Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [71]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 17984-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17984-1-AP, RRID:AB_2224539
- Product name
- AIF antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated AIF antibody (Cat. #17984-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Intracerebroventricular infusion of secretoneurin inhibits neuronal NLRP3-Apoptosis pathway and preserves learning and memory after cerebral ischemia.
LC-MS based metabonomics study on protective mechanism of ESWW in cerebral ischemia via CYTC/Apaf-1/NDRG4 pathway.
RIPK3 activation promotes DAXX-dependent neuronal necroptosis after intracerebral hemorrhage in mice.
Multifunctional Fe-based coordination polymer nano-bomb modified with β-lapachone and CaO(2) for targeted tumor dual chemodynamic therapy with enhanced ferroptosis and H(2)O(2) self-supply.
Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis.
Pimpinellin ameliorates macrophage inflammation by promoting RNF146-mediated PARP1 ubiquitination.
Formononetin alleviates cerebral ischemia-reperfusion injury in rats by targeting the PARP-1/PARG/Iduna signaling pathway.
A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress.
Comprehensive evaluation of cell death-related genes as novel diagnostic biomarkers for breast cancer.
4-Octyl itaconate inhibits inflammation to attenuate psoriasis as an agonist of oxeiptosis.
LACTB induces cancer cell death through the activation of the intrinsic caspase-independent pathway in breast cancer.
A Missense Variant in AIFM1 Caused Mitochondrial Dysfunction and Intolerance to Riboflavin Deficiency.
Downregulation of hepatic METTL3 contributes to APAP-induced liver injury in mice.
SERD-NHC-Au(I) complexes for dual targeting ER and TrxR to induce ICD in breast cancer.
Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis.
Knockout of IL-6 mitigates cold water-immersion restraint stress-induced intestinal epithelial injury and apoptosis.
Aloe-Emodin Induces Mitochondrial Dysfunction and Pyroptosis by Activation of the Caspase-9/3/Gasdermin E Axis in HeLa Cells.
Sevoflurane exposure during the second trimester induces neurotoxicity in offspring rats by hyperactivation of PARP-1.
Diterpenoids from the whole plant of Euphorbia wallichii and their protective effects on H(2)O(2)-induced BV-2 microglial cells injury.
Mitochondrial Glrx2 Knockout Augments Acetaminophen-Induced Hepatotoxicity in Mice.
Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways.
miRNA-27a Transcription Activated by c-Fos Regulates Myocardial Ischemia-Reperfusion Injury by Targeting ATAD3a.
Calcitriol Alleviates MPP(+)- and MPTP-Induced Parthanatos Through the VDR/PARP1 Pathway in the Model of Parkinson's Disease.
Quercitrin Attenuates Acetaminophen-Induced Acute Liver Injury by Maintaining Mitochondrial Complex I Activity.
Clusterin inhibits Cr(VI)-induced apoptosis via enhancing mitochondrial biogenesis through AKT-associated STAT3 activation in L02 hepatocytes.
Diosgenin exerts anti-tumor effects through inactivation of cAMP/PKA/CREB signaling pathway in colorectal cancer.
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.
Swainsonine promotes apoptosis by impairing lysosomal function and inhibiting autophagic degradation in rat primary renal tubular epithelial cells.
Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca(2+) Homeostasis, and Bcl2 Expression.
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
RIP3 facilitates necroptosis through CaMKII and AIF after intracerebral hemorrhage in mice.
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Dose- and Time-Dependent Cytotoxicity of Carteolol in Corneal Endothelial Cells and the Underlying Mechanisms.
Selenoprotein T protects against cisplatin-induced acute kidney injury through suppression of oxidative stress and apoptosis.
Regulation of JNK signaling pathway and RIPK3/AIF in necroptosis-mediated global cerebral ischemia/reperfusion injury in rats.
The renoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy.
Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo.
Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.
Insights into mechanisms of pranoprofen-induced apoptosis and necroptosis in human corneal stromal cells.
