecular carcinogenesis 2023 Feb;62(2):249-260
MiR-138-5p suppresses the progression of lung cancer by targeting SNIP1.
Wu J, Han X, Yang X, Li Y, Liang Y, Sun G, Wang R, Wang P, Xie S, Feng J, Sun H
Thoracic cancer 2023 Feb;14(6):612-623
Thoracic cancer 2023 Feb;14(6):612-623
Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia.
Feng Y, Han Y, Hu A, Qu Y, Hu Y, Wu H, Wang X, He L
Acta pharmaceutica Sinica. B 2023 Feb;13(2):598-617
Acta pharmaceutica Sinica. B 2023 Feb;13(2):598-617
Resveratrol suppresses lung cancer by targeting cancer stem-like cells and regulating tumor microenvironment.
Xie C, Liang C, Wang R, Yi K, Zhou X, Li X, Chen Y, Miao D, Zhong C, Zhu J
The Journal of nutritional biochemistry 2023 Feb;112:109211
The Journal of nutritional biochemistry 2023 Feb;112:109211
The Prognostic Value and the Oncogenic and Immunological Roles of Vacuolar Protein Sorting Associated Protein 26 A in Pancreatic Adenocarcinoma.
Hou J, Wu H, Xu B, Shang J, Xu X, Li G, Zhang H, Zhang W, Deng Y, Hong X, Hu T, Zhang M, Zhan Y
International journal of molecular sciences 2023 Feb 9;24(4)
International journal of molecular sciences 2023 Feb 9;24(4)
A program of successive gene expression in mouse one-cell embryos.
Asami M, Lam BYH, Hoffmann M, Suzuki T, Lu X, Yoshida N, Ma MK, Rainbow K, Gužvić M, VerMilyea MD, Yeo GSH, Klein CA, Perry ACF
Cell reports 2023 Feb 28;42(2):112023
Cell reports 2023 Feb 28;42(2):112023
Caprin-1 plays a role in cell proliferation and Warburg metabolism of esophageal carcinoma by regulating METTL3 and WTAP.
Gao Y, Yuan L, Ke C, Pei Z, Liu X, Wu R, Kui X, Zhang Y
Journal of translational medicine 2023 Feb 28;21(1):159
Journal of translational medicine 2023 Feb 28;21(1):159
LncGMDS-AS1 promotes the tumorigenesis of colorectal cancer through HuR-STAT3/Wnt axis.
Ye D, Liu H, Zhao G, Chen A, Jiang Y, Hu Y, Liu D, Xie N, Liang W, Chen X, Zhang H, Li C, Wang J, Sun D, Chen W, Tan D, Wang Q, Wang H, Yu D, Wu B, Wang M, Cui S, Liu S, Zhang X
Cell death & disease 2023 Feb 27;14(2):165
Cell death & disease 2023 Feb 27;14(2):165
mcPGK1-dependent mitochondrial import of PGK1 promotes metabolic reprogramming and self-renewal of liver TICs.
Chen Z, He Q, Lu T, Wu J, Shi G, He L, Zong H, Liu B, Zhu P
Nature communications 2023 Feb 27;14(1):1121
Nature communications 2023 Feb 27;14(1):1121
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
Zhou C, Zhu X, Liu N, Dong X, Zhang X, Huang H, Tang Y, Liu S, Hu M, Wang M, Deng X, Li S, Zhang R, Huang Y, Lyu H, Xiao S, Luo S, Ali DW, Michalak M, Chen XZ, Wang Z, Tang J
Signal transduction and targeted therapy 2023 Feb 17;8(1):66
Signal transduction and targeted therapy 2023 Feb 17;8(1):66
Luteoloside Induces G0/G1 Phase Arrest of Neuroblastoma Cells by Targeting p38 MAPK.
He Y, Luo M, Lei S, Zeng Z, Chen T, Wu Y, Wang D, Wang L, Wang L
Molecules (Basel, Switzerland) 2023 Feb 12;28(4)
Molecules (Basel, Switzerland) 2023 Feb 12;28(4)
Tripartite motif containing 33 demonstrated anticancer effect by degrading c‑Myc: Limitation of glutamine metabolism and proliferation in endometrial carcinoma cells.
Qi Y, Ma N, Zhang J
International journal of oncology 2023 Dec;63(6)
International journal of oncology 2023 Dec;63(6)
Classical swine fever virus NS5A protein antagonizes innate immune response by inhibiting the NF-κB signaling.
Sun J, Li J, Li L, Yu H, Ma P, Wang Y, Zhu J, Feng Z, Tu C
Virologica Sinica 2023 Dec;38(6):900-910
Virologica Sinica 2023 Dec;38(6):900-910
The Combination of Methioninase and Ethionine Exploits Methionine Addiction to Selectively Eradicate Osteosarcoma Cells and Not Normal Cells and Synergistically Down-regulates the Expression of C-MYC.
Aoki Y, Kubota Y, Han Q, Masaki N, Obara K, Bouvet M, Chawla SP, Tome Y, Nishida K, Hoffman RM
Cancer genomics & proteomics 2023 Dec;20(6suppl):679-685
Cancer genomics & proteomics 2023 Dec;20(6suppl):679-685
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
Cui L, Lu Y, Zheng J, Guo B, Zhao X
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
Design, synthesis, and biological evaluation of novel 4,4'-bipyridine derivatives acting as CDK9-Cyclin T1 protein-protein interaction inhibitors against triple-negative breast cancer.
Gao G, Li J, Cao Y, Li X, Qian Y, Wang X, Li M, Qiu Y, Wu T, Wang L, Fang M
European journal of medicinal chemistry 2023 Dec 5;261:115858
European journal of medicinal chemistry 2023 Dec 5;261:115858
RNA-binding motif protein 10 inactivates c-Myc by partnering with ribosomal proteins uL18 and uL5.
Lee H, Jung JH, Ko HM, Park H, Segall AM, Sheffmaker RL, Wang J, Frey WD, Pham N, Wang Y, Zhang Y, Jackson JG, Zeng SX, Lu H
Proceedings of the National Academy of Sciences of the United States of America 2023 Dec 5;120(49):e2308292120
Proceedings of the National Academy of Sciences of the United States of America 2023 Dec 5;120(49):e2308292120
ESM1 Interacts with c-Met to Promote Gastric Cancer Peritoneal Metastasis by Inducing Angiogenesis.
Yang J, Shu G, Chen T, Dong A, Dong C, Li W, Sun X, Zhou Y, Li D, Zhou J
Cancers 2023 Dec 30;16(1)
Cancers 2023 Dec 30;16(1)
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Bao H, Peng Z, Cheng X, Jian C, Li X, Shi Y, Zhu W, Hu Y, Jiang M, Song J, Fang F, Chen J, Shu X
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stability.
Wang Z, Cai H, Li Z, Sun W, Zhao E, Cui H
Clinical epigenetics 2023 Dec 13;15(1):192
Clinical epigenetics 2023 Dec 13;15(1):192
AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer.
Tian W, Tang Y, Luo Y, Xie J, Zheng S, Zou Y, Huang X, Wu L, Zhang J, Sun Y, Tang H, Du W, Li X, Xie X
Cell death & disease 2023 Dec 1;14(12):790
Cell death & disease 2023 Dec 1;14(12):790
Hydrogel-based miR-192 delivery inhibits the development of hepatocellular carcinoma by suppressing the GSK3β/Wnt/β-catenin pathway.
Yang Q, Zhuge X, Lin W, Yu W, Zhu Y, Shi C, Shi Z
Neoplasma 2023 Aug;70(4):555-565
Neoplasma 2023 Aug;70(4):555-565
NDRG3 regulates imatinib resistance by promoting β‑catenin accumulation in the nucleus in chronic myelogenous leukemia.
Wang X, Rong S, Sun Y, Yin B, Yang X, Lu X, Sun H, Yan Y, Sun G, Liang Y, Wang P, Xie S, Li Y
Oncology reports 2023 Aug;50(2)
Oncology reports 2023 Aug;50(2)
USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.
Zhong B, Zhu Q, Wang L, Wang F, Zheng Y, Lin S, Cheng X
Cell biology international 2023 Aug;47(8):1368-1380
Cell biology international 2023 Aug;47(8):1368-1380
Phosphorylated PTTG1 switches its subcellular distribution and promotes β-catenin stabilization and subsequent transcription activity.
Zhang X, Wu N, Huang H, Li S, Liu S, Zhang R, Huang Y, Lyu H, Xiao S, Ali DW, Michalak M, Chen XZ, Zhou C, Tang J
Oncogene 2023 Aug;42(32):2439-2455
Oncogene 2023 Aug;42(32):2439-2455
PPARγ agonist inhibits c-Myc-mediated colorectal cancer tumor immune escape.
Xu L, Che S, Chen H, Liu Q, Shi J, Jin J, Hou Y
Journal of cellular biochemistry 2023 Aug;124(8):1145-1154
Journal of cellular biochemistry 2023 Aug;124(8):1145-1154
221S-1a inhibits endothelial proliferation in pathological angiogenesis through ERK/c-Myc signaling.
Yao X, Xue Y, Ma Q, Bai Y, Jia P, Zhang Y, Lai B, He S, Ma Q, Zhang J, Tian H, Yin Q, Zheng X, Zheng X
European journal of pharmacology 2023 Aug 5;952:175805
European journal of pharmacology 2023 Aug 5;952:175805
Histone acetylation by HBO1 (KAT7) activates Wnt/β-catenin signaling to promote leukemogenesis in B-cell acute lymphoblastic leukemia.
Wang H, Qiu Y, Zhang H, Chang N, Hu Y, Chen J, Hu R, Liao P, Li Z, Yang Y, Cen Q, Ding X, Li M, Xie X, Li Y
Cell death & disease 2023 Aug 4;14(8):498
Cell death & disease 2023 Aug 4;14(8):498
SUMOylation of SMAD4 by PIAS1 in Conjunction with Vimentin Upregulation Promotes Migration Potential in Non-Small Cell Lung Cancer.
Wu C, Zhu X, Dai Q, Chu Z, Yang S, Dong Z
Frontiers in bioscience (Landmark edition) 2023 Aug 31;28(8):192
Frontiers in bioscience (Landmark edition) 2023 Aug 31;28(8):192
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
Jia Y, Huang X, Shi H, Wang M, Chen J, Zhang H, Hou D, Jing H, Du J, Han H, Zhang J
Experimental cell research 2023 Aug 15;429(2):113629
Experimental cell research 2023 Aug 15;429(2):113629
CD58 acts as a tumor promotor in hepatocellular carcinoma via activating the AKT/GSK-3β/β-catenin pathway.
Wang C, Cao F, Cao J, Jiao Z, You Y, Xiong Y, Zhao W, Wang X
Journal of translational medicine 2023 Aug 12;21(1):539
Journal of translational medicine 2023 Aug 12;21(1):539
Deletion of the tyrosine phosphatase Shp2 in cervical cancer cells promotes reprogramming of glutamine metabolism.
Gao X, Kang J, Li X, Chen C, Luo D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22880
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22880
Exosomes incorporated with black phosphorus quantum dots attenuate retinal angiogenesis via disrupting glucose metabolism.
Gui X, Zhang H, Zhang R, Li Q, Zhu W, Nie Z, Zhao J, Cui X, Hao W, Wen X, Shen W, Song H
Materials today. Bio 2023 Apr;19:100602
Materials today. Bio 2023 Apr;19:100602
[High expression of MYH9 inhibits apoptosis of non-small cell lung cancer cells through activating the AKT/c-Myc pathway].
Liu F, Peng L, Xi J
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Apr 20;43(4):527-536
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Apr 20;43(4):527-536
Hyperthermia inhibits growth of nasopharyngeal carcinoma through degradation of c-Myc.
Li X, Duan S, Zheng Y, Yang Y, Wang L, Li X, Zhang Q, Thorne RF, Li W, Yang D
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2022;39(1):358-371
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2022;39(1):358-371
Ubiquitination and degradation of MGMT by TRIM72 increases the sensitivity of uveal melanoma cells to Dacarbazine treatment.
Li X, Yang C, Luo N, Yang Y, Guo Y, Chen P, Cun B
Cancer biomarkers : section A of Disease markers 2022;34(2):275-284
Cancer biomarkers : section A of Disease markers 2022;34(2):275-284
PHGDH Inhibitor CBR-5884 Inhibits Epithelial Ovarian Cancer Progression via ROS/Wnt/β-Catenin Pathway and Plays a Synergistic Role with PARP Inhibitor Olaparib.
Zhang X, Sun M, Jiao Y, Lin B, Yang Q
Oxidative medicine and cellular longevity 2022;2022:9029544
Oxidative medicine and cellular longevity 2022;2022:9029544
Total Saponins of Radix Clematis Regulate Fibroblast-Like Synoviocyte Proliferation in Rheumatoid Arthritis via the LncRNA OIP5-AS1/MiR-410-3p/Wnt7b Signaling Pathway.
Pan L, Sun Y, Jiang H, Chen Y, Jiang Y, Han Y, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8393949
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8393949
ATF4/MYC Regulates MTHFD2 to Promote NSCLC Progression by Mediating Redox Homeostasis.
Gao Y, Feng L, Zhang L, Geng J, Zhang E
Disease markers 2022;2022:7527996
Disease markers 2022;2022:7527996
Resveratrol Downregulates miR-155-5p to Block the Malignant Behavior of Gastric Cancer Cells.
Su N, Li L, Zhou E, Li H, Wu S, Cao Z
BioMed research international 2022;2022:6968641
BioMed research international 2022;2022:6968641
Fufang Xueshuantong Improves Diabetic Cardiomyopathy by Regulating the Wnt/β-Catenin Pathway.
Peng M, Liu H, Ji Q, Ma P, Niu Y, Ning S, Sun H, Pang X, Yang Y, Zhang Y, Han J, Hao G
International journal of endocrinology 2022;2022:3919161
International journal of endocrinology 2022;2022:3919161
FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A.
Wang X, Li Y, Li Y, Liu P, Liu S, Pan Y
Stem cells international 2022;2022:3242482
Stem cells international 2022;2022:3242482
Intervention Mechanism of Hunag-Lian Jie-Du Decoction on Canonical Wnt/β-Catenin Signaling Pathway in Psoriasis Mouse Model.
Yang X, Luo G, Fu L, Huang H, Wang L, Yin L, Zhang X, Wang T, Ma X, Feng T, Ye J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3193572
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3193572
Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.
Ma L, Shen T, Peng H, Wu J, Wang W, Gao X
Journal of oncology 2022;2022:2352360
Journal of oncology 2022;2022:2352360
Therapeutical Significance of Serpina3n Subsequent Cerebral Ischemia via Cytotoxic Granzyme B Inactivation.
Aslam MS, Aslam MS, Aslam KS, Iqbal A, Yuan L
BioMed research international 2022;2022:1557010
BioMed research international 2022;2022:1557010
HERC3 directly targets RPL23A for ubiquitination degradation and further regulates Colorectal Cancer proliferation and the cell cycle.
Zhang Z, Wu Q, Fang M, Liu Y, Jiang J, Feng Q, Hu R, Xu J
International journal of biological sciences 2022;18(8):3282-3297
International journal of biological sciences 2022;18(8):3282-3297
HJURP Promotes Malignant Progression and Mediates Sensitivity to Cisplatin and WEE1-inhibitor in Serous Ovarian Cancer.
Dou Z, Qiu C, Zhang X, Yao S, Zhao C, Wang Z, Chu R, Chen J, Chen Z, Li R, Wang K, Liu P, Liu C, Song K, Kong B
International journal of biological sciences 2022;18(3):1188-1210
International journal of biological sciences 2022;18(3):1188-1210
TBL1X and Flot2 form a positive feedback loop to promote metastasis in nasopharyngeal carcinoma.
Xu H, Yan X, Zhu H, Kang Y, Luo W, Zhao J, Zhou K, Liu X, Ye L, Zhou Q, Li S, Zhao M, Wang L, Zhu B, Liu W, Li J, Jiang X, Ren C
International journal of biological sciences 2022;18(3):1134-1149
International journal of biological sciences 2022;18(3):1134-1149
GALNT1 Enhances Malignant Phenotype of Gastric Cancer via Modulating CD44 Glycosylation to Activate the Wnt/β-catenin Signaling Pathway.
Zhang J, Wang H, Wu J, Yuan C, Chen S, Liu S, Huo M, Zhang C, He Y
International journal of biological sciences 2022;18(16):6068-6083
International journal of biological sciences 2022;18(16):6068-6083
CCDC65, a Gene Knockout that leads to Early Death of Mice, acts as a potentially Novel Tumor Suppressor in Lung Adenocarcinoma.
Zhang Z, Xu P, Hu Z, Fu Z, Deng T, Deng X, Peng L, Xie Y, Long L, Zheng D, Shen P, Zhang M, Gong B, Zhu Z, Lin J, Chen R, Liu Z, Yang H, Li R, Fang W
International journal of biological sciences 2022;18(10):4171-4186
International journal of biological sciences 2022;18(10):4171-4186
CSTF2 Acts as a Prognostic Marker Correlated with Immune Infiltration in Hepatocellular Carcinoma.
Zhang W, Wan Y, Zhang Y, Liu Q, Zhu X
Cancer management and research 2022;14:2691-2709
Cancer management and research 2022;14:2691-2709
Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer.
Boos SL, Loevenich LP, Vosberg S, Engleitner T, Öllinger R, Kumbrink J, Rokavec M, Michl M, Greif PA, Jung A, Hermeking H, Neumann J, Kirchner T, Rad R, Jung P
Cellular and molecular gastroenterology and hepatology 2022;13(2):517-540
Cellular and molecular gastroenterology and hepatology 2022;13(2):517-540
EST12 regulates Myc expression and enhances anti-mycobacterial inflammatory response via RACK1-JNK-AP1-Myc immune pathway.
Wu J, Luo FL, Xie Y, Xiong H, Gao Y, Liu G, Zhang XL
Frontiers in immunology 2022;13:943174
Frontiers in immunology 2022;13:943174
Norcantharidin overcomes vemurafenib resistance in melanoma by inhibiting pentose phosphate pathway and lipogenesis via downregulating the mTOR pathway.
Wang L, Otkur W, Wang A, Wang W, Lyu Y, Fang L, Shan X, Song M, Feng Y, Zhao Y, Piao HL, Qi H, Liu JW
Frontiers in pharmacology 2022;13:906043
Frontiers in pharmacology 2022;13:906043
Matrine, a potential c-Myc inhibitor, suppresses ribosome biogenesis and nucleotide metabolism in myeloid leukemia.
Zhong WJ, Ma L, Yang F, Cao J, Tan J, Li B
Frontiers in pharmacology 2022;13:1027441
Frontiers in pharmacology 2022;13:1027441
A novel HCC prognosis predictor PDSS1 affects the cell cycle through the STAT3 signaling pathway in HCC.
Rao Z, Li H, Yao W, Wang Q, Ma B, Xue D, Meng X
Frontiers in oncology 2022;12:927468
Frontiers in oncology 2022;12:927468
Overexpression of SFXN1 indicates poor prognosis and promotes tumor progression in lung adenocarcinoma.
Chen L, Kang Y, Jiang Y, You J, Huang C, Xu X, Chen F
Pathology, research and practice 2022 Sep;237:154031
Pathology, research and practice 2022 Sep;237:154031
Vitamin D receptor enhances NLRC4 inflammasome activation by promoting NAIPs-NLRC4 association.
Chen X, Zhang Z, Sun N, Li J, Ma Z, Rao Z, Sun X, Zeng Q, Wu Y, Li J, Zhang J, Chen Y
EMBO reports 2022 Sep 5;23(9):e54611
EMBO reports 2022 Sep 5;23(9):e54611
MARCH1 promotes the growth and maintaining of stem cell-like characteristics of gastric cancer cells by activating the Wnt/β-catenin signaling pathway.
Liang W, Zhang T, Huo J, Yang J
Tissue & cell 2022 Oct;78:101895
Tissue & cell 2022 Oct;78:101895
PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop.
