Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Other assay [1]
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Validation data
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- Product number
- V2744 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- c-Myc Antibody
- Antibody type
- Monoclonal
- Antigen
- Amino acids AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA were used as the immunogen for the c-Myc antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 9E10.3
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the c-Myc antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Nuclear C-MYC expression level is associated with disease progression and potentially predictive of two year overall survival in prostate cancer.
Hairy/Enhancer-of-Split MEGANE and Proneural MASH1 Factors Cooperate Synergistically in Midbrain GABAergic Neurogenesis.
MYC is expressed in the stromal and epithelial cells of primary breast carcinoma and paired nodal metastases.
Activation of ErbB2- ErbB3 signaling pathway supports potential therapeutic activity of ErbB inhibitors in AT/RT.
BCL2, BCL6, IGH, TP53, and MYC protein expression and gene rearrangements as prognostic markers in diffuse large B-cell lymphoma: a study of 44 Turkish patients.
EGFR and MYC gene copy number aberrations are more common in squamous cell carcinoma than keratoacanthoma: a FISH study.
MYC expression and distribution in normal mature lymphoid cells.
Circulating hepatitis B surface antigen particles carry hepatocellular microRNAs.
Methanol extract of the ethnopharmaceutical remedy Smilax spinosa exhibits anti-neoplastic activity.
De novo generation of a phosphate starvation-regulated promoter in Candida glabrata.
Zeng W, Sun H, Meng F, Liu Z, Xiong J, Zhou S, Li F, Hu J, Hu Z, Liu Z
International journal of clinical and experimental pathology 2015;8(2):1878-88
International journal of clinical and experimental pathology 2015;8(2):1878-88
Hairy/Enhancer-of-Split MEGANE and Proneural MASH1 Factors Cooperate Synergistically in Midbrain GABAergic Neurogenesis.
Wende CZ, Zoubaa S, Blak A, Echevarria D, Martinez S, Guillemot F, Wurst W, Guimera J
PloS one 2015;10(5):e0127681
PloS one 2015;10(5):e0127681
MYC is expressed in the stromal and epithelial cells of primary breast carcinoma and paired nodal metastases.
Mundim FG, Pasini FS, Brentani MM, Soares FA, Nonogaki S, Waitzberg AF
Molecular and clinical oncology 2015 May;3(3):506-514
Molecular and clinical oncology 2015 May;3(3):506-514
Activation of ErbB2- ErbB3 signaling pathway supports potential therapeutic activity of ErbB inhibitors in AT/RT.
Sredni ST, Patel K, D'Almeida Costa F, de Fátima Bonaldo M, Tomita T
Journal of neuro-oncology 2014 May;118(1):201-3
Journal of neuro-oncology 2014 May;118(1):201-3
BCL2, BCL6, IGH, TP53, and MYC protein expression and gene rearrangements as prognostic markers in diffuse large B-cell lymphoma: a study of 44 Turkish patients.
Akay OM, Aras BD, Isiksoy S, Toprak C, Mutlu FS, Artan S, Oner U, Gulbas Z
Cancer genetics 2014 Mar;207(3):87-93
Cancer genetics 2014 Mar;207(3):87-93
EGFR and MYC gene copy number aberrations are more common in squamous cell carcinoma than keratoacanthoma: a FISH study.
Jacobs MS, Persons DL, Fraga GR
Journal of cutaneous pathology 2013 May;40(5):447-54
Journal of cutaneous pathology 2013 May;40(5):447-54
MYC expression and distribution in normal mature lymphoid cells.
Cattoretti G
The Journal of pathology 2013 Feb;229(3):430-40
The Journal of pathology 2013 Feb;229(3):430-40
Circulating hepatitis B surface antigen particles carry hepatocellular microRNAs.
Novellino L, Rossi RL, Bonino F, Cavallone D, Abrignani S, Pagani M, Brunetto MR
PloS one 2012;7(3):e31952
PloS one 2012;7(3):e31952
Methanol extract of the ethnopharmaceutical remedy Smilax spinosa exhibits anti-neoplastic activity.
Seelinger M, Popescu R, Giessrigl B, Jarukamjorn K, Unger C, Wallnöfer B, Fritzer-Szekeres M, Szekeres T, Diaz R, Jäger W, Frisch R, Kopp B, Krupitza G
International journal of oncology 2012 Sep;41(3):1164-72
International journal of oncology 2012 Sep;41(3):1164-72
De novo generation of a phosphate starvation-regulated promoter in Candida glabrata.
Kerwin CL, Wykoff DD
FEMS yeast research 2012 Dec;12(8):980-9
FEMS yeast research 2012 Dec;12(8):980-9
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- Western blot testing of HeLa cell lysate (nuclear fraction) with c-Myc antibody (clone 9E10.3). Theoretical molecular weight: ~50kDa but routinely observed at 50~70kDa.
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of formalin-fixed, paraffin-embedded human cervical carcinoma stained with c-Myc antibody (9E10.3).
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free c-Myc Antibody (clone 9E10.3). Confirmation of Integrity and Purity of the Antibody.