Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 20437-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20437-1-AP, RRID:AB_10666853
- Product name
- RNF6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RNF6 antibody (Cat. #20437-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Tree Shrew Genome-Wide CRISPR Screen Identifies RNF6 as a Proviral Host Factor for Zika Virus Replication in Brain Microvascular Endothelial Cells.
Albanol B inhibits glioblastoma progression by inducing senescence and apoptosis via the RNF6/p27 signaling axis.
RNF6 promotes cell proliferation of glioblastoma by targeting ubiquitin-mediated degradation of p27.
CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1-Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis.
Non-adherent culture method affects the proliferation and apoptosis of mesenchymal stem cells through inhibiting LINC00707 to promote RNF6-mediated QKI ubiquitination.
TRIM26 promotes non-small cell lung cancer survival by inducing PBX1 degradation.
Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia.
Ring finger protein 6 enhances chemo-resistance by transcriptionally activating proliferating cell nuclear antigen expression and attenuating DNA damage in lung adenocarcinoma.
RING-finger protein 6 promotes colorectal tumorigenesis by transcriptionally activating SF3B2.
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
miR-203a suppresses cell proliferation by targeting RING-finger protein 6 in colorectal cancer.
Qi M, Liu X, Wang W, Lu M, Zeng Q, Li N, Han Y, Fan S, Lu C, Dai J
Viruses 2026 Mar 5;18(3)
Viruses 2026 Mar 5;18(3)
Albanol B inhibits glioblastoma progression by inducing senescence and apoptosis via the RNF6/p27 signaling axis.
Hou J, Du Y, Shao Y, Chang H, Shi J, Cao X, Wang Y, Xu J, Liang P, Cui H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157056
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157056
RNF6 promotes cell proliferation of glioblastoma by targeting ubiquitin-mediated degradation of p27.
Hou J, Du Y, Cui H
Biochemical and biophysical research communications 2025 Mar 8;752:151460
Biochemical and biophysical research communications 2025 Mar 8;752:151460
CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1-Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis.
Han J, Hong R, Cao C, Feng W, Zhuang W, Wang G, Tang J, Yang Y, Zhang C, Zhou A, Qu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414550
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414550
Non-adherent culture method affects the proliferation and apoptosis of mesenchymal stem cells through inhibiting LINC00707 to promote RNF6-mediated QKI ubiquitination.
Deng B, Deng W, Zheng H, Wei Y, Zhang J, Zeng N, He Y, Guo R
Experimental cell research 2024 Jan 1;434(1):113877
Experimental cell research 2024 Jan 1;434(1):113877
TRIM26 promotes non-small cell lung cancer survival by inducing PBX1 degradation.
Sun Y, Lin P, Zhou X, Ren Y, He Y, Liang J, Zhu Z, Xu X, Mao X
International journal of biological sciences 2023;19(9):2803-2816
International journal of biological sciences 2023;19(9):2803-2816
Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia.
Zhuang H, Ren Y, Mao C, Zhong Y, Zhang Z, Cao B, Zhang Y, Huang J, Xu G, Huang Z, Xu Y, Mao X
The Journal of biological chemistry 2022 Sep;298(9):102314
The Journal of biological chemistry 2022 Sep;298(9):102314
Ring finger protein 6 enhances chemo-resistance by transcriptionally activating proliferating cell nuclear antigen expression and attenuating DNA damage in lung adenocarcinoma.
Sun Y, Sun H, Qi Y, Pan M, An N, Leng X, Liu Y, Chen Z
Cancer letters 2022 May 28;534:215609
Cancer letters 2022 May 28;534:215609
RING-finger protein 6 promotes colorectal tumorigenesis by transcriptionally activating SF3B2.
Xu H, Wong CC, Li W, Zhou Y, Li Y, Wang L, Liu L, Yu J
Oncogene 2021 Nov;40(47):6513-6526
Oncogene 2021 Nov;40(47):6513-6526
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Ren Y, Xu X, Mao CY, Han KK, Xu YJ, Cao BY, Zhang ZB, Sethi G, Tang XW, Mao XL
Acta pharmacologica Sinica 2020 Mar;41(3):394-403
Acta pharmacologica Sinica 2020 Mar;41(3):394-403
miR-203a suppresses cell proliferation by targeting RING-finger protein 6 in colorectal cancer.
Miao J, Hou N, Yang W, Jiang Q, Xue W, Wang X, Zhang H, Xiong X, Wang L, Zhao L, Huang C
Anti-cancer drugs 2020 Jul;31(6):583-591
Anti-cancer drugs 2020 Jul;31(6):583-591
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 20437-1-AP(RNF6 antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using RNF6 antibody 20437-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