Zhao X, Shu D, Sun W, Si S, Ran W, Guo B, Cui L
Cancer communications (London, England) 2022 Oct;42(10):987-1007
Cancer communications (London, England) 2022 Oct;42(10):987-1007
Identification of Trovafloxacin, Ozanimod, and Ozenoxacin as Potent c-Myc G-Quadruplex Stabilizers to Suppress c-Myc Transcription and Myeloma Growth.
Zhang J, Wang T, Geng X, Liu L, Gao J
Molecular informatics 2022 Oct;41(10):e2200011
Molecular informatics 2022 Oct;41(10):e2200011
The HN1/HMGB1 axis promotes the proliferation and metastasis of hepatocellular carcinoma and attenuates the chemosensitivity to oxaliplatin.
Wang R, Fu Y, Yao M, Cui X, Zhao Y, Lu X, Li Y, Lin Y, He S
The FEBS journal 2022 Oct;289(20):6400-6419
The FEBS journal 2022 Oct;289(20):6400-6419
tRNA-m(1)A modification promotes T cell expansion via efficient MYC protein synthesis.
Liu Y, Zhou J, Li X, Zhang X, Shi J, Wang X, Li H, Miao S, Chen H, He X, Dong L, Lee GR, Zheng J, Liu RJ, Su B, Ye Y, Flavell RA, Yi C, Wu Y, Li HB
Nature immunology 2022 Oct;23(10):1433-1444
Nature immunology 2022 Oct;23(10):1433-1444
Skin chronological aging drives age-related bone loss via secretion of cystatin-A.
Liang W, Chen Q, Cheng S, Wei R, Li Y, Yao C, Ouyang Z, Kang D, Chen A, Liu Z, Li K, Bai X, Li Q, Huang B
Nature aging 2022 Oct;2(10):906-922
Nature aging 2022 Oct;2(10):906-922
Structure-based discovery of Licoflavone B and Ginkgetin targeting c-Myc G-quadruplex to suppress c-Myc transcription and myeloma growth.
Liu L, Geng X, Zhang J, Li S, Gao J
Chemical biology & drug design 2022 Oct;100(4):525-533
Chemical biology & drug design 2022 Oct;100(4):525-533
c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway.
Romeo MA, Gilardini Montani MS, Arena A, Benedetti R, D'Orazi G, Cirone M
Biomedicines 2022 Oct 5;10(10)
Biomedicines 2022 Oct 5;10(10)
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.
Wen P, Wang H, Li Y, Sui X, Hou Z, Guo X, Xue W, Liu D, Wang Y, Gao J
Cell communication and signaling : CCS 2022 Oct 28;20(1):170
Cell communication and signaling : CCS 2022 Oct 28;20(1):170
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
Tian H, Chen Z, Zhu X, Ou Q, Wang Z, Wu B, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Lu L, Xu GT
iScience 2022 Oct 21;25(10):105050
iScience 2022 Oct 21;25(10):105050
CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway.
Zhang X, Tian L, Li Z, Liu R, Yu J, Liu B
Biochemical and biophysical research communications 2022 Oct 20;626:220-228
Biochemical and biophysical research communications 2022 Oct 20;626:220-228
RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway.
Xu J, Shi P, Xia F, Zhao X, Chen J, Geng R, Cui H, Yang L
International journal of molecular sciences 2022 Oct 10;23(19)
International journal of molecular sciences 2022 Oct 10;23(19)
Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma.
Chen X, Liu Q, Chen Y, Wang L, Yang R, Zhang W, Pan X, Zhang S, Chen C, Wu T, Xia J, Cheng B, Chen X, Ren X
Molecular metabolism 2022 Nov;65:101600
Molecular metabolism 2022 Nov;65:101600
Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting β-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis.
Yang J, Miao RR, Li YN, Pan T, Wu SH, Qu XJ, Cui SX
Acta pharmacologica Sinica 2022 Nov;43(11):2967-2976
Acta pharmacologica Sinica 2022 Nov;43(11):2967-2976
Babao Dan Alleviates 5-Fluorouracil-Induced Intestinal Damage via Wnt/β-Catenin Pathway.
Gui MX, Huang B, Peng J, Chen X, Muthu R, Gao Y, Wang RG, Lin JM
Chinese journal of integrative medicine 2022 Nov;28(11):1000-1006
Chinese journal of integrative medicine 2022 Nov;28(11):1000-1006
USP17L2-SIRT7 axis regulates DNA damage repair and chemoresistance in breast cancer cells.
Su Y, Wu C, Chang Y, Li L, Chen Y, Jia X, Wang X, Lv Y, Yu B, Yuan J
Breast cancer research and treatment 2022 Nov;196(1):31-44
Breast cancer research and treatment 2022 Nov;196(1):31-44
A dynamic fluorescence probed glycolysis suppression process in HeLa cells treated with trichostatin A.
Zhang F, Shao C, Wu Y, Zhao W, Jing X, Fang C, Huang Q
The Analyst 2022 Nov 7;147(22):5082-5090
The Analyst 2022 Nov 7;147(22):5082-5090
Cross-regulome profiling of RNA polymerases highlights the regulatory role of polymerase III on mRNA transcription by maintaining local chromatin architecture.
Jiang Y, Huang J, Tian K, Yi X, Zheng H, Zhu Y, Guo T, Ji X
Genome biology 2022 Nov 28;23(1):246
Genome biology 2022 Nov 28;23(1):246
Amination Potentially Augments the Ameliorative Effect of Curcumin on Inhibition of the IL-6/Stat3/c-Myc Pathway and Gut Microbial Modulation in Colitis-Associated Tumorigenesis.
Koh YC, Tsai YW, Lee PS, Nagabhushanam K, Ho CT, Pan MH
Journal of agricultural and food chemistry 2022 Nov 23;70(46):14744-14754
Journal of agricultural and food chemistry 2022 Nov 23;70(46):14744-14754
PSMA1 mediates tumor progression and poor prognosis of gastric carcinoma by deubiquitinating and stabilizing TAZ.
Yang Q, Lu Y, Shangguan J, Shu X
Cell death & disease 2022 Nov 23;13(11):989
Cell death & disease 2022 Nov 23;13(11):989
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway.
Zhang H, Liu J, Dang Q, Wang X, Chen J, Lin X, Yang N, Du J, Shi H, Liu Y, Han J
BMC molecular and cell biology 2022 Nov 16;23(1):48
BMC molecular and cell biology 2022 Nov 16;23(1):48
G protein subunit gamma 5 promotes the proliferation, metastasis and glycolysis of breast cancer cells through the Wnt/β-catenin pathway.
Yuan Z, Ren R, Xu Z
Anti-cancer drugs 2022 Nov 1;33(10):1004-1011
Anti-cancer drugs 2022 Nov 1;33(10):1004-1011
Bufalin Inhibits Tumorigenesis, Stemness, and Epithelial-Mesenchymal Transition in Colorectal Cancer through a C-Kit/Slug Signaling Axis.
Ding L, Yang Y, Lu Q, Qu D, Chandrakesan P, Feng H, Chen H, Chen X, Liao Z, Du J, Cao Z, Weygant N
International journal of molecular sciences 2022 Nov 1;23(21)
International journal of molecular sciences 2022 Nov 1;23(21)
SiNiSan alleviates liver injury by promoting hepatic stem cell differentiation via Wnt/β-catenin signaling pathway.
Xu W, Du X, Li J, Zhang Z, Ma X, Luo D, Xiao M, Sun Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153969
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153969
Jumonji-C domain-containing protein 5 suppresses proliferation and aerobic glycolysis in pancreatic cancer cells in a c-Myc-dependent manner.
Wang H, Wang J, Liu J, Wang Y, Xia G, Huang X
Cellular signalling 2022 May;93:110282
Cellular signalling 2022 May;93:110282
Heterozygote loss-of-function variants in the LRP5 gene cause familial exudative vitreoretinopathy.
Zhao R, Wang S, Zhao P, Dai E, Zhang X, Peng L, He Y, Yang M, Li S, Yang Z
Clinical & experimental ophthalmology 2022 May;50(4):441-448
Clinical & experimental ophthalmology 2022 May;50(4):441-448
Guanylate-binding Protein 2 Expression Is Associated With Poor Survival and Malignancy in Clear-cell Renal Cell Carcinoma.
Liu Q, Hoffman RM, Song J, Miao S, Zhang J, Ding D, Wang D
Anticancer research 2022 May;42(5):2341-2354
Anticancer research 2022 May;42(5):2341-2354
Therapeutic targeting of the mevalonate-geranylgeranyl diphosphate pathway with statins overcomes chemotherapy resistance in small cell lung cancer.
Guo C, Wan R, He Y, Lin SH, Cao J, Qiu Y, Zhang T, Zhao Q, Niu Y, Jin Y, Huang HY, Wang X, Tan L, Thomas RK, Zhang H, Chen L, Wong KK, Hu L, Ji H
Nature cancer 2022 May;3(5):614-628
Nature cancer 2022 May;3(5):614-628
Venetoclax enhances DNA damage induced by XPO1 inhibitors: A novel mechanism underlying the synergistic antileukaemic effect in acute myeloid leukaemia.
Yu H, Wu S, Liu S, Li X, Gai Y, Lin H, Wang Y, Edwards H, Ge Y, Wang G
Journal of cellular and molecular medicine 2022 May;26(9):2646-2657
Journal of cellular and molecular medicine 2022 May;26(9):2646-2657
Urea transporter B downregulates polyamines levels in melanoma B16 cells via p53 activation.
Li J, Sun Y, Yan R, Wu X, Zou H, Meng Y
Biochimica et biophysica acta. Molecular cell research 2022 May;1869(5):119236
Biochimica et biophysica acta. Molecular cell research 2022 May;1869(5):119236
FL118, acting as a 'molecular glue degrader', binds to dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c-Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy.
Ling X, Wu W, Aljahdali IAM, Liao J, Santha S, Fountzilas C, Boland PM, Li F
Clinical and translational medicine 2022 May;12(5):e881
Clinical and translational medicine 2022 May;12(5):e881
Mitochondrial GCN5L1 regulates glutaminase acetylation and hepatocellular carcinoma.
Zhang T, Cui Y, Wu Y, Meng J, Han L, Zhang J, Zhang C, Yang C, Chen L, Bai X, Zhang K, Wu K, Sack MN, Wang L, Zhu L
Clinical and translational medicine 2022 May;12(5):e852
Clinical and translational medicine 2022 May;12(5):e852
CYP2E1 plays a suppressive role in hepatocellular carcinoma by regulating Wnt/Dvl2/β-catenin signaling.
Zhu L, Yang X, Feng J, Mao J, Zhang Q, He M, Mi Y, Mei Y, Jin G, Zhang H
Journal of translational medicine 2022 May 4;20(1):194
Journal of translational medicine 2022 May 4;20(1):194
Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability.
Yao R, Zhang M, Zhou J, Liu L, Zhang Y, Gao J, Xu K
Cell communication and signaling : CCS 2022 May 26;20(1):73
Cell communication and signaling : CCS 2022 May 26;20(1):73
UHMK1 aids colorectal cancer cell proliferation and chemoresistance through augmenting IL-6/STAT3 signaling.
Gao X, Bao W, Bai J, Fan K, Li L, Li Y
Cell death & disease 2022 May 2;13(5):424
Cell death & disease 2022 May 2;13(5):424
Infectious Bronchitis Virus Nsp14 Degrades JAK1 to Inhibit the JAK-STAT Signaling Pathway in HD11 Cells.
Ma P, Gu K, Li H, Zhao Y, Li C, Wen R, Zhou C, Lei C, Yang X, Wang H
Viruses 2022 May 14;14(5)
Viruses 2022 May 14;14(5)
O-GlcNAc modification mediates aquaporin 3 to coordinate endometrial cell glycolysis and affects embryo implantation.
Zhang H, Qi J, Pei J, Zhang M, Shang Y, Li Z, Wang Y, Guo J, Sun K, Fan J, Sui L, Xu Y, Kong L, Kong Y
Journal of advanced research 2022 Mar;37:119-131
Journal of advanced research 2022 Mar;37:119-131
lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus.
Liu HT, Zou YX, Zhu WJ, Sen-Liu, Zhang GH, Ma RR, Guo XY, Gao P
Cell death and differentiation 2022 Mar;29(3):627-641
Cell death and differentiation 2022 Mar;29(3):627-641
DECR1 directly activates HSL to promote lipolysis in cervical cancer cells.
Zhou H, Zhang J, Yan Z, Qu M, Zhang G, Han J, Wang F, Sun K, Wang L, Yang X
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Mar;1867(3):159090
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Mar;1867(3):159090
A novel mechanism of the lncRNA PTTG3P/miR-142-5p/JAG1 axis modulating tongue cancer cell phenotypes through the Notch1 signaling.
Zhang T, Liu X, Su K, Zheng Q, Liu P, Xu Z, Zhang Y
Cells & development 2022 Mar;169:203762
Cells & development 2022 Mar;169:203762
Bisphenol A drives di(2-ethylhexyl) phthalate promoting thyroid tumorigenesis via regulating HDAC6/PTEN and c-MYC signaling.
Zhang X, Guo N, Jin H, Liu R, Zhang Z, Cheng C, Fan Z, Zhang G, Xiao M, Wu S, Zhao Y, Lu X
Journal of hazardous materials 2022 Mar 5;425:127911
Journal of hazardous materials 2022 Mar 5;425:127911
Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma Cells.
Arena A, Romeo MA, Benedetti R, Gilardini Montani MS, Cirone M
Biomedicines 2022 Mar 22;10(4)
Biomedicines 2022 Mar 22;10(4)
SP2509, a Selective Inhibitor of LSD1, Suppresses Retinoblastoma Growth by Downregulating β-catenin Signaling.
Jiang A, Wu W, Xu C, Mao L, Ao S, Guo H, Sun X, Tao J, Sang Y, Huang G
Investigative ophthalmology & visual science 2022 Mar 2;63(3):20
Investigative ophthalmology & visual science 2022 Mar 2;63(3):20
Inhibition of STAT3(Y705) phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells.
Guo H, Xiao Y, Yuan Z, Yang X, Chen J, Chen C, Wang M, Xie L, Chen Q, Tong Y, Zhang Q, Bai Y
Cell death discovery 2022 Mar 14;8(1):116
Cell death discovery 2022 Mar 14;8(1):116
CircTCF25 serves as a sponge for miR-206 to support proliferation, migration, and invasion of glioma via the Jak2/p-Stat3/CypB axis.
Yin H, Wang H, Wang M, Yan Y, Dong Q, Li Q, Liu Y, Wang X, Guo T, Niu L, Zhang H, Wang B, Yao X, Yuan G, Pan Y
Molecular carcinogenesis 2022 Jun;61(6):558-571
Molecular carcinogenesis 2022 Jun;61(6):558-571
c-MYC and HIF1α promoter G-quadruplexes dependent metabolic regulation mechanism of berberine in colon cancer.
Wen L, Han Z, Li J, Du Y
Journal of gastrointestinal oncology 2022 Jun;13(3):1152-1168
Journal of gastrointestinal oncology 2022 Jun;13(3):1152-1168
N-methyl-D-aspartate receptor blockers attenuate bleomycin-induced pulmonary fibrosis by inhibiting endogenous mesenchymal stem cells senescence.
Huang P, Zhou Y, Li XH, Zhang YN, Cheng HP, Fu JF, Liu W, Yue S, Luo ZQ
Annals of translational medicine 2022 Jun;10(11):642
Annals of translational medicine 2022 Jun;10(11):642
Paired box 8 facilitates the c-MYC related cell cycle progress in TP53-mutation uterine corpus endometrial carcinoma through interaction with DDX5.
Qiu P, Jie Y, Ma C, Chen H, Qin Y, Tu K, Wang L, Zhang Z
Cell death discovery 2022 Jun 7;8(1):276
Cell death discovery 2022 Jun 7;8(1):276
Synthesis and structure-activity relationship study of a potent MHO7 analogue as potential anti-triple negative breast cancer agent.
Liang JJ, Yu WL, Yang L, Qin KM, Yin YP, Li D, Ni YH, Yan JJ, Zhong YX, Deng ZX, Hong K
European journal of medicinal chemistry 2022 Jun 5;236:114313
European journal of medicinal chemistry 2022 Jun 5;236:114313
Metformin abrogates pathological TNF-α-producing B cells through mTOR-dependent metabolic reprogramming in polycystic ovary syndrome.
Xiao N, Wang J, Wang T, Xiong X, Zhou J, Su X, Peng J, Yang C, Li X, Lin G, Lu G, Gong F, Cheng L
eLife 2022 Jun 24;11
eLife 2022 Jun 24;11
TET2-BCLAF1 transcription repression complex epigenetically regulates the expression of colorectal cancer gene Ascl2 via methylation of its promoter.
Shang Y, Jiang T, Ran L, Hu W, Wu Y, Ye J, Peng Z, Chen L, Wang R
The Journal of biological chemistry 2022 Jul;298(7):102095
The Journal of biological chemistry 2022 Jul;298(7):102095
Photoaffinity Labeling-Based Chemoproteomic Strategy Reveals RBBP4 as a Cellular Target of Protopanaxadiol against Colorectal Cancer Cells.
Zhuo FF, Guo Q, Zheng YZ, Liu TT, Yang Z, Xu QH, Jiang Y, Liu D, Zeng KW, Tu PF
Chembiochem : a European journal of chemical biology 2022 Jul 5;23(13):e202200038
Chembiochem : a European journal of chemical biology 2022 Jul 5;23(13):e202200038
miR-3682-3p directly targets FOXO3 and stimulates tumor stemness in hepatocellular carcinoma via a positive feedback loop involving FOXO3/PI3K/AKT/c-Myc.
Chen Q, Yang SB, Zhang YW, Han SY, Jia L, Li B, Zhang Y, Zuo S
World journal of stem cells 2022 Jul 26;14(7):539-555
World journal of stem cells 2022 Jul 26;14(7):539-555
Ginsenoside Rh4 Suppresses Metastasis of Esophageal Cancer and Expression of c-Myc via Targeting the Wnt/β-Catenin Signaling Pathway.
Chen J, Duan Z, Liu Y, Fu R, Zhu C
Nutrients 2022 Jul 25;14(15)
Nutrients 2022 Jul 25;14(15)
CTNND1 variants cause familial exudative vitreoretinopathy through the Wnt/cadherin axis.
Yang M, Li S, Huang L, Zhao R, Dai E, Jiang X, He Y, Lu J, Peng L, Liu W, Zhang Z, Jiang D, Zhang Y, Jiang Z, Yang Y, Zhao P, Zhu X, Ding X, Yang Z
JCI insight 2022 Jul 22;7(14)
JCI insight 2022 Jul 22;7(14)
Forkhead Box S1 mediates epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway to regulate colorectal cancer progression.
Zhang L, Ren CF, Yang Z, Gong LB, Wang C, Feng M, Guan WX
Journal of translational medicine 2022 Jul 21;20(1):327
Journal of translational medicine 2022 Jul 21;20(1):327
c-myc-mediated upregulation of NAT10 facilitates tumor development via cell cycle regulation in non-small cell lung cancer.
Wang Z, Huang Y, Lu W, Liu J, Li X, Zhu S, Liu H, Song Y
Medical oncology (Northwood, London, England) 2022 Jul 14;39(10):140
Medical oncology (Northwood, London, England) 2022 Jul 14;39(10):140
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells.
Arena A, Romeo MA, Benedetti R, Gilardini Montani MS, Cirone M
Biochemical and biophysical research communications 2022 Jul 12;613:19-25
Biochemical and biophysical research communications 2022 Jul 12;613:19-25
DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and Kaposi sarcoma herpesvirus replication.