Tongmai formula improves cardiac function via regulating mitochondrial quality control in the myocardium with ischemia/reperfusion injury.
Norfloxacin induces apoptosis and necroptosis in human corneal epithelial cells.
Blocking Parkin/PINK1-mediated mitophagy sensitizes hepatocellular carcinoma cells to sanguinarine-induced mitochondrial apoptosis.
Estrogen receptors participate in silibinin-caused nuclear translocation of apoptosis-inducing factor in human breast cancer MCF-7 cells.
Oxidized Perilla and Linseed Oils Induce Neuronal Apoptosis by Caspase-Dependent and -Independent Pathways.
RAD6B Plays a Critical Role in Neuronal DNA Damage Response to Resist Neurodegeneration.
Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells.
NEDD4 protects vascular endothelial cells against Angiotensin II-induced cell death via enhancement of XPO1-mediated nuclear export.
Selective Serotonin Reuptake Inhibitors Aggravate Depression-Associated Dry Eye Via Activating the NF-κB Pathway.
Proteomics Analysis of Tangeretin-Induced Apoptosis through Mitochondrial Dysfunction in Bladder Cancer Cells.
Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.
XPO1-mediated nuclear export of RNF146 protects from angiotensin II-induced endothelial cellular injury.
Polybrominated Diphenyl Ethers Quinone Induced Parthanatos-like Cell Death through a Reactive Oxygen Species-Associated Poly(ADP-ribose) Polymerase 1 Signaling.
Alisol B-23-acetate, a tetracyclic triterpenoid isolated from Alisma orientale, induces apoptosis in human lung cancer cells via the mitochondrial pathway.
Supplementary choline attenuates olive oil lipid emulsion-induced enterocyte apoptosis through suppression of CELF1/AIF pathway.
Cognitive-enhancing effect of polysaccharides from Flammulina velutipes on Alzheimer's disease by compatibilizing with ginsenosides.
Quantitative proteomics in Friedreich's ataxia B-lymphocytes: A valuable approach to decipher the biochemical events responsible for pathogenesis.
Olive Oil-Supplemented Lipid Emulsion Induces CELF1 Expression and Promotes Apoptosis in Caco-2 Cells.
Capsular Polysaccharide of Mycoplasma ovipneumoniae Induces Sheep Airway Epithelial Cell Apoptosis via ROS-Dependent JNK/P38 MAPK Pathways.
Dehydrobruceine B enhances the cisplatin-induced cytotoxicity through regulation of the mitochondrial apoptotic pathway in lung cancer A549 cells.
Bone marrow mesenchymal stem cells repair cadmium-induced rat testis injury by inhibiting mitochondrial apoptosis.
Sox2 inhibits Wnt-β-catenin signaling and metastatic potency of cisplatin-resistant lung adenocarcinoma cells.
GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation.
Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway.
Nitro-oleic acid attenuates OGD/R-triggered apoptosis in renal tubular cells via inhibition of Bax mitochondrial translocation in a PPAR-γ-dependent manner.
O-Alkylated derivatives of quercetin induce apoptosis of MCF-7 cells via a caspase-independent mitochondrial pathway.
Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549.
Induction of apoptosis in infantile hemangioma endothelial cells by propranolol.
Proteomic analysis of mitochondria from infantile hemangioma endothelial cells treated with sodium morrhuate and its liposomal formulation.
Characterization of 9-nitrocamptothecin liposomes: anticancer properties and mechanisms on hepatocellular carcinoma in vitro and in vivo.
Gu C, Kang X, Chen X, Sun Y, Li X
Neurochemistry international 2024 Sep;178:105770
Neurochemistry international 2024 Sep;178:105770
LC-MS based metabonomics study on protective mechanism of ESWW in cerebral ischemia via CYTC/Apaf-1/NDRG4 pathway.
