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- Antibody Data
- Antigen structure
- References [116]
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- Product number
- 12208-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12208-1-AP, RRID:AB_2245417
- Product name
- CREB1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CREB1 antibody (Cat. #12208-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, monkey and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Neuroprotective effects of polyphyllin VI against rotenone-induced toxicity in SH-SY5Y cells.
The miR-3074/BMP7 axis regulates TGF-β-caused activation of hepatic stellate cells in vitro and CCl(4)-caused murine liver fibrosis in vivo.
Reprimo (RPRM) mediates neuronal ferroptosis via CREB-Nrf2/SCD1 pathways in radiation-induced brain injury.
Maresin 1 Activates LGR6 to Alleviate Neuroinflammation via the CREB/JMJD3/IRF4 Pathway in a Rat Model of Subarachnoid Hemorrhage.
Naoxinqing tablet protects against cerebral ischemic/reperfusion injury by regulating ampkα/NAMPT/SIRT1/PGC-1α pathway.
Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis.
GPR39 Agonist TC-G 1008 Promoted Mitochondrial Biogenesis and Improved Antioxidative Capability via CREB/PGC-1α Pathway Following Intracerebral Hemorrhage in Mice.
BNC1 deficiency induces mitochondrial dysfunction-triggered spermatogonia apoptosis through the CREB/SIRT1/FOXO3 pathway: the therapeutic potential of nicotinamide riboside and metformin†.
Achyranthes bidentata polysaccharide ameliorates type 2 diabetes mellitus by gut microbiota-derived short-chain fatty acids-induced activation of the GLP-1/GLP-1R/cAMP/PKA/CREB/INS pathway.
CREB1 Silencing Protects Against Inflammatory Response in Rats with Deep Vein Thrombosis Through Reducing RPL9 Expression and Blocking NF-κB Signaling.
Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition.
Osr2 functions as a biomechanical checkpoint to aggravate CD8(+) T cell exhaustion in tumor.
CENPN suppresses autophagy and increases paclitaxel resistance in nasopharyngeal carcinoma cells by inhibiting the CREB-VAMP8 signaling axis.
Intranasal Delivery of Near-Infrared and Magnetic Dual-Response Nanospheres to Rapidly Produce Antidepressant-Like and Cognitive Enhancement Effects.
miR-377-3p Regulates Hippocampal Neurogenesis via the Zfp462-Pbx1 Pathway and Mediates Anxiety-Like Behaviors in Prenatal Hypoxic Offspring.
Isorhamnetin Downregulates MMP2 and MMP9 to Inhibit Development of Rheumatoid Arthritis through SRC/ERK/CREB Pathway.
The prenatal use of agmatine prevents social behavior deficits in VPA-exposed mice by activating the ERK/CREB/BDNF signaling pathway.
The PKA-CREB1 axis regulates coronavirus proliferation by viral helicase nsp13 association.
Vitronectin Destroyed Intestinal Epithelial Cell Differentiation through Activation of PDE4-Mediated Ferroptosis in Inflammatory Bowel Disease.
Chronic stress promotes colorectal cancer progression by enhancing glycolysis through β2-AR/CREB1 signal pathway.
A short peptide LINC00665_18aa encoded by lncRNA LINC00665 suppresses the proliferation and migration of osteosarcoma cells through the regulation of the CREB1/RPS6KA3 interaction.
Integrating Network Pharmacology, Molecular Docking and Pharmacological Evaluation for Exploring the Polyrhachis vicina Rogers in Ameliorating Depression.
The SIK1/CRTC2/CREB1 and TWIST1/PI3K/Akt/GSK3β signaling pathways mediated by microRNA-25-3p are altered in the schizophrenic rat brain.
The Chinese herbal medicine Dai-Zong-Fang promotes browning of white adipocytes in vivo and in vitro by activating PKA pathway to ameliorate obesity.
Lactate modulates iron metabolism by binding soluble adenylyl cyclase.
Human umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice.
Protective Effects of ζ-Carotene-like Compounds against Acute UVB-Induced Skin Damage.
Long non-coding RNA PFI inhibits apoptosis of alveolar epithelial cells to alleviate lung injury via miR-328-3p/Creb1 axis.
The crucial role that hippocampus Cyclooxygenase-2 plays in memory.
Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain.
Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter.
TET2 is recruited by CREB to promote Cebpb, Cebpa, and Pparg transcription by facilitating hydroxymethylation during adipocyte differentiation.