Arena A, Gilardini Montani MS, Romeo MA, Benedetti R, Gaeta A, Cirone M
Biochimica et biophysica acta. Molecular cell research 2022 Jan;1869(1):119168
Biochimica et biophysica acta. Molecular cell research 2022 Jan;1869(1):119168
Luteolin alleviates ischemia/reperfusion injury-induced no-reflow by regulating Wnt/β-catenin signaling in rats.
Qin X, Qin H, Li Z, Xue S, Huang B, Liu X, Wang D
Microvascular research 2022 Jan;139:104266
Microvascular research 2022 Jan;139:104266
c-Myc Targets HDAC3 to Suppress NKG2DL Expression and Innate Immune Response in N-Type SCLC through Histone Deacetylation.
Zhao P, Sun X, Li H, Liu Y, Cui Y, Tian L, Cheng Y
Cancers 2022 Jan 18;14(3)
Cancers 2022 Jan 18;14(3)
Integrating network pharmacology deciphers the action mechanism of Zuojin capsule in suppressing colorectal cancer.
Fan JH, Xu MM, Zhou LM, Gui ZW, Huang L, Li XG, Ye XL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153881
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153881
Estrogen receptor beta increases clear cell renal cell carcinoma stem cell phenotype via altering the circPHACTR4/miR-34b-5p/c-Myc signaling.
Wang Y, Yang Z, Gu J, Zhang Y, Wang X, Teng Z, Wang D, Gao L, Li W, Yeh S, Han Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22163
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22163
CDK14/β-catenin/TCF4/miR-26b positive feedback regulation modulating pancreatic cancer cell phenotypes in vitro and tumor growth in mice model in vivo.
Sun Y, Wang P, Zhang Q, Wu H
The journal of gene medicine 2022 Feb;24(2):e3343
The journal of gene medicine 2022 Feb;24(2):e3343
l-Argine regulates the proliferation, apoptosis and endocrine activity by alleviating oxidative stress in sheep endometrial epithelial cells.
Gao X, Li X, Wang Z, Li K, Liang Y, Yao X, Zhang G, Wang F
Theriogenology 2022 Feb;179:187-196
Theriogenology 2022 Feb;179:187-196
Myocardin/microRNA-30a/Beclin1 signaling controls the phenotypic modulation of vascular smooth muscle cells by regulating autophagy.
Shi D, Ding J, Xie S, Huang L, Zhang H, Chen X, Ren X, Zhou S, He H, Ma W, Zhang T, Wang N
Cell death & disease 2022 Feb 8;13(2):121
Cell death & disease 2022 Feb 8;13(2):121
The miR-34a/WNT7B modulates the sensitivity of cholangiocarcinoma cells to p53-mediated photodynamic therapy toxicity.
Han Y, Yang Y, Huang S, Yao L, Wu L
Biochemical and biophysical research communications 2022 Feb 5;591:54-61
Biochemical and biophysical research communications 2022 Feb 5;591:54-61
The anti-MDR efficacy of YAN against A549/Taxol cells is associated with its inhibition on glycolysis and is further enhanced by 2-deoxy-d-glucose.
Gao M, Yang Y, Gao Y, Liu T, Guan Q, Zhou T, Shi Y, Hao M, Li Z, Zuo D, Zhang W, Wu Y
Chemico-biological interactions 2022 Feb 25;354:109843
Chemico-biological interactions 2022 Feb 25;354:109843
Circular RNA circSHPRH inhibits the malignant behaviors of bladder cancer by regulating the miR-942/BARX2 pathway.
Zuo L, Zhu Y, Han J, Liu H
Aging 2022 Feb 24;14(4):1891-1909
Aging 2022 Feb 24;14(4):1891-1909
Programmed death-ligand 1 signaling and expression are reversible by lycopene via PI3K/AKT and Raf/MEK/ERK pathways in tongue squamous cell carcinoma.
Peng M, Fan S, Li J, Zhou X, Liao Q, Tang F, Liu W
Genes & nutrition 2022 Feb 14;17(1):3
Genes & nutrition 2022 Feb 14;17(1):3
Blockade of Nuclear β-Catenin Signaling via Direct Targeting of RanBP3 with NU2058 Induces Cell Senescence to Suppress Colorectal Tumorigenesis.
Zheng CC, Liao L, Liu YP, Yang YM, He Y, Zhang GG, Li SJ, Liu T, Xu WW, Li B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Dec;9(34):e2202528
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Dec;9(34):e2202528
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Bian Y, Xue M, Guo X, Jiang W, Zhao Y, Zhang Z, Wang X, Hu Y, Zhang Q, Dun W, Zhang L
Pharmaceutical biology 2022 Dec;60(1):1801-1811
Pharmaceutical biology 2022 Dec;60(1):1801-1811
Long non-coding RNA CTSLP8 mediates ovarian cancer progression and chemotherapy resistance by modulating cellular glycolysis and regulating c-Myc expression through PKM2.
Li X, Zhang Y, Wang X, Lin F, Cheng X, Wang Z, Wang X
Cell biology and toxicology 2022 Dec;38(6):1027-1045
Cell biology and toxicology 2022 Dec;38(6):1027-1045
Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity.
Jin X, Li X, Li L, Zhong B, Hong Y, Niu J, Li B
The Journal of biological chemistry 2022 Dec;298(12):102587
The Journal of biological chemistry 2022 Dec;298(12):102587
CircP50 functions through the phosphorylation- and acetylation-activated p53 pathway to mediate inorganic arsenic-induced apoptosis in A549 cells.
Mao Y, Zhou Q, Wang J, Zhao R, Yang X, Shi Y, Yin J, Jiang C, He Y
Environmental science and pollution research international 2022 Dec;29(60):91232-91240
Environmental science and pollution research international 2022 Dec;29(60):91232-91240
Low expression of MYCN promotes cisplatin resistance by suppressing cisplatin-induced apoptosis in epithelial ovarian cancer.
Yu R, Zhang H, Wang R, Xiao L
Oncology letters 2022 Dec;24(6):423
Oncology letters 2022 Dec;24(6):423
USF1-CHCHD4 axis promotes lung adenocarcinoma progression partially via activating the MYC pathway.
Zhou Y, Zhao Y, Ma W, Zhang L, Jiang Y, Dong W
Discover oncology 2022 Dec 8;13(1):136
Discover oncology 2022 Dec 8;13(1):136
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Wu X, Zhang H, Jiang G, Peng M, Li C, Lu J, Jiang S, Yang X, Jiang Y
Clinical and experimental immunology 2022 Dec 31;210(3):309-320
Clinical and experimental immunology 2022 Dec 31;210(3):309-320
SMAD4 Loss Induces c-MYC-Mediated NLE1 Upregulation to Support Protein Biosynthesis, Colorectal Cancer Growth, and Metastasis.
Loevenich LP, Tschurtschenthaler M, Rokavec M, Silva MG, Jesinghaus M, Kirchner T, Klauschen F, Saur D, Neumann J, Hermeking H, Jung P
Cancer research 2022 Dec 16;82(24):4604-4623
Cancer research 2022 Dec 16;82(24):4604-4623
Unraveling the toxic effects mediated by the neurodegenerative disease-associated S375G mutation of TDP-43 and its S375E phosphomimetic variant.
Paron F, Barattucci S, Cappelli S, Romano M, Berlingieri C, Stuani C, Laurents D, Mompeán M, Buratti E
The Journal of biological chemistry 2022 Aug;298(8):102252
The Journal of biological chemistry 2022 Aug;298(8):102252
NSUN2-mediated RNA m(5)C modification modulates uveal melanoma cell proliferation and migration.
Luo G, Xu W, Chen X, Wang S, Wang J, Dong F, Hu DN, Reinach PS, Yan D
Epigenetics 2022 Aug;17(8):922-933
Epigenetics 2022 Aug;17(8):922-933
Phosphorylated STYK1 restrains the inhibitory role of EGFR in autophagy initiation and EGFR-TKIs sensitivity.
Zhou C, Dong X, Wang M, Qian X, Hu M, Liang K, Liang Y, Zhang R, Huang Y, Lyu H, Xiao S, Tang Y, Ali DW, Michalak M, Chen XZ, Tang J
Cell insight 2022 Aug;1(4):100045
Cell insight 2022 Aug;1(4):100045
Molecular cloning, characterization, and tissue distribution of c-Myc from blood clam Tegillarca granosa and its role in cadmium-induced stress response.
Zhao D, Hu G, Chen R, Xiao G, Teng S
Gene 2022 Aug 5;834:146611
Gene 2022 Aug 5;834:146611
Alpha-linolenic acid inhibits hepatocellular carcinoma cell growth through Farnesoid X receptor/β-catenin signaling pathway.
Feng S, Xie X, Chen C, Zuo S, Zhao X, Li H
Nutrition & metabolism 2022 Aug 23;19(1):57
Nutrition & metabolism 2022 Aug 23;19(1):57
Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas.
Benedetti R, Arena A, Romeo MA, Gilardini Montani MS, Gonnella R, Santarelli R, Trivedi P, Cirone M
International journal of molecular sciences 2022 Aug 14;23(16)
International journal of molecular sciences 2022 Aug 14;23(16)
c-Abl kinase-mediated phosphorylation of γ-tubulin promotes γ-tubulin ring complexes assembly and microtubule nucleation.
Wang GF, Dong Q, Bai Y, Gu J, Tao Q, Yue J, Zhou R, Niu X, Zhu L, Song C, Zheng T, Wang D, Jin Y, Liu H, Cao C, Liu X
The Journal of biological chemistry 2022 Apr;298(4):101778
The Journal of biological chemistry 2022 Apr;298(4):101778
USP19 (ubiquitin specific peptidase 19) promotes TBK1 (TANK-binding kinase 1) degradation via chaperone-mediated autophagy.
Zhao X, Di Q, Yu J, Quan J, Xiao Y, Zhu H, Li H, Ling J, Chen W
Autophagy 2022 Apr;18(4):891-908
Autophagy 2022 Apr;18(4):891-908
HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC.
Zhang G, Zhu Q, Yan X, Ci M, Zhao E, Hou J, Wan S, Lü M, Cui H
Cell death discovery 2022 Apr 9;8(1):185
Cell death discovery 2022 Apr 9;8(1):185
Mitochondrial fragmentation is crucial for c-Myc-driven hepatoblastoma-like liver tumors.
Wang D, Tian J, Yan Z, Yuan Q, Wu D, Liu X, Yang S, Guo S, Wang J, Yang Y, Xing J, An J, Huang Q
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Apr 6;30(4):1645-1660
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Apr 6;30(4):1645-1660
RNF8 up-regulates AR/ARV7 action to contribute to advanced prostate cancer progression.
Zhou T, Wang S, Song X, Liu W, Dong F, Huo Y, Zou R, Wang C, Zhang S, Liu W, Sun G, Lin L, Zeng K, Dong X, Guo Q, Yi F, Wang Z, Li X, Jiang B, Cao L, Zhao Y
Cell death & disease 2022 Apr 15;13(4):352
Cell death & disease 2022 Apr 15;13(4):352
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
Jin C, Ou Q, Chen J, Wang T, Zhang J, Wang Z, Wang Y, Tian H, Xu JY, Gao F, Wang J, Li J, Lu L, Xu GT
Stem cell research & therapy 2022 Apr 1;13(1):136
Stem cell research & therapy 2022 Apr 1;13(1):136
Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction.
Zhang J, Yang P, Liu D, Gao M, Wang J, Yu T, Zhang X, Liu Y
Burns & trauma 2021;9:tkab031
Burns & trauma 2021;9:tkab031
IL-18-Mediated SLC7A5 Overexpression Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells via the c-MYC Pathway.
Ni F, Zhang T, Xiao W, Dong H, Gao J, Liu Y, Li J
Frontiers in cell and developmental biology 2021;9:748831
Frontiers in cell and developmental biology 2021;9:748831
CircGNG4 Promotes the Progression of Prostate Cancer by Sponging miR-223 to Enhance EYA3/c-myc Expression.
Xu S, Lian Z, Zhang S, Xu Y, Zhang H
Frontiers in cell and developmental biology 2021;9:684125
Frontiers in cell and developmental biology 2021;9:684125
SP1-Mediated Upregulation of Long Noncoding RNA ZFAS1 Involved in Non-syndromic Cleft Lip and Palate via Inactivating WNT/β-Catenin Signaling Pathway.
Chen S, Jia Z, Cai M, Ye M, Wu D, Wan T, Zhang B, Wu P, Xu Y, Guo Y, Tian C, Ma D, Ma J
Frontiers in cell and developmental biology 2021;9:662780
Frontiers in cell and developmental biology 2021;9:662780
Blockage of Extracellular Signal-Regulated Kinase Exerts an Antitumor Effect via Regulating Energy Metabolism and Enhances the Efficacy of Autophagy Inhibitors by Regulating Transcription Factor EB Nuclear Translocation in Osteosarcoma.
Zhang M, Bai Y, Xu C, Qi Y, Meng J, Zhang W, Su H, Yan W
Frontiers in cell and developmental biology 2021;9:650846
Frontiers in cell and developmental biology 2021;9:650846
CORO6 Promotes Cell Growth and Invasion of Clear Cell Renal Cell Carcinoma via Activation of WNT Signaling.
Wang X, Xiao Y, Li S, Yan Z, Luo G
Frontiers in cell and developmental biology 2021;9:647301
Frontiers in cell and developmental biology 2021;9:647301
Kochia scoparia Saponin Momordin Ic Modulates HaCaT Cell Proliferation and Apoptosis via the Wnt/β-Catenin Pathway.
Luo M, Zeng B, Wang H, Yang Z, Peng Y, Zhang Y, Wang C
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5522164
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5522164
Effects of MicroRNA-195-5p on Biological Behaviors and Radiosensitivity of Lung Adenocarcinoma Cells via Targeting HOXA10.
Yuan C, Bai R, Gao Y, Jiang X, Li S, Sun W, Li Y, Huang Z, Gong Y, Xie C
Oxidative medicine and cellular longevity 2021;2021:4522210
Oxidative medicine and cellular longevity 2021;2021:4522210
NEK2 plays an active role in Tumorigenesis and Tumor Microenvironment in Non-Small Cell Lung Cancer.
Bai R, Yuan C, Sun W, Zhang J, Luo Y, Gao Y, Li Y, Gong Y, Xie C
International journal of biological sciences 2021;17(8):1995-2008
International journal of biological sciences 2021;17(8):1995-2008
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.
Bai M, Cui M, Li M, Yao X, Wu Y, Zheng L, Sun L, Song Q, Wang S, Liu L, Yu C, Huang Y
International journal of biological sciences 2021;17(13):3493-3507
International journal of biological sciences 2021;17(13):3493-3507
TRIM11 Promotes Proliferation, Migration, Invasion and EMT of Gastric Cancer by Activating β-Catenin Signaling.
Lan Q, Tan X, He P, Li W, Tian S, Dong W
OncoTargets and therapy 2021;14:1429-1440
OncoTargets and therapy 2021;14:1429-1440
Novel lncRNA LINC01614 Facilitates Bladder Cancer Proliferation, Migration and Invasion Through the miR-217/RUNX2/Wnt/β-Catenin Axis.
Wang Z, Yan H, Cheng D, Xu L, Shen T, Chen Y, Han R, Xue Y
Cancer management and research 2021;13:8387-8397
Cancer management and research 2021;13:8387-8397
Coronin 6 promotes hepatocellular carcinoma progression by enhancing canonical Wnt/beta-catenin signaling pathway.
Zhang J, Li P, Li T, Zhou Z, Wu H, Zhang L
Journal of Cancer 2021;12(24):7465-7476
Journal of Cancer 2021;12(24):7465-7476
LncRNA MALAT1 was regulated by HPV16 E7 independently of pRB in cervical cancer cells.
Wang T, Zhang W, Huang W, Hua Z, Li S
Journal of Cancer 2021;12(21):6344-6355
Journal of Cancer 2021;12(21):6344-6355
c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.
Zhang J, Yang P, Liu D, Gao M, Wang J, Wang X, Liu Y, Zhang X
Frontiers in endocrinology 2021;12:676403
Frontiers in endocrinology 2021;12:676403
SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.
Sui L, Zhao Y, Wang W, Wu P, Wang Z, Yu Y, Hou Z, Tan G, Liu Q
Frontiers in immunology 2021;12:662989
Frontiers in immunology 2021;12:662989
Therapeutic Potential of CUDC-907 (Fimepinostat) for Hepatocarcinoma Treatment Revealed by Tumor Spheroids-Based Drug Screening.
Liao W, Yang W, Xu J, Yan Z, Pan M, Xu X, Zhou S, Zhu Y, Lan J, Zeng M, Han X, Li S, Li Y, Liang K, Gao Y, Peng Q
Frontiers in pharmacology 2021;12:658197
Frontiers in pharmacology 2021;12:658197
YY1-mediated reticulocalbin-2 upregulation promotes the hepatocellular carcinoma progression via activating MYC signaling.
Mei C, Jiang X, Gu Y, Wu X, Ma W, Chen X, Wang G, Yao Y, Liu Y, Zhang Z, Yuan Y
American journal of cancer research 2021;11(5):2238-2251
American journal of cancer research 2021;11(5):2238-2251
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Liu W, Zhan Z, Zhang M, Sun B, Shi Q, Luo F, Zhang M, Zhang W, Hou Y, Xiao X, Li Y, Feng H
Theranostics 2021;11(13):6278-6292
Theranostics 2021;11(13):6278-6292
tRNA-Derived Fragment tRF-Glu-TTC-027 Regulates the Progression of Gastric Carcinoma via MAPK Signaling Pathway.
Xu W, Zhou B, Wang J, Tang L, Hu Q, Wang J, Chen H, Zheng J, Yan F, Chen H
Frontiers in oncology 2021;11:733763
Frontiers in oncology 2021;11:733763
Oleic Acid and Insulin as Key Characteristics of T2D Promote Colorectal Cancer Deterioration in Xenograft Mice Revealed by Functional Metabolomics.
Zhang Y, Wang D, Lv B, Hou X, Liu Q, Liao C, Xu R, Zhang Y, Xu F, Zhang P
Frontiers in oncology 2021;11:685059
Frontiers in oncology 2021;11:685059
A Novel Mechanism of the c-Myc/NEAT1 Axis Mediating Colorectal Cancer Cell Response to Photodynamic Therapy Treatment.
Liu K, Lei S, Kuang Y, Jin Q, Long D, Liu C, Jiang Y, Zhao H, Yao H
Frontiers in oncology 2021;11:652831
Frontiers in oncology 2021;11:652831
MiR-338-5p Inhibits EGF-Induced EMT in Pancreatic Cancer Cells by Targeting EGFR/ERK Signaling.
Sun J, Chen L, Dong M
Frontiers in oncology 2021;11:616481
Frontiers in oncology 2021;11:616481
Paired-like homeodomain transcription factor 2 affects endometrial cell function and embryo implantation through the Wnt/β-catenin pathway.
Zhang H, Qi J, Guo J, Wang Y, Guan Y, Fan J, Sui L, Xu Y, Kong L, Yan B, Kong Y
Cell biology international 2021 Sep;45(9):1957-1965
Cell biology international 2021 Sep;45(9):1957-1965
Expression of TCF3 in Wilms' tumor and its regulatory role in kidney tumor cell viability, migration and apoptosis in vitro.
Zhou N, Yan B, Ma J, Jiang H, Li L, Tang H, Ji F, Yao Z
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
Zeng S, Chen L, Sun Q, Zhao H, Yang H, Ren S, Liu M, Meng X, Xu H
European journal of pharmacology 2021 Sep 5;906:174253
European journal of pharmacology 2021 Sep 5;906:174253
PHLDA3 exerts an antitumor function in prostate cancer by down-regulating Wnt/β-catenin pathway via inhibition of Akt.
Ma S, Quan P, Yu C, Fan X, Yang S, Jia W, Zhang L, Wang F, Liu F, Yang L, Qin W, Yang X
Biochemical and biophysical research communications 2021 Sep 24;571:66-73
Biochemical and biophysical research communications 2021 Sep 24;571:66-73
Bromodomain-containing protein 9 promotes hepatocellular carcinoma progression via activating the Wnt/β-catenin signaling pathway.
