19703-1-AP

antibody from Proteintech Group

Targeting: MT-ND1 MTND1, NAD1, ND1

Provider product page for 19703-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [98]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]

Submit

Product number: 19703-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#19703-1-AP, RRID:AB_10637853
Product name: ND1 antibody
Antibody type: Polyclonal
Description: KD/KO validated ND1 antibody (Cat. #19703-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

MT-ND1 protein structure - 19703-1-AP shown in red.

Submitted references SIRT6-Mediated Regulation of TFAM: A Central Mechanism Connecting Nuclear and Mitochondrial Transcriptional Processes and Mitophagy.

Jiang M, Li J, Ding N, Jia G, Wu S, Liu N, Kang Y, Zhang G, Wu J, Zhang L, Zhang Y
International journal of biological sciences 2026;22(1):178-200

Metformin reduces senescence induced by obesity-related inflammation in luminal breast cancer through estrogen receptor beta modulation.

Morla-Barcelo PM, Melguizo-Salom L, Martinez-Bernabe T, Roca P, Sastre-Serra J, Nadal-Serrano M
Biochemical pharmacology 2026 Jul;249:117930

Targeting TFAM K76 acetylation attenuates mitochondrial dysfunction and kidney injury in diabetic kidney disease.

Fu T, Sun S, Wang Z, Zhao F, Zhen J, Ji X, Xue F, Mu Q, Wang Y, Liu Y, Wan Q
Cardiovascular diabetology 2026 Feb 3;25(1)

Hyperglycemia impairs cognitive function by inducing mitochondrial damage through lactylation of LRPPRC at K223.

Xu J, Hao Y, Cao J, Yang X, Gao Y, Sun X, Nie R, Zhong Q, Zhong Y, Zhong J, Zheng T
EMBO molecular medicine 2026 Apr 6;

Calcium dysregulation disrupts mitochondrial homeostasis by interfering AMPK/Drp1 pathway to aggravate plaque progression and instability.

Hu P, Liu M, Wu T, Zhang Y, Liu C, Wang L, Zhang W, Que Y, You J, Yu W, Tong X
Theranostics 2025;15(15):7567-7583

Mitochonic acid 5 increases boar sperm quality by mitigating mitochondrial dysfunction.

Wang R, Adetunji AO, Min L, Zhu Z
Frontiers in cell and developmental biology 2025;13:1583951

HMGA2/PHGDH axis-mediated glycolysis under hypoxia is required for cadmium-induced A549 cell migration.

Gao C, Xie Q, Li L, Luo S, Fan J, Cao J
Ecotoxicology and environmental safety 2025 Sep 15;303:118787

Mitochondrial ribosomal protein L12 mediates metabolic reorganization in clear cell renal cell carcinoma by regulating mitochondrial biosynthesis.

Sun S, Su D, Dong T, Wang B, Ji X, Chu L, Lu S, Zhang T, Sun X, Liu Y, Wan Q
Cell communication and signaling : CCS 2025 Oct 14;23(1):435

Astragaloside IV potentiates cisplatin sensitivity in triple-negative breast cancer via STING signaling pathway activation.

Bai B, Zhang L, Zhang Y, Yue R, Lu Y, Shi R, Zhou Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157330

Asparagine deprivation enhances T cell antitumour response in patients via ROS-mediated metabolic and signal adaptations.

Chang HC, Tsai CY, Hsu CL, Tai TS, Cheng ML, Chuang YM, Tang HY, Lin KJ, Chen JJ, Chang SH, Ko YC, Chi YW, Liu H, Tan BC, Shen CR, Yang CW, Ho PC, Yang HY
Nature metabolism 2025 May;7(5):918-927

Dental pulp stem cells alleviate Schwann cell pyroptosis via mitochondrial transfer to enhance facial nerve regeneration.

Zheng X, Wang J, Zhou H, Chai Y, Li Z, Chen M, Yang Z, Xu C, Lei C, He Y, Zou D, Ye Q
Bioactive materials 2025 May;47:313-326

Design, Synthesis and Biological Evaluation of POLRMT Inhibitors for the Treatment of Acute Myeloid Leukemia.

