NB600-336
antibody from Novus Biologicals
Targeting: MYC
bHLHe39, c-Myc, MYCC
Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [6]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- NB600-336 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB600-336, RRID:AB_10001777
- Product name
- Rabbit Polyclonal c-Myc Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references O-GlcNAc Transferase Regulates Cancer Stem-like Potential of Breast Cancer Cells.
Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis.
Structure and Membrane Binding Properties of the Endosomal Tetratricopeptide Repeat (TPR) Domain-containing Sorting Nexins SNX20 and SNX21.
Mycobacterium tuberculosis Hip1 modulates macrophage responses through proteolysis of GroEL2.
CEP120 interacts with CPAP and positively regulates centriole elongation.
Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly.
Replacement of charged and polar residues in the coiled-coiled interface of huntingtin-interacting protein 1 (HIP1) causes aggregation and cell death.
Epigenetic regulation of condensin-mediated genome organization during the cell cycle and upon DNA damage through histone H3 lysine 56 acetylation.
Differentiated embryo chondrocyte 1 (DEC1) represses PPARγ2 gene through interacting with CCAAT/enhancer binding protein β (C/EBPβ).
A translocator-specific export signal establishes the translocator-effector secretion hierarchy that is important for type III secretion system function.
The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation.
Depletion of antibiotic targets has widely varying effects on growth.
Autophagy and p62 in cardiac proteinopathy.
CPAP is a cell-cycle regulated protein that controls centriole length.
Rab6 regulates both ZW10/RINT-1 and conserved oligomeric Golgi complex-dependent Golgi trafficking and homeostasis.
Host genome surveillance for retrotransposons by transposon-derived proteins
Akella NM, Le Minh G, Ciraku L, Mukherjee A, Bacigalupa ZA, Mukhopadhyay D, Sodi VL, Reginato MJ
Molecular cancer research : MCR 2020 Apr;18(4):585-598
Molecular cancer research : MCR 2020 Apr;18(4):585-598
Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis.
Yang L, Liu Y, Wang M, Qian Y, Dong X, Gu H, Wang H, Guo S, Hisamitsu T
Molecular medicine reports 2016 Nov;14(5):4559-4566
Molecular medicine reports 2016 Nov;14(5):4559-4566
Structure and Membrane Binding Properties of the Endosomal Tetratricopeptide Repeat (TPR) Domain-containing Sorting Nexins SNX20 and SNX21.
Clairfeuille T, Norwood SJ, Qi X, Teasdale RD, Collins BM
The Journal of biological chemistry 2015 Jun 5;290(23):14504-17
The Journal of biological chemistry 2015 Jun 5;290(23):14504-17
Mycobacterium tuberculosis Hip1 modulates macrophage responses through proteolysis of GroEL2.
Naffin-Olivos JL, Georgieva M, Goldfarb N, Madan-Lala R, Dong L, Bizzell E, Valinetz E, Brandt GS, Yu S, Shabashvili DE, Ringe D, Dunn BM, Petsko GA, Rengarajan J
PLoS pathogens 2014 May;10(5):e1004132
PLoS pathogens 2014 May;10(5):e1004132
CEP120 interacts with CPAP and positively regulates centriole elongation.
Lin YN, Wu CT, Lin YC, Hsu WB, Tang CJ, Chang CW, Tang TK
The Journal of cell biology 2013 Jul 22;202(2):211-9
The Journal of cell biology 2013 Jul 22;202(2):211-9
Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly.
Lin YC, Chang CW, Hsu WB, Tang CJ, Lin YN, Chou EJ, Wu CT, Tang TK
The EMBO journal 2013 Apr 17;32(8):1141-54
The EMBO journal 2013 Apr 17;32(8):1141-54
Replacement of charged and polar residues in the coiled-coiled interface of huntingtin-interacting protein 1 (HIP1) causes aggregation and cell death.
Fontaine SN, Bauer SP, Lin X, Poorfarahani S, Ybe JA
FEBS letters 2012 Sep 21;586(19):3030-6
FEBS letters 2012 Sep 21;586(19):3030-6
Epigenetic regulation of condensin-mediated genome organization during the cell cycle and upon DNA damage through histone H3 lysine 56 acetylation.