Fang D, Wang MR, Guan JL, Han YY, Sheng JQ, Tian DA, Li PY
Experimental cell research 2021 Sep 15;406(2):112727
Experimental cell research 2021 Sep 15;406(2):112727
Co-exposure to BPA and DEHP enhances susceptibility of mammary tumors via up-regulating Esr1/HDAC6 pathway in female rats.
Zhang X, Cheng C, Zhang G, Xiao M, Li L, Wu S, Lu X
Ecotoxicology and environmental safety 2021 Sep 15;221:112453
Ecotoxicology and environmental safety 2021 Sep 15;221:112453
Clusterin inhibits Cr(VI)-induced apoptosis via enhancing mitochondrial biogenesis through AKT-associated STAT3 activation in L02 hepatocytes.
Liang N, Li S, Liang Y, Ma Y, Tang S, Ye S, Xiao F
Ecotoxicology and environmental safety 2021 Sep 15;221:112447
Ecotoxicology and environmental safety 2021 Sep 15;221:112447
LPCAT1 reprogramming cholesterol metabolism promotes the progression of esophageal squamous cell carcinoma.
Tao M, Luo J, Gu T, Yu X, Song Z, Jun Y, Gu H, Han K, Huang X, Yu W, Sun S, Zhang Z, Liu L, Chen X, Zhang L, Luo C, Wang Q
Cell death & disease 2021 Sep 13;12(9):845
Cell death & disease 2021 Sep 13;12(9):845
LGR6 activates the Wnt/β-catenin signaling pathway and forms a β-catenin/TCF7L2/LGR6 feedback loop in LGR6(high) cervical cancer stem cells.
Feng Q, Li S, Ma HM, Yang WT, Zheng PS
Oncogene 2021 Oct;40(42):6103-6114
Oncogene 2021 Oct;40(42):6103-6114
ASPM promotes hepatocellular carcinoma progression by activating Wnt/β-catenin signaling through antagonizing autophagy-mediated Dvl2 degradation.
Zhang H, Yang X, Zhu L, Li Z, Zuo P, Wang P, Feng J, Mi Y, Zhang C, Xu Y, Jin G, Zhang J, Ye H
FEBS open bio 2021 Oct;11(10):2784-2799
FEBS open bio 2021 Oct;11(10):2784-2799
The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation.
Li Y, Zhang N, Ma C, Xu W, Jin G, Zheng Y, Zhang L, Liu B, Gao C, Liu S
Cell death & disease 2021 Oct 26;12(11):1001
Cell death & disease 2021 Oct 26;12(11):1001
Cancer cell immune mimicry delineates onco-immunologic modulation.
Gao R, He B, Huang Q, Wang Z, Yan M, Lam EW, Lin S, Wang B, Liu Q
iScience 2021 Oct 22;24(10):103133
iScience 2021 Oct 22;24(10):103133
RCN1 induces sorafenib resistance and malignancy in hepatocellular carcinoma by activating c-MYC signaling via the IRE1α-XBP1s pathway.
Wang JW, Ma L, Liang Y, Yang XJ, Wei S, Peng H, Qiu SP, Lu X, Zhu YQ, Wang BL
Cell death discovery 2021 Oct 18;7(1):298
Cell death discovery 2021 Oct 18;7(1):298
An SETD1A/Wnt/β-catenin feedback loop promotes NSCLC development.
Wang R, Liu J, Li K, Yang G, Chen S, Wu J, Xie X, Ren H, Pang Y
Journal of experimental & clinical cancer research : CR 2021 Oct 13;40(1):318
Journal of experimental & clinical cancer research : CR 2021 Oct 13;40(1):318
GRIM-19 inhibits proliferation and induces apoptosis in a p53-dependent manner in colorectal cancer cells through the SIRT7/PCAF/MDM2 axis.
Wang D, Wei X, Chen X, Wang Q, Zhang J, Kalvakolanu DV, Guo B, Zhang L
Experimental cell research 2021 Oct 1;407(1):112799
Experimental cell research 2021 Oct 1;407(1):112799
The ER membrane protein complex subunit Emc3 controls angiogenesis via the FZD4/WNT signaling axis.
Yang M, Li S, Liu W, Li X, He Y, Yang Y, Sun K, Zhang L, Tian W, Duan L, Chen H, Yao D, Yang Z, Zhu X
Science China. Life sciences 2021 Nov;64(11):1868-1883
Science China. Life sciences 2021 Nov;64(11):1868-1883
Babao Dan is a robust anti-tumor agent via inhibiting wnt/β-catenin activation and cancer cell stemness.
Xie X, Chen J, Wo D, Ma E, Ning Y, Peng J, Zhu W, Ren DN
Journal of ethnopharmacology 2021 Nov 15;280:114449
Journal of ethnopharmacology 2021 Nov 15;280:114449
The parent-of-origin lncRNA MISSEN regulates rice endosperm development.
Zhou YF, Zhang YC, Sun YM, Yu Y, Lei MQ, Yang YW, Lian JP, Feng YZ, Zhang Z, Yang L, He RR, Huang JH, Cheng Y, Liu YW, Chen YQ
Nature communications 2021 Nov 11;12(1):6525
Nature communications 2021 Nov 11;12(1):6525
Model-based analysis uncovers mutations altering autophagy selectivity in human cancer.
Han Z, Zhang W, Ning W, Wang C, Deng W, Li Z, Shang Z, Shen X, Liu X, Baba O, Morita T, Chen L, Xue Y, Jia D
Nature communications 2021 May 31;12(1):3258
Nature communications 2021 May 31;12(1):3258
ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling.
Zhu T, Zheng J, Zhuo W, Pan P, Li M, Zhang W, Zhou H, Gao Y, Li X, Liu Z
Cell death discovery 2021 May 29;7(1):126
Cell death discovery 2021 May 29;7(1):126
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
Zhang J, Ma X, Fan D
Foods (Basel, Switzerland) 2021 May 26;10(6)
Foods (Basel, Switzerland) 2021 May 26;10(6)
Apatinib suppresses lung cancer stem-like cells by complex interplay between β-catenin signaling and mitochondrial ROS accumulation.
Zhu J, Li X, Liang C, Zhou X, Ge M, Chen Y, Jin J, Yin J, Xu H, Xie C, Zhong C
Cell death discovery 2021 May 12;7(1):102
Cell death discovery 2021 May 12;7(1):102
SHARPIN stabilizes β-catenin through a linear ubiquitination-independent manner to support gastric tumorigenesis.
Zhang L, Liu Q, Liu KW, Qin ZY, Zhu GX, Shen LT, Zhang N, Liu BY, Che LR, Li JY, Wang T, Wen LZ, Liu KJ, Guo Y, Yin XR, Wang XW, Zhou ZH, Xiao HL, Cui YH, Bian XW, Lan CH, Chen D, Wang B
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2021 Mar;24(2):402-416
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2021 Mar;24(2):402-416
LncRNA NBR2 aggravates hepatoblastoma cell malignancy and promotes cell proliferation under glucose starvation through the miR-22/TCF7 axis.
Zhu C, He X, Chen K, Huang Z, Yao A, Tian X, You Y, Zeng M
Cell cycle (Georgetown, Tex.) 2021 Mar-Mar;20(5-6):575-590
Cell cycle (Georgetown, Tex.) 2021 Mar-Mar;20(5-6):575-590
The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation.
Shang M, Yang H, Yang R, Chen T, Fu Y, Li Y, Fang X, Zhang K, Zhang J, Li H, Cao X, Gu J, Xiao J, Zhang Q, Liu X, Yu Q, Wang T
Nature communications 2021 Mar 29;12(1):1940
Nature communications 2021 Mar 29;12(1):1940
FAM122A promotes acute myeloid leukemia cell growth through inhibiting PP2A activity and sustaining MYC expression.
Liu MH, Chen J, Yang YS, Wang YQ, Chen GQ, Zhang Y, Huang Y
Haematologica 2021 Mar 1;106(3):903-907
Haematologica 2021 Mar 1;106(3):903-907
Salidroside overcomes dexamethasone resistance in T-acute lymphoblastic leukemia cells.
Niu YN, Zeng Y, Zhong FF, Long SL, Ren DW, Qin X, Liu WJ
Experimental and therapeutic medicine 2021 Jun;21(6):636
Experimental and therapeutic medicine 2021 Jun;21(6):636
Exosomal SNHG16 secreted by CSCs promotes glioma development via TLR7.
Zhang R, Li P, Lv H, Li N, Ren S, Xu W
Stem cell research & therapy 2021 Jun 16;12(1):349
Stem cell research & therapy 2021 Jun 16;12(1):349
The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC.
Wang X, Xing L, Yang R, Chen H, Wang M, Jiang R, Zhang L, Chen J
Molecular cancer 2021 Jun 11;20(1):91
Molecular cancer 2021 Jun 11;20(1):91
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
Zhang L, Cao H, Tao H, Yang J, Gong W, Hu Q
Experimental and therapeutic medicine 2021 Jul;22(1):696
Experimental and therapeutic medicine 2021 Jul;22(1):696
MMP12 is a potential therapeutic target for Adamantinomatous craniopharyngioma: Conclusions from bioinformatics analysis and in vitro experiments.
Li M, Zhou L, Li S, Fang L, Yang L, Wu X, Yang C, Bao Y, Lan S, Tong Z, Zheng S, Tang B, Zeng E, Xie S, Chen C, Hong T
Oncology letters 2021 Jul;22(1):536
Oncology letters 2021 Jul;22(1):536
WRKY9 transcription factor regulates cytochrome P450 genes CYP94B3 and CYP86B1, leading to increased root suberin and salt tolerance in Arabidopsis.
Krishnamurthy P, Vishal B, Bhal A, Kumar PP
Physiologia plantarum 2021 Jul;172(3):1673-1687
Physiologia plantarum 2021 Jul;172(3):1673-1687
A Novel Long Non-Coding RNA lnc030 Maintains Breast Cancer Stem Cell Stemness by Stabilizing SQLE mRNA and Increasing Cholesterol Synthesis.
Qin Y, Hou Y, Liu S, Zhu P, Wan X, Zhao M, Peng M, Zeng H, Li Q, Jin T, Cui X, Liu M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jan;8(2):2002232
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jan;8(2):2002232
miR-937-5p targets SOX17 to modulate breast cancer cell cycle and cell proliferation through the Wnt signaling pathway.
Xiong X, Xu W, Gong J, Wang L, Dai M, Chen G, Yuan L
Cellular signalling 2021 Jan;77:109818
Cellular signalling 2021 Jan;77:109818
Mutant TP53 interacts with BCAR1 to contribute to cancer cell invasion.
Guo AK, Itahana Y, Seshachalam VP, Chow HY, Ghosh S, Itahana K
British journal of cancer 2021 Jan;124(1):299-312
British journal of cancer 2021 Jan;124(1):299-312
TRIP13 promotes the proliferation and invasion of lung cancer cells via the Wnt signaling pathway and epithelial-mesenchymal transition.
Li ZH, Lei L, Fei LR, Huang WJ, Zheng YW, Yang MQ, Wang Z, Liu CC, Xu HT
Journal of molecular histology 2021 Feb;52(1):11-20
Journal of molecular histology 2021 Feb;52(1):11-20
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
Liu S, Gong Y, Xu XD, Shen H, Gao S, Bao HD, Guo SB, Yu XF, Gong J
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
The effects of histone crotonylation and bromodomain protein 4 on prostate cancer cell lines.
Xu X, Zhu X, Liu F, Lu W, Wang Y, Yu J
Translational andrology and urology 2021 Feb;10(2):900-914
Translational andrology and urology 2021 Feb;10(2):900-914
Cholesterol activates the Wnt/PCP-YAP signaling in SOAT1-targeted treatment of colon cancer.
Xu H, Xia H, Zhou S, Tang Q, Bi F
Cell death discovery 2021 Feb 26;7(1):38
Cell death discovery 2021 Feb 26;7(1):38
OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase.
Kim HJ, Kim J
International journal of molecular sciences 2021 Feb 16;22(4)
International journal of molecular sciences 2021 Feb 16;22(4)
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
Liu S, Chen L, Chen H, Xu K, Peng X, Zhang M
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66
MEG3/MIR-376B-3P/HMGA2 axis is involved in pituitary tumor invasiveness.
Zhu D, Xiao Z, Wang Z, Hu B, Duan C, Zhu Z, Gao N, Zhu Y, Wang H
Journal of neurosurgery 2021 Feb 1;134(2):499-511
Journal of neurosurgery 2021 Feb 1;134(2):499-511
Compound Kushen Injection intervenes metabolic reprogramming and epithelial-mesenchymal transition of HCC via regulating β-catenin/c-Myc signaling.
Wang KX, Du GH, Qin XM, Gao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153781
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153781
Simiao Qingwen Baidu decoction inhibits Epstein-Barr virus-induced B lymphoproliferative disease and lytic viral replication.
Yang X, Liu L, Zhang H, Sun X, Yan Y, Ran R
Pharmaceutical biology 2021 Dec;59(1):741-747
Pharmaceutical biology 2021 Dec;59(1):741-747
Development of a novel anti-liver fibrosis formula with luteolin, licochalcone A, aloe-emodin and acacetin by network pharmacology and transcriptomics analysis.
Zhou Y, Wu R, Cai FF, Zhou WJ, Lu YY, Zhang H, Chen QL, Sun MY, Su SB
Pharmaceutical biology 2021 Dec;59(1):1594-1606
Pharmaceutical biology 2021 Dec;59(1):1594-1606
O-GlcNAc modified-TIP60/KAT5 is required for PCK1 deficiency-induced HCC metastasis.
Liu R, Gou D, Xiang J, Pan X, Gao Q, Zhou P, Liu Y, Hu J, Wang K, Tang N
Oncogene 2021 Dec;40(50):6707-6719
Oncogene 2021 Dec;40(50):6707-6719
Long non-coding RNA KRT8P41/miR-193a-3p/FUBP1 axis modulates the proliferation and invasion of chordoma cells.
Wen H, Fu Y, Zhu Y, Tao S, Shang X, Li Z, You T, Zhang W
Journal of bone oncology 2021 Dec;31:100392
Journal of bone oncology 2021 Dec;31:100392
The endocytic pathway of Pt nanoclusters and their induced apoptosis of A549 and A549/Cis cells through c-Myc/p53 and Bcl-2/caspase-3 signaling pathways.
Zhao L, Li H, Huang X, Liu T, Xin Y, Xiao Z, Zhao W, Miao S, Chen J, Li Z, Mi Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112360
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112360
MiR-130a-3p suppresses colorectal cancer growth by targeting Wnt Family Member 1 (WNT1).
Song GL, Xiao M, Wan XY, Deng J, Ling JD, Tian YG, Li M, Yin J, Zheng RY, Tang Y, Liu GY
Bioengineered 2021 Dec;12(1):8407-8418
Bioengineered 2021 Dec;12(1):8407-8418
Roles of WNT6 in Sheep Endometrial Epithelial Cell Cycle Progression and Uterine Glands Organogenesis.
Gao X, Yao X, Li X, Liang Y, Liu Z, Wang Z, Li K, Li Y, Zhang G, Wang F
Veterinary sciences 2021 Dec 9;8(12)
Veterinary sciences 2021 Dec 9;8(12)
Efferocytosis induces macrophage proliferation to help resolve tissue injury.
Gerlach BD, Ampomah PB, Yurdagul A Jr, Liu C, Lauring MC, Wang X, Kasikara C, Kong N, Shi J, Tao W, Tabas I
Cell metabolism 2021 Dec 7;33(12):2445-2463.e8
Cell metabolism 2021 Dec 7;33(12):2445-2463.e8
hsa_circ_0068631 promotes breast cancer progression through c-Myc by binding to EIF4A3.
Wang X, Chen M, Fang L
Molecular therapy. Nucleic acids 2021 Dec 3;26:122-134
Molecular therapy. Nucleic acids 2021 Dec 3;26:122-134
CCT8 recovers WTp53-suppressed cell cycle evolution and EMT to promote colorectal cancer progression.
Liao Q, Ren Y, Yang Y, Zhu X, Zhi Y, Zhang Y, Chen Y, Ding Y, Zhao L
Oncogenesis 2021 Dec 3;10(12):84
Oncogenesis 2021 Dec 3;10(12):84
miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling.
Peng J, Shi S, Yu J, Liu J, Wei H, Song H, Wang S, Li Z, He S, Li L, Zhang H, Yan Z, Zhao R, Liu Y, Liu Y, Li J, Zhang R, Wang W
Cancer cell international 2021 Dec 22;21(1):702
Cancer cell international 2021 Dec 22;21(1):702
Long non-coding RNA RP5-821D11.7 promotes proliferation, migration, and epithelial-mesenchymal transition in glioma and glioma stem-like cells.
Younis M, Shaikh S, Shahzad KA
Progress in biophysics and molecular biology 2021 Dec 21;
Progress in biophysics and molecular biology 2021 Dec 21;
Cyclophilin acts as a ribosome biogenesis factor by chaperoning the ribosomal protein (PlRPS15) in filamentous fungi.
Mo C, Xie C, Wang G, Tian T, Liu J, Zhu C, Xiao X, Xiao Y
Nucleic acids research 2021 Dec 2;49(21):12358-12376
Nucleic acids research 2021 Dec 2;49(21):12358-12376
LncRNA MIR155HG Promotes Temozolomide Resistance by Activating the Wnt/β-Catenin Pathway Via Binding to PTBP1 in Glioma.
He X, Sheng J, Yu W, Wang K, Zhu S, Liu Q
Cellular and molecular neurobiology 2021 Aug;41(6):1271-1284
Cellular and molecular neurobiology 2021 Aug;41(6):1271-1284
The novel interaction mode among centromere sub-complex CENP-O/P/U/Q/R.
Cao B, Zhao C, Zhang Y, Wang X, Ye J, Hu L, He X
Journal of molecular recognition : JMR 2021 Aug;34(8):e2892
Journal of molecular recognition : JMR 2021 Aug;34(8):e2892
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.
Xianjun F, Xirui X, Jie T, Huiwen M, Shaojun Z, Qiaoyun L, Yunxin L, Xuqun S
Journal of pharmacological sciences 2021 Aug;146(4):249-258
Journal of pharmacological sciences 2021 Aug;146(4):249-258
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Xie C, Zhou X, Liang C, Li X, Ge M, Chen Y, Yin J, Zhu J, Zhong C
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
N(6) -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness.
Lee J, Wu Y, Harada BT, Li Y, Zhao J, He C, Ma Y, Wu X
The EMBO journal 2021 Apr 15;40(8):e106276
The EMBO journal 2021 Apr 15;40(8):e106276
PD-L1 lncRNA splice isoform promotes lung adenocarcinoma progression via enhancing c-Myc activity.
Qu S, Jiao Z, Lu G, Yao B, Wang T, Rong W, Xu J, Fan T, Sun X, Yang R, Wang J, Yao Y, Xu G, Yan X, Wang T, Liang H, Zen K
Genome biology 2021 Apr 13;22(1):104
Genome biology 2021 Apr 13;22(1):104
MFN2 interacts with nuage-associated proteins and is essential for male germ cell development by controlling mRNA fate during spermatogenesis.
Wang X, Wen Y, Zhang J, Swanson G, Guo S, Cao C, Krawetz SA, Zhang Z, Yuan S
Development (Cambridge, England) 2021 Apr 1;148(7)
Development (Cambridge, England) 2021 Apr 1;148(7)
Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.
Yuan C, Yang D, Ma J, Yang J, Xue J, Song F, Liu X
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(8):e9488
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(8):e9488
THAP11 Functions as a Tumor Suppressor in Gastric Cancer through Regulating c-Myc Signaling Pathways.
