66042-1-Ig

antibody from Proteintech Group

Targeting: FN1 CIG, FINC, GFND2, LETS, MSF

Provider product page for 66042-1-Ig

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [106]
Comments [0]
Validations
Western blot [1]

Submit

Product number: 66042-1-Ig - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#66042-1-Ig, RRID:AB_11182385
Product name: Fibronectin antibody
Antibody type: Monoclonal
Description: KD/KO validated Fibronectin antibody (Cat. #66042-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 1G10F9
Vial size: 20ul, 150ul

FN1 protein structure - 66042-1-Ig shown in red.

Submitted references Development and Validation of the Diagnostic Model of 7 Gene in Endometriosis.

Zhu R, Liu Y, Zhou J, Lv Z, Shi K, Xiong J
Current medicinal chemistry 2024;31(41):6871-6888

Integrated analysis reveals crosstalk between pyroptosis and immune regulation in renal fibrosis.

Bai F, Han L, Yang J, Liu Y, Li X, Wang Y, Jiang R, Zeng Z, Gao Y, Zhang H
Frontiers in immunology 2024;15:1247382

Single-cell analysis reveals one cancer-associated fibroblasts subtype linked to metastasis in breast cancer: MXRA5 as a potential novel marker for prognosis.

Deng H, Wen C, Jiang S, Yu Y, Zhao J, Zhang B
American journal of cancer research 2024;14(2):526-544

Adipose-derived stem cells derived decellularized extracellular matrix enabled skin regeneration and remodeling.

Zhang J, Xiang Y, Yang Q, Chen J, Liu L, Jin J, Zhu S
Frontiers in bioengineering and biotechnology 2024;12:1347995

Counteracting TGM2 by a Fibroin peptide ameliorated Adriamycin-induced nephropathy via regulation of lipid metabolism through PANX1-PPAR α/PANK1 pathway.

Li SS, Liu QJ, Bao JX, Lu MT, Deng BQ, Li WW, Cao CC
Translational research : the journal of laboratory and clinical medicine 2024 Sep;271:26-39

Inhibition of CK2 Diminishes Fibrotic Scar Formation and Improves Outcomes After Ischemic Stroke via Reducing BRD4 Phosphorylation.

Li X, Yang Q, Jiang P, Wen J, Chen Y, Huang J, Tian M, Ren J, Yang Q
Neurochemical research 2024 May;49(5):1254-1267

Targeting ROCK2 improves macromolecular permeability in a 3D fibrotic pancreatic cancer microenvironment model.

Tanaka HY, Nakazawa T, Miyazaki T, Cabral H, Masamune A, Kano MR
Journal of controlled release : official journal of the Controlled Release Society 2024 May;369:283-295

Targeted delivery of the probiotic Saccharomyces boulardii to the extracellular matrix enhances gut residence time and recovery in murine colitis.

Heavey MK, Hazelton A, Wang Y, Garner M, Anselmo AC, Arthur JC, Nguyen J
Nature communications 2024 May 6;15(1):3784

FOXF1 reverses lung fibroblasts transdifferentiation via inhibiting TGF-β/SMAD2/3 pathway in silica-induced pulmonary fibrosis.

Hu B, Zhang X, Fan H, Jin X, Qi Y, Liu R, Li X, Duan M, Zhang C, Li S, Yao W, Hao C
International immunopharmacology 2024 May 30;133:112067

Diffusion barriers imposed by tissue topology shape morphogen gradients.

Schlissel G, Meziane M, Narducci D, Hansen AS, Li P
bioRxiv : the preprint server for biology 2024 May 2;

Human Placenta Decellularized Extracellular Matrix Hydrogel Promotes the Generation of Human Spinal Cord Organoids with Dorsoventral Organization from Human Induced Pluripotent Stem Cells.

Wang Z, Liu R, Liu Y, Zhao Y, Wang Y, Lu B, Li H, Ju C, Wu W, Gao X, Xu H, Cheng S, Cao Y, Jia S, Hu C, Zhu L, Hao D
ACS biomaterials science & engineering 2024 May 13;10(5):3218-3231

Decellularized Brain Extracellular Matrix Hydrogel Aids the Formation of Human Spinal-Cord Organoids Recapitulating the Complex Three-Dimensional Organization.