Liu T, Cheng X, Wang Y, Hao W, Wang H, Zhang K, Wang J
Chemical biology & drug design 2025 May;105(5):e70127

Modulation of mitochondrial functions contributes to the protection of lamotrigine against Alzheimer's disease.

Fu XX, Wei B, Huang ZH, Duan R, Deng Y, E Y, Wang SY, Chen SY, Zhang YD, Jiang T
Journal of Alzheimer's disease : JAD 2025 Mar;104(1):209-220

Characterization of a new mutation of mitochondrial ND6 gene in hepatocellular carcinoma and its effects on respiratory complex I.

Bazzani V, Kundnani DL, Redin ME, Agostini F, Chhatlani K, Faini AC, Poziemski J, Baccarani U, Siedlecki P, Deaglio S, Storici F, Vascotto C
Scientific reports 2025 Mar 29;15(1):10925

Peptide YY fragment PYY1-36 disrupts mitochondrial biogenesis via RBM43-dependent PGC-1α translation inhibition.

Liu B, Zhou F, Shi B, Yan Y, Wang Y, Wang J, Lang Y, Xu S
Investigational new drugs 2025 Jun;43(3):669-678

Olesoxime protects against cisplatin-induced acute kidney injury by attenuating mitochondrial dysfunction.

Wang P, Ouyang J, Zhou K, Hu D, Zhang S, Zhang A, Yang Y
Biomedical journal 2025 Feb;48(1):100730

CRIP1 inhibits cutaneous melanoma progression through TFAM-mediated mitochondrial biogenesis.

Wu J, Chen L, Wen P
Scientific reports 2025 Feb 4;15(1):4298

Leber's hereditary optic neuropathy-associated ND1 3733G>C mutation ameliorates the mitochondrial quality control and cellular homeostasis.

Yasheng M, Ji Y, He Y, Yi Q, Zhang H, Shan W, Wang K, Zhang J, Li Y, Meng F, Zhang M, Mo JQ, Wei S, Guan MX
The Journal of biological chemistry 2025 Aug;301(8):110464

MRPL12 K163 acetylation inhibits ccRCC via driving mitochondrial metabolic reprogramming.

Ji X, Xue F, Wang Y, Gao D, Sun J, Dong T, Mu Q, Xu Q, Sun S, Liu Y, Wan Q
Cell death & disease 2025 Aug 26;16(1):646

Temporal expression of mitochondrial life cycle markers during acute and chronic overload of rat plantaris muscles.

Hyatt JK, Lu EJ, McCall GE
Frontiers in physiology 2024;15:1420276

UBASH3B-mediated MRPL12 Y60 dephosphorylation inhibits LUAD development by driving mitochondrial metabolism reprogramming.

Ji X, Zhang T, Sun J, Song X, Ma G, Xu L, Cao X, Jing Y, Xue F, Zhang W, Sun S, Wan Q, Liu Y
Journal of experimental & clinical cancer research : CR 2024 Sep 30;43(1):268

Sorafenib induces cachexia by impeding transcriptional signaling of the SET1/MLL complex on muscle-specific genes.

Khan B, Lanzuolo C, Rosti V, Santarelli P, Pich A, Kraft T, Amrute-Nayak M, Nayak A
iScience 2024 Oct 18;27(10):110913

Aging-induced tRNA(Glu)-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization.

Li D, Gao X, Ma X, Wang M, Cheng C, Xue T, Gao F, Shen Y, Zhang J, Liu Q
Cell metabolism 2024 May 7;36(5):1059-1075.e9

Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway.

Miao ZF, Sun JX, Huang XZ, Bai S, Pang MJ, Li JY, Chen HY, Tong QY, Ye SY, Wang XY, Hu XH, Li JY, Zou JW, Xu W, Yang JH, Lu X, Mills JC, Wang ZN
Developmental cell 2024 May 6;59(9):1175-1191.e7

Effects of Dityrosine on Lactic Acid Metabolism in Mice Gastrocnemius Muscle During Endurance Exercise via the Oxidative Stress-Induced Mitochondria Damage.