LncRNA CASC19 promotes gastric cancer progression through preventing CREB1 protein ubiquitin/proteasome-dependent degradation.
Norepinephrine/β(2)-Adrenergic Receptor Pathway Promotes the Cell Proliferation and Nerve Growth Factor Production in Triple-Negative Breast Cancer.
LKB1 controls inflammatory potential through CRTC2-dependent histone acetylation.
ZNRF2 as an oncogene is transcriptionally regulated by CREB1 in breast cancer models.
Downregulated CAV-1 in mouse spinal cord may alleviate bone cancer pain by inhibiting the ERK/CREB pathway.
Exposure to dithiocarbamate fungicide maneb in vitro and in vivo: Neuronal apoptosis and underlying mechanisms.
Bisphenol A and Di(2-Ethylhexyl) Phthalate promote pulmonary carcinoma in female rats via estrogen receptor beta: In vivo and in silico analysis.
Dysfunctional microRNA-144-3p/ZBTB20/ERK/CREB1 signalling pathway is associated with MK-801-induced schizophrenia-like abnormalities.
Upregulated GPRC5A disrupting the Hippo pathway promotes the proliferation and migration of pancreatic cancer cells via the cAMP-CREB axis.
Tunicamycin induces depression-like behaviors in male rats, accompanied by initiated chaperon-mediated autophagy and decreased synaptic protein expression in the hippocampus.
Mailuoning oral liquid attenuates convalescent cerebral ischemia by inhibiting AMPK/mTOR-associated apoptosis and promoting CREB/BDNF-mediated neuroprotection.
Cdo1-Camkk2-AMPK axis confers the protective effects of exercise against NAFLD in mice.
Benzene, 1,2,4-Trimethoxy-5-(2-Methyl-1-Propen-1-yl) Attenuates D-galactose/AlCl(3)-induced Cognitive Impairment by Inhibiting Inflammation, Apoptosis, and improving Expression of Memory-Related Proteins.
Nitration of cAMP-Response Element Binding Protein Participates in Myocardial Infarction-Induced Myocardial Fibrosis via Accelerating Transcription of Col1a2 and Cxcl12.
The asymmetrical ESR1 signaling in muscle progenitor cells determines the progression of adolescent idiopathic scoliosis.
Cadmium-induced Sertoli Cell Injury Through p38-MAPK and Related Signaling Proteins-A Study by RNA Sequencing.
Dopamine D1 receptor activation ameliorates ox-LDL-induced endothelial cell senescence via CREB/Nrf2 pathway.
Pseudoephedrine Nanoparticles Alleviate Adriamycin-Induced Reproductive Toxicity Through the GnRhR Signaling Pathway.
Parathyroid hormone alleviates non-alcoholic liver steatosis via activating the hepatic cAMP/PKA/CREB pathway.
Nrf2 Overexpression Decreases Vincristine Chemotherapy Sensitivity Through the PI3K-AKT Pathway in Adult B-Cell Acute Lymphoblastic Leukemia.
Upregulation of Neogenin-1 by a CREB1-BAF47 Complex in Vascular Endothelial Cells is Implicated in Atherogenesis.
Cannabidiol attenuates methamphetamine-induced cardiac inflammatory response through the PKA/CREB pathway in rats.
A 3D-printed molybdenum-containing scaffold exerts dual pro-osteogenic and anti-osteoclastogenic effects to facilitate alveolar bone repair.
Yangjing Zhongyu decoction facilitates mitochondrial activity, estrogenesis, and energy metabolism in H(2)O(2)-induced human granulosa cell line KGN.
Antidepressant effect of Jujuboside A on corticosterone-induced depression in mice.
Maizediterpene D from the roots of Zea mays L. alleviates hydrogen peroxide induced oxidative stress and improves cell survival by activation of TrkB/IGF-1R crosstalk pathways.
Upregulation of Periostin Through CREB Participates in Myocardial Infarction-induced Myocardial Fibrosis.
Inhibition of translocator protein 18 kDa suppressed the progression of glioma via the ELAV-like RNA-binding protein 1/MAPK-activated protein kinase 3 axis.
Kinase activity profiling identifies putative downstream targets of cGMP/PKG signaling in inherited retinal neurodegeneration.
CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m(6)A-modified CREB1 mRNA.
A novel phosphodiesterase 9A inhibitor LW33 protects against ischemic stroke through the cGMP/PKG/CREB pathway.
