10024-2-AP

antibody from Proteintech Group

Targeting: JUN AP-1, c-Jun

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Antibody Data

Product number

10024-2-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#10024-2-AP, RRID:AB_2129714

Product name

AP1,JUN,P39 antibody

Antibody type

Polyclonal

Description

KD/KO validated AP1,JUN,P39 antibody (Cat. #10024-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

IMM-H007, a novel small molecule inhibitor for atherosclerosis, represses endothelium inflammation by regulating the activity of NF-κB and JNK/AP1 signaling.

Yu J, Ming H, Li HY, Yu B, Chu M, Zhu H, Zhu X
Toxicology and applied pharmacology 2019 Oct 15;381:114732

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Adipose-derived mesenchymal stem cells ameliorate the inflammatory reaction in CLP-induced septic acute lung injury rats via sTNFR1.

Ding XF, Liang HY, Sun JY, Liu SH, Kan QC, Wang LX, Sun TW
Journal of cellular physiology 2019 Feb 18;

---

Correction: Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.

Dong D, Qi Y, Xu L, Yin L, Xu Y, Han X, Zhao Y, Peng J
Food & function 2019 Aug 1;10(8):5240-5241

---

Maternal Protein Restriction Induces Alterations in Hepatic Unfolded Protein Response-Related Molecules in Adult Rat Offspring.

Liu X, Wang J, Gao L, Jiao Y, Liu C
Frontiers in endocrinology 2018;9:676

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Selenoprotein S Attenuates Tumor Necrosis Factor-α-Induced Dysfunction in Endothelial Cells.

Cui S, Men L, Li Y, Zhong Y, Yu S, Li F, Du J
Mediators of inflammation 2018;2018:1625414

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USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein.

Chen S, Yun F, Yao Y, Cao M, Zhang Y, Wang J, Song X, Qian Y
The Journal of experimental medicine 2018 Nov 5;215(11):2850-2867

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Matrix stiffness-upregulated LOXL2 promotes fibronectin production, MMP9 and CXCL12 expression and BMDCs recruitment to assist pre-metastatic niche formation.

Wu S, Zheng Q, Xing X, Dong Y, Wang Y, You Y, Chen R, Hu C, Chen J, Gao D, Zhao Y, Wang Z, Xue T, Ren Z, Cui J
Journal of experimental & clinical cancer research : CR 2018 May 4;37(1):99

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Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.

Qiao Y, Xu L, Tao X, Yin L, Qi Y, Xu Y, Han X, Tang Z, Ma X, Liu K, Peng J
Toxicology letters 2018 Mar 1;284:37-45

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A CREB1/miR-433 reciprocal feedback loop modulates proliferation and metastasis in colorectal cancer.

Yan L, You WQ, Sheng NQ, Gong JF, Hu LD, Tan GW, Chen HQ, Wang ZG
Aging 2018 Dec 6;10(12):3774-3793

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Oncogenic Activation of Nrf2, Though as a Master Antioxidant Transcription Factor, Liberated by Specific Knockout of the Full-Length Nrf1α that Acts as a Dominant Tumor Repressor.

Qiu L, Wang M, Hu S, Ru X, Ren Y, Zhang Z, Yu S, Zhang Y
Cancers 2018 Dec 17;10(12)

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α-Iso-Cubebene Inhibits PDGF-Induced Vascular Smooth Muscle Cell Proliferation by Suppressing Osteopontin Expression.

Jang MA, Lee SJ, Baek SE, Park SY, Choi YW, Kim CD
PloS one 2017;12(1):e0170699

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Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.

Liu Z, Wang Y, Wang Y, Dong W, Xia X, Song E, Song Y
Chemical research in toxicology 2017 Oct 16;30(10):1804-1814

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Divergent JNK Phosphorylation of HDAC3 in Triple-Negative Breast Cancer Cells Determines HDAC Inhibitor Binding and Selectivity.

Hanigan TW, Aboukhatwa SM, Taha TY, Frasor J, Petukhov PA
Cell chemical biology 2017 Nov 16;24(11):1356-1367.e8

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PKCζ phosphorylates TRAF2 to protect against intestinal ischemia-reperfusion-induced injury.

