Antibody data
- Antibody Data
- Antigen structure
- References [82]
- Comments [0]
- Validations [0]
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- Product number
- 67447-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- c-Myc antibody
- Antibody type
- Monoclonal
- Description
- c-MYC antibody (Cat. #67447-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: FC, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3D9C12
- Vial size
- 20ul, 150ul
Submitted references Linc01588 deletion inhibits the malignant biological characteristics of hydroquinone-induced leukemic cells via miR-9-5p/SIRT1.
Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages.
Sustained AhR activity programs memory fate of early effector CD8(+) T cells.
The small nucleolar RNA SNORA51 enhances breast cancer stem cell-like properties via the RPL3/NPM1/c-MYC pathway.
The total xanthones extracted from Gentianella acuta alleviates HFpEF by activating the IRE1α/Xbp1s pathway.
Direct contact between tumor cells and platelets initiates a FAK-dependent F3/TGF-β positive feedback loop that promotes tumor progression and EMT in osteosarcoma.
The demethylase ALKBH5 mediates ZKSCAN3 expression through the m(6)A modification to activate VEGFA transcription and thus participates in MNNG-induced gastric cancer progression.
PYCR2, induced by c-Myc, promotes the invasiveness and metastasis of breast cancer by activating AKT signalling pathway.
CAFs Homologous Biomimetic Liposome Bearing BET Inhibitor and Pirfenidone Synergistically Promoting Antitumor Efficacy in Pancreatic Ductal Adenocarcinoma.
The temporal association of CapZ with early endosomes regulates endosomal trafficking and viral entry into host cells.
A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer.
Lactate drives the ESM1-SCD1 axis to inhibit the antitumor CD8(+) T-cell response by activating the Wnt/β-catenin pathway in ovarian cancer cells and inducing cisplatin resistance.
Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma.
SIRT1 Controls Enteroendocrine Progenitor Cell Proliferation in High-Fat Diet-Fed Mice.
GNPNAT1 is a potential biomarker correlated with immune infiltration and immunotherapy outcome in breast cancer.
UBE2S targets RPL26 for ubiquitination and degradation to promote non-small cell lung cancer progression via regulating c-Myc.
Small-molecule exhibits anti-tumor activity by targeting the RNA m(6)A reader IGF2BP3 in ovarian cancer.
Prognostic and therapeutic implications of iron-related cell death pathways in acute myeloid leukemia.
Nucleolar HEAT Repeat Containing 1 Up-regulated by the Mechanistic Target of Rapamycin Complex 1 Signaling Promotes Hepatocellular Carcinoma Growth by Dominating Ribosome Biogenesis and Proteome Homeostasis.
Enamel defects of Axenfeld-Rieger syndrome and the role of PITX2 in its pathogenesis.
Hsa_circ_0009092/miR-665/NLK signaling axis suppresses colorectal cancer progression via recruiting TAMs in the tumor microenvironment.
ID1 expressing macrophages support cancer cell stemness and limit CD8(+) T cell infiltration in colorectal cancer.
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Upregulated TC1 and downregulated Chibby were correlated with the aberrant β-catenin expression in laryngeal squamous cell carcinoma.
Butyrate prevents the migration and invasion, and aerobic glycolysis in gastric cancer via inhibiting Wnt/β-catenin/c-Myc signaling.
Newcastle Disease Virus Manipulates Mitochondrial MTHFD2-Mediated Nucleotide Metabolism for Virus Replication.
Comprehensive landscape of TGFβ-related signature in osteosarcoma for predicting prognosis, immune characteristics, and therapeutic response.
HSPA5 Promotes Attachment and Internalization of Porcine Epidemic Diarrhea Virus through Interaction with the Spike Protein and the Endo-/Lysosomal Pathway.
Targeting ACYP1-mediated glycolysis reverses lenvatinib resistance and restricts hepatocellular carcinoma progression.
CRIP1 supports the growth and migration of AML-M5 subtype cells by activating Wnt/β-catenin pathway.
Identification of TGF-β-related genes in cardiac hypertrophy and heart failure based on single cell RNA sequencing.
Dynamics and regulation of mitotic chromatin accessibility bookmarking at single-cell resolution.
Combination of chloroquine diphosphate and salidroside induces human liver cell apoptosis via regulation of mitochondrial dysfunction and autophagy.
Palladin promotes cancer stem cell-like properties in lung cancer by activating Wnt/Β-Catenin signaling.
Application of mPEG-CS-cRGD/Bmi-1RNAi-PTX nanoparticles in suppression of laryngeal cancer by targeting cancer stem cells.
Lenvatinib inhibited HCC cell migration and invasion through regulating the transcription and ubiquitination of UHRF1 and DNMT1.
NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2).
Prepubertal exposure to copper oxide nanoparticles induces Leydig cell injury with steroidogenesis disorders in mouse testes.
