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- Antigen structure
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- Product number
- 67447-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- c-Myc antibody
- Antibody type
- Monoclonal
- Description
- c-MYC antibody (Cat. #67447-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: FC, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3D9C12
- Vial size
- 20ul, 150ul
Submitted references CENPF Promotes Gastric Cancer Proliferation through c-Myc-Mediated GLS1 Upregulation and Glutamine Metabolism.
A biomimetic arsenic-based nanozyme enhances dual epigenetic regulation to improve the efficacy of immunotherapy for acute myeloid leukaemia.
ATP-binding cassette subfamily A member 5 suppresses pancreatic ductal adenocarcinoma progression and chemoresistance by promoting β-catenin ubiquitin-dependent degradation.
USP2 promotes metabolic dysfunction-associated steatotic liver disease progression via stabilization of PPARγ.
HHV-6A Drives Epigenetic Reprogramming via an EZH2-SIRT1 Axis to Sustain Mutant p53 and Reshape Oncogenic Inflammatory Signaling.
tRF-3005a regulates exon skipping of SPAG4 by interacting with RALY to drive gastric cancer progression.
Omics insights into MYBL2-promoted cancer stem-like cells driving ferroptosis resistance in hepatocellular carcinoma.
AMBP gene activation promotes cholangiocarcinoma progression through the WNT/β-catenin signaling pathway: Regulatory effect of polysaccharides from Auricularia auricula-judae.
Design, synthesis, and biological evaluation of selective cytotoxicity-derived Miliusol derivatives inducing profound TNBC regression in vivo.
Reticulon 3 deficiency induces ferroptosis via chaperone-mediated autophagy in ischemia-reperfusion induced acute kidney injury.
NRAV promotes HCC stemness via the m6A-regulated let-7c-5p/LIN28B axis.
MBD3 increased expression by BRD4 and facilitated castration-resistant prostate cancer cell proliferation by inhibiting PTEN.
The GFPT2/O-GlcNAcylation/c-Myc axis promotes bladder cancer progression.
FAM64A Potentiates Bladder Carcinoma Tumorigenesis and Metastasis Through PI3K/mTORC2/AKT Pathway Activation.
c-Myc/GRPEL1 maintains fatty acid synthesis via FASN to support PDAC cell proliferation.
KCTD15 Enhances Stem Cell-Like Properties and Promotes Triple-Negative Breast Cancer Progression Through KLF4/β-Catenin Signaling.
Functional characterization of CASP, a CUX1 isoform, reveals its tumor-promoting role in colorectal cancer via TRIM21-mediated signaling.
A pan-cancer single-cell transcriptomic atlas of human bone metastases.
RARG promotes gastric cancer progression by activating PMEPA1 transcription and Wnt/β-catenin signalling.
miRNA‑29a inhibits the proliferation of HUVECs by regulating the ITGB1/β‑catenin/c‑Myc pathway.
METTL16 promotes MASLD progression through the regulation of lipid synthesis and immune response.
USP15 stabilizes c-Myc to drive sunitinib resistance by suppressing cuproptosis in clear cell renal cell carcinoma.
Ingestion of a human-relevant mixture of environmentally sourced microplastics promotes inflammation and tumorigenesis in the mouse colon.
Multiaction Antimicrobial, Anti-inflammatory, and Prohealing Hydrogel as a Novel Strategy for Preventing Postoperative Pancreatic Fistula.
DNMT3a promotes LUAD cell proliferation and metastasis by activating the HDAC7 signalling pathway.
Mechanism of Curcumin in Inhibiting Proliferation of Head and Neck Squamous Cell Carcinoma: A Network Pharmacology and Cellular Experimental Study.
CELF1 promotes aerobic glycolysis and an aggressive phenotype in ER-positive breast cancer via GLUT1 regulation.
Inhibition of colorectal cancer cell growth by downregulation of M2-PK and reduction of aerobic glycolysis by clove active ingredients.
Glycoprotein M6B suppresses the maintenance of glioma stem cell stemness and proliferation via the integrin β1/β-catenin pathway.
Slow-Release Prostacyclin Agonist-Immersed Sheet Implantation Suppresses Liver Fibrosis via Hippo Signaling Pathway Activation.
The involvement of lncRNA EMSLR in the disulfidptosis and progression of endometrial carcinoma.
Translating m6A-Glycolysis Discovery into Therapy: GOQD-Based Multifunctional Bioactive Scaffolds Rejuvenates Bone Repair in Senescence.
CENP-F promotes HCC cell proliferation mediated by super enhancer reader BRD4.
Inhibition of KAT6A enhances immunotherapy efficacy in colorectal cancer by activating interferon response.
An Anoikis-Based Prognostic Signature Identifies MYC as a Key Regulator of Malignancy and Immunotherapy Resistance in Bladder Cancer.
miR-423-3p inhibits CTNNBIP1/WNT preventing hyperandrogenic polycystic ovary syndrome†.
Comprehensive evaluation of the PCDHB family in gastric cancer: Prognostic significance, immune infiltration, and experimental validation of PCDHB5's oncogenic role.
Role of EZH2 in regulating c-Myc stability through the E3 ubiquitin ligase HUWE1 in heart failure and its mechanisms.
Hsa_circ_0003611 hinders the transformation of mesenchymal stem cells into osteosarcoma cells through suppressing MYC by IGF2BP3 via m(6)A modification.
IGF2BP2 promotes malignant progression of ovarian cancer by regulating protein synthesis through liquid-liquid phase separation.
Empagliflozin alleviates hepatic ischemia-reperfusion injury by inhibiting c-Myc through the JAK1-STAT3 signaling pathway.
ONECUT2-driven activation of ADAMTS14 boosts colorectal cancer stemness via Wnt pathway.
The selenocysteine-containing protein SELENOT maintains dopamine signaling in the midbrain to protect mice from hyperactivity disorder.
Malignant Hepatoblast-Like Cells Sustain Stemness via IGF2-Dependent Cholesterol Accumulation in Hepatoblastoma.
Circaea mollis Siebold & Zucc. Induces Apoptosis in Colorectal Cancer Cells by Inhibiting c-Myc Through the Mediation of RPL5.
The MCM6-c-Myc positive feedback loop mediates bladder cancer progression and cisplatin resistance.
Parabacteroides distasonis promotes liver regeneration by increasing β-hydroxybutyric acid (BHB) production and BHB-driven STAT3 signals.
CTSG restraines the proliferation and metastasis of head and neck squamous cell carcinoma by blocking the JAK2/STAT3 pathway.
PRMT5 Promotes Pancreatic Cancer Tumorigenesis via Positive PRMT5/C-Myc Feedback Loop.
LRRK2 reduces the sensitivity to TKI and PD-1 blockade in ccRCC via activating LPCAT1.
Targeting the MDK/c-Myc complex to overcome temozolomide resistance in glioma.
Effect of COL11A1 on oral squamous cell carcinoma.
MYC promotes group 3 medulloblastoma cell proliferation and alleviates ROS-induced cell death by upregulating transketolase.
A Novel HDAC6 Inhibitor Ameliorates Imiquimod-Induced Psoriasis-Like Inflammation in Mice.
GPX3 promotes cisplatin resistance in TNBC by manipulating ROS-TGFB1-ZEB2.
CCN5 negatively regulates TGF-β-induced endometriosis associated fibrosis through Wnt/β-catenin signaling via Smad3-dependent mechanism.
ALKBH5-Mediated m(6)A Modification of XBP1 Facilitates NSCLC Progression Through the IL-6-JAK-STAT3 Pathway.
Identification of STAT3 and MYC as critical ferroptosis-related biomarkers in septic cardiomyopathy: a bioinformatics and experimental study.
Discovery of N-Trifluoromethylated Noscapines as Novel and Potent Agents for the Treatment of Glioblastoma.
Discovery of Novel Small-Molecule Inhibitors Disrupting the MTDH-SND1 Protein-Protein Interaction.
Two Small Peptides from Buthus martensii Hydrolysates Exhibit Antitumor Activity Through Inhibition of TNF-α-Mediated Signal Transduction Pathways.
ITGA3 promotes pancreatic cancer progression through HIF1α- and c-Myc-driven glycolysis in a collagen I-dependent autocrine manner.
Endosomal trafficking participates in lipid droplet catabolism to maintain lipid homeostasis.
TDP43 is a newly identified substrate for PS1, enhancing the expression of APP following cleavage.
Engineering fibroblast with reprogramming and spheronization for bone defect repair.
Benzo[a]pyrene reduces cellular senescence in ovarian cancer by stabilizing c-Myc independently of DNA damage.
AKR1B10 dictates c-Myc stability to suppress colorectal cancer metastasis via PP2A nitration.
A comprehensive analysis of deubiquitinase USP20 on prognosis and immunity in pan-cancer.
CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells.
GPR168 functions as a tumor suppressor in mouse melanoma by restraining Akt signaling pathway.
DSG2 and c-MYC Interact to Regulate the Expression of ADAM17 and Promote the Development of Cervical Cancer.
SNAP25-induced MYC upregulation promotes high-grade neuroendocrine lung carcinoma progression.
Hypoxia-induced TGFBI maintains glioma stem cells by stabilizing EphA2.
The mechanism of RGS5 regulating gastric cancer mismatch repair protein.
DCAF7 Acts as A Scaffold to Recruit USP10 for G3BP1 Deubiquitylation and Facilitates Chemoresistance and Metastasis in Nasopharyngeal Carcinoma.
Disulfidptosis and ferroptosis related genes define the immune microenvironment and NUBPL serves as a potential biomarker for predicting prognosis and immunotherapy response in bladder cancer.
Xylooligosaccharides alleviate the carbohydrate-enriched diet-induced intestinal barrier dysfunction in carp Megalobrama amblycephala by promoting intestinal development, immunity and gut microbiota.
Acetate utilization promotes hormone therapy resistance in prostate cancer through neuroendocrine differentiation.
MMP-2-triggered, mitochondria-targeted PROTAC-PDT therapy of breast cancer and brain metastases inhibition.
Linc01588 deletion inhibits the malignant biological characteristics of hydroquinone-induced leukemic cells via miR-9-5p/SIRT1.
circCDK13-loaded small extracellular vesicles accelerate healing in preclinical diabetic wound models.
Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages.
Sustained AhR activity programs memory fate of early effector CD8(+) T cells.
The small nucleolar RNA SNORA51 enhances breast cancer stem cell-like properties via the RPL3/NPM1/c-MYC pathway.