Metabotropic glutamate receptor 5 upregulation of γ-aminobutyric acid transporter 3 expression ameliorates cognitive impairment after traumatic brain injury in mice.
The role and mechanism of TLR4-siRNA in the impairment of learning and memory in young mice induced by isoflurane.
The BDNF-TrkB-CREB Signalling Pathway Is Involved in Bisphenol S-Induced Neurotoxicity in Male Mice by Regulating Methylation.
Gestational exposure to fluoride impairs cognition in C57 BL/6 J male offspring mice via the p-Creb1-BDNF-TrkB signaling pathway.
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
Pan-cancer multi-omics analyses reveal crosstalk between the Hippo and immune signaling pathways in the tumor microenvironment.
WT1 suppresses follicle-stimulating hormone-induced progesterone secretion by regulating ERK1/2 pathway in chicken preovulatory granulosa cells.
Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP/PKA signaling pathway in human trophoblastic HTR-8/Svneo cells.
Downregulation of IL-8 and IL-10 by the Activation of Ca(2+)-Activated K(+) Channel K(Ca)3.1 in THP-1-Derived M(2) Macrophages.
Systematic Survey of the Regulatory Networks of the Long Noncoding RNA BANCR in Cervical Cancer Cells.
m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis.
CREB Ameliorates Osteoarthritis Progression Through Regulating Chondrocytes Autophagy via the miR-373/METTL3/TFEB Axis.
CREB1 and ATF1 Negatively Regulate Glutathione Biosynthesis Sensitizing Cells to Oxidative Stress.
LncRNA H19 Upregulation Participates in the Response of Glioma Cells to Radiation.
GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic-Pituitary-Adrenal Axis Hyperactivity.
Edaravone Alleviated Propofol-Induced Neurotoxicity in Developing Hippocampus by mBDNF/TrkB/PI3K Pathway.
A Potential Mechanism Underlying the Therapeutic Effects of Progesterone and Allopregnanolone on Ketamine-Induced Cognitive Deficits.
An Integrative Pharmacology-Based Strategy to Uncover the Mechanism of Xiong-Pi-Fang in Treating Coronary Heart Disease with Depression.
KDELR2 promotes breast cancer proliferation via HDAC3-mediated cell cycle progression.
Adenylyl cyclase 3 regulates osteocyte mechanotransduction and primary cilium.
miR-221/222 suppression induced by activation of the cAMP/PKA/CREB1 pathway is required for cAMP-induced bidirectional differentiation of glioma cells.
Role of the BDNF/TrkB/CREB signaling pathway in the cytotoxicity of bisphenol S in SK-N-SH cells.
Congenital hypothyroidism impairs spine growth of dentate granule cells by downregulation of CaMKIV.
A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone.
Uncaria rhynchophylla ameliorates unpredictable chronic mild stress-induced depression in mice via activating 5-HT(1A) receptor: Insights from transcriptomics.
Rapid antidepressant-like effect of Fructus Aurantii depends on cAMP-response element binding protein/Brain-derived neurotrophic facto by mediating synaptic transmission.
Glycogen synthase kinase-3β inhibitor SB216763 promotes DNA repair in ischemic retinal neurons.
mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.
Duzhong Butiansu Prescription Improves Heat Stress-Induced Spermatogenic Dysfunction by Regulating Sperm Formation and Heat Stress Pathway.
LncRNA BLACAT1/miR-519d-3p/CREB1 Axis Mediates Proliferation, Apoptosis, Migration, Invasion, and Drug-Resistance in Colorectal Cancer Progression.
Homer1a Undergoes Bimodal Transcriptional Regulation by CREB and the Circadian Clock.
Anti-Alzheimer's disease activity of secondary metabolites from Xanthoceras sorbifolia Bunge.
Bexarotene Improve Depression-Like Behaviour in Mice by Protecting Against Neuro-inflammation and Synaptic Damage.
LncRNA MALAT1 inhibits apoptosis of endometrial stromal cells through miR-126-5p-CREB1 axis by activating PI3K-AKT pathway.
Down-Regulated CUEDC2 Increases GDNF Expression by Stabilizing CREB Through Reducing Its Ubiquitination in Glioma.
Saikosaponin-d impedes hippocampal neurogenesis and causes cognitive deficits by inhibiting the survival of neural stem/progenitor cells via neurotrophin receptor signaling in mice.
