20932-1-AP

antibody from Proteintech Group

Targeting: TBR1

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

20932-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#20932-1-AP, RRID:AB_10695502

Product name

TBR1 antibody

Antibody type

Polyclonal

Description

TBR1 antibody (Cat. #20932-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding.

Hacisuleyman E, Hale CR, Noble N, Luo JD, Fak JJ, Saito M, Chen J, Weissman JS, Darnell RB
Nature neuroscience 2024 May;27(5):822-835

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Reproducible Differentiation of Human Pluripotent Stem Cells into Two-Dimensional Cortical Neuron Cultures with Checkpoints for Success.

Waxman EA, Dungan LV, DeFlitch LM, Merchant JP, Gagne AL, Goldberg EM, French DL
Current protocols 2023 Dec;3(12):e948

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TRIM67 Implicates in Regulating the Homeostasis and Synaptic Development of Mitral Cells in the Olfactory Bulb.

Cai C, Luo Q, Jia L, Xia Y, Lan X, Wei X, Shi S, Liu Y, Wang Y, Xiong Z, Shi R, Huang C, Chen Z
International journal of molecular sciences 2023 Aug 30;24(17)

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Monitoring Axonal Degeneration in Human Pluripotent Stem Cell Models of Hereditary Spastic Paraplegias.

Li XJ, Mou Y, Milton C, Chen Z
Methods in molecular biology (Clifton, N.J.) 2022;2549:69-83

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Epigenetic Control of circHNRNPH1 in Postischemic Myocardial Fibrosis through Targeting of TGF-β Receptor Type I.

Li W, Wang Y, Deng Y, Ni H, Shen G, Liu X, Li J, Wang F
Molecular therapy. Nucleic acids 2021 Sep 3;25:93-104

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Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs.

Brighi C, Salaris F, Soloperto A, Cordella F, Ghirga S, de Turris V, Rosito M, Porceddu PF, D'Antoni C, Reggiani A, Rosa A, Di Angelantonio S
Cell death & disease 2021 May 15;12(5):498

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Human intermediate progenitor diversity during cortical development.

Pebworth MP, Ross J, Andrews M, Bhaduri A, Kriegstein AR
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 29;118(26)

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AIF3 splicing switch triggers neurodegeneration.

Liu S, Zhou M, Ruan Z, Wang Y, Chang C, Sasaki M, Rajaram V, Lemoff A, Nambiar K, Wang JE, Hatanpaa KJ, Luo W, Dawson TM, Dawson VL, Wang Y
Molecular neurodegeneration 2021 Apr 14;16(1):25

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Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes.

Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, Furuse T, Shibuya H, Yasuda Y, Yamamori H, Fujimoto M, Nagayasu K, Yamamoto K, Kitagawa K, Miura H, Gotoda-Nishimura N, Igarashi H, Hayashida M, Baba M, Kondo M, Hasebe S, Ueshima K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Iguchi T, Sato M, Yamaguchi S, Tamura M, Wakana S, Yoshiki A, Watabe AM, Okano H, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T
Nature communications 2020 Feb 26;11(1):859

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Molecular Correlates of Topiramate and GRIK1 rs2832407 Genotype in Pluripotent Stem Cell-Derived Neural Cultures.

Lieberman R, Jensen KP, Clinton K, Levine ES, Kranzler HR, Covault J
Alcoholism, clinical and experimental research 2020 Aug;44(8):1561-1570

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3D Bioprinted Human Cortical Neural Constructs Derived from Induced Pluripotent Stem Cells.

Salaris F, Colosi C, Brighi C, Soloperto A, Turris V, Benedetti MC, Ghirga S, Rosito M, Di Angelantonio S, Rosa A
Journal of clinical medicine 2019 Oct 2;8(10)

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An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons.

Rhee HJ, Shaib AH, Rehbach K, Lee C, Seif P, Thomas C, Gideons E, Guenther A, Krutenko T, Hebisch M, Peitz M, Brose N, Brüstle O, Rhee JS
Cell reports 2019 May 14;27(7):2212-2228.e7

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Ubiquitin-Specific Protease 15 Maintains Transforming Growth Factor-β Pathway Activity by Deubiquitinating Transforming Growth Factor-β Receptor I during Wound Healing.