The total xanthones extracted from Gentianella acuta alleviates HFpEF by activating the IRE1α/Xbp1s pathway.
Direct contact between tumor cells and platelets initiates a FAK-dependent F3/TGF-β positive feedback loop that promotes tumor progression and EMT in osteosarcoma.
TRIM26 facilitates PRV infection through NDP52-mediated autophagic degradation of MAVS.
The demethylase ALKBH5 mediates ZKSCAN3 expression through the m(6)A modification to activate VEGFA transcription and thus participates in MNNG-induced gastric cancer progression.
PYCR2, induced by c-Myc, promotes the invasiveness and metastasis of breast cancer by activating AKT signalling pathway.
CAFs Homologous Biomimetic Liposome Bearing BET Inhibitor and Pirfenidone Synergistically Promoting Antitumor Efficacy in Pancreatic Ductal Adenocarcinoma.
The temporal association of CapZ with early endosomes regulates endosomal trafficking and viral entry into host cells.
A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer.
Discovery and optimization of novel 4-morpholinothieno[3,2-d]pyrimidine derivatives as potent BET inhibitors for cancer therapy.
HDAC5 deacetylates c-Myc and facilitates cell cycle progression in hepatocellular carcinoma cells.
Pterostilbene suppresses the growth of esophageal squamous cell carcinoma by inhibiting glycolysis and PKM2/STAT3/c-MYC signaling pathway.
GdX inhibits the occurrence and progression of breast cancer by negatively modulating the activity of STAT3.
USP37 promotes diffuse large B-cell lymphoma progression by deubiquitinating and stabilizing c-myc.
Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signaling.
BET inhibition induces GDH1-dependent glutamine metabolic remodeling and vulnerability in liver cancer.
Inhibition of KIF20A enhances the immunotherapeutic effect of hepatocellular carcinoma by enhancing c-Myc ubiquitination.
Lactate drives the ESM1-SCD1 axis to inhibit the antitumor CD8(+) T-cell response by activating the Wnt/β-catenin pathway in ovarian cancer cells and inducing cisplatin resistance.
Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma.
SIRT1 Controls Enteroendocrine Progenitor Cell Proliferation in High-Fat Diet-Fed Mice.
GNPNAT1 is a potential biomarker correlated with immune infiltration and immunotherapy outcome in breast cancer.
UBE2S targets RPL26 for ubiquitination and degradation to promote non-small cell lung cancer progression via regulating c-Myc.
Small-molecule exhibits anti-tumor activity by targeting the RNA m(6)A reader IGF2BP3 in ovarian cancer.
Prognostic and therapeutic implications of iron-related cell death pathways in acute myeloid leukemia.
Nucleolar HEAT Repeat Containing 1 Up-regulated by the Mechanistic Target of Rapamycin Complex 1 Signaling Promotes Hepatocellular Carcinoma Growth by Dominating Ribosome Biogenesis and Proteome Homeostasis.
Enamel defects of Axenfeld-Rieger syndrome and the role of PITX2 in its pathogenesis.
Hsa_circ_0009092/miR-665/NLK signaling axis suppresses colorectal cancer progression via recruiting TAMs in the tumor microenvironment.
ID1 expressing macrophages support cancer cell stemness and limit CD8(+) T cell infiltration in colorectal cancer.
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Upregulated TC1 and downregulated Chibby were correlated with the aberrant β-catenin expression in laryngeal squamous cell carcinoma.
Butyrate prevents the migration and invasion, and aerobic glycolysis in gastric cancer via inhibiting Wnt/β-catenin/c-Myc signaling.
Newcastle Disease Virus Manipulates Mitochondrial MTHFD2-Mediated Nucleotide Metabolism for Virus Replication.
Comprehensive landscape of TGFβ-related signature in osteosarcoma for predicting prognosis, immune characteristics, and therapeutic response.
HSPA5 Promotes Attachment and Internalization of Porcine Epidemic Diarrhea Virus through Interaction with the Spike Protein and the Endo-/Lysosomal Pathway.
Targeting ACYP1-mediated glycolysis reverses lenvatinib resistance and restricts hepatocellular carcinoma progression.
CRIP1 supports the growth and migration of AML-M5 subtype cells by activating Wnt/β-catenin pathway.
Identification of TGF-β-related genes in cardiac hypertrophy and heart failure based on single cell RNA sequencing.
EOAI, a ubiquitin-specific peptidase 5 inhibitor, prevents non-small cell lung cancer progression by inducing DNA damage.
Dynamics and regulation of mitotic chromatin accessibility bookmarking at single-cell resolution.
Combination of chloroquine diphosphate and salidroside induces human liver cell apoptosis via regulation of mitochondrial dysfunction and autophagy.
Palladin promotes cancer stem cell-like properties in lung cancer by activating Wnt/Β-Catenin signaling.
Application of mPEG-CS-cRGD/Bmi-1RNAi-PTX nanoparticles in suppression of laryngeal cancer by targeting cancer stem cells.
Lenvatinib inhibited HCC cell migration and invasion through regulating the transcription and ubiquitination of UHRF1 and DNMT1.
NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2).
Prepubertal exposure to copper oxide nanoparticles induces Leydig cell injury with steroidogenesis disorders in mouse testes.
ASCL2 Affects the Efficacy of Immunotherapy in Colon Adenocarcinoma Based on Single-Cell RNA Sequencing Analysis.
The SKA3-DUSP2 Axis Promotes Gastric Cancer Tumorigenesis and Epithelial-Mesenchymal Transition by Activating the MAPK/ERK Pathway.
Distinct immune and inflammatory response patterns contribute to the identification of poor prognosis and advanced clinical characters in bladder cancer patients.
Loss of exosomal micro-RNA-200b-3p from hypoxia cancer-associated fibroblasts reduces sensitivity to 5-flourouracil in colorectal cancer through targeting high-mobility group box 3.
TFAP2C-Mediated lncRNA PCAT1 Inhibits Ferroptosis in Docetaxel-Resistant Prostate Cancer Through c-Myc/miR-25-3p/SLC7A11 Signaling.
Clinical Impact of the Histopathological Index and Neuroimaging Features Status in Primary Central Nervous System Diffuse Large B-Cell Lymphoma: A Single-Center Retrospective Analysis of 51 Cases.
PGM3 regulates beta-catenin activity to promote colorectal cancer cell progression.
MED16 Promotes Tumour Progression and Tamoxifen Sensitivity by Modulating Autophagy through the mTOR Signalling Pathway in ER-Positive Breast Cancer.
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
Comprehensive comparison between azacytidine and decitabine treatment in an acute myeloid leukemia cell line.
A novel Gboxin analog induces OXPHOS inhibition and mitochondrial dysfunction-mediated apoptosis in diffuse large B-cell lymphoma.
MCM2 promotes the stemness and sorafenib resistance of hepatocellular carcinoma cells via hippo signaling.
Kruppel-like factor 13 inhibits cell proliferation of gastric cancer by inducing autophagic degradation of β-catenin.
KLHL38 facilitates staurosporine-induced apoptosis in HL-1 cells via myocardin degradation.
Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis.
Co-delivery of photosensitizer and diclofenac through sequentially responsive bilirubin nanocarriers for combating hypoxic tumors.
TGF-β1-induced RAP2 regulates invasion in pancreatic cancer.
Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.
INPP5F translocates into cytoplasm and interacts with ASPH to promote tumor growth in hepatocellular carcinoma.
SLCO4A1-AS1 promotes colorectal tumourigenesis by regulating Cdk2/c-Myc signalling.
Kinesin family member 23 exerts a protumor function in breast cancer via stimulation of the Wnt/β-catenin pathway.
The deubiquitinating enzyme USP17 regulates c-Myc levels and controls cell proliferation and glycolysis.
Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.
MxB inhibits long interspersed element type 1 retrotransposition.
The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis.
ALG8 Fuels Stemness Through Glycosylation of the WNT/Beta-Catenin Signaling Pathway in Colon Cancer.
The ubiquitination of CKIP-1 mediated by Src aggravates diabetic renal fibrosis (original article).
Inhibition of cell proliferation by Tas of foamy viruses through cell cycle arrest or apoptosis underlines the different mechanisms of virus-host interactions.
Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1-Wnt/β-catenin-TFE3 feedback loop signalling.
Mitochondrial fragmentation is crucial for c-Myc-driven hepatoblastoma-like liver tumors.
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Epilepsy-Associated UBE3A Deficiency Downregulates Retinoic Acid Signalling Pathway.
Swine Acute Diarrhea Syndrome Coronavirus Nucleocapsid Protein Antagonizes Interferon-β Production via Blocking the Interaction Between TRAF3 and TBK1.
Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1.
Distinguishable Targeting of Non-Small Cell Lung Cancer Using Hyaluronan Functionalized Platinum Nanoclusters and Their Inhibition Behaviors of Proliferation, Invasion, Migration.
Compound heterozygous KCNV2 variants contribute to cone dystrophy with supernormal rod responses in a Chinese family.
E3 ligase TRIM25 ubiquitinates RIP3 to inhibit TNF induced cell necrosis.
DOC-2/DAB2 interactive protein destabilizes c-Myc to impair the growth and self-renewal of colon tumor-repopulating cells.
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
The NF-κB signalling pathway and TM7SF3 contribute to liver fibrosis caused by secreted phospholipase A2 of Clonorchis sinensis.
DEK is highly expressed in breast cancer and is associated with malignant phenotype and progression.
Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops.
CircMTO1 suppresses hepatocellular carcinoma progression via the miR-541-5p/ZIC1 axis by regulating Wnt/β-catenin signaling pathway and epithelial-to-mesenchymal transition.
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
LIMK1 nuclear translocation promotes hepatocellular carcinoma progression by increasing p-ERK nuclear shuttling and by activating c-Myc signalling upon EGF stimulation.
p53-targeted lncRNA ST7-AS1 acts as a tumour suppressor by interacting with PTBP1 to suppress the Wnt/β-catenin signalling pathway in glioma.
PRV-encoded UL13 protein kinase acts as an antagonist of innate immunity by targeting IRF3-signaling pathways.
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
Dong M, Song Z, Lu X, Lu M, Zhong C
Oncology research 2026;34(3):22
Oncology research 2026;34(3):22
A biomimetic arsenic-based nanozyme enhances dual epigenetic regulation to improve the efficacy of immunotherapy for acute myeloid leukaemia.