Xia Q, Lan J, Pan Y, Wang Y, Song T, Yang Y, Tian X, Chen L, Gu Z, Ding YY
Journal of agricultural and food chemistry 2024 Mar 13;72(10):5269-5282

AIM2 regulates autophagy to mitigate oxidative stress in aged mice with acute liver injury.

Hu C, Li M, Chen Y, Cheng W, Wang H, Zhou Y, Teng F, Ling T, Pan J, Xu H, Zheng Y, Ji G, Zhao T, You Q
Cell death discovery 2024 Mar 1;10(1):107

Nmnat1 Deficiency Causes Mitoribosome Excess in Diabetic Nephropathy Mediated by Transcriptional Repressor HIC1.

Hasegawa K, Tamaki M, Sakamaki Y, Wakino S
International journal of molecular sciences 2024 Jun 9;25(12)

Mitochonic Acid 5 Increases Ram Sperm Quality by Improving Mitochondrial Function during Storage at 4 °C.

Wang R, Liu L, Min L, Adetunji AO, Kou X, Zhou K, Zhu Z
Animals : an open access journal from MDPI 2024 Jan 23;14(3)

SERCA2 dysfunction triggers hypertension by interrupting mitochondrial homeostasis and provoking oxidative stress.

Wang Y, Wang M, Su H, Song J, Ren M, Hu P, Liu G, Tong X
Free radical biology & medicine 2024 Feb 20;212:284-294

MT-TN mutations lead to progressive mitochondrial encephalopathy and promotes mitophagy.

Duan H, Pan C, Wu T, Peng J, Yang L
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167043

TAX1BP1 contributes to deoxypodophyllotoxin-induced glioma cell parthanatos via inducing nuclear translocation of AIF by activation of mitochondrial respiratory chain complex I.

Wang XZ, Liang SP, Chen X, Wang ZC, Li C, Feng CS, Lu S, He C, Wang YB, Chi GF, Ge PF
Acta pharmacologica Sinica 2023 Sep;44(9):1906-1919

FAM210A is essential for cold-induced mitochondrial remodeling in brown adipocytes.

Qiu J, Yue F, Zhu P, Chen J, Xu F, Zhang L, Kim KH, Snyder MM, Luo N, Xu HW, Huang F, Tao WA, Kuang S
Nature communications 2023 Oct 10;14(1):6344

MUC1-C integrates aerobic glycolysis with suppression of oxidative phosphorylation in triple-negative breast cancer stem cells.

Yamashita N, Withers H, Morimoto Y, Bhattacharya A, Haratake N, Daimon T, Fushimi A, Nakashoji A, Thorner AR, Isenhart E, Rosario S, Long MD, Kufe D
iScience 2023 Nov 17;26(11):108168

FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.

Wu J, Subbaiah KCV, Hedaya O, Chen S, Munger J, Tang WHW, Yan C, Yao P
bioRxiv : the preprint server for biology 2023 May 22;

MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells.

Ji X, Chu L, Su D, Sun J, Song P, Sun S, Wang Y, Mu Q, Liu Y, Wan Q
iScience 2023 May 19;26(5):106656

Myocardial ischemia-reperfusion injury is probably due to the excessive production of mitochondrial ROS caused by the activation of 5-HT degradation system mediated by PAF receptor.

Jin J, Xu F, Zhang Y, Guan J, Fu J
Molecular immunology 2023 Mar;155:27-43

Expanding DdCBE-mediated targeting scope to aC motif preference in rat.

Qi X, Tan L, Zhang X, Jin J, Kong W, Chen W, Wang J, Dong W, Gao L, Luo L, Lu D, Gong J, Guan F, Shu W, Huang X, Zhang L, Wang S, Shen B, Ma Y
Molecular therapy. Nucleic acids 2023 Jun 13;32:1-12

The mitophagy receptor NIX induces vIRF-1 oligomerization and interaction with GABARAPL1 for the promotion of HHV-8 reactivation-induced mitophagy.

