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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
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- Product number
- ABIN1882106 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Tumor Protein P53 (TP53) (Sumoylation Site), (AA 364-393) antibody
- Antibody type
- Polyclonal
- Antigen
- This p53 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from human p53.
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Sumoylation Site,AA 364-393
- Antibody clone number
- RB2571
- Vial size
- 400 μL
- Concentration
- 2 mg/mL
Submitted references MDM2-ARF complex regulates p53 sumoylation.
SUMO-1 and p53.
c-Jun and p53 activity is modulated by SUMO-1 modification.
Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.
SUMO-1 modification activates the transcriptional response of p53.
Chen L, Chen J
Oncogene 2003 Aug 14;22(34):5348-57
Oncogene 2003 Aug 14;22(34):5348-57
SUMO-1 and p53.
Melchior F, Hengst L
Cell cycle (Georgetown, Tex.) 2002 Jul-Aug;1(4):245-9
Cell cycle (Georgetown, Tex.) 2002 Jul-Aug;1(4):245-9
c-Jun and p53 activity is modulated by SUMO-1 modification.
Muller S, Berger M, Lehembre F, Seeler JS, Haupt Y, Dejean A
The Journal of biological chemistry 2000 May 5;275(18):13321-9
The Journal of biological chemistry 2000 May 5;275(18):13321-9
Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.
Gostissa M, Hengstermann A, Fogal V, Sandy P, Schwarz SE, Scheffner M, Del Sal G
The EMBO journal 1999 Nov 15;18(22):6462-71
The EMBO journal 1999 Nov 15;18(22):6462-71
SUMO-1 modification activates the transcriptional response of p53.
Rodriguez MS, Desterro JM, Lain S, Midgley CA, Lane DP, Hay RT
The EMBO journal 1999 Nov 15;18(22):6455-61
The EMBO journal 1999 Nov 15;18(22):6455-61
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- TP53 Antibody (C-term) (ABIN1882106) western blot analysis in 293 cell line lysates (35 μg/lane). This demonstrates the TP53 antibody detected the TP53 protein (arrow).