Wu W, Liu Y, Liu R, Wang Y, Zhao Y, Li H, Lu B, Ju C, Gao X, Xu H, Cao Y, Cheng S, Wang Z, Jia S, Hu C, Zhu L, Hao D
ACS biomaterials science & engineering 2024 May 13;10(5):3203-3217

Multi-omics integration highlights the role of ubiquitination in endometriosis fibrosis.

Yang M, Jiang H, Ding X, Zhang L, Zhang H, Chen J, Li L, He X, Huang Z, Chen Q
Journal of translational medicine 2024 May 12;22(1):445

Exosomal miR-17-5p derived from epithelial cells is involved in aberrant epithelium-fibroblast crosstalk and induces the development of oral submucosal fibrosis.

Xie C, Zhong L, Feng H, Wang R, Shi Y, Lv Y, Hu Y, Li J, Xiao D, Liu S, Chen Q, Tao Y
International journal of oral science 2024 Jun 20;16(1):48

Inhibition of miR-25 ameliorates cardiac and skeletal muscle dysfunction in aged mdx/utrn haploinsufficient (+/-) mice.

Kepreotis SV, Oh JG, Park M, Yoo J, Lee C, Mercola M, Hajjar RJ, Jeong D
Molecular therapy. Nucleic acids 2024 Jun 11;35(2):102174

Metabolic reprogramming driven by EZH2 inhibition depends on cell-matrix interactions.

W-M Fan T, Islam JMM, Higashi RM, Lin P, Brainson CF, Lane AN
The Journal of biological chemistry 2024 Jan;300(1):105485

Overexpression of Corin Ameliorates Kidney Fibrosis through Inhibition of Wnt/β-Catenin Signaling in Mice.

Su X, Li S, Zhang Y, Tie X, Feng R, Guo X, Qiao X, Wang L
The American journal of pathology 2024 Jan;194(1):101-120

Rare genetic variation in Fibronectin 1 ( FN1 ) protects against APOEe4 in Alzheimer's disease.

Bhattarai P, Gunasekaran TI, Reyes-Dumeyer D, Jülich D, Tayran H, Yilmaz E, Flaherty D, Lantigua R, Medrano M, Rivera D, Recio P, Ertekin-Taner N, Teich AF, Dickson DW, Holley S, Mayeux R, Kizil C, Vardarajan BN
bioRxiv : the preprint server for biology 2024 Jan 2;

The TGFβ1/SMADs/Snail1 signaling axis mediates pericyte-derived fibrous scar formation after spinal cord injury.

Huang Y, Liu R, Meng T, Zhang B, Ma J, Liu X
International immunopharmacology 2024 Feb 15;128:111482

TGF-β2-induced alterations of m6A methylation in hTERT RPE-1 cells.

Li X, Zhao X, Yin R, Yuan M, Zhang Y, Li X
Experimental eye research 2024 Apr;241:109839

Microbial imidazole propionate affects glomerular filtration rate in patients with diabetic nephropathy through association with HSP90α.

Lv D, Zheng W, Zhang Z, Lin Z, Wu K, Liu H, Liao X, Sun Y
Biochimica et biophysica acta. Molecular cell research 2024 Apr;1871(4):119703

PI3Kδ Mediates Fibrosis by Patient-Derived Vitreous.

Liu D, Yan B, Yin Y, Chen F, Guo C, Li Q, Liu J, Pu L, Wu W, Luo J
Laboratory investigation; a journal of technical methods and pathology 2024 Apr;104(4):102026

PDGFRα(+)ITGA11(+) fibroblasts foster early-stage cancer lymphovascular invasion and lymphatic metastasis via ITGA11-SELE interplay.

Zheng H, An M, Luo Y, Diao X, Zhong W, Pang M, Lin Y, Chen J, Li Y, Kong Y, Zhao Y, Yin Y, Ai L, Huang J, Chen C, Lin T
Cancer cell 2024 Apr 8;42(4):682-700.e12

Leech extract alleviates idiopathic pulmonary fibrosis by TGF-β1/Smad3 signaling pathway.

