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- Antibody Data
- Antigen structure
- References [22]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- V2282 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- p53 Antibody N-terminus
- Antibody type
- Monoclonal
- Antigen
- Recombinant human wild-type p53 protein was used as the immunogen for this antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- BP53-12
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the p53 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Direct relationship between the level of p53 stabilization induced by rRNA synthesis-inhibiting drugs and the cell ribosome biogenesis rate.
CASP9 Germline Mutation in a Family with Multiple Brain Tumors.
Anti-proliferative activity of the NPM1 interacting natural product avrainvillamide in acute myeloid leukemia.
Lysosomotropic cationic drugs induce cytostatic and cytotoxic effects: Role of liposolubility and autophagic flux and antagonism by cholesterol ablation.
Hsp70 and p53 expressions and behavior of juvenile pompano, Trachinotus carolinus (Perciformes, Carangidae), at controlled temperature increase
Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58).
p53 Immunohistochemistry as a biomarker of dysplasia and neoplastic progression in Barrett's oesophagus
Oral squamous cell carcinoma associated with proliferative verrucous leukoplakia compared with conventional squamous cell carcinoma--a clinical, histologic and immunohistochemical study.
Anti-tumor effect of Cordyceps militaris in HCV-infected human hepatocarcinoma 7.5 cells.
Ex vivo Efficacy of Anti-Cancer Drug PNC-27 in the Treatment of Patient-Derived Epithelial Ovarian Cancer.
Role of ribophorin II in the response to anticancer drugs in gastric cancer cell lines.
Antitumor effects of a sirtuin inhibitor, tenovin-6, against gastric cancer cells via death receptor 5 up-regulation.
MDM4 expression as an indicator of TP53 reactivation by combined targeting of MDM2 and MDM4 in cancer cells without TP53 mutation.
2-Phenylethynesulfonamide (PES) uncovers a necrotic process regulated by oxidative stress and p53.
High concentrations of glucose suppress etoposide-induced cell death of B-cell lymphoma through BCL-6.
LKB1 loss by alteration of the NKX2-1/p53 pathway promotes tumor malignancy and predicts poor survival and relapse in lung adenocarcinomas.
Combination of CK20 and Ki-67 immunostaining analysis predicts recurrence, progression, and cancer-specific survival in pT1 urothelial bladder cancer.
Apoptotic pathway induced by diallyl trisulfide in pancreatic cancer cells.
Interleukin 6 downregulates p53 expression and activity by stimulating ribosome biogenesis: a new pathway connecting inflammation to cancer.
Clinical, pathological, and molecular aspects of recurrent versus primary pterygium
Immunohistochemical Detection of p53 Tumor Suppressor Protein in Round Cell Tumors of Dogs in Grenada, West Indies
Phytic acid decreases deoxynivalenol and fumonisin B1-induced changes on swine jejunal explants
Scala F, Brighenti E, Govoni M, Imbrogno E, Fornari F, Treré D, Montanaro L, Derenzini M
Oncogene 2016 Feb 25;35(8):977-89
Oncogene 2016 Feb 25;35(8):977-89
CASP9 Germline Mutation in a Family with Multiple Brain Tumors.
Ronellenfitsch MW, Ji Eun O, Satomi K, Sumi K, Harter PN, Steinbach JP, Felsberg J, Capper D, Voegele C, Durand G, McKay J, Le Calvez-Kelm F, Schittenhelm J, Klink B, Mittelbronn M, Ohgaki H
Brain pathology (Zurich, Switzerland) 2016 Dec 9;
Brain pathology (Zurich, Switzerland) 2016 Dec 9;
Anti-proliferative activity of the NPM1 interacting natural product avrainvillamide in acute myeloid leukemia.
Andresen V, Erikstein BS, Mukherjee H, Sulen A, Popa M, Sørnes S, Reikvam H, Chan KP, Hovland R, McCormack E, Bruserud Ø, Myers AG, Gjertsen BT
Cell death & disease 2016 Dec 1;7(12):e2497
Cell death & disease 2016 Dec 1;7(12):e2497
Lysosomotropic cationic drugs induce cytostatic and cytotoxic effects: Role of liposolubility and autophagic flux and antagonism by cholesterol ablation.
Parks A, Marceau F
Toxicology and applied pharmacology 2016 Aug 15;305:55-65
Toxicology and applied pharmacology 2016 Aug 15;305:55-65
Hsp70 and p53 expressions and behavior of juvenile pompano, Trachinotus carolinus (Perciformes, Carangidae), at controlled temperature increase
Cardoso C, Sartorio P, Machado A, Vignardi C, Rojas D, Passos M, Rocha A, Van Ngan P, Gomes V
Journal of Experimental Marine Biology and Ecology 2015 September;470
Journal of Experimental Marine Biology and Ecology 2015 September;470
Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58).
Yang CP, Chiang CW, Chen CH, Lee YC, Wu MH, Tsou YH, Yang YS, Chang WC, Lin DY
Journal of biomedical science 2015 May 16;22:33
Journal of biomedical science 2015 May 16;22:33
p53 Immunohistochemistry as a biomarker of dysplasia and neoplastic progression in Barrett's oesophagus
Kaye P
Diagnostic Histopathology 2015 March;21(3):89-98
Diagnostic Histopathology 2015 March;21(3):89-98
Oral squamous cell carcinoma associated with proliferative verrucous leukoplakia compared with conventional squamous cell carcinoma--a clinical, histologic and immunohistochemical study.
