BS7690

antibody from Bioworld Technology, Inc
Targeting: IDS ID2S, SIDS
Provider product page for BS7690
Western blot
Immunohistochemistry

Antibody data

Product number
BS7690 - Provider product page
Provider
Bioworld Technology, Inc
Product name
IDS polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human IDS.
Description
IDS (Iduronate 2-sulfatase), also known as SIDS, is a 550 amino acid protein that localizes to the lysosome and belongs to the sulfatase family. Expressed in lung, liver, kidney and placenta, IDS uses calcium as a cofactor to catalyze the hydrolysis of select sulfate groups on dermatan sulfate, heparan sulfate and heparin and, via this catalytic activity, is essential for the lysosomal degradation of both dermatan and heparan sulfate. Defects in the gene encoding IDS are the cause of mucopolysaccharidosis type 2 (MPS2), more commonly known as Hunter syndrome, which is characterized by skeletal deformities, hepatosplenomegaly and progressive cardiopulmonary deterioration, as well as neurological damage and, in some cases, death. IDS exists as two alternatively spliced isoforms, designated long and short.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
IDS protein structure - BS7690 shown in red.