Zhang Y, Lu YB, Zhu WJ, Gong XX, Qian R, Lu YJ, Li Y, Yao WF, Bao BH, Zhang Y, Zhang L, Cheng FF
Journal of ethnopharmacology 2024 Apr 24;324:117737

The NF-κB/NUAK2 signaling axis regulates pancreatic cancer progression by targeting SMAD2/3.

Wang R, Su D, Liu Y, Huang H, Qiu J, Cao Z, Yang G, Chen H, Luo W, Tao J, Weng G, Zhang T
iScience 2024 Apr 19;27(4):109406

Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease.

Bhattarai P, Gunasekaran TI, Belloy ME, Reyes-Dumeyer D, Jülich D, Tayran H, Yilmaz E, Flaherty D, Turgutalp B, Sukumar G, Alba C, McGrath EM, Hupalo DN, Bacikova D, Le Guen Y, Lantigua R, Medrano M, Rivera D, Recio P, Nuriel T, Ertekin-Taner N, Teich AF, Dickson DW, Holley S, Greicius M, Dalgard CL, Zody M, Mayeux R, Kizil C, Vardarajan BN
Acta neuropathologica 2024 Apr 10;147(1):70

Pseudobudding: ruptured glands do not represent true tumor buds.

Haddad TS, van den Dobbelsteen L, Öztürk SK, Geene R, Nijman IJ, Verrijp K, Jamieson NB, Wood C, van Vliet S, Reuvers L, Achouiti S, Rutgers N, Brouwer N, Simmer F, Zlobec I, Lugli A, Nagtegaal ID
The Journal of pathology 2023 Sep;261(1):19-27

A multifunctional polydopamine/genipin/alendronate nanoparticle licences fibrin hydrogels osteoinductive and immunomodulatory potencies for repairing bone defects.

Shi W, Gao Y, Wu Y, Sun J, Xu B, Lu X, Wang Q
International journal of biological macromolecules 2023 Sep 30;249:126072

Inhibition of miR-195-3p protects against cardiac dysfunction and fibrosis after myocardial infarction.

Carvalho A, Ji Z, Zhang R, Zuo W, Qu Y, Chen X, Tao Z, Ji J, Yao Y, Ma G
International journal of cardiology 2023 Sep 15;387:131128

FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.

Chen C, Ye L, Yi J, Liu T, Li Z
Breast cancer research and treatment 2023 Oct;201(3):515-533

M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats.

Huang JG, Ren JX, Chen Y, Tian MF, Zhou L, Wen J, Song XS, Wu YL, Yang QH, Jiang PR, Wang JN, Yang Q
Neural regeneration research 2023 Oct;18(10):2208-2218

Nintedanib inhibits normal human vitreous-induced epithelial-mesenchymal transition in human retinal pigment epithelial cells.

Yin Y, Liu S, Liu H, Wu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115403

Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axis.

Xia W, Chen X, Zhu Z, Chen H, Li B, Wang K, Huang L, Liu Z, Chen Z
Scientific reports 2023 Oct 23;13(1):18076

Alleviative effect of melatonin against the nephrotoxicity induced by cadmium exposure through regulating renal oxidative stress, inflammatory reaction, and fibrosis in a mouse model.

Yang Z, He Y, Ma Q, Wang H, Zhang Q
Ecotoxicology and environmental safety 2023 Oct 15;265:115536

Schisandrin B Alleviates Renal Tubular Cell Epithelial-Mesenchymal Transition and Mitochondrial Dysfunction by Kielin/Chordin-like Protein Upregulation via Akt Pathway Inactivation and Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase Pathway Activation in Diabetic Kidney Disease.

Liu W, Li F, Guo D, Du C, Zhao S, Li J, Yan Z, Hao J
Molecules (Basel, Switzerland) 2023 Nov 29;28(23)

Nintedanib prevents TGF-β2-induced epithelial-mesenchymal transition in retinal pigment epithelial cells.

