ABIN966756

antibody from antibodies-online

Targeting: TP53 LFS1, p53

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966756

Provider

antibodies-online

Product name

anti-Tumor Protein P53 (TP53) (pSer315) antibody

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human p53 around the phosphorylation site of serine 315 (S-S-SP-P-Q).

Reactivity

Human

Host

Rabbit

Vial size

100ug

Concentration

100ug/100ul.

Storage

Store at -20°C/1 year.

References

Submitted references

Site-specific phosphorylation of human p53 protein determined by mass spectrometry.

Merrick BA, Zhou W, Martin KJ, Jeyarajah S, Parker CE, Selkirk JK, Tomer KB, Borchers CH
Biochemistry 2001 Apr 3;40(13):4053-66

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The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro.

Lu H, Fisher RP, Bailey P, Levine AJ
Molecular and cellular biology 1997 Oct;17(10):5923-34

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Differential effects of phosphorylation of rat p53 on transactivation of promoters derived from different p53 responsive genes.

Lohrum M, Scheidtmann KH
Oncogene 1996 Dec 19;13(12):2527-39

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Phosphorylation at Ser-15 and Ser-392 in mutant p53 molecules from human tumors is altered compared to wild-type p53.

Ullrich SJ, Sakaguchi K, Lees-Miller SP, Fiscella M, Mercer WE, Anderson CW, Appella E
Proceedings of the National Academy of Sciences of the United States of America 1993 Jul 1;90(13):5954-8