PTEN participates in airway remodeling of asthma by regulating CD38/Ca(2+)/CREB signaling.
The potential role of Krüppel-like factor 13 (Aj-klf13) in the intestine regeneration of sea cucumber Apostichopus japonicus.
MicroRNA-23a-3p Inhibits Mucosal Melanoma Growth and Progression through Targeting Adenylate Cyclase 1 and Attenuating cAMP and MAPK Pathways.
CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress.
ZNF436 promotes tumor cell proliferation through transcriptional activation of BCL10 in glioma.
Metformin Modulates High Glucose-Incubated Human Umbilical Vein Endothelial Cells Proliferation and Apoptosis Through AMPK/CREB/BDNF Pathway.
Neurotoxicity, behavioral changes and gene-expression profile of mice exposed to SnS(2) nanoflowers.
Calretinin Participates in Regulating Steroidogenesis by PLC-Ca(2+)-PKC Pathway in Leydig Cells.
Analysis of the oncogene BRAF mutation and the correlation of the expression of wild-type BRAF and CREB1 in endometriosis.
Effects of fluoride on synapse morphology and myelin damage in mouse hippocampus.
Inhibition of Acid Sensing Ion Channel 3 Aggravates Seizures by Regulating NMDAR Function.
A CREB1/miR-433 reciprocal feedback loop modulates proliferation and metastasis in colorectal cancer.
Icariin Attenuates Synaptic and Cognitive Deficits in an Aβ(1-42)-Induced Rat Model of Alzheimer's Disease.
Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol-induced steatosis.
Epicatechin Plus Treadmill Exercise are Neuroprotective Against Moderate-stage Amyloid Precursor Protein/Presenilin 1 Mice.
LncRNA-UCA1 enhances cell proliferation and 5-fluorouracil resistance in colorectal cancer by inhibiting miR-204-5p.
BDNF-dependent recycling facilitates TrkB translocation to postsynaptic density during LTP via a Rab11-dependent pathway.
Li L, Chen Z, Hao C
Brain research 2024 May 1;1830:148824
Brain research 2024 May 1;1830:148824
The miR-3074/BMP7 axis regulates TGF-β-caused activation of hepatic stellate cells in vitro and CCl(4)-caused murine liver fibrosis in vivo.
Liu B, Xie X, Yang X, Dou C, Tang H, Liu J
Human cell 2024 Mar;37(2):435-450
Human cell 2024 Mar;37(2):435-450
Reprimo (RPRM) mediates neuronal ferroptosis via CREB-Nrf2/SCD1 pathways in radiation-induced brain injury.
Shi W, Wang J, Li Z, Xu S, Wang J, Zhang L, Yang H
Free radical biology & medicine 2024 Mar;213:343-358
Free radical biology & medicine 2024 Mar;213:343-358
Maresin 1 Activates LGR6 to Alleviate Neuroinflammation via the CREB/JMJD3/IRF4 Pathway in a Rat Model of Subarachnoid Hemorrhage.
Li Z, Yuan W, Yang X, Jiang J, Zhang QL, Yan XX, Zuo YC
Neuroscience 2024 Mar 26;542:21-32
Neuroscience 2024 Mar 26;542:21-32
Naoxinqing tablet protects against cerebral ischemic/reperfusion injury by regulating ampkα/NAMPT/SIRT1/PGC-1α pathway.
Sun X, Pan Y, Luo Y, Guo H, Zhang Z, Wang D, Li C, Sun X
Journal of ethnopharmacology 2024 Mar 25;322:117672
Journal of ethnopharmacology 2024 Mar 25;322:117672
Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis.
Zhao Y, Ning J, Teng H, Deng Y, Sheldon M, Shi L, Martinez C, Zhang J, Tian A, Sun Y, Nakagawa S, Yao F, Wang H, Ma L
Nature communications 2024 Mar 16;15(1):2384
Nature communications 2024 Mar 16;15(1):2384
GPR39 Agonist TC-G 1008 Promoted Mitochondrial Biogenesis and Improved Antioxidative Capability via CREB/PGC-1α Pathway Following Intracerebral Hemorrhage in Mice.
Zhang Z, Yuan Y, Zhang X, Gu L, Tang Y, Zhao Y, Dai J, Tao Y, Xie Z
Translational stroke research 2024 Mar 15;
Translational stroke research 2024 Mar 15;
BNC1 deficiency induces mitochondrial dysfunction-triggered spermatogonia apoptosis through the CREB/SIRT1/FOXO3 pathway: the therapeutic potential of nicotinamide riboside and metformin†.