Vo MT, Choi CY, Choi YB
PLoS pathogens 2023 Jul;19(7):e1011548

Dynamic mapping of proteome trafficking within and between living cells by TransitID.

Qin W, Cheah JS, Xu C, Messing J, Freibaum BD, Boeynaems S, Taylor JP, Udeshi ND, Carr SA, Ting AY
Cell 2023 Jul 20;186(15):3307-3324.e30

ER stress-enhanced HMGA2 plays an important role in Cr (VI)-induced glycolysis and inhibited oxidative phosphorylation by targeting the transcription of ATF4.

Luo S, Zhang C, Gao Z, Jiang L, Li Q, Shi X, Kong Y, Cao J
Chemico-biological interactions 2023 Jan 5;369:110293

Dynamic mapping of proteome trafficking within and between living cells by TransitID.

Xu WQ, Cheah JS, Xu C, Messing J, Freibaum BD, Boeynaems S, Taylor JP, Udeshi ND, Carr SA, Ting AY
bioRxiv : the preprint server for biology 2023 Feb 8;

Inhibitor of nuclear factor kappa B kinase subunit epsilon regulates murine acetaminophen toxicity via RIPK1/JNK.

Xu Y, Xu H, Ling T, Cui Y, Zhang J, Mu X, Zhou D, Zhao T, Li Y, Su Z, You Q
Cell biology and toxicology 2023 Dec;39(6):2709-2724

Optimized allotopic expression of mitochondrial ND6 transgene restored complex I and apoptosis deficiencies caused by LHON-linked ND6 14484T > C mutation.

Wang J, Ji Y, Ai C, Chen JR, Gan D, Zhang J, Mo JQ, Guan MX
Journal of biomedical science 2023 Aug 3;30(1):63

MTH1 protects platelet mitochondria from oxidative damage and regulates platelet function and thrombosis.

Ding Y, Gui X, Chu X, Sun Y, Zhang S, Tong H, Ju W, Li Y, Sun Z, Xu M, Li Z, Andrews RK, Gardiner EE, Zeng L, Xu K, Qiao J
Nature communications 2023 Aug 10;14(1):4829

A conditional knockout rat resource of mitochondrial protein-coding genes via a DdCBE-induced premature stop codon.

Tan L, Qi X, Kong W, Jin J, Lu D, Zhang X, Wang Y, Wang S, Dong W, Shi X, Chen W, Wang J, Li K, Xie Y, Gao L, Guan F, Gao K, Li C, Wang C, Hu Z, Zhang L, Guo X, Shen B, Ma Y
Science advances 2023 Apr 14;9(15):eadf2695

Reduced Immunity Regulator MAVS Contributes to Non-Hypertrophic Cardiac Dysfunction by Disturbing Energy Metabolism and Mitochondrial Homeostasis.

Wang Q, Sun Z, Cao S, Lin X, Wu M, Li Y, Yin J, Zhou W, Huang S, Zhang A, Zhang Y, Xia W, Jia Z
Frontiers in immunology 2022;13:919038

Leber's hereditary optic neuropathy-associated ND6 14484T > C mutation caused pleiotropic effects on the complex I, RNA homeostasis, apoptosis and mitophagy.

Liang M, Ji Y, Zhang L, Wang X, Hu C, Zhang J, Zhu Y, Mo JQ, Guan MX
Human molecular genetics 2022 Sep 29;31(19):3299-3312

P53 regulates mitochondrial biogenesis via transcriptionally induction of mitochondrial ribosomal protein L12.

Han Y, Liu Y, Zhen J, Hou S, Zhang B, Cui Z, Wan Q, Feng H
Experimental cell research 2022 Sep 1;418(1):113249

Inhibition of High-Temperature Requirement Protein A2 Protease Activity Represses Myogenic Differentiation via UPRmt.