Liang Y, Wang F, Song Y, Tang C, Wu R, Feng Q, Han M, Li Y, Chen W, Zhang J, Jiang M, Wang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155543
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155543
RIPK3 activation promotes DAXX-dependent neuronal necroptosis after intracerebral hemorrhage in mice.
Bai Q, Wang S, Rao D, Zhou Z, Wang J, Wang Q, Qin Y, Chu Z, Zhao S, Yu D, Xu Y
CNS neuroscience & therapeutics 2024 Jan;30(1):e14397
CNS neuroscience & therapeutics 2024 Jan;30(1):e14397
Multifunctional Fe-based coordination polymer nano-bomb modified with β-lapachone and CaO(2) for targeted tumor dual chemodynamic therapy with enhanced ferroptosis and H(2)O(2) self-supply.
Zhao P, Gong L, Chang L, Du H, Geng M, Meng S, Dai L
Journal of nanobiotechnology 2024 Jan 3;22(1):3
Journal of nanobiotechnology 2024 Jan 3;22(1):3
Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis.
Yang X, Gu C, Cai J, Li F, He X, Luo L, Xiao W, Hu B, Hu J, Qian H, Ren S, Zhang L, Zhu X, Yang L, Yang J, Yang Z, Zheng Y, Huang X, Wang Z
Redox biology 2024 Feb;69:103002
Redox biology 2024 Feb;69:103002
Pimpinellin ameliorates macrophage inflammation by promoting RNF146-mediated PARP1 ubiquitination.
Yang L, Du M, Liu K, Wang P, Zhu J, Li F, Wang Z, Huang K, Liang M
Phytotherapy research : PTR 2024 Apr;38(4):1783-1798
Phytotherapy research : PTR 2024 Apr;38(4):1783-1798
Formononetin alleviates cerebral ischemia-reperfusion injury in rats by targeting the PARP-1/PARG/Iduna signaling pathway.
Luo J, Cai Y, Wei D, Cao L, He Q, Wu Y
Brain research 2024 Apr 15;1829:148845
Brain research 2024 Apr 15;1829:148845
A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress.
Jiang W, Zhang M, Gao C, Yan C, Gao R, He Z, Wei X, Xiong J, Ruan Z, Yang Q, Li J, Li Q, Zhong Z, Zhang M, Yuan Q, Hu H, Wang S, Hu MM, Cai C, Wu GS, Jiang C, Zhang YL, Zhang CS, Zhang J
The EMBO journal 2023 Oct 16;42(20):e113743
The EMBO journal 2023 Oct 16;42(20):e113743
Comprehensive evaluation of cell death-related genes as novel diagnostic biomarkers for breast cancer.
Shi X, Ding H, Tao J, Zhu Y, Zhang X, He G, Yang J, Wu X, Liu X, Yu X
Heliyon 2023 Nov;9(11):e21341
Heliyon 2023 Nov;9(11):e21341
4-Octyl itaconate inhibits inflammation to attenuate psoriasis as an agonist of oxeiptosis.
You M, Jiang Q, Huang H, Ma F, Zhou X
International immunopharmacology 2023 Nov;124(Pt B):110915
International immunopharmacology 2023 Nov;124(Pt B):110915
LACTB induces cancer cell death through the activation of the intrinsic caspase-independent pathway in breast cancer.
Gonzalez-Morena JM, Escudeiro-Lopes S, Ferreira-Mendes JM, Jakoube P, Cutano V, Vinaixa-Forner J, Kralova Viziova P, Hartmanova A, Sedlacek R, Machado S, Malcekova B, Keckesova Z
Apoptosis : an international journal on programmed cell death 2023 Feb;28(1-2):186-198
Apoptosis : an international journal on programmed cell death 2023 Feb;28(1-2):186-198
A Missense Variant in AIFM1 Caused Mitochondrial Dysfunction and Intolerance to Riboflavin Deficiency.