Yin Y, Liu S, Pu L, Luo J, Liu H, Wu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114543

Long-term exercise preserves pancreatic islet structure and β-cell mass through attenuation of islet inflammation and fibrosis.

Carvalho VHC, Wang Q, Xu X, Liu L, Jiang W, Wang X, Wang J, Li W, Chen J, Li T, Chen Y, Zhu W, Sun Z, Qiu S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22822

Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling.

Wu H, Tang LX, Wang XM, Li LP, Chen XK, He YJ, Yang DZ, Shi Y, Shou JL, Zhang ZS, Wang L, Lu BJ, An SM, Zeng CY, Wang WE
Acta pharmacologica Sinica 2023 Jun;44(6):1149-1160

Regulon analysis identifies protective FXR and CREB5 in proximal tubules in early diabetic kidney disease.

Shi W, Le W, Tang Q, Shi S, Shi J
BMC nephrology 2023 Jun 19;24(1):180

Intestinal Cckbr-specific knockout mouse as a novel model of salt-sensitive hypertension via sodium over-absorption.

Zhang QY, Guo Y, Jiang XL, Liu X, Zhao SG, Zhou XL, Yang ZW
Journal of geriatric cardiology : JGC 2023 Jul 28;20(7):538-547

Integrin β6 mediates epithelial-mesenchymal transition in diabetic kidney disease.

Li X, Miao Y, Li T, Liu X, Xu L, Guo J, Yu X, Sun B, Zhu Y, Ai D, Chen L
Molecular and cellular endocrinology 2023 Jul 15;572:111955

Yishen-Qingli-Huoxue formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling.

Chen C, Sun S, Zhao J, Wu Q, He W, Sun W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154546

A2aR inhibits fibrosis and the EMT process in silicosis by regulating Wnt/β-catenin pathway.

Tian Y, Xia J, Yang G, Li C, Qi Y, Dai K, Wu C, Guo Y, Yao W, Hao C
Ecotoxicology and environmental safety 2023 Jan 1;249:114410

MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells.

Xia J, Tian Y, Shao Z, Li C, Ding M, Qi Y, Xu X, Dai K, Wu C, Yao W, Hao C
Ecotoxicology and environmental safety 2023 Jan 1;249:114392

Effects of substrate topography on the regulation of human fibroblasts and capsule formation via modulating macrophage polarization.

Chen C, Chen Y, Lan YJ, Tian MN, Zhang YM, Lei ZY, Fan DL
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113086

Exosomes derived from human umbilical cord mesenchymal stem cells loaded with RVG-Lamp2b and Netrin-1 promotes Schwann cell invasion and migration.

He J, Du Z, Zhang H, Wang B, Xia J
Tissue & cell 2023 Dec;85:102219

Genome-wide transcriptional responses of osteoblasts to different titanium surface topographies.

Komatsu K, Matsuura T, Suzumura T, Ogawa T
Materials today. Bio 2023 Dec;23:100852

Clinical and functional characterization of COL2A1 p.Gly444Ser variant: From a fetal phenotype to a previously undisclosed postnatal phenotype.

Marchionni E, D'Apice MR, Lupo V, Lattanzi G, Mattioli E, Lisignoli G, Gabusi E, Pepe G, Helmer Citterich M, Campione E, Nardone AM, Spitalieri P, Pucci N, Cocciadiferro D, Picchi E, Garaci F, Novelli A, Novelli G
Bone reports 2023 Dec;19:101728

Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction.

Tan E, Gao Z, Wang Q, Han B, Shi H, Wang L, Zhu G, Hou Y
Basic & clinical pharmacology & toxicology 2023 Dec;133(6):757-769

Reprogramming of VEGF-mediated extracellular matrix changes through autocrine signaling.

Goggins E, Mironchik Y, Kakkad S, Jacob D, Wildes F, Bhujwalla ZM, Krishnamachary B
Cancer biology & therapy 2023 Dec 31;24(1):2184145

Exploring the Role of Lycium barbarum Polysaccharide in Corneal Injury Repair and Investigating the Relevant Mechanisms through In Vivo and In Vitro Experiments.

