DCABH-2466

antibody from Creative Diagnostics

Targeting: ARRB1 ARR1

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

DCABH-2466

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABH-2466, RRID:AB_2476370

Product name

Anti-ARRB1 monoclonal antibody, clone 2I5-G6-D22

Antibody type

Monoclonal

Description

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones,neurotransmitters, or sensory signals.Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors.Besides the central nervous system,it is expressed at high levels in peripheral blood leukocytes,and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions.Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2I5-G6-D22

Storage

Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.