Zhao Y, Lin Y, Wang B, Liu F, Zhao D, Wang W, Ren H, Wang J, Xu Z, Yan C, Ji K
Neuromolecular medicine 2023 Dec;25(4):489-500
Neuromolecular medicine 2023 Dec;25(4):489-500
Downregulation of hepatic METTL3 contributes to APAP-induced liver injury in mice.
Liu C, Li X, Gao M, Dong Y, Chen Z
JHEP reports : innovation in hepatology 2023 Aug;5(8):100766
JHEP reports : innovation in hepatology 2023 Aug;5(8):100766
SERD-NHC-Au(I) complexes for dual targeting ER and TrxR to induce ICD in breast cancer.
Lu Y, Sheng X, Liu C, Liang Z, Wang X, Liu L, Wen Z, Yang Z, Du Q, Liu W
Pharmacological research 2023 Apr;190:106731
Pharmacological research 2023 Apr;190:106731
Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis.
Ji W, Zhang L, Ma C, Xu X, Li S, Xia H, Zhou W, Liu X
Cell reports 2023 Apr 25;42(4):112327
Cell reports 2023 Apr 25;42(4):112327
Knockout of IL-6 mitigates cold water-immersion restraint stress-induced intestinal epithelial injury and apoptosis.
Zhang Y, Duan C, Wu S, Ma J, Liu Y, Li W, Wang T, Yang L, Cheng K, Zhuang R
Frontiers in immunology 2022;13:936689
Frontiers in immunology 2022;13:936689
Aloe-Emodin Induces Mitochondrial Dysfunction and Pyroptosis by Activation of the Caspase-9/3/Gasdermin E Axis in HeLa Cells.
Li T, Shi L, Liu W, Hu X, Hui Y, Di M, Xue S, Zheng Y, Yao M, Li C, Meng K
Frontiers in pharmacology 2022;13:854526
Frontiers in pharmacology 2022;13:854526
Sevoflurane exposure during the second trimester induces neurotoxicity in offspring rats by hyperactivation of PARP-1.
Wang C, Jiang Q, Zhao P
Psychopharmacology 2022 Sep;239(9):3031-3045
Psychopharmacology 2022 Sep;239(9):3031-3045
Diterpenoids from the whole plant of Euphorbia wallichii and their protective effects on H(2)O(2)-induced BV-2 microglial cells injury.
Wang Y, Zhu M, Liang J, Zhang N, Sun D, Li H, Chen L
Bioorganic chemistry 2022 Nov;128:106067
Bioorganic chemistry 2022 Nov;128:106067
Mitochondrial Glrx2 Knockout Augments Acetaminophen-Induced Hepatotoxicity in Mice.
Li J, Tang X, Wen X, Ren X, Zhang H, Du Y, Lu J
Antioxidants (Basel, Switzerland) 2022 Aug 24;11(9)
Antioxidants (Basel, Switzerland) 2022 Aug 24;11(9)
Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways.
Hu Z, Wang H, Fu Y, Ma K, Ma X, Wang J
Nutrition and cancer 2021;73(8):1459-1470
Nutrition and cancer 2021;73(8):1459-1470
miRNA-27a Transcription Activated by c-Fos Regulates Myocardial Ischemia-Reperfusion Injury by Targeting ATAD3a.
Bao Y, Qiao Y, Yu H, Zhang Z, Yang H, Xin X, Chen Y, Guo Y, Wu N, Jia D
Oxidative medicine and cellular longevity 2021;2021:2514947
Oxidative medicine and cellular longevity 2021;2021:2514947
Calcitriol Alleviates MPP(+)- and MPTP-Induced Parthanatos Through the VDR/PARP1 Pathway in the Model of Parkinson's Disease.
Hu J, Wu J, Wan F, Kou L, Yin S, Sun Y, Li Y, Zhou Q, Wang T
Frontiers in aging neuroscience 2021;13:657095
Frontiers in aging neuroscience 2021;13:657095
Quercitrin Attenuates Acetaminophen-Induced Acute Liver Injury by Maintaining Mitochondrial Complex I Activity.
