Antibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 16485-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16485-1-AP, RRID:AB_2291330
- Product name
- CDC25C antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CDC25C antibody (Cat. #16485-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition.
Therapeutic Targeting PLK1 by ON-01910.Na Is Effective in Local Treatment of Retinoblastoma.
Characteristics and clinical significance of polyploid giant cancer cells in laryngeal carcinoma.
RA-XII, a bicyclic hexapeptidic glucoside isolated from Rubia yunnanensis Diels, exerts antitumor activity by inhibiting protective autophagy and activating Akt-mTOR pathway in colorectal cancer cells.
E3 ubiquitin ligase TRIM7 negatively regulates NF-kappa B signaling pathway by degrading p65 in lung cancer.
CyclinB1 deubiquitination by USP14 regulates cell cycle progression in breast cancer.
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression.
Cholesterol depletion sensitizes gallbladder cancer to cisplatin by impairing DNA damage response.
BECN1 promotes the migration of NSCLC cells through regulating the ubiquitination of Vimentin.
Cordycepin suppresses cell proliferation and migration by targeting CLEC2 in human gastric cancer cells via Akt signaling pathway.
Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.
3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase.
S5, a Withanolide Isolated from Physalis Pubescens L., Induces G2/M Cell Cycle Arrest via the EGFR/P38 Pathway in Human Melanoma A375 Cells.
PFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT.
A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity.
Downregulation of vimentin expression increased drug resistance in ovarian cancer cells.
TRIM59 Promotes the Proliferation and Migration of Non-Small Cell Lung Cancer Cells by Upregulating Cell Cycle Related Proteins.
Li Y, Sun C, Tan Y, Zhang H, Li Y, Zou H
International journal of biological sciences 2021;17(2):635-650
International journal of biological sciences 2021;17(2):635-650
Therapeutic Targeting PLK1 by ON-01910.Na Is Effective in Local Treatment of Retinoblastoma.
Ma H, Nie C, Chen Y, Li J, Xie Y, Tang Z, Gao Y, Ai S, Mao Y, Sun Q, Lu R
Oncology research 2021 Sep 7;28(7):745-761
Oncology research 2021 Sep 7;28(7):745-761
Characteristics and clinical significance of polyploid giant cancer cells in laryngeal carcinoma.
Liu HT, Xia T, You YW, Zhang QC, Ni HS, Liu YF, Liu YR, Xu YQ, You B, Zhang ZX
Laryngoscope investigative otolaryngology 2021 Oct;6(5):1228-1234
Laryngoscope investigative otolaryngology 2021 Oct;6(5):1228-1234
RA-XII, a bicyclic hexapeptidic glucoside isolated from Rubia yunnanensis Diels, exerts antitumor activity by inhibiting protective autophagy and activating Akt-mTOR pathway in colorectal cancer cells.
Wang J, Wang J, Li L, Feng L, Wang YR, Wang Z, Tan NH
Journal of ethnopharmacology 2021 Feb 10;266:113438
Journal of ethnopharmacology 2021 Feb 10;266:113438
E3 ubiquitin ligase TRIM7 negatively regulates NF-kappa B signaling pathway by degrading p65 in lung cancer.
Jin J, Lu Z, Wang X, Liu Y, Han T, Wang Y, Wang T, Gan M, Xie C, Wang J, Yu B
Cellular signalling 2020 May;69:109543
Cellular signalling 2020 May;69:109543
CyclinB1 deubiquitination by USP14 regulates cell cycle progression in breast cancer.
Liu B, Liu Y, Wang Y, Xie C, Gan M, Han T, Cao J, Wang J
Pathology, research and practice 2019 Oct;215(10):152592
Pathology, research and practice 2019 Oct;215(10):152592
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
Wang Y, Han T, Gan M, Guo M, Xie C, Jin J, Zhang S, Wang P, Cao J, Wang JB
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032
RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression.
Guo D, Wang Y, Wang J, Song L, Wang Z, Mao B, Tan N
Molecules (Basel, Switzerland) 2019 May 12;24(9)
Molecules (Basel, Switzerland) 2019 May 12;24(9)
Cholesterol depletion sensitizes gallbladder cancer to cisplatin by impairing DNA damage response.
Zhang Y, Liu Y, Duan J, Wang H, Zhang Y, Qiao K, Wang J
Cell cycle (Georgetown, Tex.) 2019 Dec;18(23):3337-3350
Cell cycle (Georgetown, Tex.) 2019 Dec;18(23):3337-3350
BECN1 promotes the migration of NSCLC cells through regulating the ubiquitination of Vimentin.
Cheng Z, Xin H, Han T
Cell adhesion & migration 2019 Dec;13(1):249-259
Cell adhesion & migration 2019 Dec;13(1):249-259
Cordycepin suppresses cell proliferation and migration by targeting CLEC2 in human gastric cancer cells via Akt signaling pathway.
Wang Y, Lv Y, Liu TS, Yan WD, Chen LY, Li ZH, Piao YS, An RB, Lin ZH, Ren XS
Life sciences 2019 Apr 15;223:110-119
Life sciences 2019 Apr 15;223:110-119
Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.
Liu S, Liu B
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 9;24:1424-1433
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 9;24:1424-1433
3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase.
Li W, Liu J, Fu W, Zheng X, Ren L, Liu S, Wang J, Ji T, Du G
Journal of experimental & clinical cancer research : CR 2018 Jul 3;37(1):132
Journal of experimental & clinical cancer research : CR 2018 Jul 3;37(1):132
S5, a Withanolide Isolated from Physalis Pubescens L., Induces G2/M Cell Cycle Arrest via the EGFR/P38 Pathway in Human Melanoma A375 Cells.
Fan Y, Mao Y, Cao S, Xia G, Zhang Q, Zhang H, Qiu F, Kang N
Molecules (Basel, Switzerland) 2018 Dec 1;23(12)
Molecules (Basel, Switzerland) 2018 Dec 1;23(12)
PFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT.
Shi WK, Zhu XD, Wang CH, Zhang YY, Cai H, Li XL, Cao MQ, Zhang SZ, Li KS, Sun HC
Cell death & disease 2018 Apr 1;9(4):428
Cell death & disease 2018 Apr 1;9(4):428
A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity.
Xu X, Fan Z, Liang C, Li L, Wang L, Liang Y, Wu J, Chang S, Yan Z, Lv Z, Fu J, Liu Y, Jin S, Wang T, Hong T, Dong Y, Ding L, Cheng L, Liu R, Fu S, Jiao S, Ye Q
Nature communications 2017 Jan 17;8:14059
Nature communications 2017 Jan 17;8:14059
Downregulation of vimentin expression increased drug resistance in ovarian cancer cells.
Huo Y, Zheng Z, Chen Y, Wang Q, Zhang Z, Deng H
Oncotarget 2016 Jul 19;7(29):45876-45888
Oncotarget 2016 Jul 19;7(29):45876-45888
TRIM59 Promotes the Proliferation and Migration of Non-Small Cell Lung Cancer Cells by Upregulating Cell Cycle Related Proteins.
Zhan W, Han T, Zhang C, Xie C, Gan M, Deng K, Fu M, Wang JB
PloS one 2015;10(11):e0142596
PloS one 2015;10(11):e0142596
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CDC25C antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CDC25C. This antibody recognizes human antigen. The CDC25C antibody has been validated for the following applications: ELISA, WB analysis.