ABIN197149

antibody from antibodies-online

Targeting: ATF2 CRE-BP1, CREB2, HB16, TREB7

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN197149

Provider

antibodies-online

Product name

anti-Activating Transcription Factor 2 (ATF2) (Thr53), (Thr71) antibody

Antibody type

Polyclonal

Description

Affinity chromatography

Reactivity

Human, Mouse

Host

Rabbit

Epitope

Thr53, Thr71

Vial size

50 μL

Storage

-20°C

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK.

Sevilla A, Santos CR, Vega FM, Lazo PA
The Journal of biological chemistry 2004 Jun 25;279(26):27458-65

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p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease.

Waetzig GH, Seegert D, Rosenstiel P, Nikolaus S, Schreiber S
Journal of immunology (Baltimore, Md. : 1950) 2002 May 15;168(10):5342-51

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Transcription factor ATF2 regulation by the JNK signal transduction pathway.

Gupta S, Campbell D, Dérijard B, Davis RJ
Science (New York, N.Y.) 1995 Jan 20;267(5196):389-93

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ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents.

van Dam H, Wilhelm D, Herr I, Steffen A, Herrlich P, Angel P
The EMBO journal 1995 Apr 18;14(8):1798-811

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Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases.

Abdel-Hafiz HA, Heasley LE, Kyriakis JM, Avruch J, Kroll DJ, Johnson GL, Hoeffler JP
Molecular endocrinology (Baltimore, Md.) 1992 Dec;6(12):2079-89