ASCL2 Affects the Efficacy of Immunotherapy in Colon Adenocarcinoma Based on Single-Cell RNA Sequencing Analysis.
The SKA3-DUSP2 Axis Promotes Gastric Cancer Tumorigenesis and Epithelial-Mesenchymal Transition by Activating the MAPK/ERK Pathway.
Distinct immune and inflammatory response patterns contribute to the identification of poor prognosis and advanced clinical characters in bladder cancer patients.
Loss of exosomal micro-RNA-200b-3p from hypoxia cancer-associated fibroblasts reduces sensitivity to 5-flourouracil in colorectal cancer through targeting high-mobility group box 3.
TFAP2C-Mediated lncRNA PCAT1 Inhibits Ferroptosis in Docetaxel-Resistant Prostate Cancer Through c-Myc/miR-25-3p/SLC7A11 Signaling.
Clinical Impact of the Histopathological Index and Neuroimaging Features Status in Primary Central Nervous System Diffuse Large B-Cell Lymphoma: A Single-Center Retrospective Analysis of 51 Cases.
PGM3 regulates beta-catenin activity to promote colorectal cancer cell progression.
MED16 Promotes Tumour Progression and Tamoxifen Sensitivity by Modulating Autophagy through the mTOR Signalling Pathway in ER-Positive Breast Cancer.
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
Comprehensive comparison between azacytidine and decitabine treatment in an acute myeloid leukemia cell line.
A novel Gboxin analog induces OXPHOS inhibition and mitochondrial dysfunction-mediated apoptosis in diffuse large B-cell lymphoma.
KLHL38 facilitates staurosporine-induced apoptosis in HL-1 cells via myocardin degradation.
Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis.
Co-delivery of photosensitizer and diclofenac through sequentially responsive bilirubin nanocarriers for combating hypoxic tumors.
TGF-β1-induced RAP2 regulates invasion in pancreatic cancer.
Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.
INPP5F translocates into cytoplasm and interacts with ASPH to promote tumor growth in hepatocellular carcinoma.
SLCO4A1-AS1 promotes colorectal tumourigenesis by regulating Cdk2/c-Myc signalling.
Kinesin family member 23 exerts a protumor function in breast cancer via stimulation of the Wnt/β-catenin pathway.
Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.
MxB inhibits long interspersed element type 1 retrotransposition.
The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis.
ALG8 Fuels Stemness Through Glycosylation of the WNT/Beta-Catenin Signaling Pathway in Colon Cancer.
The ubiquitination of CKIP-1 mediated by Src aggravates diabetic renal fibrosis (original article).
Inhibition of cell proliferation by Tas of foamy viruses through cell cycle arrest or apoptosis underlines the different mechanisms of virus-host interactions.
Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1-Wnt/β-catenin-TFE3 feedback loop signalling.
Mitochondrial fragmentation is crucial for c-Myc-driven hepatoblastoma-like liver tumors.
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Epilepsy-Associated UBE3A Deficiency Downregulates Retinoic Acid Signalling Pathway.
Swine Acute Diarrhea Syndrome Coronavirus Nucleocapsid Protein Antagonizes Interferon-β Production via Blocking the Interaction Between TRAF3 and TBK1.
Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1.
Distinguishable Targeting of Non-Small Cell Lung Cancer Using Hyaluronan Functionalized Platinum Nanoclusters and Their Inhibition Behaviors of Proliferation, Invasion, Migration.
Compound heterozygous KCNV2 variants contribute to cone dystrophy with supernormal rod responses in a Chinese family.
E3 ligase TRIM25 ubiquitinates RIP3 to inhibit TNF induced cell necrosis.
DOC-2/DAB2 interactive protein destabilizes c-Myc to impair the growth and self-renewal of colon tumor-repopulating cells.
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
The NF-κB signalling pathway and TM7SF3 contribute to liver fibrosis caused by secreted phospholipase A2 of Clonorchis sinensis.
DEK is highly expressed in breast cancer and is associated with malignant phenotype and progression.
CircMTO1 suppresses hepatocellular carcinoma progression via the miR-541-5p/ZIC1 axis by regulating Wnt/β-catenin signaling pathway and epithelial-to-mesenchymal transition.
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
LIMK1 nuclear translocation promotes hepatocellular carcinoma progression by increasing p-ERK nuclear shuttling and by activating c-Myc signalling upon EGF stimulation.
p53-targeted lncRNA ST7-AS1 acts as a tumour suppressor by interacting with PTBP1 to suppress the Wnt/β-catenin signalling pathway in glioma.
PRV-encoded UL13 protein kinase acts as an antagonist of innate immunity by targeting IRF3-signaling pathways.
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
Liu Y, Zeng M, Li Z, Lin C, Bao J, Ding W, Wang S, Fan Q, Sun Q, Luo H, Huang J, Chen S, Tang H
Ecotoxicology and environmental safety 2024 May;276:116295
Ecotoxicology and environmental safety 2024 May;276:116295
Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages.