Chang A, Peng H, Chen Y, Zhang H, Xu X, Zhang K, Yang J, Li W, Wang X, Dong X, Ni J
Biomaterials 2026 Oct;333:124215
Biomaterials 2026 Oct;333:124215
ATP-binding cassette subfamily A member 5 suppresses pancreatic ductal adenocarcinoma progression and chemoresistance by promoting β-catenin ubiquitin-dependent degradation.
Li Z, Ma Z, Chen Y, Yu W, Yu J, Lu J, Zhang Q, Wu Q, Cai Y, Wang Z, Shang C, Hou B, Zhang C, Huang S, Wang L, Zhou Q
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101381
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101381
USP2 promotes metabolic dysfunction-associated steatotic liver disease progression via stabilization of PPARγ.
Luo H, Zhu C, Wang Y, Dai Y, Hao P, Cai H, Bai W, Zhang Z, Wan J, Zhang Y, Sun Y, Zhang Z, Wu Y, Zhai Y, Wu W, Lei H, Xu H, He M, Wu Y
Cell death and differentiation 2026 Mar;33(3):525-538
Cell death and differentiation 2026 Mar;33(3):525-538
HHV-6A Drives Epigenetic Reprogramming via an EZH2-SIRT1 Axis to Sustain Mutant p53 and Reshape Oncogenic Inflammatory Signaling.
Benedetti R, Di Crosta M, Stirparo A, Aron GA, Mardente S, Santarelli R, Gonnella R, Gilardini Montani MS, Cirone M
Viruses 2026 Mar 26;18(4)
Viruses 2026 Mar 26;18(4)
tRF-3005a regulates exon skipping of SPAG4 by interacting with RALY to drive gastric cancer progression.
Cui H, Yuan Y, Yin Y, Gao R, Liu Z, Peng L, Wang J, Wang Z, Song T, Liu J
Cell death discovery 2026 Mar 24;12(1)
Cell death discovery 2026 Mar 24;12(1)
Omics insights into MYBL2-promoted cancer stem-like cells driving ferroptosis resistance in hepatocellular carcinoma.
Chen Y, Li X, Luo C, Lin G, Zhou X, Wen Z, Su H, Meng W, Chen C, Lu J, Luo X, Jiang D, Liu H, Ning Z, Chen Y, Tam PK, Pan X
Journal of advanced research 2026 Mar 19;
Journal of advanced research 2026 Mar 19;
AMBP gene activation promotes cholangiocarcinoma progression through the WNT/β-catenin signaling pathway: Regulatory effect of polysaccharides from Auricularia auricula-judae.
Yang C, Liu Y, Zhang Y, Yang Y, Wu X, Wang Y, Sun F, Zhao Z
Medicine 2026 Mar 13;105(11):e47710
Medicine 2026 Mar 13;105(11):e47710
Design, synthesis, and biological evaluation of selective cytotoxicity-derived Miliusol derivatives inducing profound TNBC regression in vivo.
Cheng X, Chen W, Hao W, Guo Y, Zhang J, Song C, He Z, Wu H, Yao D
Bioorganic & medicinal chemistry 2026 Jul;138:118680
Bioorganic & medicinal chemistry 2026 Jul;138:118680
Reticulon 3 deficiency induces ferroptosis via chaperone-mediated autophagy in ischemia-reperfusion induced acute kidney injury.
Zhang Y, Huang H, Li N, Dong Y, Zhao M, Zhang S, She W, Liu J, Xiang R
Free radical biology & medicine 2026 Jan;242:9-20
Free radical biology & medicine 2026 Jan;242:9-20
NRAV promotes HCC stemness via the m6A-regulated let-7c-5p/LIN28B axis.
Chen Y, Dai S, Zhuang L, Cai W, Chen H, Zhao J, Zhang F, Chen L, Cheng CS
Cancer gene therapy 2026 Feb;33(2):171-185
Cancer gene therapy 2026 Feb;33(2):171-185
MBD3 increased expression by BRD4 and facilitated castration-resistant prostate cancer cell proliferation by inhibiting PTEN.
Pan L, Shen J, Li Z, Xie G, Chen C, Chen X
Discover oncology 2026 Feb 9;17(1)
Discover oncology 2026 Feb 9;17(1)
The GFPT2/O-GlcNAcylation/c-Myc axis promotes bladder cancer progression.
Xie H, Liao T, Tang H, Ban C, Cheng Z, Liao K, Li Y, Wei W, Zhou L, Yi X
Journal of translational medicine 2026 Feb 7;24(1)
Journal of translational medicine 2026 Feb 7;24(1)
FAM64A Potentiates Bladder Carcinoma Tumorigenesis and Metastasis Through PI3K/mTORC2/AKT Pathway Activation.
Zhu T, Liufu C, Yin C, He J, Luo J, Shi B, Wang Y
Cancers 2026 Feb 6;18(3)
Cancers 2026 Feb 6;18(3)
c-Myc/GRPEL1 maintains fatty acid synthesis via FASN to support PDAC cell proliferation.
Wang J, Zhang L, Chen K, Wei F, Li W, Cui C, Chen F, Wei B, Huang T, Fang H, Cui W
Cell death & disease 2026 Feb 5;17(1):205
Cell death & disease 2026 Feb 5;17(1):205
KCTD15 Enhances Stem Cell-Like Properties and Promotes Triple-Negative Breast Cancer Progression Through KLF4/β-Catenin Signaling.
Yao L, Sun W, Xing J, Feng J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71563
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71563
Functional characterization of CASP, a CUX1 isoform, reveals its tumor-promoting role in colorectal cancer via TRIM21-mediated signaling.
Zhou B, Hu W, Dai W, Xu K, Liu L, Zheng S, Wei Q, Chen T
iScience 2026 Feb 20;29(2):114783
iScience 2026 Feb 20;29(2):114783
A pan-cancer single-cell transcriptomic atlas of human bone metastases.
Wang S, Ma F, Wang D, Yu Q, Zheng H, Chen Z, Zhao S, Xu L, Ye Q, Tan Y, Huang W, Sun Z, Wu Z, Cai W, Fang M, Cheng M, Ji Y, Zhang Y, Gu B, Song S, Chen Y, Zhang J, Shao Y, Yan W, Sun Y
Cell reports. Medicine 2026 Feb 17;7(2):102583
Cell reports. Medicine 2026 Feb 17;7(2):102583
RARG promotes gastric cancer progression by activating PMEPA1 transcription and Wnt/β-catenin signalling.
Qin L, Wen F, Guo S, Zhang W, Cai W, Ma R, Liu C, Ren W, Ye H, Jiao Z
Cellular signalling 2026 Aug;144:112552
Cellular signalling 2026 Aug;144:112552
miRNA‑29a inhibits the proliferation of HUVECs by regulating the ITGB1/β‑catenin/c‑Myc pathway.
Sun Q, Chen W, Zhang S, Zhong X, Wu Y, Qian Y, Zhu L, Zhang T, Li W
Molecular medicine reports 2026 Apr;33(4)
Molecular medicine reports 2026 Apr;33(4)
METTL16 promotes MASLD progression through the regulation of lipid synthesis and immune response.
Li G, Wang L, Zhang L, Guo J, Sun Q
Biology direct 2026 Apr 9;21(1)
Biology direct 2026 Apr 9;21(1)
USP15 stabilizes c-Myc to drive sunitinib resistance by suppressing cuproptosis in clear cell renal cell carcinoma.
Chen Y, Huang S, Wang L, Yao Z, Fu S, Hu J, Liu X, Chen Z
Cell reports 2026 Apr 28;45(5):117328
Cell reports 2026 Apr 28;45(5):117328
Ingestion of a human-relevant mixture of environmentally sourced microplastics promotes inflammation and tumorigenesis in the mouse colon.
Djouina M, Pichavant M, Waxin C, Dehaut A, Loison S, Driencourt E, Deborgher A, Balesdent C, Launay D, Dubuquoy L, Duflos G, Body-Malapel M
Environmental pollution (Barking, Essex : 1987) 2026 Apr 15;395:127794
Environmental pollution (Barking, Essex : 1987) 2026 Apr 15;395:127794
Multiaction Antimicrobial, Anti-inflammatory, and Prohealing Hydrogel as a Novel Strategy for Preventing Postoperative Pancreatic Fistula.
Zhou Y, Li L, Chen F, Huang T, Pan M, Huang H
Biomaterials research 2025;29:0194
Biomaterials research 2025;29:0194
DNMT3a promotes LUAD cell proliferation and metastasis by activating the HDAC7 signalling pathway.
Jiang M, Zhou X, Feng Y, Ding P, Li J, Lu D, Qin J, Bai Y, Wang A, Xia C, Wang J, Yan X, Ma Z, Zhang R
International journal of biological sciences 2025;21(4):1585-1602
International journal of biological sciences 2025;21(4):1585-1602
Mechanism of Curcumin in Inhibiting Proliferation of Head and Neck Squamous Cell Carcinoma: A Network Pharmacology and Cellular Experimental Study.
He Y, Liao Y, Fang S, Zhu L, Zhao Z, Chen T, Zhang Z
BioMed research international 2025;2025:4318115
BioMed research international 2025;2025:4318115
CELF1 promotes aerobic glycolysis and an aggressive phenotype in ER-positive breast cancer via GLUT1 regulation.
Li J, Wang N, Bi J, Guo M, Xu B, Huang G
Frontiers in genetics 2025;16:1687066
Frontiers in genetics 2025;16:1687066
Inhibition of colorectal cancer cell growth by downregulation of M2-PK and reduction of aerobic glycolysis by clove active ingredients.
Liu L, Xing G, Guo X, Chen H, Li J, Wang J, Li Y, Liang G, Liu M
Frontiers in pharmacology 2025;16:1552486
Frontiers in pharmacology 2025;16:1552486
Glycoprotein M6B suppresses the maintenance of glioma stem cell stemness and proliferation via the integrin β1/β-catenin pathway.
Chen Y, Fan Y, Run X, Liu M, Jiang S, Miao Z, Tian W
Frontiers in molecular biosciences 2025;12:1731116
Frontiers in molecular biosciences 2025;12:1731116
Slow-Release Prostacyclin Agonist-Immersed Sheet Implantation Suppresses Liver Fibrosis via Hippo Signaling Pathway Activation.
