Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362056 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Tumor Protein P53 (TP53) (pSer46) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pSer46 (M-L-S (p) -P-D) derived from Human p53. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer46
- Isotype
- IgG
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified.
HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage.
Ultraviolet irradiation-induced K(+) channel activity involving p53 activation in corneal epithelial cells.
A decade of CDK5.
p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway.
Mayo LD, Seo YR, Jackson MW, Smith ML, Rivera Guzman J, Korgaonkar CK, Donner DB
The Journal of biological chemistry 2005 Jul 15;280(28):25953-9
The Journal of biological chemistry 2005 Jul 15;280(28):25953-9
HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage.
Di Stefano V, Soddu S, Sacchi A, D'Orazi G
Oncogene 2005 Aug 18;24(35):5431-42
Oncogene 2005 Aug 18;24(35):5431-42
Ultraviolet irradiation-induced K(+) channel activity involving p53 activation in corneal epithelial cells.
Wang L, Dai W, Lu L
Oncogene 2005 Apr 21;24(18):3020-7
Oncogene 2005 Apr 21;24(18):3020-7
A decade of CDK5.
Dhavan R, Tsai LH
Nature reviews. Molecular cell biology 2001 Oct;2(10):749-59
Nature reviews. Molecular cell biology 2001 Oct;2(10):749-59
p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway.
Patrick GN, Zhou P, Kwon YT, Howley PM, Tsai LH
The Journal of biological chemistry 1998 Sep 11;273(37):24057-64
The Journal of biological chemistry 1998 Sep 11;273(37):24057-64
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