ABIN967578

antibody from antibodies-online

Targeting: JUN AP-1, c-Jun

Western blot (Data presented on provider website)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN967578

Provider

antibodies-online

Product name

anti-Jun Proto-Oncogene (JUN) (pSer63) antibody

Antibody type

Monoclonal

Antigen

Other

Description

Purified from tissue culture supernatant or ascites by affinity chromatography.

Reactivity

Human

Host

Mouse

Epitope

pSer63

Isotype

IgG

Antibody clone number

2

Vial size

0.1 mg

Concentration

0.25 mg/ml

Storage

-20°C

References

Submitted references

Deregulated repression of c-Jun provides a potential link to its role in tumorigenesis.

Weiss C, Bohmann D
Cell cycle (Georgetown, Tex.) 2004 Feb;3(2):111-3

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Molecular mechanism and biological functions of c-Jun N-terminal kinase signalling via the c-Jun transcription factor.

Dunn C, Wiltshire C, MacLaren A, Gillespie DA
Cellular signalling 2002 Jul;14(7):585-93

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AP-1 in cell proliferation and survival.

Shaulian E, Karin M
Oncogene 2001 Apr 30;20(19):2390-400

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Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation.

Behrens A, Sibilia M, Wagner EF
Nature genetics 1999 Mar;21(3):326-9

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c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms.

Wisdom R, Johnson RS, Moore C
The EMBO journal 1999 Jan 4;18(1):188-97

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Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73.

Smeal T, Binetruy B, Mercola D, Grover-Bardwick A, Heidecker G, Rapp UR, Karin M
Molecular and cellular biology 1992 Aug;12(8):3507-13

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Induction of proto-oncogene JUN/AP-1 by serum and TPA.

Lamph WW, Wamsley P, Sassone-Corsi P, Verma IM
Nature 1988 Aug 18;334(6183):629-31