Liu Q, Nan Y, Yang Y, Li X, Jiang W, Jiao T, Li J, Jia X, Ye M, Niu Y, Yuan L
Molecules (Basel, Switzerland) 2023 Dec 20;29(1)

Single cell transcriptomic analyses implicate an immunosuppressive tumor microenvironment in pancreatic cancer liver metastasis.

Zhang S, Fang W, Zhou S, Zhu D, Chen R, Gao X, Li Z, Fu Y, Zhang Y, Yang F, Zhao J, Wu H, Wang P, Shen Y, Shen S, Xu G, Wang L, Yan C, Zou X, Chen D, Lv Y
Nature communications 2023 Aug 23;14(1):5123

A novel mechanism regulating pyroptosis-induced fibrosis in endometriosis via lnc-MALAT1/miR-141-3p/NLRP3 pathway†.

Xu Y, Liu H, Xiong W, Peng Y, Li X, Long X, Jin J, Liang J, Weng R, Liu J, Zhang L, Liu Y
Biology of reproduction 2023 Aug 10;109(2):156-171

LncRNA CFAR promotes cardiac fibrosis via the miR-449a-5p/LOXL3/mTOR axis.

Zhang M, Zhang B, Wang X, Song J, Tong M, Dong Z, Xu J, Liu M, Jiang Y, Wang N, Wang Y, Du Z, Liu Y, Zhang R, Xu C
Science China. Life sciences 2023 Apr;66(4):783-799

Nitration of cAMP-Response Element Binding Protein Participates in Myocardial Infarction-Induced Myocardial Fibrosis via Accelerating Transcription of Col1a2 and Cxcl12.

Xue K, Chen S, Chai J, Yan W, Zhu X, Ji D, Wu Y, Liu H, Wang W
Antioxidants & redox signaling 2023 Apr;38(10-12):709-730

Hepatoblastoma: Derived Exosomal LncRNA NEAT1 Induces BMSCs Differentiation into Tumor-Supporting Myofibroblasts via Modulating the miR-132/MMP9 Axis.

Hu Y, Zai H, Jiang W, Ou Z, Yao Y, Zhu Q
Journal of oncology 2022;2022:7630698

miR-486-5p Restrains Extracellular Matrix Production and Oxidative Damage in Human Trabecular Meshwork Cells by Targeting TGF-β/SMAD2 Pathway.

Xu L, Zhang Y, Long H, Zhou B, Jiang H
Journal of ophthalmology 2022;2022:3584192

HBO1 as an Important Target for the Treatment of CCL4-Induced Liver Fibrosis and Aged-Related Liver Aging and Fibrosis.

Xing B, Lan H, Li H
Oxidative medicine and cellular longevity 2022;2022:1881519

Distinct immune and inflammatory response patterns contribute to the identification of poor prognosis and advanced clinical characters in bladder cancer patients.

Chang Z, Li R, Zhang J, An L, Zhou G, Lei M, Deng J, Yang R, Song Z, Zhong W, Qi D, Duan X, Li S, Sun B, Wu W
Frontiers in immunology 2022;13:1008865

FN1 is a prognostic biomarker and correlated with immune infiltrates in gastric cancers.

Wang H, Zhang J, Li H, Yu H, Chen S, Liu S, Zhang C, He Y
Frontiers in oncology 2022;12:918719

Targeting MALT1 Suppresses the Malignant Progression of Colorectal Cancer via miR-375/miR-365a-3p/NF-κB Axis.

Qian R, Niu X, Wang Y, Guo Z, Deng X, Ding Z, Zhou M, Deng H
Frontiers in cell and developmental biology 2022;10:845048

LncRNA DACH1 protects against pulmonary fibrosis by binding to SRSF1 to suppress CTNNB1 accumulation.

Sun J, Jin T, Niu Z, Guo J, Guo Y, Yang R, Wang Q, Gao H, Zhang Y, Li T, He W, Li Z, Ma W, Su W, Li L, Fan X, Shan H, Liang H
Acta pharmaceutica Sinica. B 2022 Sep;12(9):3602-3617

Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration.