Zhang J, Zhang H, Shi H, Wang F, Du J, Wang Y, Wei Y, Xue W, Li D, Feng Y, Yan J, Gao Y, Li J, Han J
BioMed research international 2020;2020:7838924
BioMed research international 2020;2020:7838924
Ginsenoside Rg1 Improves Differentiation by Inhibiting Senescence of Human Bone Marrow Mesenchymal Stem Cell via GSK-3β and β-Catenin.
Wang Z, Jiang R, Wang L, Chen X, Xiang Y, Chen L, Xiao M, Ling L, Wang Y
Stem cells international 2020;2020:2365814
Stem cells international 2020;2020:2365814
ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p.
Yuan Q, Yu H, Chen J, Song X, Sun L
Cancer cell international 2020;20:99
Cancer cell international 2020;20:99
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway.
Zhang R, Liu J, Zhang W, Hua L, Qian LT, Zhou SB
Cancer cell international 2020;20:20
Cancer cell international 2020;20:20
Identification of a Novel c-Myc Inhibitor 7594-0037 by Structure-Based Virtual Screening and Investigation of Its Anti-Cancer Effect on Multiple Myeloma.
Yao R, Xie Y, Sun X, Zhang M, Zhou J, Liu L, Gao J, Xu K
Drug design, development and therapy 2020;14:3983-3993
Drug design, development and therapy 2020;14:3983-3993
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Zhang X, Luo Y, Li Q
OncoTargets and therapy 2020;13:5819-5830
OncoTargets and therapy 2020;13:5819-5830
Combination of Inositol Hexaphosphate and Inositol Inhibits Liver Metastasis of Colorectal Cancer in Mice Through the Wnt/β-Catenin Pathway.
Liu X, Liu C, Chen C, Sun W, Ci Y, Li Q, Song Y
OncoTargets and therapy 2020;13:3223-3235
OncoTargets and therapy 2020;13:3223-3235
Antitumor Effect of miR-1294/Pyruvate Kinase M2 Signaling Cascade in Osteosarcoma Cells.
Yuan Q, Yu H, Chen J, Song X, Sun L
OncoTargets and therapy 2020;13:1637-1647
OncoTargets and therapy 2020;13:1637-1647
DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway.
Luo J, Luo X, Liu X, Fang Z, Xu J, Li L
OncoTargets and therapy 2020;13:1321-1330
OncoTargets and therapy 2020;13:1321-1330
Simultaneous Inhibition of Ornithine Decarboxylase 1 and Pyruvate Kinase M2 Exerts Synergistic Effects Against Hepatocellular Carcinoma Cells.
Zeng Z, Lan J, Lei S, Yang Y, He Z, Xue Y, Chen T
OncoTargets and therapy 2020;13:11697-11709
OncoTargets and therapy 2020;13:11697-11709
Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.
Guo W, Zhao L, Wei G, Liu P, Zhang Y, Fu L
Cancer management and research 2020;12:7291-7303
Cancer management and research 2020;12:7291-7303
Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features.
Mei Y, Cai D, Dai X
Journal of Cancer 2020;11(5):1162-1169
Journal of Cancer 2020;11(5):1162-1169
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Ren Y, Wang Y, Hao S, Yang Y, Xiong W, Qiu L, Tao J, Tang A
Journal of Cancer 2020;11(23):6939-6949
Journal of Cancer 2020;11(23):6939-6949
The M6A methyltransferase METTL3 promotes the development and progression of prostate carcinoma via mediating MYC methylation.
Yuan Y, Du Y, Wang L, Liu X
Journal of Cancer 2020;11(12):3588-3595
Journal of Cancer 2020;11(12):3588-3595
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
Meng F, Liu X, Lin C, Xu L, Liu J, Zhang P, Zhang X, Song J, Yan Y, Ren Z, Zhang Y
American journal of cancer research 2020;10(3):997-1011
American journal of cancer research 2020;10(3):997-1011
LncRNA CSMD1-1 promotes the progression of Hepatocellular Carcinoma by activating MYC signaling.
Liu J, Xu R, Mai SJ, Ma YS, Zhang MY, Cao PS, Weng NQ, Wang RQ, Cao D, Wei W, Guo RP, Zhang YJ, Xu L, Chen MS, Zhang HZ, Huang L, Fu D, Wang HY
Theranostics 2020;10(17):7527-7544
Theranostics 2020;10(17):7527-7544
Overexpression of miRNA-3613-3p Enhances the Sensitivity of Triple Negative Breast Cancer to CDK4/6 Inhibitor Palbociclib.
Yu Y, Liao H, Xie R, Zhang Y, Zheng R, Chen J, Zhang B
Frontiers in oncology 2020;10:590813
Frontiers in oncology 2020;10:590813
Long Non-coding RNA CCAT1 Acts as an Oncogene and Promotes Sunitinib Resistance in Renal Cell Carcinoma.
Shan L, Liu W, Zhan Y
Frontiers in oncology 2020;10:516552
Frontiers in oncology 2020;10:516552
USP9X promotes the proliferation, invasion and metastasis of liver cancer cells through regulating the JAK2/STAT3 signaling.
Song X, Yang W, Wu C, Han Y, Lu Y
Oncology letters 2020 Sep;20(3):2897-2905
Oncology letters 2020 Sep;20(3):2897-2905
Synthesis, docking studies and antitumor activity of phenanthroimidazole derivatives as promising c-myc G-quadruplex DNA stabilizers.
Wu Q, Song Y, Liu R, Wang R, Mei W, Chen W, Yang H, Wang X
Bioorganic chemistry 2020 Sep;102:104074
Bioorganic chemistry 2020 Sep;102:104074
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
Guo X, Dai X, Liu J, Cheng A, Qin C, Wang Z
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
Long non-coding RNA LPP-AS2 promotes glioma tumorigenesis via miR-7-5p/EGFR/PI3K/AKT/c-MYC feedback loop.
Zhang X, Niu W, Mu M, Hu S, Niu C
Journal of experimental & clinical cancer research : CR 2020 Sep 22;39(1):196
Journal of experimental & clinical cancer research : CR 2020 Sep 22;39(1):196
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
Yu G, Liu P, Shi Y, Li S, Liu Y, Fan Z, Zhu W
Journal of neurosurgery 2020 Sep 1;133(3):918-926
Journal of neurosurgery 2020 Sep 1;133(3):918-926
sATP‑binding cassette subfamily G member 2 enhances the multidrug resistance properties of human nasal natural killer/T cell lymphoma side population cells.
Wu S, Zhang X, Dong M, Yang Z, Zhang M, Chen Q
Oncology reports 2020 Oct;44(4):1467-1478
Oncology reports 2020 Oct;44(4):1467-1478
Let-7b downgrades CCND1 to repress osteogenic proliferation and differentiation of MC3T3-E1 cells: An implication in osteoporosis.
Wang LJ, Cai HQ
The Kaohsiung journal of medical sciences 2020 Oct;36(10):775-785
The Kaohsiung journal of medical sciences 2020 Oct;36(10):775-785
Fatty acid synthase contributes to epithelial-mesenchymal transition and invasion of salivary adenoid cystic carcinoma through PRRX1/Wnt/β-catenin pathway.
Zhang WL, Wang SS, Jiang YP, Liu Y, Yu XH, Wu JB, Wang K, Pang X, Liao P, Liang XH, Tang YL
Journal of cellular and molecular medicine 2020 Oct;24(19):11465-11476
Journal of cellular and molecular medicine 2020 Oct;24(19):11465-11476
STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.
Zhou C, Qian X, Hu M, Zhang R, Liu N, Huang Y, Yang J, Zhang J, Bai H, Yang Y, Wang Y, Ali D, Michalak M, Chen XZ, Tang J
Autophagy 2020 Oct;16(10):1786-1806
Autophagy 2020 Oct;16(10):1786-1806
Cancer-associated fibroblasts-derived exosomal miR-17-5p promotes colorectal cancer aggressive phenotype by initiating a RUNX3/MYC/TGF-β1 positive feedback loop.
Zhang Y, Wang S, Lai Q, Fang Y, Wu C, Liu Y, Li Q, Wang X, Gu C, Chen J, Cai J, Li A, Liu S
Cancer letters 2020 Oct 28;491:22-35
Cancer letters 2020 Oct 28;491:22-35
JARID1B promotes colorectal cancer proliferation and Wnt/β-catenin signaling via decreasing CDX2 level.
Huang D, Xiao F, Hao H, Hua F, Luo Z, Huang Z, Li Q, Chen S, Cheng X, Zhang X, Fang W, Hu X, Liu F
Cell communication and signaling : CCS 2020 Oct 27;18(1):169
Cell communication and signaling : CCS 2020 Oct 27;18(1):169
Redox-responsive nanoplatform for codelivery of miR-519c and gemcitabine for pancreatic cancer therapy.
Xin X, Kumar V, Lin F, Kumar V, Bhattarai R, Bhatt VR, Tan C, Mahato RI
Science advances 2020 Nov;6(46)
Science advances 2020 Nov;6(46)
USP22 positively modulates ERα action via its deubiquitinase activity in breast cancer.
Wang S, Zhong X, Wang C, Luo H, Lin L, Sun H, Sun G, Zeng K, Zou R, Liu W, Sun N, Song H, Liu W, Zhang Q, Liao Z, Teng X, Zhou T, Sun X, Zhao Y
Cell death and differentiation 2020 Nov;27(11):3131-3145
Cell death and differentiation 2020 Nov;27(11):3131-3145
MSCs reduce airway remodeling in the lungs of asthmatic rats through the Wnt/β-catenin signaling pathway.
Song J, Zhu XM, Wei QY
European review for medical and pharmacological sciences 2020 Nov;24(21):11199-11211
European review for medical and pharmacological sciences 2020 Nov;24(21):11199-11211
Tumor-like features of gene expression and metabolic profiles in enlarged pancreatic islets are associated with impaired incretin-induced insulin secretion in obese diabetes: A study of Zucker fatty diabetes mellitus rat.
Hayami T, Yokoi N, Yamaguchi T, Honda K, Murao N, Takahashi H, Wang S, Seino Y, Kamiya H, Yabe D, Sweet IR, Mizoguchi A, Nakamura J, Seino S
Journal of diabetes investigation 2020 Nov;11(6):1434-1447
Journal of diabetes investigation 2020 Nov;11(6):1434-1447
Long noncoding RNA CMPK2 promotes colorectal cancer progression by activating the FUBP3-c-Myc axis.
Gao Q, Zhou R, Meng Y, Duan R, Wu L, Li R, Deng F, Lin C, Zhao L
Oncogene 2020 May;39(19):3926-3938
Oncogene 2020 May;39(19):3926-3938
The miRNA-149-5p/MyD88 axis is responsible for ursolic acid-mediated attenuation of the stemness and chemoresistance of non-small cell lung cancer cells.
Chen Q, Luo J, Wu C, Lu H, Cai S, Bao C, Liu D, Kong J
Environmental toxicology 2020 May;35(5):561-569
Environmental toxicology 2020 May;35(5):561-569
Lipid rafts are required for effective renal D(1) dopamine receptor function.
Tiu AC, Yang J, Asico LD, Konkalmatt P, Zheng X, Cuevas S, Wang X, Lee H, Mazhar M, Felder RA, Jose PA, Villar VAM
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 May;34(5):6999-7017
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 May;34(5):6999-7017
BMX activates Wnt/β-catenin signaling pathway to promote cell proliferation and migration in breast cancer.
Li K, Pan WT, Ma YB, Xu XL, Gao Y, He YQ, Wei L, Zhang JW
Breast cancer (Tokyo, Japan) 2020 May;27(3):363-371
Breast cancer (Tokyo, Japan) 2020 May;27(3):363-371
ALDH1A1 maintains the cancer stem-like cells properties of esophageal squamous cell carcinoma by activating the AKT signal pathway and interacting with β-catenin.
Wang W, He S, Zhang R, Peng J, Guo D, Zhang J, Xiang B, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109940
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109940
SOX1 promotes differentiation of nasopharyngeal carcinoma cells by activating retinoid metabolic pathway.
Lei XX, Liu Y, Wang JX, Cai Q, Yan M, He HP, Liu Q, Long ZJ, Guan Z
Cell death & disease 2020 May 7;11(5):331
Cell death & disease 2020 May 7;11(5):331
Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep.
Zhang R, Li Y, Jia K, Xu X, Li Y, Zhao Y, Zhang X, Zhang J, Liu G, Deng S, Lian Z
Cell death & disease 2020 May 29;11(5):407
Cell death & disease 2020 May 29;11(5):407
Inhibition of miR-9 decreases osteosarcoma cell proliferation.
Gang W, Tanjun W, Yong H, Jiajun Q, Yi Z, Hao H
Bosnian journal of basic medical sciences 2020 May 1;20(2):218-225
Bosnian journal of basic medical sciences 2020 May 1;20(2):218-225
δ-Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β-catenin nuclear localization and activating its downstream target genes.
Ju L, Shan L, Yin B, Song Y
Cancer medicine 2020 Mar;9(6):2201-2212
Cancer medicine 2020 Mar;9(6):2201-2212
MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B.
Chen T, Lei S, Zeng Z, Pan S, Zhang J, Xue Y, Sun Y, Lan J, Xu S, Mao D, Guo B
International journal of molecular medicine 2020 Mar;45(3):886-896
International journal of molecular medicine 2020 Mar;45(3):886-896
Auxiliary antitumor effects of fungal proteins from Hericium erinaceus by target on the gut microbiota.
Wang D, Zhu X, Tang X, Li H, Yizhen X, Chen D
Journal of food science 2020 Jun;85(6):1872-1890
Journal of food science 2020 Jun;85(6):1872-1890
RIC-seq for global in situ profiling of RNA-RNA spatial interactions.
Cai Z, Cao C, Ji L, Ye R, Wang D, Xia C, Wang S, Du Z, Hu N, Yu X, Chen J, Wang L, Yang X, He S, Xue Y
Nature 2020 Jun;582(7812):432-437
Nature 2020 Jun;582(7812):432-437
The role of miR-21/RECK in the inhibition of osteosarcoma by curcumin.
Zhou L, Lu Y, Liu JS, Long SZ, Liu HL, Zhang J, Zhang T
Molecular and cellular probes 2020 Jun;51:101534
Molecular and cellular probes 2020 Jun;51:101534
Effects of cisplatin on the proliferation, invasion and apoptosis of breast cancer cells following β‑catenin silencing.
Zhu X, Feng J, Fu W, Shu X, Wan X, Liu J
International journal of molecular medicine 2020 Jun;45(6):1838-1850
International journal of molecular medicine 2020 Jun;45(6):1838-1850
Endogenous thrombopoietin promotes non-small-cell lung carcinoma cell proliferation and migration by regulating EGFR signalling.
Zou Z, Fan X, Liu Y, Sun Y, Zhang X, Sun G, Li X, Xu S
Journal of cellular and molecular medicine 2020 Jun;24(12):6644-6657
Journal of cellular and molecular medicine 2020 Jun;24(12):6644-6657
Activator of thyroid and retinoid receptor increases sorafenib resistance in hepatocellular carcinoma by facilitating the Warburg effect.
Ma L, Liu W, Xu A, Ji Q, Ma Y, Tai Y, Wang Y, Shen C, Liu Y, Wang T, Han J, Zhao C
Cancer science 2020 Jun;111(6):2028-2040
Cancer science 2020 Jun;111(6):2028-2040
MGP Promotes Colon Cancer Proliferation by Activating the NF-κB Pathway through Upregulation of the Calcium Signaling Pathway.
Li X, Wei R, Wang M, Ma L, Zhang Z, Chen L, Guo Q, Guo S, Zhu S, Zhang S, Min L
Molecular therapy oncolytics 2020 Jun 26;17:371-383
Molecular therapy oncolytics 2020 Jun 26;17:371-383
Small Nucleolar RNAs Determine Resistance to Doxorubicin in Human Osteosarcoma.
Godel M, Morena D, Ananthanarayanan P, Buondonno I, Ferrero G, Hattinger CM, Di Nicolantonio F, Serra M, Taulli R, Cordero F, Riganti C, Kopecka J
International journal of molecular sciences 2020 Jun 24;21(12)
International journal of molecular sciences 2020 Jun 24;21(12)
SNHG11 promotes cell proliferation in colorectal cancer by forming a positive regulatory loop with c-Myc.
Huang W, Dong S, Cha Y, Yuan X
Biochemical and biophysical research communications 2020 Jul 5;527(4):985-992
Biochemical and biophysical research communications 2020 Jul 5;527(4):985-992
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Zhou C, Yi C, Yi Y, Qin W, Yan Y, Dong X, Zhang X, Huang Y, Zhang R, Wei J, Ali DW, Michalak M, Chen XZ, Tang J
Molecular cancer 2020 Jul 29;19(1):118
Molecular cancer 2020 Jul 29;19(1):118
Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.
Wang B, Ye Q, Zou C
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 14;26:e923507
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 14;26:e923507
ApoE mimetic peptide targeted nanoparticles carrying a BRD4 inhibitor for treating Medulloblastoma in mice.
Wang Q, Kumar V, Lin F, Sethi B, Coulter DW, McGuire TR, Mahato RI
Journal of controlled release : official journal of the Controlled Release Society 2020 Jul 10;323:463-474
Journal of controlled release : official journal of the Controlled Release Society 2020 Jul 10;323:463-474
miR-744-5p mediates lncRNA HOTTIP to regulate the proliferation and apoptosis of papillary thyroid carcinoma cells.
Yuan Q, Fan Y, Liu Z, Wang X, Jia M, Geng Z, Zheng J, Lu X
Experimental cell research 2020 Jul 1;392(1):112024
Experimental cell research 2020 Jul 1;392(1):112024
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Yang F, Li S, Cheng Y, Li J, Han X
Life sciences 2020 Jul 1;252:117611
Life sciences 2020 Jul 1;252:117611
Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter.
Jiang W, Yan Y, Chen M, Luo G, Hao J, Pan J, Hu S, Guo P, Li W, Wang R, Zuo Y, Sun Y, Sui S, Yu W, Pan Z, Zou K, Zheng Z, Deng W, Wu X, Guo W
Aging 2020 Jan 6;12(1):611-627
Aging 2020 Jan 6;12(1):611-627
UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPKα2/mTORC1-MYC positive feedback loop.
Liu X, Ma F, Liu C, Zhu K, Li W, Xu Y, Li G, Niu Z, Liu J, Chen D, Li Z, Fu Y, Qian C
Cell death & disease 2020 Jan 6;11(1):10
Cell death & disease 2020 Jan 6;11(1):10
Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK signaling.
Sheng W, Shi X, Lin Y, Tang J, Jia C, Cao R, Sun J, Wang G, Zhou L, Dong M
Journal of experimental & clinical cancer research : CR 2020 Jan 17;39(1):16
Journal of experimental & clinical cancer research : CR 2020 Jan 17;39(1):16
60S acidic ribosomal protein P1 (RPLP1) is elevated in human endometriotic tissue and in a murine model of endometriosis and is essential for endometriotic epithelial cell survival in vitro.
Alali Z, Graham A, Swan K, Flyckt R, Falcone T, Cui W, Yang X, Christianson J, Nothnick WB
Molecular human reproduction 2020 Jan 1;26(1):53-64
Molecular human reproduction 2020 Jan 1;26(1):53-64
Deletion of FHL2 in fibroblasts attenuates fibroblasts activation and kidney fibrosis via restraining TGF-β1-induced Wnt/β-catenin signaling.
Duan Y, Qiu Y, Huang X, Dai C, Yang J, He W
Journal of molecular medicine (Berlin, Germany) 2020 Feb;98(2):291-307
Journal of molecular medicine (Berlin, Germany) 2020 Feb;98(2):291-307
Programmed cell death protein 1 promotes hepatitis B virus transmission through the regulation of ERK1/2-mediated trophoblasts differentiation.
Yang J, Liu J, Sheng M, Zhang X, Liu M
Archives of gynecology and obstetrics 2020 Feb;301(2):551-558
Archives of gynecology and obstetrics 2020 Feb;301(2):551-558
High mobility group AT-hook 2 and c-MYC as potential prognostic factors in pancreatic ductal adenocarcinoma.