Dong M, Zhang X, Peng P, Chen Z, Zhang Y, Wan L, Xiang W, Liu G, Guo Y, Xiao Q, Wang B, Guo D, Zhu M, Yu X, Wan F
Cancer letters 2024 May 28;590:216801
Cancer letters 2024 May 28;590:216801
Sustained AhR activity programs memory fate of early effector CD8(+) T cells.
Zhang H, Yang Z, Yuan W, Liu J, Luo X, Zhang Q, Li Y, Chen J, Zhou Y, Lv J, Zhou N, Ma J, Tang K, Huang B
Proceedings of the National Academy of Sciences of the United States of America 2024 Mar 12;121(11):e2317658121
Proceedings of the National Academy of Sciences of the United States of America 2024 Mar 12;121(11):e2317658121
The small nucleolar RNA SNORA51 enhances breast cancer stem cell-like properties via the RPL3/NPM1/c-MYC pathway.
Li S, Jin Z, Song X, Ma J, Peng Z, Yu H, Song J, Zhang Y, Sun X, He M, Yu X, Jin F, Zheng A
Molecular carcinogenesis 2024 Jun;63(6):1117-1132
Molecular carcinogenesis 2024 Jun;63(6):1117-1132
The total xanthones extracted from Gentianella acuta alleviates HFpEF by activating the IRE1α/Xbp1s pathway.
Zhao L, Qin Y, Liu Y, An L, Liu W, Zhang C, Song Q, Dai C, Zhang J, Li A
Journal of cellular and molecular medicine 2024 Jun;28(11):e18466
Journal of cellular and molecular medicine 2024 Jun;28(11):e18466
Direct contact between tumor cells and platelets initiates a FAK-dependent F3/TGF-β positive feedback loop that promotes tumor progression and EMT in osteosarcoma.
Shi Q, Xu J, Chen C, Hu X, Wang B, Zeng F, Ren T, Huang Y, Guo W, Tang X, Ji T
Cancer letters 2024 Jun 1;591:216902
Cancer letters 2024 Jun 1;591:216902
The demethylase ALKBH5 mediates ZKSCAN3 expression through the m(6)A modification to activate VEGFA transcription and thus participates in MNNG-induced gastric cancer progression.
Wang Q, Huang Y, Jiang M, Tang Y, Wang Q, Bai L, Yu C, Yang X, Ding K, Wang W, Bai J, Chen Y
Journal of hazardous materials 2024 Jul 15;473:134690
Journal of hazardous materials 2024 Jul 15;473:134690
PYCR2, induced by c-Myc, promotes the invasiveness and metastasis of breast cancer by activating AKT signalling pathway.
Wu G, Qin S, Gu K, Zhou Y
The international journal of biochemistry & cell biology 2024 Jan;166:106506
The international journal of biochemistry & cell biology 2024 Jan;166:106506
CAFs Homologous Biomimetic Liposome Bearing BET Inhibitor and Pirfenidone Synergistically Promoting Antitumor Efficacy in Pancreatic Ductal Adenocarcinoma.
Zhang Y, Yu R, Zhao C, Liang J, Zhang Y, Su H, Zhao J, Wu H, Xu S, Zhang Z, Wang L, Zou X, Zhu Y, Zhang S, Lv Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(1):e2305279
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(1):e2305279
The temporal association of CapZ with early endosomes regulates endosomal trafficking and viral entry into host cells.
Zhu H, Wang D, Ye Z, Huang L, Wei W, Chan KM, Zhang R, Zhang L, Yue J
BMC biology 2024 Jan 25;22(1):12
BMC biology 2024 Jan 25;22(1):12
A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer.
Zhan J, Zhou L, Zhang H, Zhou J, He Y, Hu T, Le Y, Lin Y, Wang J, Yu H, Liu Y, Xiang X
Translational oncology 2024 Feb;40:101843
Translational oncology 2024 Feb;40:101843
Lactate drives the ESM1-SCD1 axis to inhibit the antitumor CD8(+) T-cell response by activating the Wnt/β-catenin pathway in ovarian cancer cells and inducing cisplatin resistance.
Fan Z, Ye M, Liu D, Zhou W, Zeng T, He S, Li Y
International immunopharmacology 2024 Aug 20;137:112461
International immunopharmacology 2024 Aug 20;137:112461
Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma.
Yang W, Wei Y, Wang T, Xu Y, Jin X, Qian H, Yang S, He S
International journal of molecular medicine 2024 Apr;53(4)
International journal of molecular medicine 2024 Apr;53(4)
SIRT1 Controls Enteroendocrine Progenitor Cell Proliferation in High-Fat Diet-Fed Mice.