Xiong W, Yuan Z, Wang T, Wu S, Xiong Y, Yao Y, Yang Y, Wu H
Frontiers in pharmacology 2021;12:586010
Frontiers in pharmacology 2021;12:586010
Clusterin inhibits Cr(VI)-induced apoptosis via enhancing mitochondrial biogenesis through AKT-associated STAT3 activation in L02 hepatocytes.
Liang N, Li S, Liang Y, Ma Y, Tang S, Ye S, Xiao F
Ecotoxicology and environmental safety 2021 Sep 15;221:112447
Ecotoxicology and environmental safety 2021 Sep 15;221:112447
Diosgenin exerts anti-tumor effects through inactivation of cAMP/PKA/CREB signaling pathway in colorectal cancer.
Li SY, Shang J, Mao XM, Fan R, Li HQ, Li RH, Shen DY
European journal of pharmacology 2021 Oct 5;908:174370
European journal of pharmacology 2021 Oct 5;908:174370
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Zhao G, Qi L, Wang Y, Li X, Li Q, Tang X, Wang X, Wu C
Ecotoxicology and environmental safety 2021 Oct 1;222:112529
Ecotoxicology and environmental safety 2021 Oct 1;222:112529
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Wang J, Su Q, Wu Q, Chen K, Ullah A, Ghauri MA, Zhang Y
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.
Le Vasseur M, Friedman J, Jost M, Xu J, Yamada J, Kampmann M, Horlbeck MA, Salemi MR, Phinney BS, Weissman JS, Nunnari J
eLife 2021 May 26;10
eLife 2021 May 26;10
Swainsonine promotes apoptosis by impairing lysosomal function and inhibiting autophagic degradation in rat primary renal tubular epithelial cells.
Wang S, Guo R, Su Y, Yang C, Guo Y, Tan C, Zhao B
Chemico-biological interactions 2021 Feb 25;336:109319
Chemico-biological interactions 2021 Feb 25;336:109319
Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca(2+) Homeostasis, and Bcl2 Expression.
Zhong Y, Jin C, Han J, Zhu J, Liu Q, Sun D, Xia X, Zhang Y, Peng X
Molecular nutrition & food research 2021 Aug;65(15):e2001202
Molecular nutrition & food research 2021 Aug;65(15):e2001202
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
Quan X, Song L, Zheng X, Liu S, Ding H, Li S, Xu G, Li X, Liu L
Neuroscience 2021 Apr 15;460:107-119
Neuroscience 2021 Apr 15;460:107-119
RIP3 facilitates necroptosis through CaMKII and AIF after intracerebral hemorrhage in mice.
Xu Y, Wu X, Hu W, Yu D, Shao Z, Li W, Huang T, Zhang J, Zhu X, Li X, Yang H, Chu Z, Lv K
Neuroscience letters 2021 Apr 1;749:135699
Neuroscience letters 2021 Apr 1;749:135699
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Deng X, Liu J, Liu L, Sun X, Huang J, Dong J
International journal of biological sciences 2020;16(8):1403-1416
International journal of biological sciences 2020;16(8):1403-1416
Dose- and Time-Dependent Cytotoxicity of Carteolol in Corneal Endothelial Cells and the Underlying Mechanisms.
Su W, Zhao J, Fan TJ
Frontiers in pharmacology 2020;11:202
Frontiers in pharmacology 2020;11:202
Selenoprotein T protects against cisplatin-induced acute kidney injury through suppression of oxidative stress and apoptosis.
Huang J, Bao D, Lei CT, Tang H, Zhang CY, Su H, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):11983-11996
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):11983-11996
Regulation of JNK signaling pathway and RIPK3/AIF in necroptosis-mediated global cerebral ischemia/reperfusion injury in rats.