Li K, Yang J, Chen J, Shi Y, Zhang Z, Chen W
Oncology letters 2020 Feb;19(2):1584-1592
Oncology letters 2020 Feb;19(2):1584-1592
Loss of RDM1 enhances hepatocellular carcinoma progression via p53 and Ras/Raf/ERK pathways.
Chen SL, Liu LL, Wang CH, Lu SX, Yang X, He YF, Zhang CZ, Yun JP
Molecular oncology 2020 Feb;14(2):373-386
Molecular oncology 2020 Feb;14(2):373-386
Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling.
Liu Y, Zhang M, He T, Yang W, Wang L, Zhang L, Guo M
Clinical epigenetics 2020 Feb 10;12(1):22
Clinical epigenetics 2020 Feb 10;12(1):22
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
Li N, Luo X, Yu Q, Yang P, Chen Z, Wang X, Jiang J, Xu J, Gong Q, Eizirik DL, Zhou Z, Zhao J, Xiong F, Zhang S, Wang CY
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807
Promotion of esophageal adenocarcinoma metastasis via Wnt/ß-catenin signal pathway by sorting nexins 3.
Pan B, Liu L, Hu X, Sun X, Zhu Y, Zhang T, Wei D, Guo Y, Shan J
Journal of gastroenterology and hepatology 2020 Dec;35(12):2131-2139
Journal of gastroenterology and hepatology 2020 Dec;35(12):2131-2139
Heat-Shock protein A12A is a novel PCNA-binding protein and promotes hepatocellular carcinoma growth.
Cheng H, Cao X, Min X, Zhang X, Kong Q, Mao Q, Li R, Xue B, Fang L, Liu L, Ding Z
The FEBS journal 2020 Dec;287(24):5464-5477
The FEBS journal 2020 Dec;287(24):5464-5477
MicroRNA-1236-3p inhibits human osteosarcoma growth.
Li J, Chen J, Hu Z, Xu W
Oncology letters 2020 Dec;20(6):367
Oncology letters 2020 Dec;20(6):367
Rab18 binds to classical swine fever virus NS5A and mediates viral replication and assembly in swine umbilical vein endothelial cells.
Zhang L, Zhao D, Jin M, Song M, Liu S, Guo K, Zhang Y
Virulence 2020 Dec;11(1):489-501
Virulence 2020 Dec;11(1):489-501
YTHDF1 Facilitates the Progression of Hepatocellular Carcinoma by Promoting FZD5 mRNA Translation in an m6A-Dependent Manner.
Liu X, Qin J, Gao T, Li C, He B, Pan B, Xu X, Chen X, Zeng K, Xu M, Zhu C, Pan Y, Sun H, Sun L, Xu T, Wang S
Molecular therapy. Nucleic acids 2020 Dec 4;22:750-765
Molecular therapy. Nucleic acids 2020 Dec 4;22:750-765
miR-4721, Induced by EBV-miR-BART22, Targets GSK3β to Enhance the Tumorigenic Capacity of NPC through the WNT/β-catenin Pathway.
Tang Z, Chen W, Xu Y, Lin X, Liu X, Li Y, Liu Y, Luo Z, Liu Z, Fang W, Zhao M
Molecular therapy. Nucleic acids 2020 Dec 4;22:557-571
Molecular therapy. Nucleic acids 2020 Dec 4;22:557-571
GEF-independent Ran activation shifts a fraction of the protein to the cytoplasm and promotes cell proliferation.
Zhou J, Tan Y, Zhang Y, Tong A, Shen X, Sun X, Jia D, Sun Q
Molecular biomedicine 2020 Dec 30;1(1):18
Molecular biomedicine 2020 Dec 30;1(1):18
Cyclin Y binds and activates CDK4 to promote the G1/S phase transition in hepatocellular carcinoma cells via Rb signaling.
Chen L, Wang X, Cheng H, Zhang W, Liu Y, Zeng W, Yu L, Huang C, Liu G
Biochemical and biophysical research communications 2020 Dec 17;533(4):1162-1169
Biochemical and biophysical research communications 2020 Dec 17;533(4):1162-1169
Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling.
Wang Y, Chen J, Chen J, Dong C, Yan X, Zhu Z, Lu P, Song Z, Liu H, Chen S
Toxicology and applied pharmacology 2020 Dec 15;409:115333
Toxicology and applied pharmacology 2020 Dec 15;409:115333
miR-140-3p enhances cisplatin sensitivity and attenuates stem cell-like properties through repressing Wnt/β-catenin signaling in lung adenocarcinoma cells.
Wu S, Wang H, Pan Y, Yang X, Wu D
Experimental and therapeutic medicine 2020 Aug;20(2):1664-1674
Experimental and therapeutic medicine 2020 Aug;20(2):1664-1674
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
Liu D, Zhang H, Cui M, Chen C, Feng Y
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
Ginsenoside Rh4 suppresses aerobic glycolysis and the expression of PD-L1 via targeting AKT in esophageal cancer.
Deng X, Zhao J, Qu L, Duan Z, Fu R, Zhu C, Fan D
Biochemical pharmacology 2020 Aug;178:114038
Biochemical pharmacology 2020 Aug;178:114038
Identification of Cardiac Glycosides as Novel Inhibitors of eIF4A1-Mediated Translation in Triple-Negative Breast Cancer Cells.
Howard CM, Estrada M, Terrero D, Tiwari AK, Raman D
Cancers 2020 Aug 4;12(8)
Cancers 2020 Aug 4;12(8)
KAP1 silencing relieves OxLDL-induced vascular endothelial dysfunction by down-regulating LOX-1.
Yan T, Liang C, Fan H, Zhou W, Huang L, Qi S, Wang W, Ma P
Bioscience reports 2020 Aug 28;40(8)
Bioscience reports 2020 Aug 28;40(8)
RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice.
Zhou Z, Ni J, Li J, Huo C, Miao N, Yin F, Cheng Q, Xu D, Xie H, Chen P, Zheng P, Zhang Y, Zhou L, Zhang W, Yu C, Liu J, Lu L
Journal of molecular medicine (Berlin, Germany) 2020 Apr;98(4):527-540
Journal of molecular medicine (Berlin, Germany) 2020 Apr;98(4):527-540
Apolipoprotein E2 modulates cell cycle function to promote proliferation in pancreatic cancer cells via regulation of the c-Myc-p21(Waf1) signalling pathway.
Du S, Wang H, Cai J, Ren R, Zhang W, Wei W, Shen X
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):191-202
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):191-202
Capsaicin suppressed activity of prostate cancer stem cells by inhibition of Wnt/β-catenin pathway.
Zhu M, Yu X, Zheng Z, Huang J, Yang X, Shi H
Phytotherapy research : PTR 2020 Apr;34(4):817-824
Phytotherapy research : PTR 2020 Apr;34(4):817-824
ACSL4 promotes hepatocellular carcinoma progression via c-Myc stability mediated by ERK/FBW7/c-Myc axis.
Chen J, Ding C, Chen Y, Hu W, Lu Y, Wu W, Zhang Y, Yang B, Wu H, Peng C, Xie H, Zhou L, Wu J, Zheng S
Oncogenesis 2020 Apr 29;9(4):42
Oncogenesis 2020 Apr 29;9(4):42
Overexpression of MEF2D contributes to oncogenic malignancy and chemotherapeutic resistance in ovarian carcinoma.
Li X, Zhang Y, Chai X, Zhou S, Zhang H, He J, Zhou R, Cai L, Chen L, Tao G
American journal of cancer research 2019;9(5):887-905
American journal of cancer research 2019;9(5):887-905
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
Wang Q, Jia S, Jiao Y, Xu L, Wang D, Chen X, Hu X, Liang H, Wen N, Zhang S, Guo B, Zhang L
International journal of medical sciences 2019;16(12):1573-1582
International journal of medical sciences 2019;16(12):1573-1582
FOXA1 is Prognostic of Triple Negative Breast Cancers by Transcriptionally Suppressing SOD2 and IL6.
Dai X, Cheng H, Chen X, Li T, Zhang J, Jin G, Cai D, Huang Z
International journal of biological sciences 2019;15(5):1030-1041
International journal of biological sciences 2019;15(5):1030-1041
SIRT6 promotes the Warburg effect of papillary thyroid cancer cell BCPAP through reactive oxygen species.
Yu W, Yang Z, Huang R, Min Z, Ye M
OncoTargets and therapy 2019;12:2861-2868
OncoTargets and therapy 2019;12:2861-2868
Berberine Inhibits Growth of Liver Cancer Cells by Suppressing Glutamine Uptake.
Zhang P, Wang Q, Lin Z, Yang P, Dou K, Zhang R
OncoTargets and therapy 2019;12:11751-11763
OncoTargets and therapy 2019;12:11751-11763
Overexpression of KRT17 promotes proliferation and invasion of non-small cell lung cancer and indicates poor prognosis.
Wang Z, Yang MQ, Lei L, Fei LR, Zheng YW, Huang WJ, Li ZH, Liu CC, Xu HT
Cancer management and research 2019;11:7485-7497
Cancer management and research 2019;11:7485-7497
FKN Facilitates HK-2 Cell EMT and Tubulointerstitial Lesions via the Wnt/β-Catenin Pathway in a Murine Model of Lupus Nephritis.
Fu D, Senouthai S, Wang J, You Y
Frontiers in immunology 2019;10:784
Frontiers in immunology 2019;10:784
The Anti-proliferative Activity of GnRH Through Downregulation of the Akt/ERK Pathways in Pancreatic Cancer.
Suo L, Chang X, Xu N, Ji H
Frontiers in endocrinology 2019;10:370
Frontiers in endocrinology 2019;10:370
MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.
Tian F, Yu C, Wu M, Wu X, Wan L, Zhu X
Cell proliferation 2019 Sep;52(5):e12635
Cell proliferation 2019 Sep;52(5):e12635
DEPDC1 drives hepatocellular carcinoma cell proliferation, invasion and angiogenesis by regulating the CCL20/CCR6 signaling pathway.
Guo W, Li H, Liu H, Ma X, Yang S, Wang Z
Oncology reports 2019 Sep;42(3):1075-1089
Oncology reports 2019 Sep;42(3):1075-1089
A positive feedback loop of SIRT1 and miR17HG promotes the repair of DNA double-stranded breaks.
Xie L, Huang R, Liu S, Wu W, Su A, Li R, Liu X, Lei Y, Sun H, Liu X, Xu S
Cell cycle (Georgetown, Tex.) 2019 Sep;18(17):2110-2123
Cell cycle (Georgetown, Tex.) 2019 Sep;18(17):2110-2123
HOXA11-AS regulates JAK-STAT pathway by miR-15a-3p/STAT3 axis to promote the growth and metastasis in liver cancer.
Wang S, Zhang S, He Y, Huang X, Hui Y, Tang Y
Journal of cellular biochemistry 2019 Sep;120(9):15941-15951
Journal of cellular biochemistry 2019 Sep;120(9):15941-15951
LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis.
Hua Q, Jin M, Mi B, Xu F, Li T, Zhao L, Liu J, Huang G
Journal of hematology & oncology 2019 Sep 5;12(1):91
Journal of hematology & oncology 2019 Sep 5;12(1):91
Regulation of circadian rhythms by NEAT1 mediated TMAO-induced endothelial proliferation: A protective role of asparagus extract.
Wu X, Chen L, Zeb F, Huang Y, An J, Ren J, Yang F, Feng Q
Experimental cell research 2019 Sep 1;382(1):111451
Experimental cell research 2019 Sep 1;382(1):111451
MCP-induced protein 1 attenuates sepsis-induced acute lung injury by modulating macrophage polarization via the JNK/c-Myc pathway.
Zhang Y, Huang T, Jiang L, Gao J, Yu D, Ge Y, Lin S
International immunopharmacology 2019 Oct;75:105741
International immunopharmacology 2019 Oct;75:105741
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway.
Wen N, Guo B, Zheng H, Xu L, Liang H, Wang Q, Wang D, Chen X, Zhang S, Li Y, Zhang L
International journal of oncology 2019 Oct;55(4):879-895
International journal of oncology 2019 Oct;55(4):879-895
HMQ‑T‑F2 suppresses migration of the human cervical cancer HeLa cells by reversing EMT via the PI3K/Akt signaling pathway.
Dai B, Yu R, Fan M, Yang T, Wang B, Zhang Y
Oncology reports 2019 Oct;42(4):1451-1458
Oncology reports 2019 Oct;42(4):1451-1458
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Zhang Q, Cao WS, Wang XQ, Zhang M, Lu XM, Chen JQ, Chen Y, Ge MM, Zhong CY, Han HY
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
A novel oncogene TRIM63 promotes cell proliferation and migration via activating Wnt/β-catenin signaling pathway in breast cancer.
Li K, Pan W, Ma Y, Xu X, Gao Y, He Y, Wei L, Zhang J
Pathology, research and practice 2019 Oct;215(10):152573
Pathology, research and practice 2019 Oct;215(10):152573
SIRT4 enhances the sensitivity of ER-positive breast cancer to tamoxifen by inhibiting the IL-6/STAT3 signal pathway.
Xing J, Li J, Fu L, Gai J, Guan J, Li Q
Cancer medicine 2019 Nov;8(16):7086-7097
Cancer medicine 2019 Nov;8(16):7086-7097
lncRNA MALAT1 mediated high glucose-induced HK-2 cell epithelial-to-mesenchymal transition and injury.
Zhang J, Jiang T, Liang X, Shu S, Xiang X, Zhang W, Guo T, Xie W, Deng W, Tang X
Journal of physiology and biochemistry 2019 Nov;75(4):443-452
Journal of physiology and biochemistry 2019 Nov;75(4):443-452
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
Lanxiang W, Bin W, Ge X, Yutang H, Chunjie W, Honghao Z
Toxicology mechanisms and methods 2019 Nov;29(9):686-692
Toxicology mechanisms and methods 2019 Nov;29(9):686-692
Usp10 Modulates the Hippo Pathway by Deubiquitinating and Stabilizing the Transcriptional Coactivator Yorkie.
Gao Y, Zhang X, Xiao L, Zhai C, Yi T, Wang G, Wang E, Ji X, Hu L, Shen G, Wu S
International journal of molecular sciences 2019 Nov 29;20(23)
International journal of molecular sciences 2019 Nov 29;20(23)
Targeting Frizzled-7 Decreases Stemness and Chemotherapeutic Resistance in Gastric Cancer Cells by Suppressing Myc Expression.
Cheng Y, Li L, Pan S, Jiang H, Jin H
Medical science monitor : international medical journal of experimental and clinical research 2019 Nov 16;25:8637-8644
Medical science monitor : international medical journal of experimental and clinical research 2019 Nov 16;25:8637-8644
A novel tumor suppressor SPINK5 targets Wnt/β-catenin signaling pathway in esophageal cancer.
Wang Q, Lv Q, Bian H, Yang L, Guo KL, Ye SS, Dong XF, Tao LL
Cancer medicine 2019 May;8(5):2360-2371
Cancer medicine 2019 May;8(5):2360-2371
MYC status as a determinant of synergistic response to Olaparib and Palbociclib in ovarian cancer.
Yi J, Liu C, Tao Z, Wang M, Jia Y, Sang X, Shen L, Xue Y, Jiang K, Luo F, Liu P, Cheng H
EBioMedicine 2019 May;43:225-237
EBioMedicine 2019 May;43:225-237
Dennd1a, a susceptibility gene for polycystic ovary syndrome, is essential for mouse embryogenesis.
Shi J, Gao Q, Cao Y, Fu J
Developmental dynamics : an official publication of the American Association of Anatomists 2019 May;248(5):351-362
Developmental dynamics : an official publication of the American Association of Anatomists 2019 May;248(5):351-362
A novel inhibitor of nuclear factor kappa-B kinase subunit gamma mutation identified in an incontinentia pigmenti patient with syndromic tooth agenesis.
Sun S, Li F, Liu Y, Qu H, Wong SW, Zeng L, Yu M, Feng H, Liu H, Han D
Archives of oral biology 2019 May;101:100-107
Archives of oral biology 2019 May;101:100-107
USP36 protects proximal tubule cells from ischemic injury by stabilizing c-Myc and SOD2.
Liu Q, Sheng W, Ma Y, Zhen J, Roy S, Alvira Jafar C, Xin W, Wan Q
Biochemical and biophysical research communications 2019 May 28;513(2):502-508
Biochemical and biophysical research communications 2019 May 28;513(2):502-508
A Molecular Targeted Immunotherapeutic Strategy for Ulcerative Colitis via Dual-targeting Nanoparticles Delivering miR-146b to Intestinal Macrophages.
Deng F, He S, Cui S, Shi Y, Tan Y, Li Z, Huang C, Liu D, Zhi F, Peng L
Journal of Crohn's & colitis 2019 Mar 30;13(4):482-494
Journal of Crohn's & colitis 2019 Mar 30;13(4):482-494
H(2)S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling.
Zhang Y, Gao J, Sun W, Wen X, Xi Y, Wang Y, Wei C, Xu C, Li H
Aging 2019 Mar 26;11(6):1745-1758
Aging 2019 Mar 26;11(6):1745-1758
STAT1-mediated inhibition of FOXM1 enhances gemcitabine sensitivity in pancreatic cancer.
Liu C, Shi J, Li Q, Li Z, Lou C, Zhao Q, Zhu Y, Zhan F, Lian J, Wang B, Guan X, Fang L, Li Z, Wang Y, Zhou B, Yao Y, Zhang Y
Clinical science (London, England : 1979) 2019 Mar 15;133(5):645-663
Clinical science (London, England : 1979) 2019 Mar 15;133(5):645-663
MIR17HG-miR-18a/19a axis, regulated by interferon regulatory factor-1, promotes gastric cancer metastasis via Wnt/β-catenin signalling.
Yuan J, Tan L, Yin Z, Zhu W, Tao K, Wang G, Shi W, Gao J
Cell death & disease 2019 Jun 11;10(6):454
Cell death & disease 2019 Jun 11;10(6):454
AKIP1 promotes early recurrence of hepatocellular carcinoma through activating the Wnt/β-catenin/CBP signaling pathway.
Cui Y, Wu X, Lin C, Zhang X, Ye L, Ren L, Chen M, Yang M, Li Y, Li M, Li J, Guan J, Song L
Oncogene 2019 Jul;38(27):5516-5529
Oncogene 2019 Jul;38(27):5516-5529
Myc and Dnmt1 impede the pluripotent to totipotent state transition in embryonic stem cells.
Fu X, Wu X, Djekidel MN, Zhang Y
Nature cell biology 2019 Jul;21(7):835-844
Nature cell biology 2019 Jul;21(7):835-844
Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma.
Deng L, Sun J, Chen X, Liu L, Wu D
Journal of experimental & clinical cancer research : CR 2019 Jul 18;38(1):316
Journal of experimental & clinical cancer research : CR 2019 Jul 18;38(1):316
Function of BRD4 in the pathogenesis of high glucose‑induced cardiac hypertrophy.
Wang Q, Sun Y, Li T, Liu L, Zhao Y, Li L, Zhang L, Meng Y
Molecular medicine reports 2019 Jan;19(1):499-507
Molecular medicine reports 2019 Jan;19(1):499-507
FOXC1 silencing inhibits the epithelial‑to‑mesenchymal transition of glioma cells: Involvement of β‑catenin signaling.
Cao Q, Wang X, Shi Y, Zhang M, Yang J, Dong M, Mi Y, Zhang Z, Liu K, Jiang L, Wang N, Wang P
Molecular medicine reports 2019 Jan;19(1):251-261
Molecular medicine reports 2019 Jan;19(1):251-261
LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway.
Wei C, Dong X, Lu H, Tong F, Chen L, Zhang R, Dong J, Hu Y, Wu G, Dong X
Journal of experimental & clinical cancer research : CR 2019 Feb 21;38(1):95
Journal of experimental & clinical cancer research : CR 2019 Feb 21;38(1):95
Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis.