Fujii W, Tomimaru Y, Kobayashi S, Torigata K, Hasegawa K, Harada A, Sasaki K, Hasegawa S, Yamada D, Akita H, Noda T, Takahashi H, Imamura H, Kodama T, Terai S, Sawa Y, Miyagawa S, Doki Y, Eguchi H
Hepatology research : the official journal of the Japan Society of Hepatology 2025 Oct;55(10):1353-1366
Hepatology research : the official journal of the Japan Society of Hepatology 2025 Oct;55(10):1353-1366
The involvement of lncRNA EMSLR in the disulfidptosis and progression of endometrial carcinoma.
Sun Y, Wang R, Li X, Zhou W, Huang H, Zhou Y, Zhu X, Yin Y, Teng Y
Cancer gene therapy 2025 Oct;32(10):1107-1119
Cancer gene therapy 2025 Oct;32(10):1107-1119
Translating m6A-Glycolysis Discovery into Therapy: GOQD-Based Multifunctional Bioactive Scaffolds Rejuvenates Bone Repair in Senescence.
Wang Z, Deng T, Chang H, Li Y, Zhang Y, Jiao X, Gan Y
Small (Weinheim an der Bergstrasse, Germany) 2025 Oct;21(43):e07315
Small (Weinheim an der Bergstrasse, Germany) 2025 Oct;21(43):e07315
CENP-F promotes HCC cell proliferation mediated by super enhancer reader BRD4.
Liu Y, Chen W, Niu Y, Dong X, You J, Yang Z
Discover oncology 2025 Oct 29;16(1):1985
Discover oncology 2025 Oct 29;16(1):1985
Inhibition of KAT6A enhances immunotherapy efficacy in colorectal cancer by activating interferon response.
Han S, Chen Z, Hong C, Dang T, Bai F, Ruan Y, Yang R, Yu X, Li Y, Wang B, Ma Y, Chen F, Xiong R, Zhang Y, Liu C
Cancer letters 2025 Oct 28;631:217946
Cancer letters 2025 Oct 28;631:217946
An Anoikis-Based Prognostic Signature Identifies MYC as a Key Regulator of Malignancy and Immunotherapy Resistance in Bladder Cancer.
Tang Z, Peng J, Pan X, Kong Y, Lin H, Wei S, Zhan Y, Zeng S
Frontiers in bioscience (Landmark edition) 2025 Oct 28;30(10):45386
Frontiers in bioscience (Landmark edition) 2025 Oct 28;30(10):45386
miR-423-3p inhibits CTNNBIP1/WNT preventing hyperandrogenic polycystic ovary syndrome†.
Zhang S, Liu Y, Wang M, Ponikwicka-Tyszko D, Wolczynski S, Chen L, Huang X, Yao B, Rahman NA, Li X
Biology of reproduction 2025 Oct 14;113(4):856-869
Biology of reproduction 2025 Oct 14;113(4):856-869
Comprehensive evaluation of the PCDHB family in gastric cancer: Prognostic significance, immune infiltration, and experimental validation of PCDHB5's oncogenic role.
Zhou J, Zhan J, Zhang H, Liu L, He Y, Le Y, Liu W, Zhou L, Xiang X
International immunopharmacology 2025 Oct 10;163:115318
International immunopharmacology 2025 Oct 10;163:115318
Role of EZH2 in regulating c-Myc stability through the E3 ubiquitin ligase HUWE1 in heart failure and its mechanisms.
Yan L, Xie D, Huang T, Zheng H, Huang J, Chen H, Xie Q, Weng G, Zheng F
Cellular signalling 2025 Nov;135:111968
Cellular signalling 2025 Nov;135:111968
Hsa_circ_0003611 hinders the transformation of mesenchymal stem cells into osteosarcoma cells through suppressing MYC by IGF2BP3 via m(6)A modification.
Zhang F, Cheng F, He Z, Zhao C
Biological research 2025 Nov 29;59(1):2
Biological research 2025 Nov 29;59(1):2
IGF2BP2 promotes malignant progression of ovarian cancer by regulating protein synthesis through liquid-liquid phase separation.
Xiong X, Wang X, Wang Z, Chen F, Shi Y, Chen X, Gong W, Jia X, Xu J
Cell reports 2025 Nov 25;44(11):116511
Cell reports 2025 Nov 25;44(11):116511
Empagliflozin alleviates hepatic ischemia-reperfusion injury by inhibiting c-Myc through the JAK1-STAT3 signaling pathway.
Tulahong A, Xu X, Zhou T, Ruze R, Yuan Z, Qiao P, Jiang T, Aji T, Shao Y
International immunopharmacology 2025 Nov 14;165:115508
International immunopharmacology 2025 Nov 14;165:115508
ONECUT2-driven activation of ADAMTS14 boosts colorectal cancer stemness via Wnt pathway.
Jiang Y, Tan X
Human cell 2025 Nov 12;39(1):7
Human cell 2025 Nov 12;39(1):7
The selenocysteine-containing protein SELENOT maintains dopamine signaling in the midbrain to protect mice from hyperactivity disorder.
Guo Q, Li ZF, Hu DY, Li PJ, Wu KN, Fan HH, Deng J, Wu HM, Zhang X, Zhu JH
The EMBO journal 2025 May;44(10):2906-2927
The EMBO journal 2025 May;44(10):2906-2927
Malignant Hepatoblast-Like Cells Sustain Stemness via IGF2-Dependent Cholesterol Accumulation in Hepatoblastoma.
Ding M, Mao S, Wu H, Fang S, Zhen N, Chen T, Zhu J, Tang X, Wang X, Sun F, Zhu G, Pan Q, Ma J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2407671
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2407671
Circaea mollis Siebold & Zucc. Induces Apoptosis in Colorectal Cancer Cells by Inhibiting c-Myc Through the Mediation of RPL5.
Park SM, Kim N, Park YR, Kim SW, Jung JH, Na YC, Kwon D, Kim H, Jang HJ
International journal of molecular sciences 2025 May 13;26(10)
International journal of molecular sciences 2025 May 13;26(10)
The MCM6-c-Myc positive feedback loop mediates bladder cancer progression and cisplatin resistance.
Wang J, Li X, Zhao L, Fan X, Cao J, Wang S, Li K, Wang H, Zhang Y, Wang H, Xu C, Ding L, Che T, Chen S, Yang L
International journal of biological macromolecules 2025 Mar;296:139777
International journal of biological macromolecules 2025 Mar;296:139777
Parabacteroides distasonis promotes liver regeneration by increasing β-hydroxybutyric acid (BHB) production and BHB-driven STAT3 signals.
Guo M, Jiang X, Ouyang H, Zhang X, Zhang S, Wang P, Bi G, Wu T, Zhou W, Liang F, Yang X, Fan S, Fang JH, Chen P, Bi H
Acta pharmaceutica Sinica. B 2025 Mar;15(3):1430-1446
Acta pharmaceutica Sinica. B 2025 Mar;15(3):1430-1446
CTSG restraines the proliferation and metastasis of head and neck squamous cell carcinoma by blocking the JAK2/STAT3 pathway.
Hua H, Yang X, Meng D, Gan R, Chen N, He L, Wang D, Jiang W, Si D, Wang X, Zhang X, Wei X, Wang Y, Li B, Zhang H, Gao C
Cellular signalling 2025 Mar;127:111562
Cellular signalling 2025 Mar;127:111562
PRMT5 Promotes Pancreatic Cancer Tumorigenesis via Positive PRMT5/C-Myc Feedback Loop.
Yang F, Song P, Xiao Z, Su R, Fang X, Wu Y, Xu X, Wang K
MedComm 2025 Jun;6(6):e70150
MedComm 2025 Jun;6(6):e70150
LRRK2 reduces the sensitivity to TKI and PD-1 blockade in ccRCC via activating LPCAT1.
Hong Y, Li W, Xing Z, Lu M, Tang T, Zhu L, Xiong W, Zhang H, Liu W, Ren S
Oncogene 2025 Jun;44(22):1761-1776
Oncogene 2025 Jun;44(22):1761-1776
Targeting the MDK/c-Myc complex to overcome temozolomide resistance in glioma.
Xi X, Ding X, Wang Q, Liu N, Wang B, Wang G, Zhong W, Lu Y
Clinical and translational medicine 2025 Jun;15(6):e70359
Clinical and translational medicine 2025 Jun;15(6):e70359
Effect of COL11A1 on oral squamous cell carcinoma.
Liu YH, Li D, Zhang HL, Zhang BH, Song WJ, Li TK
Journal of stomatology, oral and maxillofacial surgery 2025 Jun;126(3S):102183
Journal of stomatology, oral and maxillofacial surgery 2025 Jun;126(3S):102183
MYC promotes group 3 medulloblastoma cell proliferation and alleviates ROS-induced cell death by upregulating transketolase.
Wang S, Zhang D, Wang C, Liu Y
Acta neuropathologica communications 2025 Jun 28;13(1):139
Acta neuropathologica communications 2025 Jun 28;13(1):139
A Novel HDAC6 Inhibitor Ameliorates Imiquimod-Induced Psoriasis-Like Inflammation in Mice.
Cao A, Li Y, Feng Y, Wang X, Wei W, Sun H, Quan J
Molecules (Basel, Switzerland) 2025 Jul 31;30(15)
Molecules (Basel, Switzerland) 2025 Jul 31;30(15)
GPX3 promotes cisplatin resistance in TNBC by manipulating ROS-TGFB1-ZEB2.
Hu Q, Chen Q, Yang W, Ren A, Tan J, Huang T
Cell communication and signaling : CCS 2025 Jul 25;23(1):355
Cell communication and signaling : CCS 2025 Jul 25;23(1):355
CCN5 negatively regulates TGF-β-induced endometriosis associated fibrosis through Wnt/β-catenin signaling via Smad3-dependent mechanism.
Liu M, Gong Y, Cai H, Hua R, Li H, Wang Z, Zhou Y, Ma Y, Quan S
Journal of translational medicine 2025 Jul 10;23(1):763
Journal of translational medicine 2025 Jul 10;23(1):763
ALKBH5-Mediated m(6)A Modification of XBP1 Facilitates NSCLC Progression Through the IL-6-JAK-STAT3 Pathway.
Liang H, Zhang C, Hu M, Hu F, Wang S, Wei W, Hu W
Molecular carcinogenesis 2025 Jan;64(1):57-71
Molecular carcinogenesis 2025 Jan;64(1):57-71
Identification of STAT3 and MYC as critical ferroptosis-related biomarkers in septic cardiomyopathy: a bioinformatics and experimental study.