Zhu X, Chen Z, Wang L, Ou Q, Feng Z, Xiao H, Shen Q, Li Y, Jin C, Xu JY, Gao F, Wang J, Zhang J, Zhang J, Xu Z, Xu GT, Lu L, Tian H
Cell death & disease 2022 Sep 12;13(9):785

EP300 promotes renal tubular epithelial cell fibrosis by increasing HIF2α expression in diabetic nephropathy.

Gong Y, Dou Y, Wang L, Wang X, Zhao Z
Cellular signalling 2022 Oct;98:110407

Elimination of senescent cells inhibits epithelial-mesenchymal transition of retinal pigment epithelial cells.

Gao F, Wang L, Wu B, Ou Q, Tian H, Xu J, Jin C, Zhang J, Wang J, Lu L, Xu GT
Experimental eye research 2022 Oct;223:109207

Oncogenic GBX2 promotes the malignant behaviors of bladder cancer cells by binding to the ITGA5 promoter and activating its transcription.

Xiong Y, Song X, Kudusi, Zu X, Chen M, He W, Qi L
Functional & integrative genomics 2022 Oct;22(5):937-950

Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.

Tian H, Chen Z, Zhu X, Ou Q, Wang Z, Wu B, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Lu L, Xu GT
iScience 2022 Oct 21;25(10):105050

The Combined Effects of Circular RNA Methylation Promote Pulmonary Fibrosis.

Wang S, Luo W, Huang J, Chen M, Ding J, Cheng Y, Zhang W, Fang S, Wang J, Chao J
American journal of respiratory cell and molecular biology 2022 May;66(5):510-523

Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.

Shen R, Yang K, Cheng X, Guo C, Xing X, Sun H, Liu D, Liu X, Wang D
Environmental pollution (Barking, Essex : 1987) 2022 May 1;300:118986

Pemafibrate attenuates pulmonary fibrosis by inhibiting myofibroblast differentiation.

Liu Y, Chen S, Yu L, Deng Y, Li D, Yu X, Chen D, Lu Y, Liu S, Chen R
International immunopharmacology 2022 Jul;108:108728

An integrated network pharmacology and cell metabolomics approach to reveal the role of rhein, a novel PPARα agonist, against renal fibrosis by activating the PPARα-CPT1A axis.

Xiao Q, Yu X, Yu X, Liu S, Jiang J, Cheng Y, Lin H, Wang Y, Zhang X, Ye X, Xiang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154147

Heat shock protein Hspa13 regulates endoplasmic reticulum and cytosolic proteostasis through modulation of protein translocation.

Espinoza MF, Nguyen KK, Sycks MM, Lyu Z, Quanrud GM, Montoya MR, Genereux JC
The Journal of biological chemistry 2022 Dec;298(12):102597

The ubiquitination of CKIP-1 mediated by Src aggravates diabetic renal fibrosis (original article).

Yang Y, Xiao H, Lin Z, Chen R, Li S, Li C, Sun X, Hei Z, Gong W, Huang H
Biochemical pharmacology 2022 Dec;206:115339

New triterpenoids from the Cyclocarya paliurus (Batalin) Iljinskaja and their anti-fibrotic activity.

Liu Y, Zhang XX, Xu SS, Fang SY, Zhu LP, Song Z, Shang XL, Fang SZ, Pan K, Cao XL, Yin ZQ
Phytochemistry 2022 Dec;204:113434

Inhibition of BRD4 decreases fibrous scarring after ischemic stroke in rats by inhibiting the phosphorylation of Smad2/3.

Li X, Zhu H, Wen J, Huang J, Chen Y, Tian M, Ren J, Zhou L, Yang Q
Brain research 2022 Dec 15;1797:148126

HIF-1α mediates renal fibrosis by regulating metabolic remodeling of renal tubule epithelial cells.

Liu D, Sun H, Li K, Zhao Z, Liu Z, Zhang G, Ge Y, Zhang J, Wang D, Leng Y
Biochemical and biophysical research communications 2022 Aug 27;618:15-23

Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.