Sun H, Shen L, Zhang P, Lin F, Ma J, Wu Y, Yu H, Sun L
International journal of molecular sciences 2022 Oct 4;23(19)

HMGA2 mediates Cr (VI)-induced metabolic reprogramming through binding to mitochondrial D-Loop region.

Bao S, Zhang C, Luo S, Jiang L, Li Q, Kong Y, Cao J
Ecotoxicology and environmental safety 2022 Oct 1;244:114085

Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.

Jiang B, Zhang J, Zhao G, Liu M, Hu J, Lin F, Wang J, Zhao W, Ma H, Zhang C, Wu C, Yao L, Liu Q, Chen X, Cao Y, Zheng Y, Zhang C, Han A, Lin D, Li Q
Molecular cell 2022 May 19;82(10):1821-1835.e6

Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.

Shen R, Yang K, Cheng X, Guo C, Xing X, Sun H, Liu D, Liu X, Wang D
Environmental pollution (Barking, Essex : 1987) 2022 May 1;300:118986

Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I.

Jain S, Hu C, Kluza J, Ke W, Tian G, Giurgiu M, Bleilevens A, Campos AR, Charbono A, Stickeler E, Maurer J, Holinski-Feder E, Vaisburg A, Bureik M, Luo G, Marchetti P, Cheng Y, Wolf DA
Cell chemical biology 2022 Mar 17;29(3):436-450.e15

Carbon tetrachloride induced mitochondrial division, respiratory chain damage, abnormal intracellular [H(+)] and apoptosis are due to the activation of 5-HT degradation system in hepatocytes.

Zhang Y, Liang X, Guan J, Jin J, Zhang Y, Xu F, Fu J
Toxicology and applied pharmacology 2022 Mar 15;439:115929

LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.

Zhao K, Huang X, Zhao W, Lu B, Yang Z
Development (Cambridge, England) 2022 Mar 15;149(6)

Increased fatty acid metabolism attenuates cardiac resistance to β-adrenoceptor activation via mitochondrial reactive oxygen species: A potential mechanism of hypoglycemia-induced myocardial injury in diabetes.

Huang L, Chen Z, Chen R, Lin L, Ren L, Zhang M, Liu L
Redox biology 2022 Jun;52:102320

Mitochondrial Ribosome Dysfunction in Human Alveolar Type II Cells in Emphysema.

Karim L, Lin CR, Kosmider B, Criner G, Marchetti N, Bolla S, Bowler R, Bahmed K
Biomedicines 2022 Jun 24;10(7)

Serine protease HtrA2/Omi regulates adaptive mitochondrial reprogramming in the brain cortex after ischemia/reperfusion injury via UCP2-SIRT3-PGC1 axis.

Meng H, Sun LK, Su J, Yan WY, Jin Y, Luo X, Jiang XR, Wang HL
Human cell 2022 Jan;35(1):63-82

Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.

Xu Z, Fu T, Guo Q, Zhou D, Sun W, Zhou Z, Chen X, Zhang J, Liu L, Xiao L, Yin Y, Jia Y, Pang E, Chen Y, Pan X, Fang L, Zhu MS, Fei W, Lu B, Gan Z
Nature communications 2022 Feb 16;13(1):894

ING2 Controls Mitochondrial Respiration via Modulating MRPL12 Ubiquitination in Renal Tubular Epithelial Cells.

Yang Y, Li C, Gu X, Zhen J, Zhu S, Lv T, Wan Q, Liu Y
Frontiers in cell and developmental biology 2021;9:700195

A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.

Sun D, Niu Z, Zheng HX, Wu F, Jiang L, Han TQ, Wei Y, Wang J, Jin L
Cellular and molecular gastroenterology and hepatology 2021;11(4):1211-1226.e15

Biochanin A Inhibits Glioblastoma Growth via Restricting Glycolysis and Mitochondrial Oxidative Phosphorylation.

Dong Q, Li Q, Duan L, Yin H, Wang X, Liu Y, Wang B, Li K, Yao X, Yuan G, Pan Y
Frontiers in oncology 2021;11:652008

Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival.