Hu W, Wu X, Yu D, Zhao L, Zhu X, Li X, Huang T, Chu Z, Xu Y
Experimental neurology 2020 Sep;331:113374
Experimental neurology 2020 Sep;331:113374
The renoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy.
Jin C, Miao X, Zhong Y, Han J, Liu Q, Zhu J, Xia X, Peng X
Food & function 2020 Sep 23;11(9):7456-7467
Food & function 2020 Sep 23;11(9):7456-7467
Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo.
Liu J, Deng X, Sun X, Dong J, Huang J
Life sciences 2020 Sep 15;257:118040
Life sciences 2020 Sep 15;257:118040
Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.
Shi X, Zhang T, Lou H, Song H, Li C, Fan P
Journal of medicinal chemistry 2020 Oct 22;63(20):11786-11800
Journal of medicinal chemistry 2020 Oct 22;63(20):11786-11800
Insights into mechanisms of pranoprofen-induced apoptosis and necroptosis in human corneal stromal cells.
Lin Y, Yu M, Fan T
Toxicology letters 2020 Mar 1;320:9-18
Toxicology letters 2020 Mar 1;320:9-18
Tongmai formula improves cardiac function via regulating mitochondrial quality control in the myocardium with ischemia/reperfusion injury.
Zhao Y, Guo R, Li L, Li S, Fan G, Zhao X, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110897
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110897
Norfloxacin induces apoptosis and necroptosis in human corneal epithelial cells.
Yang T, Fan TJ, Xu B
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104868
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104868
Blocking Parkin/PINK1-mediated mitophagy sensitizes hepatocellular carcinoma cells to sanguinarine-induced mitochondrial apoptosis.
Su Q, Wang J, Liu F, Zhang Y
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104840
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104840
Estrogen receptors participate in silibinin-caused nuclear translocation of apoptosis-inducing factor in human breast cancer MCF-7 cells.
Liu W, Ji Y, Sun Y, Si L, Fu J, Hayashi T, Onodera S, Ikejima T
Archives of biochemistry and biophysics 2020 Aug 15;689:108458
Archives of biochemistry and biophysics 2020 Aug 15;689:108458
Oxidized Perilla and Linseed Oils Induce Neuronal Apoptosis by Caspase-Dependent and -Independent Pathways.
Ueno Y, Kawamoto Y, Nakane Y, Natsume R, Miura K, Okumura Y, Murate T, Hattori E, Osawa T
Foods (Basel, Switzerland) 2020 Apr 26;9(5)
Foods (Basel, Switzerland) 2020 Apr 26;9(5)
RAD6B Plays a Critical Role in Neuronal DNA Damage Response to Resist Neurodegeneration.
Guo Z, Tian Y, Guo Y, Li B, Liu X, Xie K, Song Y, Wang D
Frontiers in cellular neuroscience 2019;13:392
Frontiers in cellular neuroscience 2019;13:392
Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells.
Yang N, Li C, Li H, Liu M, Cai X, Cao F, Feng Y, Li M, Wang X
Frontiers in pharmacology 2019;10:709
Frontiers in pharmacology 2019;10:709
NEDD4 protects vascular endothelial cells against Angiotensin II-induced cell death via enhancement of XPO1-mediated nuclear export.
Xu J, Sheng Z, Li F, Wang S, Yuan Y, Wang M, Yu Z
Experimental cell research 2019 Oct 1;383(1):111505
Experimental cell research 2019 Oct 1;383(1):111505
Selective Serotonin Reuptake Inhibitors Aggravate Depression-Associated Dry Eye Via Activating the NF-κB Pathway.
Zhang X, Yin Y, Yue L, Gong L
Investigative ophthalmology & visual science 2019 Jan 2;60(1):407-419
Investigative ophthalmology & visual science 2019 Jan 2;60(1):407-419
Proteomics Analysis of Tangeretin-Induced Apoptosis through Mitochondrial Dysfunction in Bladder Cancer Cells.