Miura M, Igarashi M, Isotani R, Nakagawa-Nagahama Y, Kuranami S, Naruse K, Kadowaki T, Yamauchi T
Cellular and molecular gastroenterology and hepatology 2023;16(6):1040-1057
Cellular and molecular gastroenterology and hepatology 2023;16(6):1040-1057
GNPNAT1 is a potential biomarker correlated with immune infiltration and immunotherapy outcome in breast cancer.
Yuan R, Zhang Y, Wang Y, Chen H, Zhang R, Hu Z, Chai C, Chen T
Frontiers in immunology 2023;14:1152678
Frontiers in immunology 2023;14:1152678
UBE2S targets RPL26 for ubiquitination and degradation to promote non-small cell lung cancer progression via regulating c-Myc.
Gong D, Rao X, Min Z, Liu X, Xin H, Zhou P, Yang L, Li D
American journal of cancer research 2023;13(8):3705-3720
American journal of cancer research 2023;13(8):3705-3720
Small-molecule exhibits anti-tumor activity by targeting the RNA m(6)A reader IGF2BP3 in ovarian cancer.
Shu C, Gu MH, Zeng C, Shao WG, Li HY, Ma XH, Li MX, Cao YY, Zhang MJ, Zhao W, Zhao SL
American journal of cancer research 2023;13(10):4888-4902
American journal of cancer research 2023;13(10):4888-4902
Prognostic and therapeutic implications of iron-related cell death pathways in acute myeloid leukemia.
Li T, Lin T, Zhu J, Zhou M, Fan S, Zhou H, Mu Q, Sheng L, Ouyang G
Frontiers in oncology 2023;13:1222098
Frontiers in oncology 2023;13:1222098
Nucleolar HEAT Repeat Containing 1 Up-regulated by the Mechanistic Target of Rapamycin Complex 1 Signaling Promotes Hepatocellular Carcinoma Growth by Dominating Ribosome Biogenesis and Proteome Homeostasis.
Yang XM, Wang XQ, Hu LP, Feng MX, Zhou YQ, Li DX, Li J, Miao XC, Zhang YL, Yao LL, Nie HZ, Huang S, Xia Q, Zhang XL, Jiang SH, Zhang ZG
Gastroenterology 2023 Sep;165(3):629-646
Gastroenterology 2023 Sep;165(3):629-646
Enamel defects of Axenfeld-Rieger syndrome and the role of PITX2 in its pathogenesis.
Yang Y, Zhu J, Chiba Y, Fukumoto S, Qin M, Wang X
Oral diseases 2023 Nov;29(8):3654-3664
Oral diseases 2023 Nov;29(8):3654-3664
Hsa_circ_0009092/miR-665/NLK signaling axis suppresses colorectal cancer progression via recruiting TAMs in the tumor microenvironment.
Song J, Liu Q, Han L, Song T, Huang S, Zhang X, He Q, Liang C, Zhu S, Xiong B
Journal of experimental & clinical cancer research : CR 2023 Nov 27;42(1):319
Journal of experimental & clinical cancer research : CR 2023 Nov 27;42(1):319
ID1 expressing macrophages support cancer cell stemness and limit CD8(+) T cell infiltration in colorectal cancer.
Shang S, Yang C, Chen F, Xiang RS, Zhang H, Dai SY, Liu J, Lv XX, Zhang C, Liu XT, Zhang Q, Lu SB, Song JW, Yu JJ, Zhou JC, Zhang XW, Cui B, Li PP, Zhu ST, Zhang HZ, Hua F
Nature communications 2023 Nov 23;14(1):7661
Nature communications 2023 Nov 23;14(1):7661
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Cheng Z, Wang H, Yang Z, Li J, Chen X
BMC cancer 2023 Nov 20;23(1):1128
BMC cancer 2023 Nov 20;23(1):1128
Upregulated TC1 and downregulated Chibby were correlated with the aberrant β-catenin expression in laryngeal squamous cell carcinoma.
Ren G, Ma B, Wang J, Xu J, Zhang X, Yin C
Medicine 2023 Nov 17;102(46):e36066
Medicine 2023 Nov 17;102(46):e36066
Butyrate prevents the migration and invasion, and aerobic glycolysis in gastric cancer via inhibiting Wnt/β-catenin/c-Myc signaling.
Liang Y, Rao Z, Du D, Wang Y, Fang T
Drug development research 2023 May;84(3):532-541
Drug development research 2023 May;84(3):532-541
Newcastle Disease Virus Manipulates Mitochondrial MTHFD2-Mediated Nucleotide Metabolism for Virus Replication.
Tang N, Chen P, Zhao C, Liu P, Tan L, Song C, Qiu X, Liao Y, Liu X, Luo T, Sun Y, Ding C
Journal of virology 2023 Mar 30;97(3):e0001623
Journal of virology 2023 Mar 30;97(3):e0001623
Comprehensive landscape of TGFβ-related signature in osteosarcoma for predicting prognosis, immune characteristics, and therapeutic response.