Liu F, Wang Q, Ye H, Du Y, Wang M, Guo Y, He S
Journal of molecular medicine (Berlin, Germany) 2025 Jan;103(1):87-100
Journal of molecular medicine (Berlin, Germany) 2025 Jan;103(1):87-100
Discovery of N-Trifluoromethylated Noscapines as Novel and Potent Agents for the Treatment of Glioblastoma.
Cui G, Fan Y, Yang Y, Ma Y, Deng H, Wang P, Zhu Y, Li J, Wei J, Zhang Y
Journal of medicinal chemistry 2025 Jan 9;68(1):247-260
Journal of medicinal chemistry 2025 Jan 9;68(1):247-260
Discovery of Novel Small-Molecule Inhibitors Disrupting the MTDH-SND1 Protein-Protein Interaction.
Shen H, Ding J, Ji J, Hu L, Min W, Hou Y, Wang D, Chen Y, Wang L, Zhu Y, Wang X, Yang P
Journal of medicinal chemistry 2025 Jan 23;68(2):1844-1862
Journal of medicinal chemistry 2025 Jan 23;68(2):1844-1862
Two Small Peptides from Buthus martensii Hydrolysates Exhibit Antitumor Activity Through Inhibition of TNF-α-Mediated Signal Transduction Pathways.
Zhu M, Zhang S, Tang J, Hou H, Wang L, Lin H, Zhang X, Jin M
Life (Basel, Switzerland) 2025 Jan 15;15(1)
Life (Basel, Switzerland) 2025 Jan 15;15(1)
ITGA3 promotes pancreatic cancer progression through HIF1α- and c-Myc-driven glycolysis in a collagen I-dependent autocrine manner.
Li R, Ji Q, Fu S, Gu J, Liu D, Wang L, Yuan X, Wen Y, Dai C, Li H
Cancer gene therapy 2025 Feb;32(2):240-253
Cancer gene therapy 2025 Feb;32(2):240-253
Endosomal trafficking participates in lipid droplet catabolism to maintain lipid homeostasis.
Peng W, Chen S, Ma J, Wei W, Lin N, Xing J, Guo W, Li H, Zhang L, Chan K, Yen A, Zhu G, Yue J
Nature communications 2025 Feb 24;16(1):1917
Nature communications 2025 Feb 24;16(1):1917
TDP43 is a newly identified substrate for PS1, enhancing the expression of APP following cleavage.
Yin H, Wang Y, Ren Z, Xiao Z, Zhang Y, Wang Y, Guo Z, Chen L, Bao X, Bei Y, Fu X, Zeng L
Cell death discovery 2025 Feb 23;11(1):76
Cell death discovery 2025 Feb 23;11(1):76
Engineering fibroblast with reprogramming and spheronization for bone defect repair.
Li Y, Jiang B, Wu Z, Ma Z, Qiu L, Cui W, Zhao Y, Yan J, Ma D, Wu X, Liang S, Wang S, Zhao Y, Wang M, Hu M
Bioactive materials 2025 Aug;50:414-431
Bioactive materials 2025 Aug;50:414-431
Benzo[a]pyrene reduces cellular senescence in ovarian cancer by stabilizing c-Myc independently of DNA damage.
Fu Z, Chen K, Wang Z, Zheng F, Ni H, Shang Y, Wang Y, Xia D, Wu Y, Qian J
Ecotoxicology and environmental safety 2025 Aug;301:118476
Ecotoxicology and environmental safety 2025 Aug;301:118476
AKR1B10 dictates c-Myc stability to suppress colorectal cancer metastasis via PP2A nitration.
Wu X, Huang S, Gao J, Huang S, Chen L, Zhao Z, Pu R, Ma X, Liu X, He W, Song M
Science advances 2025 Aug 22;11(34):eadv6937
Science advances 2025 Aug 22;11(34):eadv6937
A comprehensive analysis of deubiquitinase USP20 on prognosis and immunity in pan-cancer.
Wang T, Bai Y, Dong Y, Qin J, Zhou X, Wang A, Liu D, Li X, Ma Z, Hu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70499
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70499
CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells.
Xiaoxia F, Rui L, Meiru C, Lu Y, Ying J
Scientific reports 2025 Apr 20;15(1):13647
Scientific reports 2025 Apr 20;15(1):13647
GPR168 functions as a tumor suppressor in mouse melanoma by restraining Akt signaling pathway.
Guo X, Guo Z, Bai P, Guo C, Liu X, Zhu K, Li X, Zhao Y
PloS one 2024;19(5):e0302061
PloS one 2024;19(5):e0302061
DSG2 and c-MYC Interact to Regulate the Expression of ADAM17 and Promote the Development of Cervical Cancer.
Song LM, Yao DJ, Xia L, Wang XM, Liu T, Tang QQ, Zhou J
Cancer management and research 2024;16:703-710
Cancer management and research 2024;16:703-710
SNAP25-induced MYC upregulation promotes high-grade neuroendocrine lung carcinoma progression.
Chen Z, Wang S, Wang J, Wang Y, Qi X, An B, Sun L, Lin L
Frontiers in immunology 2024;15:1411114
Frontiers in immunology 2024;15:1411114
Hypoxia-induced TGFBI maintains glioma stem cells by stabilizing EphA2.
Chen Z, Wang J, Peng P, Liu G, Dong M, Zhang X, Zhang Y, Yang X, Wan L, Xiang W, Zhang S, Zhang B, Wu Q, Yu X, Wan F
Theranostics 2024;14(15):5778-5792
Theranostics 2024;14(15):5778-5792
The mechanism of RGS5 regulating gastric cancer mismatch repair protein.
Yang Z, Zhang R, Liu J, Tian S, Zhang H, Zeng L, Zhang Y, Gao L, Wang M, Shan W, Liu J
Molecular carcinogenesis 2024 Sep;63(9):1750-1767
Molecular carcinogenesis 2024 Sep;63(9):1750-1767
DCAF7 Acts as A Scaffold to Recruit USP10 for G3BP1 Deubiquitylation and Facilitates Chemoresistance and Metastasis in Nasopharyngeal Carcinoma.
Li QJ, Fang XL, Li YQ, Lin JY, Huang CL, He SW, Huang SY, Li JY, Gong S, Liu N, Ma J, Zhao Y, Tang LL
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2403262
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2403262
Disulfidptosis and ferroptosis related genes define the immune microenvironment and NUBPL serves as a potential biomarker for predicting prognosis and immunotherapy response in bladder cancer.
Zhang X, Hong B, Li H, Sun Z, Zhao J, Li M, Wei D, Wang Y, Zhang N
Heliyon 2024 Sep 15;10(17):e37638
Heliyon 2024 Sep 15;10(17):e37638
Xylooligosaccharides alleviate the carbohydrate-enriched diet-induced intestinal barrier dysfunction in carp Megalobrama amblycephala by promoting intestinal development, immunity and gut microbiota.
Chen WL, Dong YZ, Zhang L, Liu ZS, He CF, Liu WB, Li XF
International journal of biological macromolecules 2024 Oct;277(Pt 2):134346
International journal of biological macromolecules 2024 Oct;277(Pt 2):134346
Acetate utilization promotes hormone therapy resistance in prostate cancer through neuroendocrine differentiation.
Gao D, Shen Y, Xu L, Sun Y, Hu H, Xu B, Wang Z, Xu H
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Nov;77:101158
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Nov;77:101158
MMP-2-triggered, mitochondria-targeted PROTAC-PDT therapy of breast cancer and brain metastases inhibition.
Tong F, Wang Y, Xu Y, Zhou Y, He S, Du Y, Yang W, Lei T, Song Y, Gong T, Gao H
Nature communications 2024 Nov 29;15(1):10382
Nature communications 2024 Nov 29;15(1):10382
Linc01588 deletion inhibits the malignant biological characteristics of hydroquinone-induced leukemic cells via miR-9-5p/SIRT1.
Liu Y, Zeng M, Li Z, Lin C, Bao J, Ding W, Wang S, Fan Q, Sun Q, Luo H, Huang J, Chen S, Tang H
Ecotoxicology and environmental safety 2024 May;276:116295
Ecotoxicology and environmental safety 2024 May;276:116295
circCDK13-loaded small extracellular vesicles accelerate healing in preclinical diabetic wound models.
Huang Q, Chu Z, Wang Z, Li Q, Meng S, Lu Y, Ma K, Cui S, Hu W, Zhang W, Wei Q, Qu Y, Li H, Fu X, Zhang C
Nature communications 2024 May 9;15(1):3904
Nature communications 2024 May 9;15(1):3904
Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages.
Dong M, Zhang X, Peng P, Chen Z, Zhang Y, Wan L, Xiang W, Liu G, Guo Y, Xiao Q, Wang B, Guo D, Zhu M, Yu X, Wan F
Cancer letters 2024 May 28;590:216801
Cancer letters 2024 May 28;590:216801
Sustained AhR activity programs memory fate of early effector CD8(+) T cells.
Zhang H, Yang Z, Yuan W, Liu J, Luo X, Zhang Q, Li Y, Chen J, Zhou Y, Lv J, Zhou N, Ma J, Tang K, Huang B
Proceedings of the National Academy of Sciences of the United States of America 2024 Mar 12;121(11):e2317658121
Proceedings of the National Academy of Sciences of the United States of America 2024 Mar 12;121(11):e2317658121
The small nucleolar RNA SNORA51 enhances breast cancer stem cell-like properties via the RPL3/NPM1/c-MYC pathway.
Li S, Jin Z, Song X, Ma J, Peng Z, Yu H, Song J, Zhang Y, Sun X, He M, Yu X, Jin F, Zheng A
Molecular carcinogenesis 2024 Jun;63(6):1117-1132
Molecular carcinogenesis 2024 Jun;63(6):1117-1132
The total xanthones extracted from Gentianella acuta alleviates HFpEF by activating the IRE1α/Xbp1s pathway.
Zhao L, Qin Y, Liu Y, An L, Liu W, Zhang C, Song Q, Dai C, Zhang J, Li A
Journal of cellular and molecular medicine 2024 Jun;28(11):e18466
Journal of cellular and molecular medicine 2024 Jun;28(11):e18466
Direct contact between tumor cells and platelets initiates a FAK-dependent F3/TGF-β positive feedback loop that promotes tumor progression and EMT in osteosarcoma.