Zhao Y, Wang Z, Ho C, Zhang G, Li Q
The American journal of pathology 2019 Jul;189(7):1351-1362

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LIMK1 and LIMK2 regulate cortical development through affecting neural progenitor cell proliferation and migration.

Mao R, Deng R, Wei Y, Han L, Meng Y, Xie W, Jia Z
Molecular brain 2019 Jul 18;12(1):67

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A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology.

Fu H, Possenti A, Freer R, Nakano Y, Hernandez Villegas NC, Tang M, Cauhy PVM, Lassus BA, Chen S, Fowler SL, Figueroa HY, Huey ED, Johnson GVW, Vendruscolo M, Duff KE
Nature neuroscience 2019 Jan;22(1):47-56

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Transcription factor programming of human ES cells generates functional neurons expressing both upper and deep layer cortical markers.

Miskinyte G, Grønning Hansen M, Monni E, Lam M, Bengzon J, Lindvall O, Ahlenius H, Kokaia Z
PloS one 2018;13(10):e0204688

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Impaired mitochondrial dynamics underlie axonal defects in hereditary spastic paraplegias.

Denton K, Mou Y, Xu CC, Shah D, Chang J, Blackstone C, Li XJ
Human molecular genetics 2018 Jul 15;27(14):2517-2530

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Examining the effects of alcohol on GABA(A) receptor mRNA expression and function in neural cultures generated from control and alcohol dependent donor induced pluripotent stem cells.

Lieberman R, Kranzler HR, Levine ES, Covault J
Alcohol (Fayetteville, N.Y.) 2018 Feb;66:45-53

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N-Methyl d-Aspartate Receptor Expression Patterns in the Human Fetal Cerebral Cortex.

Bagasrawala I, Memi F, V Radonjic N, Zecevic N
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Oxygen Levels Regulate the Development of Human Cortical Radial Glia Cells.

Ortega JA, Sirois CL, Memi F, Glidden N, Zecevic N
Cerebral cortex (New York, N.Y. : 1991) 2017 Jul 1;27(7):3736-3751

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Examining FKBP5 mRNA expression in human iPSC-derived neural cells.

Lieberman R, Kranzler HR, Levine ES, Covault J
Psychiatry research 2017 Jan;247:172-181

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Disrupted neuronal maturation in Angelman syndrome-derived induced pluripotent stem cells.

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Nature communications 2017 Apr 24;8:15038

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N-Methyl D-Aspartate Receptor Antagonist Kynurenic Acid Affects Human Cortical Development.

Bagasrawala I, Zecevic N, Radonjić NV
Frontiers in neuroscience 2016;10:435

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Wang Q, Hong P, Gao H, Chen Y, Yang Q, Jiang M, Li H
Scientific reports 2016 Jan 11;6:19003

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PAK1 regulates cortical development via promoting neuronal migration and progenitor cell proliferation.

Pan X, Chang X, Leung C, Zhou Z, Cao F, Xie W, Jia Z
Molecular brain 2015 Jun 5;8:36

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The complexity of the calretinin-expressing progenitors in the human cerebral cortex.

Radonjić NV, Ortega JA, Memi F, Dionne K, Jakovcevski I, Zecevic N
Frontiers in neuroanatomy 2014;8:82

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Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A.

Zhu PP, Denton KR, Pierson TM, Li XJ, Blackstone C
Human molecular genetics 2014 Nov 1;23(21):5638-48

---

Loss of spastin function results in disease-specific axonal defects in human pluripotent stem cell-based models of hereditary spastic paraplegia.

Denton KR, Lei L, Grenier J, Rodionov V, Blackstone C, Li XJ
Stem cells (Dayton, Ohio) 2014 Feb;32(2):414-23

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Diversity of cortical interneurons in primates: the role of the dorsal proliferative niche.

Radonjić NV, Ayoub AE, Memi F, Yu X, Maroof A, Jakovcevski I, Anderson SA, Rakic P, Zecevic N
Cell reports 2014 Dec 24;9(6):2139-51

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

mouse brain tissue were subjected to SDS PAGE followed by western blot with 20932-1-AP(TBR1 antibody) at dilution of 1:1500

Sample type

tissue

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using TBR1 antibody 20932-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human brain using 20932-1-AP(TBR1 antibody) at dilution of 1:100 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human brain using 20932-1-AP(TBR1 antibody) at dilution of 1:100 (under 40x lens)

Sample type

tissue