Peng T, He Y, Wang T, Yu J, Ma X, Zhou Z, Sheng Y, Li L, Peng H, Li S, Zou J, Yuan Y, Zhao Y, Shi H, Li F, Liu W, Hu K, Lu X, Zhang G, Wang F
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033

ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma.

Song L, Zhang L, Zhou Y, Shao X, Xu Y, Pei D, Wang Q
Cell death discovery 2022 Apr 21;8(1):219

Aberrant Methylation and Immune Microenvironment Are Associated With Overexpressed Fibronectin 1: A Diagnostic and Prognostic Target in Head and Neck Squamous Cell Carcinoma.

Sheng S, Guo B, Wang Z, Zhang Z, Zhou J, Huo Z
Frontiers in molecular biosciences 2021;8:753563

Weighted correlation network analysis identifies FN1, COL1A1 and SERPINE1 associated with the progression and prognosis of gastric cancer.

Zhao Q, Xie J, Xie J, Zhao R, Song C, Wang H, Rong J, Yan L, Song Y, Wang F, Xie Y
Cancer biomarkers : section A of Disease markers 2021;31(1):59-75

GED-0507 attenuates lung fibrosis by counteracting myofibroblast transdifferentiation in vivo and in vitro.

Speca S, Dubuquoy C, Rousseaux C, Chavatte P, Desreumaux P, Spagnolo P
PloS one 2021;16(9):e0257281

Chinese Herbal Medicine Suyin Detoxification Granule Inhibits Pyroptosis and Epithelial-Mesenchymal Transition by Downregulating MAVS/NLRP3 to Alleviate Renal Injury.

Zhu Y, Huang G, Yang Y, Yong C, Yu X, Wang G, Yi L, Gao K, Tian F, Qian S, Zhou E, Zou Y
Journal of inflammation research 2021;14:6601-6618

B7-H3 inhibits apoptosis of gastric cancer cell by interacting with Fibronectin.

Sun M, Xie J, Zhang D, Chen C, Lin S, Chen Y, Zhang G
Journal of Cancer 2021;12(24):7518-7526

High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease.

Zou M, Chen Y, Zheng Z, Sheng S, Jia Y, Wang X, Ren S, Yang Y, Li X, Dong W, Guan M, Zhang Q, Xue Y
Frontiers in pharmacology 2021;12:741087

Fibronectin enhances tumor metastasis through B7-H3 in clear cell renal cell carcinoma.

Xie J, Sun M, Zhang D, Chen C, Lin S, Zhang G
FEBS open bio 2021 Nov;11(11):2977-2987

SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.

Zhang F, Zhou X, Zou H, Liu L, Li X, Ruan Y, Xie Y, Shi M, Xiao Y, Wang Y, Zhou Y, Wu Y, Guo B
Experimental cell research 2021 Nov 1;408(1):112856

Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-βRI/Smad Signaling.

Luo X, Deng Q, Xue Y, Zhang T, Wu Z, Peng H, Xuan L, Pan G
Molecules (Basel, Switzerland) 2021 Mar 19;26(6)

Downregulation of ARMC8 promotes tumorigenesis through activating Wnt/β-catenin pathway and EMT in cutaneous squamous cell carcinomas.

Li X, Zhang C, Yuan Y, Wang Y, Lu S, Zhou Z, Zhen P, Zhou M
Journal of dermatological science 2021 Jun;102(3):184-192

Quercetin prevents isoprenaline-induced myocardial fibrosis by promoting autophagy via regulating miR-223-3p/FOXO3.

Hu J, Wang X, Cui X, Kuang W, Li D, Wang J
Cell cycle (Georgetown, Tex.) 2021 Jul;20(13):1253-1269

Differential Angiogenic Potential of 3-Dimension Spheroid of HNSCC Cells in Mouse Xenograft.

