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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Product number
- ABIN361919 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN361919, RRID:AB_10954017
- Product name
- anti-Jun Proto-Oncogene (JUN) (pThr239) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pThr239 (G-E-T (p) -P-P) derived from Human c-Jun. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed bychromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pThr239
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Oncogenic functions of secreted Frizzled-related protein 2 in human renal cancer.
The stress-activated protein kinase subfamily of c-Jun kinases.
JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain.
Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain.
Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity.
Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73.
Yamamura S, Kawakami K, Hirata H, Ueno K, Saini S, Majid S, Dahiya R
Molecular cancer therapeutics 2010 Jun;9(6):1680-7
Molecular cancer therapeutics 2010 Jun;9(6):1680-7
The stress-activated protein kinase subfamily of c-Jun kinases.
Kyriakis JM, Banerjee P, Nikolakaki E, Dai T, Rubie EA, Ahmad MF, Avruch J, Woodgett JR
Nature 1994 May 12;369(6476):156-60
Nature 1994 May 12;369(6476):156-60
JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain.
Dérijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, Karin M, Davis RJ
Cell 1994 Mar 25;76(6):1025-37
Cell 1994 Mar 25;76(6):1025-37
Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain.
Binétruy B, Smeal T, Karin M
Nature 1991 May 9;351(6322):122-7
Nature 1991 May 9;351(6322):122-7
Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity.
Boyle WJ, Smeal T, Defize LH, Angel P, Woodgett JR, Karin M, Hunter T
Cell 1991 Feb 8;64(3):573-84
Cell 1991 Feb 8;64(3):573-84
Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73.
Smeal T, Binetruy B, Mercola DA, Birrer M, Karin M
Nature 1991 Dec 12;354(6353):494-6
Nature 1991 Dec 12;354(6353):494-6
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