RA0387

antibody from Oursmab

Targeting: IL36RN FIL1, FIL1(DELTA), FIL1D, IL-1F5, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, MGC29840

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0387

Provider

Oursmab

Product name

Spesolimab (Biosimilar Reference Antibody) (IL36RN)

Antibody type

Monoclonal

Description

Spesolimab is a humanized monoclonal antibody targeting the interleukin-36 receptor (IL-36R). It binds to IL-36R, blocking the signaling of pro-inflammatory cytokines IL-36¦Á, ¦Â, and ¦Ã. It is approved for the treatment of generalized pustular psoriasis (GPP) flares in adults, rapidly reducing pustules and systemic inflammation.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Spesolimab (Biosimilar Reference Antibody) (IL36RN)-RA0387-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Spesolimab (Biosimilar Reference Antibody) (IL36RN)-RA0387 in a linear range of 15.63¨C125 ng/mL.