BS60972
antibody from Bioworld Technology, Inc
Targeting: IL36RN
FIL1, FIL1(DELTA), FIL1D, IL-1F5, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, MGC29840
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS60972 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- IL36RN polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human IL36RN.
- Description
- IL-1 (Interleukin-1) is a cytokine responsible for initiating a variety of activities through the activation of transcription factors, NF°ÙB and AP-1, thereby promoting host response to injury or infection. The IL-1 superfamily is comprised of several ligands and receptors. IL-1F5, also known as IL-1Ñ´, IL-1 like protein 1 (IL-1L1), IL-1HY1, IL-1ra (receptor antagonist) homolog 1 or IL-1 related protein 3 (IL-1rp3), is a secreted ligand belonging to this superfamily. IL-1F5 is expressed in monocytes and macrophages and is activated by endotoxins. It shares 47% sequence identity with IL-1ra and similarly lacks the loop between the fourth and fifth ¡Â-strands. IL-1F5 acts as an antagonist, inhibiting the IL-1F9 activation of NF°ÙB. Similar to other family members, IL-1F5 can be regulated by bacterial lipopolysaccharide (LPS).
- Reactivity
- Human, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of IL36RN pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:H9C2 whole cell lysate