Akrish S, Ben-Izhak O, Sabo E, Rachmiel A
Oral surgery, oral medicine, oral pathology and oral radiology 2015 Mar;119(3):318-25
Oral surgery, oral medicine, oral pathology and oral radiology 2015 Mar;119(3):318-25
Anti-tumor effect of Cordyceps militaris in HCV-infected human hepatocarcinoma 7.5 cells.
Lee S, Lee HH, Kim J, Jung J, Moon A, Jeong CS, Kang H, Cho H
Journal of microbiology (Seoul, Korea) 2015 Jul;53(7):468-74
Journal of microbiology (Seoul, Korea) 2015 Jul;53(7):468-74
Ex vivo Efficacy of Anti-Cancer Drug PNC-27 in the Treatment of Patient-Derived Epithelial Ovarian Cancer.
Sarafraz-Yazdi E, Gorelick C, Wagreich AR, Salame G, Angert M, Gartman CH, Gupta V, Bowne WB, Lee YC, Abulafia O, Pincus MR, Michl J
Annals of clinical and laboratory science 2015 Fall;45(6):650-8
Annals of clinical and laboratory science 2015 Fall;45(6):650-8
Role of ribophorin II in the response to anticancer drugs in gastric cancer cell lines.
Yuan TM, Liang RY, Chueh PJ, Chuang SM
Oncology letters 2015 Apr;9(4):1861-1868
Oncology letters 2015 Apr;9(4):1861-1868
Antitumor effects of a sirtuin inhibitor, tenovin-6, against gastric cancer cells via death receptor 5 up-regulation.
Hirai S, Endo S, Saito R, Hirose M, Ueno T, Suzuki H, Yamato K, Abei M, Hyodo I
PloS one 2014;9(7):e102831
PloS one 2014;9(7):e102831
MDM4 expression as an indicator of TP53 reactivation by combined targeting of MDM2 and MDM4 in cancer cells without TP53 mutation.
Hirose M, Yamato K, Endo S, Saito R, Ueno T, Hirai S, Suzuki H, Abei M, Natori Y, Hyodo I
Oncoscience 2014;1(12):830-43
Oncoscience 2014;1(12):830-43
2-Phenylethynesulfonamide (PES) uncovers a necrotic process regulated by oxidative stress and p53.
Mattiolo P, Barbero-Farran A, Yuste VJ, Boix J, Ribas J
Biochemical pharmacology 2014 Oct 1;91(3):301-11
Biochemical pharmacology 2014 Oct 1;91(3):301-11
High concentrations of glucose suppress etoposide-induced cell death of B-cell lymphoma through BCL-6.
Shao Y, Ling CC, Liu XQ
Biochemical and biophysical research communications 2014 Jul 18;450(1):227-33
Biochemical and biophysical research communications 2014 Jul 18;450(1):227-33
LKB1 loss by alteration of the NKX2-1/p53 pathway promotes tumor malignancy and predicts poor survival and relapse in lung adenocarcinomas.
Tsai LH, Chen PM, Cheng YW, Chen CY, Sheu GT, Wu TC, Lee H
Oncogene 2014 Jul 17;33(29):3851-60
Oncogene 2014 Jul 17;33(29):3851-60
Combination of CK20 and Ki-67 immunostaining analysis predicts recurrence, progression, and cancer-specific survival in pT1 urothelial bladder cancer.
Bertz S, Otto W, Denzinger S, Wieland WF, Burger M, Stöhr R, Link S, Hofstädter F, Hartmann A
European urology 2014 Jan;65(1):218-26
European urology 2014 Jan;65(1):218-26
Apoptotic pathway induced by diallyl trisulfide in pancreatic cancer cells.
Ma HB, Huang S, Yin XR, Zhang Y, Di ZL
World journal of gastroenterology 2014 Jan 7;20(1):193-203
World journal of gastroenterology 2014 Jan 7;20(1):193-203
Interleukin 6 downregulates p53 expression and activity by stimulating ribosome biogenesis: a new pathway connecting inflammation to cancer.
Brighenti E, Calabrese C, Liguori G, Giannone FA, Trerè D, Montanaro L, Derenzini M
Oncogene 2014 Aug 28;33(35):4396-406
Oncogene 2014 Aug 28;33(35):4396-406
Clinical, pathological, and molecular aspects of recurrent versus primary pterygium
Shebl A, Nassar M, El-Sebaey A, Abdel-Rahman M, El-Ghonemy K
Menoufia Medical Journal 2014 ;27(2):386
Menoufia Medical Journal 2014 ;27(2):386
Immunohistochemical Detection of p53 Tumor Suppressor Protein in Round Cell Tumors of Dogs in Grenada, West Indies
Tiwari K
Advances in Animal and Veterinary Sciences 2014 ;2(3S):23-27
Advances in Animal and Veterinary Sciences 2014 ;2(3S):23-27
Phytic acid decreases deoxynivalenol and fumonisin B1-induced changes on swine jejunal explants
da Silva E, Gerez J, do Carmo Drape T, Bracarense A
Toxicology Reports 2014 ;1
Toxicology Reports 2014 ;1
No comments: Submit comment
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- Western blot testing of human samples with p53 antibody (BP53-12).
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC staining of human colon carcinoma with p53 antibody (BP53-12).