Lowden C, Boulet A, Boehler NA, Seecharran S, Rios Garcia J, Lowe NJ, Liu J, Ong JLK, Wang W, Ma L, Cheng AH, Senatore A, Monks DA, Liu BH, Leary SC, Cheng HM
Cell reports 2021 Sep 14;36(11):109704

A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.

Hasenbilige, Mei J, Dlamini MB, Gao Z, Jiang L, Li Q, Geng C, Shi X, Liu Y, Kong Y, Cao J
Toxicology 2021 Oct;462:152928

Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells.

Xie QE, Wang MY, Cao ZP, Du X, Ji DM, Liang D, Cao YX, Liu YJ
Mitochondrion 2021 Nov;61:44-53

Comparison of the major cell populations among osteoarthritis, Kashin-Beck disease and healthy chondrocytes by single-cell RNA-seq analysis.

Wang X, Ning Y, Zhang P, Poulet B, Huang R, Gong Y, Hu M, Li C, Zhou R, Lammi MJ, Guo X
Cell death & disease 2021 May 27;12(6):551

Extracellular Tuning of Mitochondrial Respiration Leads to Aortic Aneurysm.

Oller J, Gabandé-Rodríguez E, Ruiz-Rodríguez MJ, Desdín-Micó G, Aranda JF, Rodrigues-Diez R, Ballesteros-Martínez C, Blanco EM, Roldan-Montero R, Acuña P, Forteza Gil A, Martín-López CE, Nistal JF, Lino Cardenas CL, Lindsay ME, Martín-Ventura JL, Briones AM, Redondo JM, Mittelbrunn M
Circulation 2021 May 25;143(21):2091-2109

Mitochondrial functional resilience after TFAM ablation in the adult heart.

Ghazal N, Peoples JN, Mohiuddin TA, Kwong JQ
American journal of physiology. Cell physiology 2021 Jun 1;320(6):C929-C942

Mechanistic insights into mitochondrial tRNA(Ala) 3'-end metabolism deficiency.

Ji Y, Nie Z, Meng F, Hu C, Chen H, Jin L, Chen M, Zhang M, Zhang J, Liang M, Wang M, Guan MX
The Journal of biological chemistry 2021 Jul;297(1):100816

Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction.

Condon KJ, Orozco JM, Adelmann CH, Spinelli JB, van der Helm PW, Roberts JM, Kunchok T, Sabatini DM
Proceedings of the National Academy of Sciences of the United States of America 2021 Jan 26;118(4)

Deficiency of β-carotene oxygenase 2 induces mitochondrial fragmentation and activates the STING-IRF3 pathway in the mouse hypothalamus.

Wu L, Guo X, Wong SY, Lu P, Hartson SD, Medeiros DM, Wang W, Clarke SL, Lucas EA, Smith BJ, Chowanadisai W, Lin D
The Journal of nutritional biochemistry 2021 Feb;88:108542

Spermine Protects Cardiomyocytes from High Glucose-Induced Energy Disturbance by Targeting the CaSR-gp78-Ubiquitin Proteasome System.

Wang Y, Wang Y, Li F, Zhang X, Li H, Yang G, Xu C, Wei C
Cardiovascular drugs and therapy 2021 Feb;35(1):73-85

Transcription of MRPL12 regulated by Nrf2 contributes to the mitochondrial dysfunction in diabetic kidney disease.

Gu X, Liu Y, Wang N, Zhen J, Zhang B, Hou S, Cui Z, Wan Q, Feng H
Free radical biology & medicine 2021 Feb 20;164:329-340

Adverse effect of superoxide-induced mitochondrial damage in granulosa cells on follicular development in mouse ovaries.

Hoque SAM, Umehara T, Kawai T, Shimada M
Free radical biology & medicine 2021 Feb 1;163:344-355

Complex I mutations synergize to worsen the phenotypic expression of Leber's hereditary optic neuropathy.