Ni F, Wang F, Li J, Liu Y, Sun X, Chen J, Li J, Zhang Y, Jin J, Ye X, Tu M, Chen J, Chen C, Zhang D
Biology of reproduction 2024 Mar 13;110(3):615-631
Biology of reproduction 2024 Mar 13;110(3):615-631
Achyranthes bidentata polysaccharide ameliorates type 2 diabetes mellitus by gut microbiota-derived short-chain fatty acids-induced activation of the GLP-1/GLP-1R/cAMP/PKA/CREB/INS pathway.
Xia T, He W, Luo Z, Wang K, Tan X
International journal of biological macromolecules 2024 Jun;270(Pt 2):132256
International journal of biological macromolecules 2024 Jun;270(Pt 2):132256
CREB1 Silencing Protects Against Inflammatory Response in Rats with Deep Vein Thrombosis Through Reducing RPL9 Expression and Blocking NF-κB Signaling.
Jian X, Yang D, Wang L, Wang H
Journal of cardiovascular translational research 2024 Jun;17(3):570-584
Journal of cardiovascular translational research 2024 Jun;17(3):570-584
Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition.
Li T, Wei L, Zhang X, Fu B, Zhou Y, Yang M, Cao M, Chen Y, Tan Y, Shi Y, Wu L, Xuan C, Du Q, Hu R
Molecular cancer research : MCR 2024 Jun 4;22(6):538-554
Molecular cancer research : MCR 2024 Jun 4;22(6):538-554
Osr2 functions as a biomechanical checkpoint to aggravate CD8(+) T cell exhaustion in tumor.
Zhang J, Li J, Hou Y, Lin Y, Zhao H, Shi Y, Chen K, Nian C, Tang J, Pan L, Xing Y, Gao H, Yang B, Song Z, Cheng Y, Liu Y, Sun M, Linghu Y, Li J, Huang H, Lai Z, Zhou Z, Li Z, Sun X, Chen Q, Su D, Li W, Peng Z, Liu P, Chen W, Huang H, Chen Y, Xiao B, Ye L, Chen L, Zhou D
Cell 2024 Jun 20;187(13):3409-3426.e24
Cell 2024 Jun 20;187(13):3409-3426.e24
CENPN suppresses autophagy and increases paclitaxel resistance in nasopharyngeal carcinoma cells by inhibiting the CREB-VAMP8 signaling axis.
Wang BR, Han JB, Jiang Y, Xu S, Yang R, Kong YG, Tao ZZ, Hua QQ, Zou Y, Chen SM
Autophagy 2024 Feb;20(2):329-348
Autophagy 2024 Feb;20(2):329-348
Intranasal Delivery of Near-Infrared and Magnetic Dual-Response Nanospheres to Rapidly Produce Antidepressant-Like and Cognitive Enhancement Effects.
Hu J, Lian Z, Weng Z, Xu Z, Gao J, Liu Y, Luo T, Wang X
Advanced materials (Deerfield Beach, Fla.) 2024 Aug;36(31):e2405547
Advanced materials (Deerfield Beach, Fla.) 2024 Aug;36(31):e2405547
miR-377-3p Regulates Hippocampal Neurogenesis via the Zfp462-Pbx1 Pathway and Mediates Anxiety-Like Behaviors in Prenatal Hypoxic Offspring.
Wang B, Zhu Y, Wei B, Zeng H, Zhang P, Li L, Wang H, Wu X, Zheng Y, Sun M
Molecular neurobiology 2024 Apr;61(4):1920-1935
Molecular neurobiology 2024 Apr;61(4):1920-1935
Isorhamnetin Downregulates MMP2 and MMP9 to Inhibit Development of Rheumatoid Arthritis through SRC/ERK/CREB Pathway.
Liu XR, Li SF, Mei WY, Liu XD, Zhou RB
Chinese journal of integrative medicine 2024 Apr;30(4):299-310
Chinese journal of integrative medicine 2024 Apr;30(4):299-310
The prenatal use of agmatine prevents social behavior deficits in VPA-exposed mice by activating the ERK/CREB/BDNF signaling pathway.
Chen S, Xu Q, Zhao L, Zhang M, Xu H
Birth defects research 2024 Apr;116(4):e2336
Birth defects research 2024 Apr;116(4):e2336
The PKA-CREB1 axis regulates coronavirus proliferation by viral helicase nsp13 association.