Zhou W, Yao J, Wang G, Chen Z, Li Z, Feng D, Li Y, Qasim W, Tan W, Ning S, Tian X
Cell death & disease 2017 Jul 20;8(7):e2935

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Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation.

Yao S, Xu F, Chen Y, Ge Y, Zhang F, Huang H, Li L, Lin D, Luo X, Xu J, Luo D, Zhu X, Liu Y
Journal of experimental & clinical cancer research : CR 2017 Jan 10;36(1):10

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TGF-β Down-regulates Apolipoprotein M Expression through the TAK-1-JNK-c-Jun Pathway in HepG2 Cells.

Ren K, Mo ZC, Liu X, Tang ZL, Jiang Y, Peng XS, Zhang QH, Shi JF, Yi GH
Lipids 2017 Feb;52(2):109-117

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Sepsis reveals compartment-specific responses in intestinal proliferation and apoptosis in transgenic mice whose enterocytes re-enter the cell cycle.

Lyons JD, Klingensmith NJ, Otani S, Mittal R, Liang Z, Ford ML, Coopersmith CM
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Dec;31(12):5507-5519

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Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.

Wang H, Xu YS, Wang ML, Cheng C, Bian R, Yuan H, Wang Y, Guo T, Zhu LL, Zhou H
International journal of molecular medicine 2017 Apr;39(4):819-830

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The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.

Fu J, Xia X, Liu Z, Wang Y, Wang Y, Shi Q, Song X, Song E, Song Y
Toxicology 2017 Apr 15;381:39-50

---

Dioscin attenuates gastric ischemia/reperfusion injury through the down-regulation of PKC/ERK1/2 signaling via PKCα and PKCβ2 inhibition.

Hu Y, Tao X, Han X, Xu L, Yin L, Qi Y, Zhao Y, Xu Y, Wang C, Peng J
Chemico-biological interactions 2016 Oct 25;258:234-44

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Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.

Tao X, Sun X, Xu L, Yin L, Han X, Qi Y, Xu Y, Zhao Y, Wang C, Peng J
Nutrients 2016 Jul 8;8(7)

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Induction of COX-2-PGE2 synthesis by activation of the MAPK/ERK pathway contributes to neuronal death triggered by TDP-43-depleted microglia.

Xia Q, Hu Q, Wang H, Yang H, Gao F, Ren H, Chen D, Fu C, Zheng L, Zhen X, Ying Z, Wang G
Cell death & disease 2015 Mar 26;6:e1702

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Potent effects of dioscin against obesity in mice.

Liu M, Xu L, Yin L, Qi Y, Xu Y, Han X, Zhao Y, Sun H, Yao J, Lin Y, Liu K, Peng J
Scientific reports 2015 Jan 22;5:7973

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Potent effects of dioscin against liver fibrosis.

Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, Sun H, Lin Y, Liu K, Peng J
Scientific reports 2015 Apr 8;5:9713

---

Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis.

Tao X, Wan X, Xu Y, Xu L, Qi Y, Yin L, Han X, Lin Y, Peng J
Transplantation 2014 Sep 27;98(6):604-11

---

Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.

Dong D, Qi Y, Xu L, Yin L, Xu Y, Han X, Zhao Y, Peng J
Food & function 2014 Dec;5(12):3065-3075

---

Potent effects of flavonoid-rich extract from Rosa laevigata Michx fruit against hydrogen peroxide-induced damage in PC12 cells via attenuation of oxidative stress, inflammation and apoptosis.

Liu M, Xu Y, Han X, Liang C, Yin L, Xu L, Qi Y, Zhao Y, Peng J, Sun C
Molecules (Basel, Switzerland) 2014 Aug 7;19(8):11816-32

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The AP1,JUN,P39 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AP1,JUN,P39. This antibody recognizes human, mouse, rat antigen. The AP1,JUN,P39 antibody has been validated for the following applications: ELISA, WB analysis.

Appendix

10024-2-AP.pdf

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