orb67279

antibody from Biorbyt

Targeting: ARRB1 ARR1

Western blot (Data presented on provider website)

Antibody Data

Product number

orb67279

Provider

Biorbyt

Product name

ARRB1 antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal to ARRB1.Beta-arrestin-1 (ARRB1) is a cytosolic protein that belongs to the arrestin family. Beta arrestinsfunction in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediatingboth receptor desensitization and resensitization processes. It is involved in IL8-mediated granulerelease in neutrophils. Beta-arrestin-1 acts as a cofactor in the beta-adrenergic receptor kinase(BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, itis expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system isbelieved to play a major role in regulating receptor-mediated immune functions.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Vial size

100 ul

Storage

-20°C