Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-L1225 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Rabbit Anti-Human CCR3 monoclonal antibody, clone 34I28M2
- Antibody type
- Monoclonal
- Description
- Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR3 (eotaxin receptor), is expressed on eosinophils and certain T cell population respond to a variety of CC chemokines apart from eotaxin, including RANTES, monocyte chemotactic protein (MCP)-2, MCP-3, and MCP-4. CCR3 facilitated infection by a more restricted subset of primary viruses, and binding of the CCR3 ligand, eotaxin, and inhibited infection by these isolates.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 34I28M2
- Concentration
- 0.5 mg/ml
- Storage
- -20°C, Avoid Freeze/Thaw Cycles
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