Liu D, Peng Y, Li X, Zhu Z, Mi Z, Zhang Z, Fan H
Journal of bone oncology 2023 Jun;40:100484
Journal of bone oncology 2023 Jun;40:100484
HSPA5 Promotes Attachment and Internalization of Porcine Epidemic Diarrhea Virus through Interaction with the Spike Protein and the Endo-/Lysosomal Pathway.
Zhou C, Liu Y, Wei Q, Chen Y, Yang S, Cheng A, Zhang G
Journal of virology 2023 Jun 29;97(6):e0054923
Journal of virology 2023 Jun 29;97(6):e0054923
Targeting ACYP1-mediated glycolysis reverses lenvatinib resistance and restricts hepatocellular carcinoma progression.
Wang S, Zhou L, Ji N, Sun C, Sun L, Sun J, Du Y, Zhang N, Li Y, Liu W, Lu W
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Jul;69:100976
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Jul;69:100976
CRIP1 supports the growth and migration of AML-M5 subtype cells by activating Wnt/β-catenin pathway.
Deng X, Zeng Y, Qiu X, Zhong M, Xiong X, Luo M, Zhang J, Chen X
Leukemia research 2023 Jul;130:107312
Leukemia research 2023 Jul;130:107312
Identification of TGF-β-related genes in cardiac hypertrophy and heart failure based on single cell RNA sequencing.
Huang K, Wu H, Xu X, Wu L, Li Q, Han L
Aging 2023 Jul 26;15(14):7187-7218
Aging 2023 Jul 26;15(14):7187-7218
Dynamics and regulation of mitotic chromatin accessibility bookmarking at single-cell resolution.
Yu Q, Liu X, Fang J, Wu H, Guo C, Zhang W, Liu N, Jiang C, Sha Q, Yuan X, Wang Z, Qu K
Science advances 2023 Jan 25;9(4):eadd2175
Science advances 2023 Jan 25;9(4):eadd2175
Combination of chloroquine diphosphate and salidroside induces human liver cell apoptosis via regulation of mitochondrial dysfunction and autophagy.
Jiang B, Feng L, Yang T, Guo W, Li Y, Wang T, Liu C, Su H
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
Palladin promotes cancer stem cell-like properties in lung cancer by activating Wnt/Β-Catenin signaling.
Shu X, Chen M, Liu SY, Yu L, Sun LX, Sun LC, Ran YL
Cancer medicine 2023 Feb;12(4):4510-4520
Cancer medicine 2023 Feb;12(4):4510-4520
Application of mPEG-CS-cRGD/Bmi-1RNAi-PTX nanoparticles in suppression of laryngeal cancer by targeting cancer stem cells.
Xu X, Zhou T, Wei X, Jiang X, Cao J
Drug delivery 2023 Dec;30(1):2180112
Drug delivery 2023 Dec;30(1):2180112
Lenvatinib inhibited HCC cell migration and invasion through regulating the transcription and ubiquitination of UHRF1 and DNMT1.
Fang T, Jiao Z, You Y, Cao J, Wang C, Liu J, Zhao W
Biochemical pharmacology 2023 Apr;210:115489
Biochemical pharmacology 2023 Apr;210:115489
NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2).
Hao J, Li J, Zhang Z, Yang Y, Zhou Q, Wu T, Chen T, Wu Z, Zhang P, Cui J, Li YP
Autophagy 2023 Apr;19(4):1332-1347
Autophagy 2023 Apr;19(4):1332-1347
Prepubertal exposure to copper oxide nanoparticles induces Leydig cell injury with steroidogenesis disorders in mouse testes.
Zheng X, Chen J, Kang L, Wei Y, Wu Y, Hong Y, Wang X, Li D, Shen L, Long C, Wei G, Wu S
Biochemical and biophysical research communications 2023 Apr 30;654:62-72
Biochemical and biophysical research communications 2023 Apr 30;654:62-72
ASCL2 Affects the Efficacy of Immunotherapy in Colon Adenocarcinoma Based on Single-Cell RNA Sequencing Analysis.
Wu L, Sun S, Qu F, Liu X, Sun M, Pan Y, Zheng Y, Su G
Frontiers in immunology 2022;13:829640
Frontiers in immunology 2022;13:829640
The SKA3-DUSP2 Axis Promotes Gastric Cancer Tumorigenesis and Epithelial-Mesenchymal Transition by Activating the MAPK/ERK Pathway.
Zhang C, Zhao S, Tan Y, Pan S, An W, Chen Q, Wang X, Xu H
Frontiers in pharmacology 2022;13:777612
Frontiers in pharmacology 2022;13:777612
Distinct immune and inflammatory response patterns contribute to the identification of poor prognosis and advanced clinical characters in bladder cancer patients.