Ma Z, Cui X, Lu L, Chen G, Yang Y, Hu Y, Lu Y, Cao Z, Wang Y, Wang X
Stem cell research & therapy 2019 Feb 15;10(1):60
Stem cell research & therapy 2019 Feb 15;10(1):60
p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.
Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson FS, Tepper J, Chen Z, Lovisa S, Svelto M, Amin S, Srinivasan S, Del Poggetto E, Loponte S, Puca F, Dey P, Malouf GG, Su X, Li L, Lopez-Terrada D, Rakheja D, Lazar AJ, Netto GJ, Rao P, Sgambato A, Maitra A, Tripathi DN, Walker CL, Karam JA, Heffernan TP, Viale A, Roberts CWM, Msaouel P, Tannir NM, Draetta GF, Genovese G
Cancer cell 2019 Feb 11;35(2):204-220.e9
Cancer cell 2019 Feb 11;35(2):204-220.e9
TRIP13 promotes the cell proliferation, migration and invasion of glioblastoma through the FBXW7/c-MYC axis.
Zhang G, Zhu Q, Fu G, Hou J, Hu X, Cao J, Peng W, Wang X, Chen F, Cui H
British journal of cancer 2019 Dec;121(12):1069-1078
British journal of cancer 2019 Dec;121(12):1069-1078
LncRNA AC007271.3 promotes cell proliferation, invasion, migration and inhibits cell apoptosis of OSCC via the Wnt/β-catenin signaling pathway.
Shao TR, Zheng ZN, Chen YC, Wu QQ, Huang GZ, Li F, Zeng WS, Lv XZ
Life sciences 2019 Dec 15;239:117087
Life sciences 2019 Dec 15;239:117087
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice.
Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, Sands N, O'Connell D, Restrepo-Vassalli S, Chai B, Nemecio D, Punj V, Akbari O, Idos GE, Mumenthaler SM, Wu N, Martin SE, Hagiya A, Hicks J, Cui H, Liang C
Nature communications 2019 Dec 12;10(1):5681
Nature communications 2019 Dec 12;10(1):5681
Carboxypeptidase E-ΔN promotes migration, invasiveness, and epithelial-mesenchymal transition of human osteosarcoma cells via the Wnt-β-catenin pathway.
Fan S, Gao X, Chen P, Li X
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Aug;97(4):446-453
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Aug;97(4):446-453
miR-10b promoted melanoma progression through Wnt/β-catenin pathway by repressing ITCH expression.
Wang S, Wu Y, Xu Y, Tang X
Gene 2019 Aug 20;710:39-47
Gene 2019 Aug 20;710:39-47
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Liu Q, Guan Y, Li Z, Wang Y, Liu Y, Cui R, Wang Y
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Baicalin induced colon cancer cells apoptosis through miR-217/DKK1-mediated inhibition of Wnt signaling pathway.
Jia Y, Chen L, Guo S, Li Y
Molecular biology reports 2019 Apr;46(2):1693-1700
Molecular biology reports 2019 Apr;46(2):1693-1700
Enhanced expression of circular RNA hsa_circ_000984 promotes cells proliferation and metastasis in non-small cell lung cancer by modulating Wnt/β-catenin pathway.
Li XY, Liu YR, Zhou JH, Li W, Guo HH, Ma HP
European review for medical and pharmacological sciences 2019 Apr;23(8):3366-3374
European review for medical and pharmacological sciences 2019 Apr;23(8):3366-3374
ROS-Responsive Polymeric Micelles for Triggered Simultaneous Delivery of PLK1 Inhibitor/miR-34a and Effective Synergistic Therapy in Pancreatic Cancer.
Xin X, Lin F, Wang Q, Yin L, Mahato RI
ACS applied materials & interfaces 2019 Apr 24;11(16):14647-14659
ACS applied materials & interfaces 2019 Apr 24;11(16):14647-14659
Myricetin Suppresses the Propagation of Hepatocellular Carcinoma via Down-Regulating Expression of YAP.
Li M, Chen J, Yu X, Xu S, Li D, Zheng Q, Yin Y
Cells 2019 Apr 17;8(4)
Cells 2019 Apr 17;8(4)
P21-activated kinase 7 (PAK7) interacts with and activates Wnt/β-catenin signaling pathway in breast cancer.
Li K, Xu X, He Y, Tian Y, Pan W, Xu L, Ma Y, Gao Y, Gao J, Qi Y, Wei L, Zhang J
Journal of Cancer 2018;9(10):1821-1835
Journal of Cancer 2018;9(10):1821-1835
The Orexin-A-Regulated Akt/mTOR Pathway Promotes Cell Proliferation Through Inhibiting Apoptosis in Pancreatic Cancer Cells.
Suo L, Chang X, Zhao Y
Frontiers in endocrinology 2018;9:647
Frontiers in endocrinology 2018;9:647
Coagulation Factor X Regulated by CASC2c Recruited Macrophages and Induced M2 Polarization in Glioblastoma Multiforme.
Zhang Y, Feng J, Fu H, Liu C, Yu Z, Sun Y, She X, Li P, Zhao C, Liu Y, Liu T, Liu Q, Liu Q, Li G, Wu M
Frontiers in immunology 2018;9:1557
Frontiers in immunology 2018;9:1557
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
Wang Y, Tang H, He G, Shi Y, Kang X, Lyu J, Zhou M, Zhu M, Zhang J, Tang K
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2046-2059
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(6):2046-2059
R-spondin1/Wnt-enhanced Ascl2 autoregulation controls the self-renewal of colorectal cancer progenitor cells.
Ye J, Liu S, Shang Y, Chen H, Wang R
Cell cycle (Georgetown, Tex.) 2018;17(8):1014-1025
Cell cycle (Georgetown, Tex.) 2018;17(8):1014-1025
Plasma miR-199a-5p is increased in neutrophilic phenotype asthma patients and negatively correlated with pulmonary function.
Huang Y, Zhang S, Fang X, Qin L, Fan Y, Ding D, Liu X, Xie M
PloS one 2018;13(3):e0193502
PloS one 2018;13(3):e0193502
POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling.
Du Y, Li D, Li N, Su C, Yang C, Lin C, Chen M, Wu R, Li X, Hu G
Cell death & disease 2018 Sep 24;9(10):995
Cell death & disease 2018 Sep 24;9(10):995
Knockdown of Sox2 Inhibits OS Cells Invasion and Migration via Modulating Wnt/β-Catenin Signaling Pathway.
Tang L, Wang D, Gu D
Pathology oncology research : POR 2018 Oct;24(4):907-913
Pathology oncology research : POR 2018 Oct;24(4):907-913
Alpinetin inhibits proliferation and migration of ovarian cancer cells via suppression of STAT3 signaling.
Zhao X, Guo X, Shen J, Hua D
Molecular medicine reports 2018 Oct;18(4):4030-4036
Molecular medicine reports 2018 Oct;18(4):4030-4036
Identification of a novel c-Myc inhibitor with antitumor effects on multiple myeloma cells.
Yao R, Sun X, Xie Y, Sun X, Yao Y, Li H, Li Z, Gao J, Xu K
Bioscience reports 2018 Oct 31;38(5)
Bioscience reports 2018 Oct 31;38(5)
High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma.
Wu DJ, Jiang YS, He RZ, Tao LY, Yang MW, Fu XL, Yang JY, Zhu K
Scientific reports 2018 Oct 25;8(1):15792
Scientific reports 2018 Oct 25;8(1):15792
Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation.
Morita K, Hama Y, Izume T, Tamura N, Ueno T, Yamashita Y, Sakamaki Y, Mimura K, Morishita H, Shihoya W, Nureki O, Mano H, Mizushima N
The Journal of cell biology 2018 Nov 5;217(11):3817-3828
The Journal of cell biology 2018 Nov 5;217(11):3817-3828
Studying the mechanism of PLAGL2 overexpression and its carcinogenic characteristics based on 3'-untranslated region in colorectal cancer.
Su C, Li D, Li N, Du Y, Yang C, Bai Y, Lin C, Li X, Zhang Y
International journal of oncology 2018 May;52(5):1479-1490
International journal of oncology 2018 May;52(5):1479-1490
Inhibitory effects of aesculetin on the proliferation of colon cancer cells by the Wnt/β-catenin signaling pathway.
Li T, Zhang L, Huo X
Oncology letters 2018 May;15(5):7118-7122
Oncology letters 2018 May;15(5):7118-7122
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Li X, Meng Y, Xie C, Zhu J, Wang X, Li Y, Geng S, Wu J, Zhong C, Li M
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Journal of cellular biochemistry 2018 May;119(5):4134-4141
Annexin A5 regulates hepatocarcinoma malignancy via CRKI/II-DOCK180-RAC1 integrin and MEK-ERK pathways.
Sun X, Liu S, Wang J, Wei B, Guo C, Chen C, Sun MZ
Cell death & disease 2018 May 25;9(6):637
Cell death & disease 2018 May 25;9(6):637
c-MYC and reactive oxygen species play roles in tetrandrine-induced leukemia differentiation.
Wu G, Liu T, Li H, Li Y, Li D, Li W
Cell death & disease 2018 May 1;9(5):473
Cell death & disease 2018 May 1;9(5):473
Actin-capping protein CapG is associated with prognosis, proliferation and metastasis in human glioma.
Yun DP, Wang YQ, Meng DL, Ji YY, Chen JX, Chen HY, Lu DR
Oncology reports 2018 Mar;39(3):1011-1022
Oncology reports 2018 Mar;39(3):1011-1022
The ubiquitin ligase SCF(FBXW7α) promotes GATA3 degradation.
Song N, Cao C, Tang Y, Bi L, Jiang Y, Zhou Y, Song X, Liu L, Ge W
Journal of cellular physiology 2018 Mar;233(3):2366-2377
Journal of cellular physiology 2018 Mar;233(3):2366-2377
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Zhang Q, Li XT, Chen Y, Chen JQ, Zhu JY, Meng Y, Wang XQ, Li Y, Geng SS, Xie CF, Wu JS, Zhong CY, Han HY
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Cancer chemotherapy and pharmacology 2018 Jun;81(6):969-977
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
Jia W, Jiang X, Liu W, Wang L, Zhu B, Zhu H, Liu X, Zhong M, Xie D, Huang W, Jia W, Li S, Liu X, Zuo X, Cheng D, Dai J, Ren C
International journal of oncology 2018 Jun;52(6):1787-1800
International journal of oncology 2018 Jun;52(6):1787-1800
Atrazine exposure improves the proliferation of H22 cells in vitro and in vivo.
Tian Y, He J, Liu N, Huang D, Liu Z, Yang Y, Chen J, Zhao B, Zhao S, Liang B
RSC advances 2018 Jun 13;8(39):21759-21767
RSC advances 2018 Jun 13;8(39):21759-21767
LGR5 promotes epithelial ovarian cancer proliferation, metastasis, and epithelial-mesenchymal transition through the Notch1 signaling pathway.
Liu W, Zhang J, Gan X, Shen F, Yang X, Du N, Xia D, Liu L, Qiao L, Pan J, Sun Y, Xi X
Cancer medicine 2018 Jul;7(7):3132-3142
Cancer medicine 2018 Jul;7(7):3132-3142
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
Wang J, Chen J, Jiang Y, Shi Y, Zhu J, Xie C, Geng S, Wu J, Zhang Q, Wang X, Meng Y, Li Y, Chen Y, Cao W, Wang X, Zhong C, Li X
Toxicology letters 2018 Jul;291:70-76
Toxicology letters 2018 Jul;291:70-76
Nucleoside diphosphate kinase B promotes osteosarcoma proliferation through c-Myc.
Li S, Hu T, Yuan T, Cheng D, Yang Q
Cancer biology & therapy 2018 Jul 3;19(7):565-572
Cancer biology & therapy 2018 Jul 3;19(7):565-572
Ube2v1-mediated ubiquitination and degradation of Sirt1 promotes metastasis of colorectal cancer by epigenetically suppressing autophagy.
Shen T, Cai LD, Liu YH, Li S, Gan WJ, Li XM, Wang JR, Guo PD, Zhou Q, Lu XX, Sun LN, Li JM
Journal of hematology & oncology 2018 Jul 17;11(1):95
Journal of hematology & oncology 2018 Jul 17;11(1):95
Amphiphilic nanocarrier-induced modulation of PLK1 and miR-34a leads to improved therapeutic response in pancreatic cancer.
Gibori H, Eliyahu S, Krivitsky A, Ben-Shushan D, Epshtein Y, Tiram G, Blau R, Ofek P, Lee JS, Ruppin E, Landsman L, Barshack I, Golan T, Merquiol E, Blum G, Satchi-Fainaro R
Nature communications 2018 Jan 2;9(1):16
Nature communications 2018 Jan 2;9(1):16
High expression of TMEM40 is associated with the malignant behavior and tumorigenesis in bladder cancer.
Zhang ZF, Zhang HR, Zhang QY, Lai SY, Feng YZ, Zhou Y, Zheng SR, Shi R, Zhou JY
Journal of translational medicine 2018 Jan 19;16(1):9
Journal of translational medicine 2018 Jan 19;16(1):9
Ubiquitin-Specific Protease USP6 Regulates the Stability of the c-Jun Protein.
Li L, Yang H, He Y, Li T, Feng J, Chen W, Ao L, Shi X, Lin Y, Liu H, Zheng E, Lin Q, Bu J, Zeng Y, Zheng M, Xu Y, Liao Z, Lin J, Lin D
Molecular and cellular biology 2018 Jan 15;38(2)
Molecular and cellular biology 2018 Jan 15;38(2)
Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation.
Gao L, Wang KX, Zhou YZ, Fang JS, Qin XM, Du GH
Scientific reports 2018 Jan 12;8(1):624
Scientific reports 2018 Jan 12;8(1):624
MiR-17-5p enhances pancreatic cancer proliferation by altering cell cycle profiles via disruption of RBL2/E2F4-repressing complexes.
Zhu Y, Gu J, Li Y, Peng C, Shi M, Wang X, Wei G, Ge O, Wang D, Zhang B, Wu J, Zhong Y, Shen B, Chen H
Cancer letters 2018 Jan 1;412:59-68
Cancer letters 2018 Jan 1;412:59-68
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
Zhao B, Liu L, Mao J, Zhang Z, Wang Q, Li Q
Cell death & disease 2018 Feb 22;9(3):307
Cell death & disease 2018 Feb 22;9(3):307
NIT1 suppresses tumour proliferation by activating the TGFβ1-Smad2/3 signalling pathway in colorectal cancer.
Lin C, Zhang J, Lu Y, Li X, Zhang W, Zhang W, Lin W, Zheng L, Li X
Cell death & disease 2018 Feb 15;9(3):263
Cell death & disease 2018 Feb 15;9(3):263
Nalmefene attenuates malignant potential in colorectal cancer cell via inhibition of opioid receptor.
Wu Q, Chen X, Wang J, Sun P, Weng M, Chen W, Sun Z, Zhu M, Miao C
Acta biochimica et biophysica Sinica 2018 Feb 1;50(2):156-163
Acta biochimica et biophysica Sinica 2018 Feb 1;50(2):156-163
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Chen Y, Li Y, Wang XQ, Meng Y, Zhang Q, Zhu JY, Chen JQ, Cao WS, Wang XQ, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Phytotherapy research : PTR 2018 Dec;32(12):2447-2455
Cucurbitacin B Inhibits the Hippo-YAP Signaling Pathway and Exerts Anticancer Activity in Colorectal Cancer Cells.
Chai Y, Xiang K, Wu Y, Zhang T, Liu Y, Liu X, Zhen W, Si Y
Medical science monitor : international medical journal of experimental and clinical research 2018 Dec 19;24:9251-9258
Medical science monitor : international medical journal of experimental and clinical research 2018 Dec 19;24:9251-9258
Protein A from orange-spotted grouper nervous necrosis virus triggers type I interferon production in fish cell.
Huang R, Zhou Q, Shi Y, Zhang J, He J, Xie J
Fish & shellfish immunology 2018 Aug;79:234-243
Fish & shellfish immunology 2018 Aug;79:234-243
Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3β/β-catenin signaling pathway in breast cancer.
Li K, Ma YB, Zhang Z, Tian YH, Xu XL, He YQ, Xu L, Gao Y, Pan WT, Song WJ, He X, Wei L
Cancer medicine 2018 Aug;7(8):3875-3888
Cancer medicine 2018 Aug;7(8):3875-3888
Resveratrol inhibits the growth of gastric cancer via the Wnt/β-catenin pathway.
Dai H, Deng HB, Wang YH, Guo JJ
Oncology letters 2018 Aug;16(2):1579-1583
Oncology letters 2018 Aug;16(2):1579-1583
A novel Anti-Cancer Stem Cells compound optimized from the natural symplostatin 4 scaffold inhibits Wnt/β-catenin signaling pathway.
Liu S, Gao X, Zhang L, Qin S, Wei M, Liu N, Zhao R, Li B, Meng Y, Lin G, Lu C, Liu X, Xie M, Liu T, Zhou H, Qi M, Yang G, Yang C
European journal of medicinal chemistry 2018 Aug 5;156:21-42
European journal of medicinal chemistry 2018 Aug 5;156:21-42
Anticancer activity and potential mechanisms of 1C, a ginseng saponin derivative, on prostate cancer cells.
Wang X, Su GY, Zhao C, Qu FZ, Wang P, Zhao YQ
Journal of ginseng research 2018 Apr;42(2):133-143
Journal of ginseng research 2018 Apr;42(2):133-143
Overexpression of MYC binding protein promotes invasion and migration in gastric cancer.
Gong L, Xia Y, Qian Z, Shi J, Luo J, Song G, Xu J, Ye Z
Oncology letters 2018 Apr;15(4):5243-5249
Oncology letters 2018 Apr;15(4):5243-5249
Synergistic effect of receptor-interacting protein 140 and simvastatin on the inhibition of proliferation and survival of hepatocellular carcinoma cells.
Xia K, Zhang P, Hu J, Hou H, Xiong M, Xiong J, Yan N
Oncology letters 2018 Apr;15(4):4344-4350
Oncology letters 2018 Apr;15(4):4344-4350
Myosin 1b promotes cell proliferation, migration, and invasion in cervical cancer.
Zhang HR, Lai SY, Huang LJ, Zhang ZF, Liu J, Zheng SR, Ding K, Bai X, Zhou JY
Gynecologic oncology 2018 Apr;149(1):188-197
Gynecologic oncology 2018 Apr;149(1):188-197
Wnt signaling induces radioresistance through upregulating HMGB1 in esophageal squamous cell carcinoma.
Zhao Y, Yi J, Tao L, Huang G, Chu X, Song H, Chen L
Cell death & disease 2018 Apr 1;9(4):433
Cell death & disease 2018 Apr 1;9(4):433
Nuclear galectin-1-FOXP3 interaction dampens the tumor-suppressive properties of FOXP3 in breast cancer.
Gao Y, Li X, Shu Z, Zhang K, Xue X, Li W, Hao Q, Wang Z, Zhang W, Wang S, Zeng C, Fan D, Zhang W, Zhang Y, Zhao H, Li M, Zhang C
Cell death & disease 2018 Apr 1;9(4):416
Cell death & disease 2018 Apr 1;9(4):416
RIZ1 negatively regulates ubiquitin-conjugating enzyme E2C/UbcH10 via targeting c-Myc in meningioma.
Cai Z, Zou Y, Hu H, Lu C, Sun W, Jiang L, Hu G
American journal of translational research 2017;9(5):2645-2655
American journal of translational research 2017;9(5):2645-2655
Whole exome-wide association study identifies a missense variant in SLC2A4RG associated with glioblastoma risk.
Zhao Y, Yun D, Zou X, Jiang T, Li G, Hu L, Chen J, Xu J, Mao Y, Chen H, Lu D
American journal of cancer research 2017;7(9):1937-1947
American journal of cancer research 2017;7(9):1937-1947
β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.