Shi Q, Xu J, Chen C, Hu X, Wang B, Zeng F, Ren T, Huang Y, Guo W, Tang X, Ji T
Cancer letters 2024 Jun 1;591:216902
Cancer letters 2024 Jun 1;591:216902
TRIM26 facilitates PRV infection through NDP52-mediated autophagic degradation of MAVS.
Chengyue W, Mengdong W, Xiaoquan W, Yeping C, Hao L, Liumei S, Jianle R, Zhendong Z
Veterinary research 2024 Jul 4;55(1):84
Veterinary research 2024 Jul 4;55(1):84
The demethylase ALKBH5 mediates ZKSCAN3 expression through the m(6)A modification to activate VEGFA transcription and thus participates in MNNG-induced gastric cancer progression.
Wang Q, Huang Y, Jiang M, Tang Y, Wang Q, Bai L, Yu C, Yang X, Ding K, Wang W, Bai J, Chen Y
Journal of hazardous materials 2024 Jul 15;473:134690
Journal of hazardous materials 2024 Jul 15;473:134690
PYCR2, induced by c-Myc, promotes the invasiveness and metastasis of breast cancer by activating AKT signalling pathway.
Wu G, Qin S, Gu K, Zhou Y
The international journal of biochemistry & cell biology 2024 Jan;166:106506
The international journal of biochemistry & cell biology 2024 Jan;166:106506
CAFs Homologous Biomimetic Liposome Bearing BET Inhibitor and Pirfenidone Synergistically Promoting Antitumor Efficacy in Pancreatic Ductal Adenocarcinoma.
Zhang Y, Yu R, Zhao C, Liang J, Zhang Y, Su H, Zhao J, Wu H, Xu S, Zhang Z, Wang L, Zou X, Zhu Y, Zhang S, Lv Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(1):e2305279
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(1):e2305279
The temporal association of CapZ with early endosomes regulates endosomal trafficking and viral entry into host cells.
Zhu H, Wang D, Ye Z, Huang L, Wei W, Chan KM, Zhang R, Zhang L, Yue J
BMC biology 2024 Jan 25;22(1):12
BMC biology 2024 Jan 25;22(1):12
A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer.
Zhan J, Zhou L, Zhang H, Zhou J, He Y, Hu T, Le Y, Lin Y, Wang J, Yu H, Liu Y, Xiang X
Translational oncology 2024 Feb;40:101843
Translational oncology 2024 Feb;40:101843
Discovery and optimization of novel 4-morpholinothieno[3,2-d]pyrimidine derivatives as potent BET inhibitors for cancer therapy.
Ran K, Li Y, Zhang YM, Tang DY, Chen ZZ, Xu ZG, Zhang L, Wang BC, Huang JH
Bioorganic chemistry 2024 Dec;153:107929
Bioorganic chemistry 2024 Dec;153:107929
HDAC5 deacetylates c-Myc and facilitates cell cycle progression in hepatocellular carcinoma cells.
Lin M, Zhou W, Wang Y, Ye J, Jiang T, Han S, Zhu F, Ye M, Fang Z
Cellular signalling 2024 Dec;124:111386
Cellular signalling 2024 Dec;124:111386
Pterostilbene suppresses the growth of esophageal squamous cell carcinoma by inhibiting glycolysis and PKM2/STAT3/c-MYC signaling pathway.
Yang Y, Li S, Shi W, Jin G, Guo D, Li A, Wang B, Lu B, Feng S
International immunopharmacology 2024 Dec 5;142(Pt B):113247
International immunopharmacology 2024 Dec 5;142(Pt B):113247
GdX inhibits the occurrence and progression of breast cancer by negatively modulating the activity of STAT3.
Chen Z, Xu L, Lin S, Huang H, Long Q, Liu J
Cancer biology & therapy 2024 Dec 31;25(1):2420383
Cancer biology & therapy 2024 Dec 31;25(1):2420383
USP37 promotes diffuse large B-cell lymphoma progression by deubiquitinating and stabilizing c-myc.
Li Y, Wang W, Sun L, Huang J, Ma X, Li S, Shi X
Journal of molecular histology 2024 Dec 26;56(1):54
Journal of molecular histology 2024 Dec 26;56(1):54
Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signaling.
Gong K, Zheng Y, Liu Y, Zhang T, Song Y, Chen W, Guo L, Zhou J, Liu W, Fang T, Chen Y, Wang J, Pan F, Shi K
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):3
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):3
BET inhibition induces GDH1-dependent glutamine metabolic remodeling and vulnerability in liver cancer.
Mi W, You J, Li L, Zhu L, Xia X, Yang L, Li F, Xu Y, Bi J, Liu P, Chen L, Li F
Life metabolism 2024 Aug;3(4):loae016
Life metabolism 2024 Aug;3(4):loae016
Inhibition of KIF20A enhances the immunotherapeutic effect of hepatocellular carcinoma by enhancing c-Myc ubiquitination.
Chen S, Zhao L, Liu J, Han P, Jiang W, Liu Y, Hou J, Wang F, Li J
Cancer letters 2024 Aug 28;598:217105
Cancer letters 2024 Aug 28;598:217105
Lactate drives the ESM1-SCD1 axis to inhibit the antitumor CD8(+) T-cell response by activating the Wnt/β-catenin pathway in ovarian cancer cells and inducing cisplatin resistance.
Fan Z, Ye M, Liu D, Zhou W, Zeng T, He S, Li Y
International immunopharmacology 2024 Aug 20;137:112461
International immunopharmacology 2024 Aug 20;137:112461
Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma.
Yang W, Wei Y, Wang T, Xu Y, Jin X, Qian H, Yang S, He S
International journal of molecular medicine 2024 Apr;53(4)
International journal of molecular medicine 2024 Apr;53(4)
SIRT1 Controls Enteroendocrine Progenitor Cell Proliferation in High-Fat Diet-Fed Mice.
Miura M, Igarashi M, Isotani R, Nakagawa-Nagahama Y, Kuranami S, Naruse K, Kadowaki T, Yamauchi T
Cellular and molecular gastroenterology and hepatology 2023;16(6):1040-1057
Cellular and molecular gastroenterology and hepatology 2023;16(6):1040-1057
GNPNAT1 is a potential biomarker correlated with immune infiltration and immunotherapy outcome in breast cancer.
Yuan R, Zhang Y, Wang Y, Chen H, Zhang R, Hu Z, Chai C, Chen T
Frontiers in immunology 2023;14:1152678
Frontiers in immunology 2023;14:1152678
UBE2S targets RPL26 for ubiquitination and degradation to promote non-small cell lung cancer progression via regulating c-Myc.
Gong D, Rao X, Min Z, Liu X, Xin H, Zhou P, Yang L, Li D
American journal of cancer research 2023;13(8):3705-3720
American journal of cancer research 2023;13(8):3705-3720
Small-molecule exhibits anti-tumor activity by targeting the RNA m(6)A reader IGF2BP3 in ovarian cancer.
Shu C, Gu MH, Zeng C, Shao WG, Li HY, Ma XH, Li MX, Cao YY, Zhang MJ, Zhao W, Zhao SL
American journal of cancer research 2023;13(10):4888-4902
American journal of cancer research 2023;13(10):4888-4902
Prognostic and therapeutic implications of iron-related cell death pathways in acute myeloid leukemia.
Li T, Lin T, Zhu J, Zhou M, Fan S, Zhou H, Mu Q, Sheng L, Ouyang G
Frontiers in oncology 2023;13:1222098
Frontiers in oncology 2023;13:1222098
Nucleolar HEAT Repeat Containing 1 Up-regulated by the Mechanistic Target of Rapamycin Complex 1 Signaling Promotes Hepatocellular Carcinoma Growth by Dominating Ribosome Biogenesis and Proteome Homeostasis.
Yang XM, Wang XQ, Hu LP, Feng MX, Zhou YQ, Li DX, Li J, Miao XC, Zhang YL, Yao LL, Nie HZ, Huang S, Xia Q, Zhang XL, Jiang SH, Zhang ZG
Gastroenterology 2023 Sep;165(3):629-646
Gastroenterology 2023 Sep;165(3):629-646
Enamel defects of Axenfeld-Rieger syndrome and the role of PITX2 in its pathogenesis.
Yang Y, Zhu J, Chiba Y, Fukumoto S, Qin M, Wang X
Oral diseases 2023 Nov;29(8):3654-3664
Oral diseases 2023 Nov;29(8):3654-3664
Hsa_circ_0009092/miR-665/NLK signaling axis suppresses colorectal cancer progression via recruiting TAMs in the tumor microenvironment.
Song J, Liu Q, Han L, Song T, Huang S, Zhang X, He Q, Liang C, Zhu S, Xiong B
Journal of experimental & clinical cancer research : CR 2023 Nov 27;42(1):319
Journal of experimental & clinical cancer research : CR 2023 Nov 27;42(1):319
ID1 expressing macrophages support cancer cell stemness and limit CD8(+) T cell infiltration in colorectal cancer.
Shang S, Yang C, Chen F, Xiang RS, Zhang H, Dai SY, Liu J, Lv XX, Zhang C, Liu XT, Zhang Q, Lu SB, Song JW, Yu JJ, Zhou JC, Zhang XW, Cui B, Li PP, Zhu ST, Zhang HZ, Hua F
Nature communications 2023 Nov 23;14(1):7661
Nature communications 2023 Nov 23;14(1):7661
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Cheng Z, Wang H, Yang Z, Li J, Chen X
BMC cancer 2023 Nov 20;23(1):1128
BMC cancer 2023 Nov 20;23(1):1128
Upregulated TC1 and downregulated Chibby were correlated with the aberrant β-catenin expression in laryngeal squamous cell carcinoma.
Ren G, Ma B, Wang J, Xu J, Zhang X, Yin C
Medicine 2023 Nov 17;102(46):e36066
Medicine 2023 Nov 17;102(46):e36066
Butyrate prevents the migration and invasion, and aerobic glycolysis in gastric cancer via inhibiting Wnt/β-catenin/c-Myc signaling.
Liang Y, Rao Z, Du D, Wang Y, Fang T
Drug development research 2023 May;84(3):532-541
Drug development research 2023 May;84(3):532-541
Newcastle Disease Virus Manipulates Mitochondrial MTHFD2-Mediated Nucleotide Metabolism for Virus Replication.
Tang N, Chen P, Zhao C, Liu P, Tan L, Song C, Qiu X, Liao Y, Liu X, Luo T, Sun Y, Ding C
Journal of virology 2023 Mar 30;97(3):e0001623
Journal of virology 2023 Mar 30;97(3):e0001623
Comprehensive landscape of TGFβ-related signature in osteosarcoma for predicting prognosis, immune characteristics, and therapeutic response.