Lin JJ, Huang CC, Su YL, Luo HL, Lee NL, Sung MT, Wu YJ
International journal of molecular sciences 2019 Feb 26;20(5)
International journal of molecular sciences 2019 Feb 26;20(5)
Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.
Xu H, Li Y, Han B, Li Z, Wang B, Jiang P, Zhang J, Ma W, Zhou D, Li X, Ye X
Journal of agricultural and food chemistry 2018 Sep 19;66(37):9704-9718
Journal of agricultural and food chemistry 2018 Sep 19;66(37):9704-9718
XPO1-mediated nuclear export of RNF146 protects from angiotensin II-induced endothelial cellular injury.
Sheng Z, Xu Y, Wang S, Yuan Y, Huang T, Lu P
Biochemical and biophysical research communications 2018 Sep 10;503(3):1544-1549
Biochemical and biophysical research communications 2018 Sep 10;503(3):1544-1549
Polybrominated Diphenyl Ethers Quinone Induced Parthanatos-like Cell Death through a Reactive Oxygen Species-Associated Poly(ADP-ribose) Polymerase 1 Signaling.
Dong W, Yang B, Wang Y, Yuan J, Fan Y, Song E, Song Y
Chemical research in toxicology 2018 Nov 19;31(11):1164-1171
Chemical research in toxicology 2018 Nov 19;31(11):1164-1171
Alisol B-23-acetate, a tetracyclic triterpenoid isolated from Alisma orientale, induces apoptosis in human lung cancer cells via the mitochondrial pathway.
Wang J, Li H, Wang X, Shen T, Wang S, Ren D
Biochemical and biophysical research communications 2018 Nov 10;505(4):1015-1021
Biochemical and biophysical research communications 2018 Nov 10;505(4):1015-1021
Supplementary choline attenuates olive oil lipid emulsion-induced enterocyte apoptosis through suppression of CELF1/AIF pathway.
Yan JK, Zhu J, Gong ZZ, Wen J, Xiao YT, Zhang T, Cai W
Journal of cellular and molecular medicine 2018 Mar;22(3):1562-1573
Journal of cellular and molecular medicine 2018 Mar;22(3):1562-1573
Cognitive-enhancing effect of polysaccharides from Flammulina velutipes on Alzheimer's disease by compatibilizing with ginsenosides.
Zhang Y, Li H, Yang X, Jin G, Zhang Y
International journal of biological macromolecules 2018 Jun;112:788-795
International journal of biological macromolecules 2018 Jun;112:788-795
Quantitative proteomics in Friedreich's ataxia B-lymphocytes: A valuable approach to decipher the biochemical events responsible for pathogenesis.
Télot L, Rousseau E, Lesuisse E, Garcia C, Morlet B, Léger T, Camadro JM, Serre V
Biochimica et biophysica acta. Molecular basis of disease 2018 Apr;1864(4 Pt A):997-1009
Biochimica et biophysica acta. Molecular basis of disease 2018 Apr;1864(4 Pt A):997-1009
Olive Oil-Supplemented Lipid Emulsion Induces CELF1 Expression and Promotes Apoptosis in Caco-2 Cells.
Yan JK, Zhu J, Gong ZZ, Wen J, Xiao YT, Cai W, Zhang T
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;41(2):711-721
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;41(2):711-721
Capsular Polysaccharide of Mycoplasma ovipneumoniae Induces Sheep Airway Epithelial Cell Apoptosis via ROS-Dependent JNK/P38 MAPK Pathways.
Jiang Z, Song F, Li Y, Xue D, Zhao N, Zhang J, Deng G, Li M, Liu X, Wang Y
Oxidative medicine and cellular longevity 2017;2017:6175841
Oxidative medicine and cellular longevity 2017;2017:6175841
Dehydrobruceine B enhances the cisplatin-induced cytotoxicity through regulation of the mitochondrial apoptotic pathway in lung cancer A549 cells.