Zheng T, Shen B, Bai Y, Li E, Zhang X, Hu Y, Gao T, Dong Q, Zhu L, Jin R, Shi H, Liu H, Gao Y, Liu X, Cao C
Journal of virology 2024 Apr 16;98(4):e0156523
Journal of virology 2024 Apr 16;98(4):e0156523
Vitronectin Destroyed Intestinal Epithelial Cell Differentiation through Activation of PDE4-Mediated Ferroptosis in Inflammatory Bowel Disease.
Pan W, Xiang L, Liang X, Du W, Zhao J, Zhang S, Zhou X, Geng L, Gong S, Xu W
Mediators of inflammation 2023;2023:6623329
Mediators of inflammation 2023;2023:6623329
Chronic stress promotes colorectal cancer progression by enhancing glycolysis through β2-AR/CREB1 signal pathway.
Guan Y, Yao W, Yu H, Feng Y, Zhao Y, Zhan X, Wang Y
International journal of biological sciences 2023;19(7):2006-2019
International journal of biological sciences 2023;19(7):2006-2019
A short peptide LINC00665_18aa encoded by lncRNA LINC00665 suppresses the proliferation and migration of osteosarcoma cells through the regulation of the CREB1/RPS6KA3 interaction.
Pan J, Liu M, Duan X, Wang D
PloS one 2023;18(6):e0286422
PloS one 2023;18(6):e0286422
Integrating Network Pharmacology, Molecular Docking and Pharmacological Evaluation for Exploring the Polyrhachis vicina Rogers in Ameliorating Depression.
He J, Han D, Jia C, Xie J, Zhu F, Wei J, Li D, Wei D, Li Y, Tang L, Wei G, Yan J, Tong Y, Yang L, Tan X
Drug design, development and therapy 2023;17:717-735
Drug design, development and therapy 2023;17:717-735
The SIK1/CRTC2/CREB1 and TWIST1/PI3K/Akt/GSK3β signaling pathways mediated by microRNA-25-3p are altered in the schizophrenic rat brain.
Pan B, Zhu X, Han B, Weng J, Wang Y, Liu Y
Frontiers in cellular neuroscience 2023;17:1087335
Frontiers in cellular neuroscience 2023;17:1087335
The Chinese herbal medicine Dai-Zong-Fang promotes browning of white adipocytes in vivo and in vitro by activating PKA pathway to ameliorate obesity.
Xu J, Zhang LW, Feng H, Tang Y, Fu SQ, Liu XM, Zhu XY
Frontiers in pharmacology 2023;14:1176443
Frontiers in pharmacology 2023;14:1176443
Lactate modulates iron metabolism by binding soluble adenylyl cyclase.
Liu W, Zhang S, Li Q, Wu Y, Jia X, Feng W, Li Z, Shi Y, Hou Q, Ma J, Liu Y, Gao P, Ganz T, Liu S
Cell metabolism 2023 Sep 5;35(9):1597-1612.e6
Cell metabolism 2023 Sep 5;35(9):1597-1612.e6
Human umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice.
Wei P, Jia M, Kong X, Lyu W, Feng H, Sun X, Li J, Yang JJ
Stem cell research & therapy 2023 Sep 21;14(1):263
Stem cell research & therapy 2023 Sep 21;14(1):263
Protective Effects of ζ-Carotene-like Compounds against Acute UVB-Induced Skin Damage.
Zhang L, Liang S, Zhang Z, Wang K, Cao J, Yao M, Qin L, Qu C, Miao J
International journal of molecular sciences 2023 Sep 12;24(18)
International journal of molecular sciences 2023 Sep 12;24(18)
Long non-coding RNA PFI inhibits apoptosis of alveolar epithelial cells to alleviate lung injury via miR-328-3p/Creb1 axis.
Li Z, Jin T, Yang R, Guo J, Niu Z, Gao H, Song X, Zhang Q, Ning Z, Ren L, Wang Y, Fan X, Liang H, Li T, He W
Experimental cell research 2023 Sep 1;430(1):113685
Experimental cell research 2023 Sep 1;430(1):113685
The crucial role that hippocampus Cyclooxygenase-2 plays in memory.
Ni H, Guo Z, Wu Y, Wang J, Yang Y, Zhu Z, Wang D
The European journal of neuroscience 2023 Nov;58(10):4123-4136
The European journal of neuroscience 2023 Nov;58(10):4123-4136
Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain.