Chang Z, Li R, Zhang J, An L, Zhou G, Lei M, Deng J, Yang R, Song Z, Zhong W, Qi D, Duan X, Li S, Sun B, Wu W
Frontiers in immunology 2022;13:1008865
Frontiers in immunology 2022;13:1008865
Loss of exosomal micro-RNA-200b-3p from hypoxia cancer-associated fibroblasts reduces sensitivity to 5-flourouracil in colorectal cancer through targeting high-mobility group box 3.
Yuan H, Chen B, Chai R, Gong W, Wan Z, Zheng B, Hu X, Guo Y, Gao S, Dai Q, Yu P, Tu S
Frontiers in oncology 2022;12:920131
Frontiers in oncology 2022;12:920131
TFAP2C-Mediated lncRNA PCAT1 Inhibits Ferroptosis in Docetaxel-Resistant Prostate Cancer Through c-Myc/miR-25-3p/SLC7A11 Signaling.
Jiang X, Guo S, Xu M, Ma B, Liu R, Xu Y, Zhang Y
Frontiers in oncology 2022;12:862015
Frontiers in oncology 2022;12:862015
Clinical Impact of the Histopathological Index and Neuroimaging Features Status in Primary Central Nervous System Diffuse Large B-Cell Lymphoma: A Single-Center Retrospective Analysis of 51 Cases.
Qi Z, Duan L, Yuan G, Liu J, Li J, Li G, Yu Y, Xu Y, Ma S, Pan Y, Zhang Y
Frontiers in oncology 2022;12:769895
Frontiers in oncology 2022;12:769895
PGM3 regulates beta-catenin activity to promote colorectal cancer cell progression.
Zhang N, Liu S, Xu J, Ning T, Xie S, Min L, Zhu S, Zhang S, Zhu S
Experimental biology and medicine (Maywood, N.J.) 2022 Sep;247(17):1518-1528
Experimental biology and medicine (Maywood, N.J.) 2022 Sep;247(17):1518-1528
MED16 Promotes Tumour Progression and Tamoxifen Sensitivity by Modulating Autophagy through the mTOR Signalling Pathway in ER-Positive Breast Cancer.
Li H, Li K, Shu D, Shen M, Tan Z, Zhang W, Pu D, Tan W, Tang Z, Jin A, Liu S
Life (Basel, Switzerland) 2022 Sep 20;12(10)
Life (Basel, Switzerland) 2022 Sep 20;12(10)
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
Yao H, Ren D, Wang Y, Wu L, Wu Y, Wang W, Li Q, Liu L
Cell death & disease 2022 Sep 2;13(9):761
Cell death & disease 2022 Sep 2;13(9):761
Comprehensive comparison between azacytidine and decitabine treatment in an acute myeloid leukemia cell line.
Aumer T, Gremmelmaier CB, Runtsch LS, Pforr JC, Yeşiltaç GN, Kaiser S, Traube FR
Clinical epigenetics 2022 Sep 11;14(1):113
Clinical epigenetics 2022 Sep 11;14(1):113
A novel Gboxin analog induces OXPHOS inhibition and mitochondrial dysfunction-mediated apoptosis in diffuse large B-cell lymphoma.
Yao S, Yin J, Liu W, Li Y, Huang J, Qi C, Hu Z, Tong Q, Gu L, Zhang Y
Bioorganic chemistry 2022 Oct;127:106019
Bioorganic chemistry 2022 Oct;127:106019
KLHL38 facilitates staurosporine-induced apoptosis in HL-1 cells via myocardin degradation.
Luo Y, Tian L, Liang C, Xu Y
IUBMB life 2022 May;74(5):446-462
IUBMB life 2022 May;74(5):446-462
Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis.
Wang R, Peng C, Song J, Hua Y, Wu Q, Deng L, Cao Y, Zhang J, Zhang L, Wu L, Hou L
International journal of oncology 2022 Mar;60(3)
International journal of oncology 2022 Mar;60(3)
Co-delivery of photosensitizer and diclofenac through sequentially responsive bilirubin nanocarriers for combating hypoxic tumors.
Zhou Y, Tong F, Gu W, He S, Yang X, Li J, Gao YD, Gao H
Acta pharmaceutica Sinica. B 2022 Mar;12(3):1416-1431
Acta pharmaceutica Sinica. B 2022 Mar;12(3):1416-1431
TGF-β1-induced RAP2 regulates invasion in pancreatic cancer.
Jin K, Liu C, Cheng H, Fei Q, Huang Q, Xiao Z, Yu X, Wu W
Acta biochimica et biophysica Sinica 2022 Mar 25;54(3):361-369
Acta biochimica et biophysica Sinica 2022 Mar 25;54(3):361-369
Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.
Ji R, Shi Q, Cao Y, Zhang J, Zhao C, Zhao H, Sayyed Y, Fu L, Li LY
The Journal of biological chemistry 2022 Jun;298(6):102033
The Journal of biological chemistry 2022 Jun;298(6):102033
INPP5F translocates into cytoplasm and interacts with ASPH to promote tumor growth in hepatocellular carcinoma.
