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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations [0]
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- Product number
- ABIN362093 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN362093, RRID:AB_10952314
- Product name
- anti-Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C) (pSer216) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pSer216 (S-P-S (p) -M-P) derived from Human cdc25C. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer216
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases.
Regulating mammalian checkpoints through Cdc25 inactivation.
Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathway.
Plk1 promotes nuclear translocation of human Cdc25C during prophase.
Ferguson AM, White LS, Donovan PJ, Piwnica-Worms H
Molecular and cellular biology 2005 Apr;25(7):2853-60
Molecular and cellular biology 2005 Apr;25(7):2853-60
Regulating mammalian checkpoints through Cdc25 inactivation.
Donzelli M, Draetta GF
EMBO reports 2003 Jul;4(7):671-7
EMBO reports 2003 Jul;4(7):671-7
Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathway.
Chen F, Zhang Z, Bower J, Lu Y, Leonard SS, Ding M, Castranova V, Piwnica-Worms H, Shi X
Proceedings of the National Academy of Sciences of the United States of America 2002 Feb 19;99(4):1990-5
Proceedings of the National Academy of Sciences of the United States of America 2002 Feb 19;99(4):1990-5
Plk1 promotes nuclear translocation of human Cdc25C during prophase.
Toyoshima-Morimoto F, Taniguchi E, Nishida E
EMBO reports 2002 Apr;3(4):341-8
EMBO reports 2002 Apr;3(4):341-8
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