ABIN196613

antibody from antibodies-online

Targeting: JUN AP-1, c-Jun

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN196613

Provider

antibodies-online

Product name

anti-Jun Proto-Oncogene (JUN) (pSer73) antibody

Antibody type

Polyclonal

Description

Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pSer73

Vial size

50 μL

Storage

Store the antibody (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK).

Sevilla A, Santos CR, Barcia R, Vega FM, Lazo PA
Oncogene 2004 Nov 25;23(55):8950-8

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Large-scale characterization of HeLa cell nuclear phosphoproteins.

Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP
Proceedings of the National Academy of Sciences of the United States of America 2004 Aug 17;101(33):12130-5

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain.

Dérijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, Karin M, Davis RJ
Cell 1994 Mar 25;76(6):1025-37

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Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain.

Binétruy B, Smeal T, Karin M
Nature 1991 May 9;351(6322):122-7

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Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73.

Smeal T, Binetruy B, Mercola DA, Birrer M, Karin M
Nature 1991 Dec 12;354(6353):494-6