Zhou Q, Lin J, Yan Y, Meng S, Liao H, Chen R, He G, Zhu Y, He C, Mao K, Wang J, Zhang J, Zhou Z, Xiao Z
Journal of experimental & clinical cancer research : CR 2022 Jan 7;41(1):13
Journal of experimental & clinical cancer research : CR 2022 Jan 7;41(1):13
SLCO4A1-AS1 promotes colorectal tumourigenesis by regulating Cdk2/c-Myc signalling.
Zhang J, Cui K, Huang L, Yang F, Sun S, Bian Z, Wang X, Li C, Yin Y, Huang S, Zhou L, Fei B, Huang Z
Journal of biomedical science 2022 Jan 17;29(1):4
Journal of biomedical science 2022 Jan 17;29(1):4
Kinesin family member 23 exerts a protumor function in breast cancer via stimulation of the Wnt/β-catenin pathway.
He X, Wang J, Zhou R, Yu S, Jiang J, Zhou Q
Toxicology and applied pharmacology 2022 Jan 15;435:115834
Toxicology and applied pharmacology 2022 Jan 15;435:115834
Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.
Tang W, Xue J, Luo L, Wang Y, Cai X, Liu Y, Huang D, Wang X, He T, Lu D, Yang F
Molecular medicine reports 2022 Feb;25(2)
Molecular medicine reports 2022 Feb;25(2)
MxB inhibits long interspersed element type 1 retrotransposition.
Huang Y, Xu F, Mei S, Liu X, Zhao F, Wei L, Fan Z, Hu Y, Wang L, Ai B, Cen S, Liang C, Guo F
PLoS genetics 2022 Feb;18(2):e1010034
PLoS genetics 2022 Feb;18(2):e1010034
The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis.
Zhu Y, Jin L, Shi R, Li J, Wang Y, Zhang L, Liang CZ, Narayana VK, De Souza DP, Thorne RF, Zhang LR, Zhang XD, Wu M
Molecular cell 2022 Feb 3;82(3):542-554.e6
Molecular cell 2022 Feb 3;82(3):542-554.e6
ALG8 Fuels Stemness Through Glycosylation of the WNT/Beta-Catenin Signaling Pathway in Colon Cancer.
Wu X, Wang B, Su Y, He D, Mo H, Zheng M, Meng Z, Ren L, Zhang X, Ren D, Li C
DNA and cell biology 2022 Dec;41(12):1075-1083
DNA and cell biology 2022 Dec;41(12):1075-1083
The ubiquitination of CKIP-1 mediated by Src aggravates diabetic renal fibrosis (original article).
Yang Y, Xiao H, Lin Z, Chen R, Li S, Li C, Sun X, Hei Z, Gong W, Huang H
Biochemical pharmacology 2022 Dec;206:115339
Biochemical pharmacology 2022 Dec;206:115339
Inhibition of cell proliferation by Tas of foamy viruses through cell cycle arrest or apoptosis underlines the different mechanisms of virus-host interactions.
Jie W, Rui-Fen Z, Zhong-Xiang H, Yan W, Wei-Na L, Yong-Ping M, Jing S, Jing-Yi C, Wan-Hong L, Xiao-Hua H, Zhi L, Yan S
Virulence 2022 Dec;13(1):342-354
Virulence 2022 Dec;13(1):342-354
Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1-Wnt/β-catenin-TFE3 feedback loop signalling.
Luo Y, Huang S, Wei J, Zhou H, Wang W, Yang J, Deng Q, Wang H, Fu Z
Clinical and translational medicine 2022 Apr;12(4):e752
Clinical and translational medicine 2022 Apr;12(4):e752
Mitochondrial fragmentation is crucial for c-Myc-driven hepatoblastoma-like liver tumors.
Wang D, Tian J, Yan Z, Yuan Q, Wu D, Liu X, Yang S, Guo S, Wang J, Yang Y, Xing J, An J, Huang Q
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Apr 6;30(4):1645-1660
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Apr 6;30(4):1645-1660
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Gao M, Yang J, Gong H, Lin Y, Liu J
Frontiers in pharmacology 2021;12:760055
Frontiers in pharmacology 2021;12:760055
Epilepsy-Associated UBE3A Deficiency Downregulates Retinoic Acid Signalling Pathway.
Fang M, Li Y, Ren J, Hu R, Gao X, Chen L
Frontiers in genetics 2021;12:681295
Frontiers in genetics 2021;12:681295
Swine Acute Diarrhea Syndrome Coronavirus Nucleocapsid Protein Antagonizes Interferon-β Production via Blocking the Interaction Between TRAF3 and TBK1.
Zhou Z, Sun Y, Xu J, Tang X, Zhou L, Li Q, Lan T, Ma J
Frontiers in immunology 2021;12:573078
Frontiers in immunology 2021;12:573078
Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1.