Huang Z, Yang G, Shen T, Wang X, Li H, Ren D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:623-631
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 May;89:623-631
Bone marrow mesenchymal stem cells repair cadmium-induced rat testis injury by inhibiting mitochondrial apoptosis.
Wang YJ, Yan J, Zou XL, Guo KJ, Zhao Y, Meng CY, Yin F, Guo L
Chemico-biological interactions 2017 Jun 1;271:39-47
Chemico-biological interactions 2017 Jun 1;271:39-47
Sox2 inhibits Wnt-β-catenin signaling and metastatic potency of cisplatin-resistant lung adenocarcinoma cells.
He J, Shi J, Zhang K, Xue J, Li J, Yang J, Chen J, Wei J, Ren H, Liu X
Molecular medicine reports 2017 Apr;15(4):1693-1701
Molecular medicine reports 2017 Apr;15(4):1693-1701
GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation.
Zhang X, Zhu C, Wang T, Jiang H, Ren Y, Zhang Q, Wu K, Liu F, Liu Y, Wu J
PLoS pathogens 2017 Apr;13(4):e1006321
PLoS pathogens 2017 Apr;13(4):e1006321
Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway.
Zhao L, Wen Q, Yang G, Huang Z, Shen T, Li H, Ren D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2016 Feb 15;23(2):114-22
Phytomedicine : international journal of phytotherapy and phytopharmacology 2016 Feb 15;23(2):114-22
Nitro-oleic acid attenuates OGD/R-triggered apoptosis in renal tubular cells via inhibition of Bax mitochondrial translocation in a PPAR-γ-dependent manner.
Nie H, Xue X, Li J, Liu X, Lv S, Guan G, Liu H, Liu G, Liu S, Chen Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;35(3):1201-18
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;35(3):1201-18
O-Alkylated derivatives of quercetin induce apoptosis of MCF-7 cells via a caspase-independent mitochondrial pathway.
Liao H, Bao X, Zhu J, Qu J, Sun Y, Ma X, Wang E, Guo X, Kang Q, Zhen Y
Chemico-biological interactions 2015 Dec 5;242:91-8
Chemico-biological interactions 2015 Dec 5;242:91-8
Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549.
Chen XM, Bai Y, Zhong YJ, Xie XL, Long HW, Yang YY, Wu SG, Jia Q, Wang XH
PloS one 2013;8(11):e79201
PloS one 2013;8(11):e79201
Induction of apoptosis in infantile hemangioma endothelial cells by propranolol.
Tu JB, Ma RZ, Dong Q, Jiang F, Hu XY, Li QY, Pattar P, Zhang H
Experimental and therapeutic medicine 2013 Aug;6(2):574-578
Experimental and therapeutic medicine 2013 Aug;6(2):574-578
Proteomic analysis of mitochondria from infantile hemangioma endothelial cells treated with sodium morrhuate and its liposomal formulation.
Tu JB, Dong Q, Hu XY, Jiang F, Ma RZ, He LY, Yang ZQ
Journal of biochemical and molecular toxicology 2012 Sep;26(9):374-80
Journal of biochemical and molecular toxicology 2012 Sep;26(9):374-80
Characterization of 9-nitrocamptothecin liposomes: anticancer properties and mechanisms on hepatocellular carcinoma in vitro and in vivo.
Zheng S, Chang S, Lu J, Chen Z, Xie L, Nie Y, He B, Zou S, Gu Z
PloS one 2011;6(6):e21064
PloS one 2011;6(6):e21064
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 17984-1-AP(AIF antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AIF antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AIF. This antibody recognizes human,mouse,rat antigen. The AIF antibody has been validated for the following applications: ELISA, IHC, WB, IP, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-AIF (IP:17984-1-AP, 3ug; Detection:17984-1-AP 1:2000) with HeLa cells lysate 1320ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 17984-1-AP(AIF antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 17984-1-AP(AIF antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
