orb385746

antibody from Biorbyt
Targeting: MYC bHLHe39, c-Myc, MYCC
Provider product page for orb385746
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
orb385746 - Provider product page
Provider
Biorbyt
Product name
c-Myc Antibody
Antibody type
Monoclonal
Description
The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
MYC275
Vial size
20 ug
Storage
Store the c-Myc antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
MYC protein structure - orb385746 shown in red.