Wang M, Liu H, Zhang X, Zhao W, Li D, Xu C, Wu Z, Xie F, Li X
Journal of cellular physiology 2021 Sep;236(9):6559-6570
Journal of cellular physiology 2021 Sep;236(9):6559-6570
Distinguishable Targeting of Non-Small Cell Lung Cancer Using Hyaluronan Functionalized Platinum Nanoclusters and Their Inhibition Behaviors of Proliferation, Invasion, Migration.
Liu T, Huang X, Zhao L, Xiao Z, Li Z, Xin Y, Yang S, Guo D, Zhao W, Mi Y, Li H
ChemistryOpen 2021 Sep;10(9):882-888
ChemistryOpen 2021 Sep;10(9):882-888
Compound heterozygous KCNV2 variants contribute to cone dystrophy with supernormal rod responses in a Chinese family.
Liu M, Zhu Y, Huang L, Jiang W, Wu N, Song Y, Lu Y, Ma Y
Molecular genetics & genomic medicine 2021 Oct;9(10):e1795
Molecular genetics & genomic medicine 2021 Oct;9(10):e1795
E3 ligase TRIM25 ubiquitinates RIP3 to inhibit TNF induced cell necrosis.
Mei P, Xie F, Pan J, Wang S, Gao W, Ge R, Gao B, Gao S, Chen X, Wang Y, Wu J, Ding C, Li J
Cell death and differentiation 2021 Oct;28(10):2888-2899
Cell death and differentiation 2021 Oct;28(10):2888-2899
DOC-2/DAB2 interactive protein destabilizes c-Myc to impair the growth and self-renewal of colon tumor-repopulating cells.
Li H, Zhou Y, Wang M, Wang H, Zhang Y, Peng R, Zhang R, Zhang M, Zhang M, Qiu P, Liu L, Zhao Q, Liu J
Cancer science 2021 Nov;112(11):4593-4603
Cancer science 2021 Nov;112(11):4593-4603
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
Wang D, Ye Z, Wei W, Yu J, Huang L, Zhang H, Yue J
eLife 2021 Nov 19;10
eLife 2021 Nov 19;10
The NF-κB signalling pathway and TM7SF3 contribute to liver fibrosis caused by secreted phospholipase A2 of Clonorchis sinensis.
Wu YJ, He Q, Shang M, Yin YX, Li Y, Du X, Li XR
Parasites & vectors 2021 Mar 10;14(1):152
Parasites & vectors 2021 Mar 10;14(1):152
DEK is highly expressed in breast cancer and is associated with malignant phenotype and progression.
Yang MQ, Bai LL, Wang Z, Lei L, Zheng YW, Li ZH, Huang WJ, Liu CC, Xu HT
Oncology letters 2021 Jun;21(6):440
Oncology letters 2021 Jun;21(6):440
CircMTO1 suppresses hepatocellular carcinoma progression via the miR-541-5p/ZIC1 axis by regulating Wnt/β-catenin signaling pathway and epithelial-to-mesenchymal transition.
Li D, Zhang J, Yang J, Wang J, Zhang R, Li J, Zhang R
Cell death & disease 2021 Dec 20;13(1):12
Cell death & disease 2021 Dec 20;13(1):12
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
Guan Y, Li Y, Yang QB, Yu J, Qiao H
Annals of translational medicine 2021 Apr;9(8):664
Annals of translational medicine 2021 Apr;9(8):664
LIMK1 nuclear translocation promotes hepatocellular carcinoma progression by increasing p-ERK nuclear shuttling and by activating c-Myc signalling upon EGF stimulation.
Pan Z, Liu C, Zhi Y, Xie Z, Wu L, Jiang M, Zhang Y, Zhou R, Zhao L
Oncogene 2021 Apr;40(14):2581-2595
Oncogene 2021 Apr;40(14):2581-2595
p53-targeted lncRNA ST7-AS1 acts as a tumour suppressor by interacting with PTBP1 to suppress the Wnt/β-catenin signalling pathway in glioma.
Sheng J, He X, Yu W, Chen Y, Long Y, Wang K, Zhu S, Liu Q
Cancer letters 2021 Apr 10;503:54-68
Cancer letters 2021 Apr 10;503:54-68
PRV-encoded UL13 protein kinase acts as an antagonist of innate immunity by targeting IRF3-signaling pathways.
Lv L, Cao M, Bai J, Jin L, Wang X, Gao Y, Liu X, Jiang P
Veterinary microbiology 2020 Nov;250:108860
Veterinary microbiology 2020 Nov;250:108860
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
Gong C, Hu X, Xu Y, Yang J, Zong L, Wang C, Zhu J, Li Z, Lu D
Anti-cancer drugs 2020 Feb;31(2):141-149
Anti-cancer drugs 2020 Feb;31(2):141-149
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