Liu D, Peng Y, Li X, Zhu Z, Mi Z, Zhang Z, Fan H
Journal of bone oncology 2023 Jun;40:100484
Journal of bone oncology 2023 Jun;40:100484
HSPA5 Promotes Attachment and Internalization of Porcine Epidemic Diarrhea Virus through Interaction with the Spike Protein and the Endo-/Lysosomal Pathway.
Zhou C, Liu Y, Wei Q, Chen Y, Yang S, Cheng A, Zhang G
Journal of virology 2023 Jun 29;97(6):e0054923
Journal of virology 2023 Jun 29;97(6):e0054923
Targeting ACYP1-mediated glycolysis reverses lenvatinib resistance and restricts hepatocellular carcinoma progression.
Wang S, Zhou L, Ji N, Sun C, Sun L, Sun J, Du Y, Zhang N, Li Y, Liu W, Lu W
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Jul;69:100976
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Jul;69:100976
CRIP1 supports the growth and migration of AML-M5 subtype cells by activating Wnt/β-catenin pathway.
Deng X, Zeng Y, Qiu X, Zhong M, Xiong X, Luo M, Zhang J, Chen X
Leukemia research 2023 Jul;130:107312
Leukemia research 2023 Jul;130:107312
Identification of TGF-β-related genes in cardiac hypertrophy and heart failure based on single cell RNA sequencing.
Huang K, Wu H, Xu X, Wu L, Li Q, Han L
Aging 2023 Jul 26;15(14):7187-7218
Aging 2023 Jul 26;15(14):7187-7218
EOAI, a ubiquitin-specific peptidase 5 inhibitor, prevents non-small cell lung cancer progression by inducing DNA damage.
Zheng Y, Wang L, Niu X, Guo Y, Zhao J, Li L, Zhao J
BMC cancer 2023 Jan 7;23(1):28
BMC cancer 2023 Jan 7;23(1):28
Dynamics and regulation of mitotic chromatin accessibility bookmarking at single-cell resolution.
Yu Q, Liu X, Fang J, Wu H, Guo C, Zhang W, Liu N, Jiang C, Sha Q, Yuan X, Wang Z, Qu K
Science advances 2023 Jan 25;9(4):eadd2175
Science advances 2023 Jan 25;9(4):eadd2175
Combination of chloroquine diphosphate and salidroside induces human liver cell apoptosis via regulation of mitochondrial dysfunction and autophagy.
Jiang B, Feng L, Yang T, Guo W, Li Y, Wang T, Liu C, Su H
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
Palladin promotes cancer stem cell-like properties in lung cancer by activating Wnt/Β-Catenin signaling.
Shu X, Chen M, Liu SY, Yu L, Sun LX, Sun LC, Ran YL
Cancer medicine 2023 Feb;12(4):4510-4520
Cancer medicine 2023 Feb;12(4):4510-4520
Application of mPEG-CS-cRGD/Bmi-1RNAi-PTX nanoparticles in suppression of laryngeal cancer by targeting cancer stem cells.
Xu X, Zhou T, Wei X, Jiang X, Cao J
Drug delivery 2023 Dec;30(1):2180112
Drug delivery 2023 Dec;30(1):2180112
Lenvatinib inhibited HCC cell migration and invasion through regulating the transcription and ubiquitination of UHRF1 and DNMT1.
Fang T, Jiao Z, You Y, Cao J, Wang C, Liu J, Zhao W
Biochemical pharmacology 2023 Apr;210:115489
Biochemical pharmacology 2023 Apr;210:115489
NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2).
Hao J, Li J, Zhang Z, Yang Y, Zhou Q, Wu T, Chen T, Wu Z, Zhang P, Cui J, Li YP
Autophagy 2023 Apr;19(4):1332-1347
Autophagy 2023 Apr;19(4):1332-1347
Prepubertal exposure to copper oxide nanoparticles induces Leydig cell injury with steroidogenesis disorders in mouse testes.
Zheng X, Chen J, Kang L, Wei Y, Wu Y, Hong Y, Wang X, Li D, Shen L, Long C, Wei G, Wu S
Biochemical and biophysical research communications 2023 Apr 30;654:62-72
Biochemical and biophysical research communications 2023 Apr 30;654:62-72
ASCL2 Affects the Efficacy of Immunotherapy in Colon Adenocarcinoma Based on Single-Cell RNA Sequencing Analysis.
Wu L, Sun S, Qu F, Liu X, Sun M, Pan Y, Zheng Y, Su G
Frontiers in immunology 2022;13:829640
Frontiers in immunology 2022;13:829640
The SKA3-DUSP2 Axis Promotes Gastric Cancer Tumorigenesis and Epithelial-Mesenchymal Transition by Activating the MAPK/ERK Pathway.
Zhang C, Zhao S, Tan Y, Pan S, An W, Chen Q, Wang X, Xu H
Frontiers in pharmacology 2022;13:777612
Frontiers in pharmacology 2022;13:777612
Distinct immune and inflammatory response patterns contribute to the identification of poor prognosis and advanced clinical characters in bladder cancer patients.
Chang Z, Li R, Zhang J, An L, Zhou G, Lei M, Deng J, Yang R, Song Z, Zhong W, Qi D, Duan X, Li S, Sun B, Wu W
Frontiers in immunology 2022;13:1008865
Frontiers in immunology 2022;13:1008865
Loss of exosomal micro-RNA-200b-3p from hypoxia cancer-associated fibroblasts reduces sensitivity to 5-flourouracil in colorectal cancer through targeting high-mobility group box 3.
Yuan H, Chen B, Chai R, Gong W, Wan Z, Zheng B, Hu X, Guo Y, Gao S, Dai Q, Yu P, Tu S
Frontiers in oncology 2022;12:920131
Frontiers in oncology 2022;12:920131
TFAP2C-Mediated lncRNA PCAT1 Inhibits Ferroptosis in Docetaxel-Resistant Prostate Cancer Through c-Myc/miR-25-3p/SLC7A11 Signaling.
Jiang X, Guo S, Xu M, Ma B, Liu R, Xu Y, Zhang Y
Frontiers in oncology 2022;12:862015
Frontiers in oncology 2022;12:862015
Clinical Impact of the Histopathological Index and Neuroimaging Features Status in Primary Central Nervous System Diffuse Large B-Cell Lymphoma: A Single-Center Retrospective Analysis of 51 Cases.
Qi Z, Duan L, Yuan G, Liu J, Li J, Li G, Yu Y, Xu Y, Ma S, Pan Y, Zhang Y
Frontiers in oncology 2022;12:769895
Frontiers in oncology 2022;12:769895
PGM3 regulates beta-catenin activity to promote colorectal cancer cell progression.
Zhang N, Liu S, Xu J, Ning T, Xie S, Min L, Zhu S, Zhang S, Zhu S
Experimental biology and medicine (Maywood, N.J.) 2022 Sep;247(17):1518-1528
Experimental biology and medicine (Maywood, N.J.) 2022 Sep;247(17):1518-1528
MED16 Promotes Tumour Progression and Tamoxifen Sensitivity by Modulating Autophagy through the mTOR Signalling Pathway in ER-Positive Breast Cancer.
Li H, Li K, Shu D, Shen M, Tan Z, Zhang W, Pu D, Tan W, Tang Z, Jin A, Liu S
Life (Basel, Switzerland) 2022 Sep 20;12(10)
Life (Basel, Switzerland) 2022 Sep 20;12(10)
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
Yao H, Ren D, Wang Y, Wu L, Wu Y, Wang W, Li Q, Liu L
Cell death & disease 2022 Sep 2;13(9):761
Cell death & disease 2022 Sep 2;13(9):761
Comprehensive comparison between azacytidine and decitabine treatment in an acute myeloid leukemia cell line.
Aumer T, Gremmelmaier CB, Runtsch LS, Pforr JC, Yeşiltaç GN, Kaiser S, Traube FR
Clinical epigenetics 2022 Sep 11;14(1):113
Clinical epigenetics 2022 Sep 11;14(1):113
A novel Gboxin analog induces OXPHOS inhibition and mitochondrial dysfunction-mediated apoptosis in diffuse large B-cell lymphoma.
Yao S, Yin J, Liu W, Li Y, Huang J, Qi C, Hu Z, Tong Q, Gu L, Zhang Y
Bioorganic chemistry 2022 Oct;127:106019
Bioorganic chemistry 2022 Oct;127:106019
MCM2 promotes the stemness and sorafenib resistance of hepatocellular carcinoma cells via hippo signaling.
Zhou X, Luo J, Xie H, Wei Z, Li T, Liu J, Liao X, Zhu G, Peng T
Cell death discovery 2022 Oct 15;8(1):418
Cell death discovery 2022 Oct 15;8(1):418
Kruppel-like factor 13 inhibits cell proliferation of gastric cancer by inducing autophagic degradation of β-catenin.
Ding Y, Xu Y, Fu Y, Zhang H, Zhao L, Fan X
Discover oncology 2022 Nov 6;13(1):121
Discover oncology 2022 Nov 6;13(1):121
KLHL38 facilitates staurosporine-induced apoptosis in HL-1 cells via myocardin degradation.
Luo Y, Tian L, Liang C, Xu Y
IUBMB life 2022 May;74(5):446-462
IUBMB life 2022 May;74(5):446-462
Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis.
Wang R, Peng C, Song J, Hua Y, Wu Q, Deng L, Cao Y, Zhang J, Zhang L, Wu L, Hou L
International journal of oncology 2022 Mar;60(3)
International journal of oncology 2022 Mar;60(3)
Co-delivery of photosensitizer and diclofenac through sequentially responsive bilirubin nanocarriers for combating hypoxic tumors.
Zhou Y, Tong F, Gu W, He S, Yang X, Li J, Gao YD, Gao H
Acta pharmaceutica Sinica. B 2022 Mar;12(3):1416-1431
Acta pharmaceutica Sinica. B 2022 Mar;12(3):1416-1431
TGF-β1-induced RAP2 regulates invasion in pancreatic cancer.
Jin K, Liu C, Cheng H, Fei Q, Huang Q, Xiao Z, Yu X, Wu W
Acta biochimica et biophysica Sinica 2022 Mar 25;54(3):361-369
Acta biochimica et biophysica Sinica 2022 Mar 25;54(3):361-369
Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.