Ji Y, Zhang J, Lu Y, Yi Q, Chen M, Xie S, Mao X, Xiao Y, Meng F, Zhang M, Yang R, Guan MX
The Journal of biological chemistry 2020 Sep 18;295(38):13224-13238

MCART1/SLC25A51 is required for mitochondrial NAD transport.

Kory N, Uit de Bos J, van der Rijt S, Jankovic N, Güra M, Arp N, Pena IA, Prakash G, Chan SH, Kunchok T, Lewis CA, Sabatini DM
Science advances 2020 Oct;6(43)

Ursodeoxycholic acid protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction through acting on ALDH1L2.

Yang Y, Liu S, Gao H, Wang P, Zhang Y, Zhang A, Jia Z, Huang S
Free radical biology & medicine 2020 May 20;152:821-837

Mitochondrial miR-181a-5p promotes glucose metabolism reprogramming in liver cancer by regulating the electron transport chain.

Zhuang X, Chen Y, Wu Z, Xu Q, Chen M, Shao M, Cao X, Zhou Y, Xie M, Shi Y, Zeng Y, Bu H
Carcinogenesis 2020 Jul 14;41(7):972-983

Single-Cell Transcriptomic Atlas of Primate Ovarian Aging.

Wang S, Zheng Y, Li J, Yu Y, Zhang W, Song M, Liu Z, Min Z, Hu H, Jing Y, He X, Sun L, Ma L, Esteban CR, Chan P, Qiao J, Zhou Q, Izpisua Belmonte JC, Qu J, Tang F, Liu GH
Cell 2020 Feb 6;180(3):585-600.e19

SQSTM1/p62 Controls mtDNA Expression and Participates in Mitochondrial Energetic Adaption via MRPL12.

Ma Y, Zhu S, Lv T, Gu X, Feng H, Zhen J, Xin W, Wan Q
iScience 2020 Aug 21;23(8):101428

Gene Expression and Protein Synthesis in Mitochondria Enhance the Duration of High-Speed Linear Motility in Boar Sperm.

Zhu Z, Umehara T, Okazaki T, Goto M, Fujita Y, Hoque SAM, Kawai T, Zeng W, Shimada M
Frontiers in physiology 2019;10:252

Negative effects of ROS generated during linear sperm motility on gene expression and ATP generation in boar sperm mitochondria.

Zhu Z, Kawai T, Umehara T, Hoque SAM, Zeng W, Shimada M
Free radical biology & medicine 2019 Sep;141:159-171

MiR-1a-3p mitigates isoproterenol-induced heart failure by enhancing the expression of mitochondrial ND1 and COX1.

He R, Ding C, Yin P, He L, Xu Q, Wu Z, Shi Y, Su L
Experimental cell research 2019 May 1;378(1):87-97

Contribution of mitochondrial ND1 3394T>C mutation to the phenotypic manifestation of Leber's hereditary optic neuropathy.

Ji Y, Zhang J, Yu J, Wang Y, Lu Y, Liang M, Li Q, Jin X, Wei Y, Meng F, Gao Y, Cang X, Tong Y, Liu X, Zhang M, Jiang P, Zhu T, Mo JQ, Huang T, Jiang P, Guan MX
Human molecular genetics 2019 May 1;28(9):1515-1529

The combination of metformin and 2-deoxyglucose significantly inhibits cyst formation in miniature pigs with polycystic kidney disease.

Lian X, Wu X, Li Z, Zhang Y, Song K, Cai G, Li Q, Lin S, Chen X, Bai XY
British journal of pharmacology 2019 Mar;176(5):711-724

Mitochondrial Protein Turnover Is Critical for Granulosa Cell Proliferation and Differentiation in Antral Follicles.

Hoque SAM, Kawai T, Zhu Z, Shimada M
Journal of the Endocrine Society 2019 Feb 1;3(2):324-339

Protective effects of β- nicotinamide adenine dinucleotide against motor deficits and dopaminergic neuronal damage in a mouse model of Parkinson's disease.