Tanaka A, Tanizawa H, Sriswasdi S, Iwasaki O, Chatterjee AG, Speicher DW, Levin HL, Noguchi E, Noma K
Molecular cell 2012 Nov 30;48(4):532-46
Molecular cell 2012 Nov 30;48(4):532-46
Differentiated embryo chondrocyte 1 (DEC1) represses PPARγ2 gene through interacting with CCAAT/enhancer binding protein β (C/EBPβ).
Park YK, Park H
Molecules and cells 2012 Jun;33(6):575-81
Molecules and cells 2012 Jun;33(6):575-81
A translocator-specific export signal establishes the translocator-effector secretion hierarchy that is important for type III secretion system function.
Tomalka AG, Stopford CM, Lee PC, Rietsch A
Molecular microbiology 2012 Dec;86(6):1464-81
Molecular microbiology 2012 Dec;86(6):1464-81
The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation.
Tang CJ, Lin SY, Hsu WB, Lin YN, Wu CT, Lin YC, Chang CW, Wu KS, Tang TK
The EMBO journal 2011 Oct 21;30(23):4790-804
The EMBO journal 2011 Oct 21;30(23):4790-804
Depletion of antibiotic targets has widely varying effects on growth.
Wei JR, Krishnamoorthy V, Murphy K, Kim JH, Schnappinger D, Alber T, Sassetti CM, Rhee KY, Rubin EJ
Proceedings of the National Academy of Sciences of the United States of America 2011 Mar 8;108(10):4176-81
Proceedings of the National Academy of Sciences of the United States of America 2011 Mar 8;108(10):4176-81
Autophagy and p62 in cardiac proteinopathy.
Zheng Q, Su H, Ranek MJ, Wang X
Circulation research 2011 Jul 22;109(3):296-308
Circulation research 2011 Jul 22;109(3):296-308
CPAP is a cell-cycle regulated protein that controls centriole length.
Tang CJ, Fu RH, Wu KS, Hsu WB, Tang TK
Nature cell biology 2009 Jul;11(7):825-31
Nature cell biology 2009 Jul;11(7):825-31
Rab6 regulates both ZW10/RINT-1 and conserved oligomeric Golgi complex-dependent Golgi trafficking and homeostasis.
Sun Y, Shestakova A, Hunt L, Sehgal S, Lupashin V, Storrie B
Molecular biology of the cell 2007 Oct;18(10):4129-42
Molecular biology of the cell 2007 Oct;18(10):4129-42
Host genome surveillance for retrotransposons by transposon-derived proteins
Hugh P. Cam, Ken-ichi Noma, Hirotaka Ebina, Henry L. Levin, Shiv I. S. Grewal
Nature 2007 Dec;451(7177):431-436
Nature 2007 Dec;451(7177):431-436
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: c-Myc Antibody [NB600-336] - c-Myc in MOLT-4 cells. Image from verified customer review.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Simple Western: c-Myc Antibody [NB600-336] - Lane view shows a specific band for c-Myc in 0.05 mg/ml of Jurkat lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: c-Myc Antibody [NB600-336] - Analysis using the HRP conjugate of NB600-336. Detection of c-Myc in NIH/3T3 cell lysates (30ug and 45ug per lane) using anti-c-Myc antibody. Image from verified customer review.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: c-Myc Antibody [NB600-336] - Analysis of c-Myc on Jurkat whole cell extract using NB600-336.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: c-Myc Antibody [NB600-336] - Analysis of whole cell lysate (WCL) of Jurkat cells using anti-cMyc antibody (NB600-336) at 1:1000 dilution. HRP conjugated goat anti-rabbit IgG (H+L) cross adsorbed secondary antibody was used with ECL substrate for the detection of c-Myc antibody bound to the blotted protein. This c-Myc antibody detected the c-Myc specific band at its expected position (48-50kDa). The signal below 10 kDa in this blot is potentially the degraded protein and we have not characterized this band.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: c-Myc Antibody [NB600-336] - Detection of c-Myc in HtrA2-Myc Transfectant lysates .
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: c-Myc Antibody [NB600-336] - Analysis of c-Myc in mouse prostate using DAB with hematoxylin counterstain.