Yu W, Li L, Zheng F, Yang W, Zhao S, Tian C, Yin W, Chen Y, Guo W, Zou L, Deng W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):467-478
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):467-478
Overexpression of CIP2A is associated with poor prognosis in multiple myeloma.
Liu X, Cao W, Qin S, Zhang T, Zheng J, Dong Y, Ming P, Cheng Q, Lu Z, Guo Y, Zhang B, Liu Y
Signal transduction and targeted therapy 2017;2:17013
Signal transduction and targeted therapy 2017;2:17013
Overexpression of SET oncoprotein is associated with tumor progression and poor prognosis in human gastric cancer.
Yuan X, Zhang T, Zheng X, Zhang Y, Feng T, Liu P, Sun Z, Qin S, Liu X, Zhang L, Song J, Liu Y
Oncology reports 2017 Sep;38(3):1733-1741
Oncology reports 2017 Sep;38(3):1733-1741
Lin28B facilitates the progression and metastasis of pancreatic ductal adenocarcinoma.
Wang Y, Li J, Guo S, Ouyang Y, Yin L, Liu S, Zhao Z, Yang J, Huang W, Qin H, Zhao X, Ni B, Wang H
Oncotarget 2017 Sep 1;8(36):60414-60428
Oncotarget 2017 Sep 1;8(36):60414-60428
Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication.
Wang T, Wang B, Huang H, Zhang C, Zhu Y, Pei B, Cheng C, Sun L, Wang J, Jin Q, Zhao Z
PLoS pathogens 2017 Oct;13(10):e1006674
PLoS pathogens 2017 Oct;13(10):e1006674
Synthesis and biological evaluation of 4-biphenylamino-5-halo-2(5H)-furanones as potential anticancer agents.
Wu YC, Luo SH, Mei WJ, Cao L, Wu HQ, Wang ZY
European journal of medicinal chemistry 2017 Oct 20;139:84-94
European journal of medicinal chemistry 2017 Oct 20;139:84-94
Epigenetic mediated zinc finger protein 671 downregulation promotes cell proliferation and tumorigenicity in nasopharyngeal carcinoma by inhibiting cell cycle arrest.
Zhang J, Wen X, Liu N, Li YQ, Tang XR, Wang YQ, He QM, Yang XJ, Zhang PP, Ma J, Sun Y
Journal of experimental & clinical cancer research : CR 2017 Oct 19;36(1):147
Journal of experimental & clinical cancer research : CR 2017 Oct 19;36(1):147
Axin1 up-regulated 1 accelerates stress-induced cardiomyocytes apoptosis through activating Wnt/β-catenin signaling.
Ye X, Lin J, Lin Z, Xue A, Li L, Zhao Z, Liu L, Shen Y, Cong B
Experimental cell research 2017 Oct 15;359(2):441-448
Experimental cell research 2017 Oct 15;359(2):441-448
Invasive Fusobacterium nucleatum activates beta-catenin signaling in colorectal cancer via a TLR4/P-PAK1 cascade.
Chen Y, Peng Y, Yu J, Chen T, Wu Y, Shi L, Li Q, Wu J, Fu X
Oncotarget 2017 May 9;8(19):31802-31814
Oncotarget 2017 May 9;8(19):31802-31814
Parkin regulates translesion DNA synthesis in response to UV radiation.
Zhu X, Ma X, Tu Y, Huang M, Liu H, Wang F, Gong J, Wang J, Li X, Chen Q, Shen H, Zhu S, Wang Y, Liu Y, Guo C, Tang TS
Oncotarget 2017 May 30;8(22):36423-36437
Oncotarget 2017 May 30;8(22):36423-36437
Correlations between TBL1XR1 and recurrence of colorectal cancer.
Liu H, Xu Y, Zhang Q, Li K, Wang D, Li S, Ning S, Yang H, Shi W, Liu Z, Chen Y
Scientific reports 2017 Mar 15;7:44275
Scientific reports 2017 Mar 15;7:44275
ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer.
Liang C, Qin Y, Zhang B, Ji S, Shi S, Xu W, Liu J, Xiang J, Liang D, Hu Q, Ni Q, Yu X, Xu J
Cancer letters 2017 Mar 1;388:303-311
Cancer letters 2017 Mar 1;388:303-311
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
Zhu J, Wang S, Chen Y, Li X, Jiang Y, Yang X, Li Y, Wang X, Meng Y, Zhu M, Ma X, Huang C, Wu R, Xie C, Geng S, Wu J, Zhong C, Han H
The Journal of nutritional biochemistry 2017 Jun;44:80-91
The Journal of nutritional biochemistry 2017 Jun;44:80-91
Apobec-1 complementation factor regulates cell migration and apoptosis through Dickkopf1 by acting on its 3' untranslated region in MCF7 cells.
Yan X, Li Q, Ni D, Xie Y, He Q, Wan Q, Liu Y, Lyu Z, Mao Z, Zhou Q
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jun;39(6):1010428317706218
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jun;39(6):1010428317706218
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Chen Y, Wang XQ, Zhang Q, Zhu JY, Li Y, Xie CF, Li XT, Wu JS, Geng SS, Zhong CY, Han HY
Nutrients 2017 Jun 3;9(6)
Nutrients 2017 Jun 3;9(6)
Methylation of DACT2 promotes breast cancer development by activating Wnt signaling.
Li J, Zhang M, He T, Li H, Cao T, Zheng L, Guo M
Scientific reports 2017 Jun 12;7(1):3325
Scientific reports 2017 Jun 12;7(1):3325
Hypoxia-inducible factor-2α promotes hepatocyte apoptosis during cholestasis.
Hua X, Lu T, Zhang J, Miao Q, Bian Z, Zhang H, Huang S, Lin W, Xi Z, Zhang M, Chen Q, Ma X, Zhang J, Xia Q
Hepatology research : the official journal of the Japan Society of Hepatology 2017 Jan;47(1):95-102
Hepatology research : the official journal of the Japan Society of Hepatology 2017 Jan;47(1):95-102
Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation.
Yao S, Xu F, Chen Y, Ge Y, Zhang F, Huang H, Li L, Lin D, Luo X, Xu J, Luo D, Zhu X, Liu Y
Journal of experimental & clinical cancer research : CR 2017 Jan 10;36(1):10
Journal of experimental & clinical cancer research : CR 2017 Jan 10;36(1):10
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Zhu J, Jiang Y, Yang X, Wang S, Xie C, Li X, Li Y, Chen Y, Wang X, Meng Y, Zhu M, Wu R, Huang C, Ma X, Geng S, Wu J, Zhong C
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
Biochemical and biophysical research communications 2017 Jan 1;482(1):15-21
Protective effect of autophagy in neural ischemia and hypoxia: Negative regulation of the Wnt/β-catenin pathway.
Shi ZY, Deng JX, Fu S, Wang L, Wang Q, Liu B, Li YQ, Deng JB
International journal of molecular medicine 2017 Dec;40(6):1699-1708
International journal of molecular medicine 2017 Dec;40(6):1699-1708
Knockdown of Rhotekin 2 expression suppresses proliferation and induces apoptosis in colon cancer cells.
Pang X, Li R, Shi D, Pan X, Ma C, Zhang G, Mu C, Chen W
Oncology letters 2017 Dec;14(6):8028-8034
Oncology letters 2017 Dec;14(6):8028-8034
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Wei X, Ye J, Shang Y, Chen H, Liu S, Liu L, Wang R
Oncotarget 2017 Dec 12;8(65):109301-109318
Oncotarget 2017 Dec 12;8(65):109301-109318
Autophagy plays an important role in stemness mediation and the novel dual function of EIG121 in both autophagy and stemness regulation of endometrial carcinoma JEC cells.
Ran X, Zhou P, Zhang K
International journal of oncology 2017 Aug;51(2):644-656
International journal of oncology 2017 Aug;51(2):644-656
miR-367 promotes tumor growth by inhibiting FBXW7 in NSCLC.
Xiao G, Gao X, Sun X, Yang C, Zhang B, Sun R, Huang G, Li X, Liu J, Du N, Liu D, Liang R, Ren H, Qin S
Oncology reports 2017 Aug;38(2):1190-1198
Oncology reports 2017 Aug;38(2):1190-1198
Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites.
Tang H, Yao X, Yao C, Zhao X, Zuo H, Li Z
Scientific reports 2017 Aug 8;7(1):7599
Scientific reports 2017 Aug 8;7(1):7599
CO-releasing molecules-2 attenuates ox-LDL-induced injury in HUVECs by ameliorating mitochondrial function and inhibiting Wnt/β-catenin pathway.
Sun HJ, Xu DY, Sun YX, Xue T, Zhang CX, Zhang ZX, Lin W, Li KX
Biochemical and biophysical research communications 2017 Aug 26;490(3):629-635
Biochemical and biophysical research communications 2017 Aug 26;490(3):629-635
Involvement of JNK signaling in IL4-induced M2 macrophage polarization.
Hao J, Hu Y, Li Y, Zhou Q, Lv X
Experimental cell research 2017 Aug 15;357(2):155-162
Experimental cell research 2017 Aug 15;357(2):155-162
GOLPH3 induces epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in epithelial ovarian cancer.
Sun J, Yang X, Zhang R, Liu S, Gan X, Xi X, Zhang Z, Feng Y, Sun Y
Cancer medicine 2017 Apr;6(4):834-844
Cancer medicine 2017 Apr;6(4):834-844
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Zhu JY, Yang X, Chen Y, Jiang Y, Wang SJ, Li Y, Wang XQ, Meng Y, Zhu MM, Ma X, Huang C, Wu R, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway.
Feng T, Zheng L, Liu F, Xu X, Mao S, Wang X, Liu J, Lu Y, Zhao W, Yu X, Tang W
Oncotarget 2016 Sep 6;7(36):58381-58395
Oncotarget 2016 Sep 6;7(36):58381-58395
Long non-coding RNA MINCR promotes gallbladder cancer progression through stimulating EZH2 expression.
Wang SH, Yang Y, Wu XC, Zhang MD, Weng MZ, Zhou D, Wang JD, Quan ZW
Cancer letters 2016 Sep 28;380(1):122-33
Cancer letters 2016 Sep 28;380(1):122-33
MicroRNA-146b, a Sensitive Indicator of Mesenchymal Stem Cell Repair of Acute Renal Injury.
Zhu Y, Yu J, Yin L, Zhou Y, Sun Z, Jia H, Tao Y, Liu W, Zhang B, Zhang J, Wang M, Zhang X, Yan Y, Xue J, Gu H, Mao F, Xu W, Qian H
Stem cells translational medicine 2016 Oct;5(10):1406-1415
Stem cells translational medicine 2016 Oct;5(10):1406-1415
CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis.
Zhuang K, Zhang J, Xiong M, Wang X, Luo X, Han L, Meng Y, Zhang Y, Liao W, Liu S
Cell death & disease 2016 Oct 13;7(10):e2415
Cell death & disease 2016 Oct 13;7(10):e2415
Atrazine promotes RM1 prostate cancer cell proliferation by activating STAT3 signaling.
Hu K, Tian Y, Du Y, Huang L, Chen J, Li N, Liu W, Liang Z, Zhao L
International journal of oncology 2016 May;48(5):2166-74
International journal of oncology 2016 May;48(5):2166-74
High expression of hexokinase domain containing 1 is associated with poor prognosis and aggressive phenotype in hepatocarcinoma.
Zhang Z, Huang S, Wang H, Wu J, Chen D, Peng B, Zhou Q
Biochemical and biophysical research communications 2016 Jun 10;474(4):673-679
Biochemical and biophysical research communications 2016 Jun 10;474(4):673-679
Aldehyde dehydrogenase 1A1 up-regulates stem cell markers in benzo[a]pyrene-induced malignant transformation of BEAS-2B cells.
Liu Y, Lu R, Gu J, Chen Y, Zhang X, Zhang L, Wu H, Hua W, Zeng J
Environmental toxicology and pharmacology 2016 Jul;45:241-50
Environmental toxicology and pharmacology 2016 Jul;45:241-50
High Expression of XRCC6 Promotes Human Osteosarcoma Cell Proliferation through the β-Catenin/Wnt Signaling Pathway and Is Associated with Poor Prognosis.
Zhu B, Cheng D, Li S, Zhou S, Yang Q
International journal of molecular sciences 2016 Jul 22;17(7)
International journal of molecular sciences 2016 Jul 22;17(7)
YPEL3 suppresses epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway.
Zhang J, Wen X, Ren XY, Li YQ, Tang XR, Wang YQ, He QM, Yang XJ, Sun Y, Liu N, Ma J
Journal of experimental & clinical cancer research : CR 2016 Jul 11;35(1):109
Journal of experimental & clinical cancer research : CR 2016 Jul 11;35(1):109
Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma.
Cui XB, Li S, Li TT, Peng H, Jin TT, Zhang SM, Liu CX, Yang L, Shen YY, Li SG, Li N, Li Y, Hu JM, Jiang JF, Suo J, Qi Y, Liang WH, Wang LH, Dang HW, Li L, Cao WW, Wei Y, Laibo-Yin, Wu CY, Yuan XL, Zhou H, Zheng Y, Chen YZ, Li F
Oncotarget 2016 Jan 12;7(2):1777-95
Oncotarget 2016 Jan 12;7(2):1777-95
Magnetic gold nanoparticle-mediated small interference RNA silencing Bag-1 gene for colon cancer therapy.
Huang W, Liu Z, Zhou G, Tian A, Sun N
Oncology reports 2016 Feb;35(2):978-84
Oncology reports 2016 Feb;35(2):978-84
Silencing Bag-1 gene via magnetic gold nanoparticle-delivered siRNA plasmid for colorectal cancer therapy in vivo and in vitro.
Huang W, Liu Z, Zhou G, Ling J, Tian A, Sun N
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Aug;37(8):10365-74
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Aug;37(8):10365-74
Cryptosporidium parvum rhomboid1 has an activity in microneme protein CpGP900 cleavage.
Li M, Zhang X, Gong P, Li J
Parasites & vectors 2016 Aug 8;9(1):438
Parasites & vectors 2016 Aug 8;9(1):438
Zeb1 Is a Potential Regulator of Six2 in the Proliferation, Apoptosis and Migration of Metanephric Mesenchyme Cells.
Gu Y, Zhao Y, Zhou Y, Xie Y, Ju P, Long Y, Liu J, Ni D, Cao F, Lyu Z, Mao Z, Hao J, Li Y, Wan Q, Kanyomse Q, Liu Y, Ren D, Ning Y, Li X, Zhou Q, Li B
International journal of molecular sciences 2016 Aug 6;17(8)
International journal of molecular sciences 2016 Aug 6;17(8)
PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway.
Gao H, Sun B, Fu H, Chi X, Wang F, Qi X, Hu J, Shao S
Oncotarget 2016 Aug 16;7(33):53289-53298
Oncotarget 2016 Aug 16;7(33):53289-53298
Loss-of-function Mutation in PMVK Causes Autosomal Dominant Disseminated Superficial Porokeratosis.
Wang J, Liu Y, Liu F, Huang C, Han S, Lv Y, Liu CJ, Zhang S, Qin Y, Ling L, Gao M, Yu S, Li C, Huang M, Liao S, Hu X, Lu Z, Liu X, Jiang T, Tang Z, Zhang H, Guo AY, Liu M
Scientific reports 2016 Apr 7;6:24226
Scientific reports 2016 Apr 7;6:24226
Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling.
Zhang M, Linghu E, Zhan Q, He T, Cao B, Brock MV, Herman JG, Xiang R, Guo M
Oncotarget 2016 Apr 5;7(14):17957-69
Oncotarget 2016 Apr 5;7(14):17957-69
Long Non-Coding RNA CCAT1 Acts as a Competing Endogenous RNA to Regulate Cell Growth and Differentiation in Acute Myeloid Leukemia.
Chen L, Wang W, Cao L, Li Z, Wang X
Molecules and cells 2016 Apr 30;39(4):330-6
Molecules and cells 2016 Apr 30;39(4):330-6
Overexpression of Long Non-Coding RNA ZXF2 Promotes Lung Adenocarcinoma Progression Through c-Myc Pathway.
Yang ZT, Li Z, Wang XG, Tan T, Yi F, Zhu H, Zhao JP, Zhou XF
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;35(6):2360-70
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;35(6):2360-70
FOXQ1 mediates the crosstalk between TGF-β and Wnt signaling pathways in the progression of colorectal cancer.
Peng X, Luo Z, Kang Q, Deng D, Wang Q, Peng H, Wang S, Wei Z
Cancer biology & therapy 2015;16(7):1099-109
Cancer biology & therapy 2015;16(7):1099-109
MiR-125a suppresses tumor growth, invasion and metastasis in cervical cancer by targeting STAT3.
Fan Z, Cui H, Xu X, Lin Z, Zhang X, Kang L, Han B, Meng J, Yan Z, Yan X, Jiao S
Oncotarget 2015 Sep 22;6(28):25266-80
Oncotarget 2015 Sep 22;6(28):25266-80
Low SFRP1 Expression Correlates with Poor Prognosis and Promotes Cell Invasion by Activating the Wnt/β-Catenin Signaling Pathway in NPC.
Ren XY, Zhou GQ, Jiang W, Sun Y, Xu YF, Li YQ, Tang XR, Wen X, He QM, Yang XJ, Liu N, Ma J
Cancer prevention research (Philadelphia, Pa.) 2015 Oct;8(10):968-77
Cancer prevention research (Philadelphia, Pa.) 2015 Oct;8(10):968-77
Senescent stromal cells induce cancer cell migration via inhibition of RhoA/ROCK/myosin-based cell contractility.
Aifuwa I, Giri A, Longe N, Lee SH, An SS, Wirtz D
Oncotarget 2015 Oct 13;6(31):30516-31
Oncotarget 2015 Oct 13;6(31):30516-31
Novel taspine derivative 12k inhibits cell growth and induces apoptosis in lung cell carcinoma.
Dai B, Wang W, Liu R, Wang H, Zhang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015 Mar;70:227-33
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015 Mar;70:227-33
Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells.
Chen XM, Xie XB, Zhao Q, Wang F, Bai Y, Yin JQ, Jiang H, Xie XL, Jia Q, Huang G
Molecular medicine reports 2015 Jan;11(1):105-12
Molecular medicine reports 2015 Jan;11(1):105-12
Mammalian cell display for rapid screening scFv antibody therapy.
Zhang J, Zhang X, Liu Q, Li M, Gao L, Gao X, Xiang S, Wu L, Fu J, Song H
Acta biochimica et biophysica Sinica 2014 Oct;46(10):859-66
Acta biochimica et biophysica Sinica 2014 Oct;46(10):859-66
MRTF-A and STAT3 synergistically promote breast cancer cell migration.
Liao XH, Wang N, Liu LY, Zheng L, Xing WJ, Zhao DW, Sun XG, Hu P, Dong J, Zhang TC
Cellular signalling 2014 Nov;26(11):2370-80
Cellular signalling 2014 Nov;26(11):2370-80
Hepatitis B viral RNA directly mediates down-regulation of the tumor suppressor microRNA miR-15a/miR-16-1 in hepatocytes.
Wang Y, Jiang L, Ji X, Yang B, Zhang Y, Fu XD
The Journal of biological chemistry 2013 Jun 21;288(25):18484-93
The Journal of biological chemistry 2013 Jun 21;288(25):18484-93
Expression and role of grainyhead-like 2 in gastric cancer.
Xiang J, Fu X, Ran W, Chen X, Hang Z, Mao H, Wang Z
Medical oncology (Northwood, London, England) 2013 Dec;30(4):714
Medical oncology (Northwood, London, England) 2013 Dec;30(4):714
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HL-60 cells were subjected to SDS PAGE followed by western blot with 10828-1-AP(MYC antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The c-MYC antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human c-MYC. This antibody recognizes human antigen. The c-MYC antibody has been validated for the following applications: ELISA, IHC, WB, IP analysis.