Choi SY, Kang SH, Oh SY, Lee KY, Lee HJ, Gum S, Kwon TG, Kim JW, Lee ST, Hong YJ, Kim DG, Hong SH
International journal of molecular sciences 2021 Jul 31;22(15)

Functional role of the long noncoding RNA X-inactive specific transcript in leiomyoma pathogenesis.

Chuang TD, Rehan A, Khorram O
Fertility and sterility 2021 Jan;115(1):238-247

GINS2 promotes EMT in pancreatic cancer via specifically stimulating ERK/MAPK signaling.

Huang L, Chen S, Fan H, Ji D, Chen C, Sheng W
Cancer gene therapy 2021 Aug;28(7-8):839-849

Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats.

Zhao Q, Hao C, Wei J, Huang R, Li C, Yao W
Ecotoxicology and environmental safety 2021 Apr 10;216:112181

Increased Fibronectin Impairs the Function of Excitatory/Inhibitory Synapses in Hirschsprung Disease.

Gao N, Hou P, Wang J, Zhou T, Wang D, Zhang Q, Mu W, Lv X, Li A
Cellular and molecular neurobiology 2020 May;40(4):617-628

LTBP1 promotes esophageal squamous cell carcinoma progression through epithelial-mesenchymal transition and cancer-associated fibroblasts transformation.

Cai R, Wang P, Zhao X, Lu X, Deng R, Wang X, Su Z, Hong C, Lin J
Journal of translational medicine 2020 Mar 26;18(1):139

High expression of fibronectin 1 indicates poor prognosis in gastric cancer.

Sun Y, Zhao C, Ye Y, Wang Z, He Y, Li Y, Mao H
Oncology letters 2020 Jan;19(1):93-102

Olmesartan Medoxomil, An Angiotensin II-Receptor Blocker, Ameliorates Renal Injury In db/db Mice.

Zhu Y, Li ZL, Ding A, Yang H, Zhu WP, Cui TX, Zhang HT, Zhang H
Drug design, development and therapy 2019;13:3657-3667

Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.

Yang Y, Chen S, Tao L, Gan S, Luo H, Xu Y, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388

Angiopoietin-like protein 1 inhibits epithelial to mesenchymal transition in colorectal cancer cells via suppress Slug expression.

Fan H, Huang L, Zhuang X, Ai F, Sun W
Cytotechnology 2019 Feb;71(1):35-44

Fibronectin Facilitates Enterovirus 71 Infection by Mediating Viral Entry.

He QQ, Ren S, Xia ZC, Cheng ZK, Peng NF, Zhu Y
Journal of virology 2018 May 1;92(9)

Propranolol prevents liver cirrhosis by inhibiting hepatic stellate cell activation mediated by the PDGFR/Akt pathway.

Ding Q, Li Z, Liu B, Ling L, Tian X, Zhang C
Human pathology 2018 Jun;76:37-46

Downregulation of FOXP2 promotes breast cancer migration and invasion through TGFβ/SMAD signaling pathway.

Chen MT, Sun HF, Li LD, Zhao Y, Yang LP, Gao SP, Jin W
Oncology letters 2018 Jun;15(6):8582-8588

Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase.

Li Z, Ding Q, Ling LP, Wu Y, Meng DX, Li X, Zhang CQ
World journal of gastroenterology 2018 Feb 21;24(7):819-832

Hepatitis B Virus Stimulated Fibronectin Facilitates Viral Maintenance and Replication through Two Distinct Mechanisms.

Ren S, Wang J, Chen TL, Li HY, Wan YS, Peng NF, Gui XE, Zhu Y
PloS one 2016;11(3):e0152721

Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice.

Zhang Z, Zhang D, Dou M, Li Z, Zhang J, Zhao X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1350-1358

Down-Regulation of NDUFB9 Promotes Breast Cancer Cell Proliferation, Metastasis by Mediating Mitochondrial Metabolism.

Li LD, Sun HF, Liu XX, Gao SP, Jiang HL, Hu X, Jin W
PloS one 2015;10(12):e0144441

No comments: Submit comment

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The Fibronectin antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human Fibronectin. This antibody recognizes human antigen. The Fibronectin antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 66042-1-Ig.pdf

: Show more