Ji R, Shi Q, Cao Y, Zhang J, Zhao C, Zhao H, Sayyed Y, Fu L, Li LY
The Journal of biological chemistry 2022 Jun;298(6):102033
The Journal of biological chemistry 2022 Jun;298(6):102033
INPP5F translocates into cytoplasm and interacts with ASPH to promote tumor growth in hepatocellular carcinoma.
Zhou Q, Lin J, Yan Y, Meng S, Liao H, Chen R, He G, Zhu Y, He C, Mao K, Wang J, Zhang J, Zhou Z, Xiao Z
Journal of experimental & clinical cancer research : CR 2022 Jan 7;41(1):13
Journal of experimental & clinical cancer research : CR 2022 Jan 7;41(1):13
SLCO4A1-AS1 promotes colorectal tumourigenesis by regulating Cdk2/c-Myc signalling.
Zhang J, Cui K, Huang L, Yang F, Sun S, Bian Z, Wang X, Li C, Yin Y, Huang S, Zhou L, Fei B, Huang Z
Journal of biomedical science 2022 Jan 17;29(1):4
Journal of biomedical science 2022 Jan 17;29(1):4
Kinesin family member 23 exerts a protumor function in breast cancer via stimulation of the Wnt/β-catenin pathway.
He X, Wang J, Zhou R, Yu S, Jiang J, Zhou Q
Toxicology and applied pharmacology 2022 Jan 15;435:115834
Toxicology and applied pharmacology 2022 Jan 15;435:115834
The deubiquitinating enzyme USP17 regulates c-Myc levels and controls cell proliferation and glycolysis.
Nagasaka M, Inoue Y, Yoshida M, Miyajima C, Morishita D, Tokugawa M, Nakamoto H, Sugano M, Ohoka N, Hayashi H
FEBS letters 2022 Feb;596(4):465-478
FEBS letters 2022 Feb;596(4):465-478
Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.
Tang W, Xue J, Luo L, Wang Y, Cai X, Liu Y, Huang D, Wang X, He T, Lu D, Yang F
Molecular medicine reports 2022 Feb;25(2)
Molecular medicine reports 2022 Feb;25(2)
MxB inhibits long interspersed element type 1 retrotransposition.
Huang Y, Xu F, Mei S, Liu X, Zhao F, Wei L, Fan Z, Hu Y, Wang L, Ai B, Cen S, Liang C, Guo F
PLoS genetics 2022 Feb;18(2):e1010034
PLoS genetics 2022 Feb;18(2):e1010034
The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis.
Zhu Y, Jin L, Shi R, Li J, Wang Y, Zhang L, Liang CZ, Narayana VK, De Souza DP, Thorne RF, Zhang LR, Zhang XD, Wu M
Molecular cell 2022 Feb 3;82(3):542-554.e6
Molecular cell 2022 Feb 3;82(3):542-554.e6
ALG8 Fuels Stemness Through Glycosylation of the WNT/Beta-Catenin Signaling Pathway in Colon Cancer.
Wu X, Wang B, Su Y, He D, Mo H, Zheng M, Meng Z, Ren L, Zhang X, Ren D, Li C
DNA and cell biology 2022 Dec;41(12):1075-1083
DNA and cell biology 2022 Dec;41(12):1075-1083
The ubiquitination of CKIP-1 mediated by Src aggravates diabetic renal fibrosis (original article).
Yang Y, Xiao H, Lin Z, Chen R, Li S, Li C, Sun X, Hei Z, Gong W, Huang H
Biochemical pharmacology 2022 Dec;206:115339
Biochemical pharmacology 2022 Dec;206:115339
Inhibition of cell proliferation by Tas of foamy viruses through cell cycle arrest or apoptosis underlines the different mechanisms of virus-host interactions.
Jie W, Rui-Fen Z, Zhong-Xiang H, Yan W, Wei-Na L, Yong-Ping M, Jing S, Jing-Yi C, Wan-Hong L, Xiao-Hua H, Zhi L, Yan S
Virulence 2022 Dec;13(1):342-354
Virulence 2022 Dec;13(1):342-354
Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1-Wnt/β-catenin-TFE3 feedback loop signalling.
Luo Y, Huang S, Wei J, Zhou H, Wang W, Yang J, Deng Q, Wang H, Fu Z
Clinical and translational medicine 2022 Apr;12(4):e752
Clinical and translational medicine 2022 Apr;12(4):e752
Mitochondrial fragmentation is crucial for c-Myc-driven hepatoblastoma-like liver tumors.
Wang D, Tian J, Yan Z, Yuan Q, Wu D, Liu X, Yang S, Guo S, Wang J, Yang Y, Xing J, An J, Huang Q
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Apr 6;30(4):1645-1660
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Apr 6;30(4):1645-1660
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Gao M, Yang J, Gong H, Lin Y, Liu J
Frontiers in pharmacology 2021;12:760055
Frontiers in pharmacology 2021;12:760055
Epilepsy-Associated UBE3A Deficiency Downregulates Retinoic Acid Signalling Pathway.
Fang M, Li Y, Ren J, Hu R, Gao X, Chen L
Frontiers in genetics 2021;12:681295
Frontiers in genetics 2021;12:681295
Swine Acute Diarrhea Syndrome Coronavirus Nucleocapsid Protein Antagonizes Interferon-β Production via Blocking the Interaction Between TRAF3 and TBK1.
Zhou Z, Sun Y, Xu J, Tang X, Zhou L, Li Q, Lan T, Ma J
Frontiers in immunology 2021;12:573078
Frontiers in immunology 2021;12:573078
Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1.
Wang M, Liu H, Zhang X, Zhao W, Li D, Xu C, Wu Z, Xie F, Li X
Journal of cellular physiology 2021 Sep;236(9):6559-6570
Journal of cellular physiology 2021 Sep;236(9):6559-6570
Distinguishable Targeting of Non-Small Cell Lung Cancer Using Hyaluronan Functionalized Platinum Nanoclusters and Their Inhibition Behaviors of Proliferation, Invasion, Migration.
Liu T, Huang X, Zhao L, Xiao Z, Li Z, Xin Y, Yang S, Guo D, Zhao W, Mi Y, Li H
ChemistryOpen 2021 Sep;10(9):882-888
ChemistryOpen 2021 Sep;10(9):882-888
Compound heterozygous KCNV2 variants contribute to cone dystrophy with supernormal rod responses in a Chinese family.
Liu M, Zhu Y, Huang L, Jiang W, Wu N, Song Y, Lu Y, Ma Y
Molecular genetics & genomic medicine 2021 Oct;9(10):e1795
Molecular genetics & genomic medicine 2021 Oct;9(10):e1795
E3 ligase TRIM25 ubiquitinates RIP3 to inhibit TNF induced cell necrosis.
Mei P, Xie F, Pan J, Wang S, Gao W, Ge R, Gao B, Gao S, Chen X, Wang Y, Wu J, Ding C, Li J
Cell death and differentiation 2021 Oct;28(10):2888-2899
Cell death and differentiation 2021 Oct;28(10):2888-2899
DOC-2/DAB2 interactive protein destabilizes c-Myc to impair the growth and self-renewal of colon tumor-repopulating cells.
Li H, Zhou Y, Wang M, Wang H, Zhang Y, Peng R, Zhang R, Zhang M, Zhang M, Qiu P, Liu L, Zhao Q, Liu J
Cancer science 2021 Nov;112(11):4593-4603
Cancer science 2021 Nov;112(11):4593-4603
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
Wang D, Ye Z, Wei W, Yu J, Huang L, Zhang H, Yue J
eLife 2021 Nov 19;10
eLife 2021 Nov 19;10
The NF-κB signalling pathway and TM7SF3 contribute to liver fibrosis caused by secreted phospholipase A2 of Clonorchis sinensis.
Wu YJ, He Q, Shang M, Yin YX, Li Y, Du X, Li XR
Parasites & vectors 2021 Mar 10;14(1):152
Parasites & vectors 2021 Mar 10;14(1):152
DEK is highly expressed in breast cancer and is associated with malignant phenotype and progression.
Yang MQ, Bai LL, Wang Z, Lei L, Zheng YW, Li ZH, Huang WJ, Liu CC, Xu HT
Oncology letters 2021 Jun;21(6):440
Oncology letters 2021 Jun;21(6):440
Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops.
Urrutia-Irazabal I, Ault JR, Sobott F, Savery NJ, Dillingham MS
eLife 2021 Jul 19;10
eLife 2021 Jul 19;10
CircMTO1 suppresses hepatocellular carcinoma progression via the miR-541-5p/ZIC1 axis by regulating Wnt/β-catenin signaling pathway and epithelial-to-mesenchymal transition.
Li D, Zhang J, Yang J, Wang J, Zhang R, Li J, Zhang R
Cell death & disease 2021 Dec 20;13(1):12
Cell death & disease 2021 Dec 20;13(1):12
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
Guan Y, Li Y, Yang QB, Yu J, Qiao H
Annals of translational medicine 2021 Apr;9(8):664
Annals of translational medicine 2021 Apr;9(8):664
LIMK1 nuclear translocation promotes hepatocellular carcinoma progression by increasing p-ERK nuclear shuttling and by activating c-Myc signalling upon EGF stimulation.
Pan Z, Liu C, Zhi Y, Xie Z, Wu L, Jiang M, Zhang Y, Zhou R, Zhao L
Oncogene 2021 Apr;40(14):2581-2595
Oncogene 2021 Apr;40(14):2581-2595
p53-targeted lncRNA ST7-AS1 acts as a tumour suppressor by interacting with PTBP1 to suppress the Wnt/β-catenin signalling pathway in glioma.
Sheng J, He X, Yu W, Chen Y, Long Y, Wang K, Zhu S, Liu Q
Cancer letters 2021 Apr 10;503:54-68
Cancer letters 2021 Apr 10;503:54-68
PRV-encoded UL13 protein kinase acts as an antagonist of innate immunity by targeting IRF3-signaling pathways.
Lv L, Cao M, Bai J, Jin L, Wang X, Gao Y, Liu X, Jiang P
Veterinary microbiology 2020 Nov;250:108860
Veterinary microbiology 2020 Nov;250:108860
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
Gong C, Hu X, Xu Y, Yang J, Zong L, Wang C, Zhu J, Li Z, Lu D
Anti-cancer drugs 2020 Feb;31(2):141-149
Anti-cancer drugs 2020 Feb;31(2):141-149
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