Shan C, Gong YL, Zhuang QQ, Hou YF, Wang SM, Zhu Q, Huang GR, Tao B, Sun LH, Zhao HY, Li ST, Liu JM
Progress in neuro-psychopharmacology & biological psychiatry 2019 Aug 30;94:109670

Exogenous H(2)S reduces the acetylation levels of mitochondrial respiratory enzymes via regulating the NAD(+)-SIRT3 pathway in cardiac tissues of db/db mice.

Sun Y, Teng Z, Sun X, Zhang L, Chen J, Wang B, Lu F, Liu N, Yu M, Peng S, Wang Y, Zhao D, Zhao Y, Ren H, Cheng Z, Dong S, Lu F, Zhang W
American journal of physiology. Endocrinology and metabolism 2019 Aug 1;317(2):E284-E297

Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.

Aulas A, Lyons SM, Fay MM, Anderson P, Ivanov P
Cell death & disease 2018 Nov 13;9(11):1129

Protein Kinase A/CREB Signaling Prevents Adriamycin-Induced Podocyte Apoptosis via Upregulation of Mitochondrial Respiratory Chain Complexes.

Xie K, Zhu M, Xiang P, Chen X, Kasimumali A, Lu R, Wang Q, Mou S, Ni Z, Gu L, Pang H
Molecular and cellular biology 2018 Jan 1;38(1)

Subunit composition of respiratory chain complex 1 and its responses to oxygen in mitochondria from human donor livers.

Khorsandi SE, Taanman JW, Heaton N
BMC research notes 2017 Nov 2;10(1):547

Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway.

Wang Y, Gao P, Wei C, Li H, Zhang L, Zhao Y, Wu B, Tian Y, Zhang W, Wu L, Wang R, Xu C
Cell death & disease 2017 May 18;8(5):e2799

The changes in glucose metabolism and cell proliferation in the kidneys of polycystic kidney disease mini-pig models.

Lian X, Zhao J, Wu X, Zhang Y, Li Q, Lin S, Bai XY, Chen X
Biochemical and biophysical research communications 2017 Jun 24;488(2):374-381

Non-cytotoxic concentrations of acetaminophen induced mitochondrial biogenesis and antioxidant response in HepG2 cells.

Zhang T, Zhang Q, Guo J, Yuan H, Peng H, Cui L, Yin J, Zhang L, Zhao J, Li J, White A, Carmichael PL, Westmoreland C, Peng S
Environmental toxicology and pharmacology 2016 Sep;46:71-79

A LON-ClpP Proteolytic Axis Degrades Complex I to Extinguish ROS Production in Depolarized Mitochondria.

Pryde KR, Taanman JW, Schapira AH
Cell reports 2016 Dec 6;17(10):2522-2531

EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer.

Zhang J, Wang C, Chen X, Takada M, Fan C, Zheng X, Wen H, Liu Y, Wang C, Pestell RG, Aird KM, Kaelin WG Jr, Liu XS, Zhang Q
The EMBO journal 2015 Dec 2;34(23):2953-70

MicroRNA directly enhances mitochondrial translation during muscle differentiation.

Zhang X, Zuo X, Yang B, Li Z, Xue Y, Zhou Y, Huang J, Zhao X, Zhou J, Yan Y, Zhang H, Guo P, Sun H, Guo L, Zhang Y, Fu XD
Cell 2014 Jul 31;158(3):607-19

iTRAQ-based proteomic analysis of dioscin on human HCT-116 colon cancer cells.

Chen H, Xu L, Yin L, Xu Y, Han X, Qi Y, Zhao Y, Liu K, Peng J
Proteomics 2014 Jan;14(1):51-73

No comments: Submit comment

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: mouse liver tissue were subjected to SDS PAGE followed by western blot with 19703-1-AP(ND1 antibody) at dilution of 1:1000
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The ND1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human ND1. This antibody recognizes human, mouse antigen. The ND1 antibody has been validated for the following applications: ELISA, WB, IF, IHC analysis.
Appendix: 19703-1-AP.pdf

: Show more