CABT-BL4375

antibody from Creative Diagnostics

Targeting: CLDN12

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-BL4375

Provider

Creative Diagnostics

Product name

Anti-CLDN12 (aa 26-54) polyclonal antibody

Antibody type

Polyclonal

Description

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq, Sep 2011]

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 _g

Storage

Store at 4°C (up to 6 months). For long term storage store at -20°C