ABIN965723

antibody from antibodies-online

Targeting: JUN AP-1, c-Jun

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN965723

Provider

antibodies-online

Product name

anti-Jun Proto-Oncogene (JUN) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized non-phosphopeptide derived from human c-Jun around the phosphorylation site of serine 243 (P-L-SP-PI).

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

100 μg

Concentration

100ug/100ul

Storage

-20°C

References

Submitted references

The stress-activated protein kinase subfamily of c-Jun kinases.

Kyriakis JM, Banerjee P, Nikolakaki E, Dai T, Rubie EA, Ahmad MF, Avruch J, Woodgett JR
Nature 1994 May 12;369(6476):156-60

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain.

Dérijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, Karin M, Davis RJ
Cell 1994 Mar 25;76(6):1025-37

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Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain.

Binétruy B, Smeal T, Karin M
Nature 1991 May 9;351(6322):122-7

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Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity.

Boyle WJ, Smeal T, Defize LH, Angel P, Woodgett JR, Karin M, Hunter T
Cell 1991 Feb 8;64(3):573-84

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Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73.

Smeal T, Binetruy B, Mercola DA, Birrer M, Karin M
Nature 1991 Dec 12;354(6353):494-6