Zhou HY, Feng X, Wang LW, Zhou R, Sun H, Chen X, Lu RB, Huang Y, Guo Q, Luo XH
Cell metabolism 2023 Nov 7;35(11):1915-1930.e8
Cell metabolism 2023 Nov 7;35(11):1915-1930.e8
Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter.
Gioia MD, Poli V, Tan PJ, Spreafico R, Chu A, Cuenca AG, Gordts PL, Pandolfi L, Meloni F, Witztum JL, Chou J, Springstead JR, Zanoni I
bioRxiv : the preprint server for biology 2023 Nov 21;
bioRxiv : the preprint server for biology 2023 Nov 21;
TET2 is recruited by CREB to promote Cebpb, Cebpa, and Pparg transcription by facilitating hydroxymethylation during adipocyte differentiation.
Liu Y, He T, Li Z, Sun Z, Wang S, Shen H, Hou L, Li S, Wei Y, Zhuo B, Li S, Zhou C, Guo H, Zhang R, Li B
iScience 2023 Nov 17;26(11):108312
iScience 2023 Nov 17;26(11):108312
LncRNA CASC19 promotes gastric cancer progression through preventing CREB1 protein ubiquitin/proteasome-dependent degradation.
Wang S, Qiao C, Li J, Liu S, Li P
Carcinogenesis 2023 May 27;44(3):209-220
Carcinogenesis 2023 May 27;44(3):209-220
Norepinephrine/β(2)-Adrenergic Receptor Pathway Promotes the Cell Proliferation and Nerve Growth Factor Production in Triple-Negative Breast Cancer.
Jin M, Wang Y, Zhou T, Li W, Wen Q
Journal of breast cancer 2023 Jun;26(3):268-285
Journal of breast cancer 2023 Jun;26(3):268-285
LKB1 controls inflammatory potential through CRTC2-dependent histone acetylation.
Compton SE, Kitchen-Goosen SM, DeCamp LM, Lau KH, Mabvakure B, Vos M, Williams KS, Wong KK, Shi X, Rothbart SB, Krawczyk CM, Jones RG
Molecular cell 2023 Jun 1;83(11):1872-1886.e5
Molecular cell 2023 Jun 1;83(11):1872-1886.e5
ZNRF2 as an oncogene is transcriptionally regulated by CREB1 in breast cancer models.
Liu JT, Sun ZX, Zhong R, Zhang YD, Wang T, Hou YD, Bao JH, Zhang L, Chen B
Human cell 2023 Jul;36(4):1501-1515
Human cell 2023 Jul;36(4):1501-1515
Downregulated CAV-1 in mouse spinal cord may alleviate bone cancer pain by inhibiting the ERK/CREB pathway.
Ge J, Song J, Sun B, Yang X, Du B, Sun X, Zhang J, Ge J, Xie H
Mutation research 2023 Jul-Dec;827:111829
Mutation research 2023 Jul-Dec;827:111829
Exposure to dithiocarbamate fungicide maneb in vitro and in vivo: Neuronal apoptosis and underlying mechanisms.
Liu C, Liu Z, Fang Y, Liao Z, Zhang Z, Yuan X, Yu T, Yang Y, Xiong M, Zhang X, Zhang G, Meng L, Zhang Z
Environment international 2023 Jan;171:107696
Environment international 2023 Jan;171:107696
Bisphenol A and Di(2-Ethylhexyl) Phthalate promote pulmonary carcinoma in female rats via estrogen receptor beta: In vivo and in silico analysis.
Xiao M, Zhang Y, Zhang X, Zhang G, Jin C, Yang J, Wu S, Lu X
Ecotoxicology and environmental safety 2023 Jan 15;250:114496
Ecotoxicology and environmental safety 2023 Jan 15;250:114496
Dysfunctional microRNA-144-3p/ZBTB20/ERK/CREB1 signalling pathway is associated with MK-801-induced schizophrenia-like abnormalities.
Pan B, Han B, Zhu X, Wang Y, Ji H, Weng J, Liu Y
Brain research 2023 Jan 1;1798:148153
Brain research 2023 Jan 1;1798:148153
Upregulated GPRC5A disrupting the Hippo pathway promotes the proliferation and migration of pancreatic cancer cells via the cAMP-CREB axis.
Fang W, Yu X, Deng J, Yu B, Xiong J, Ma M
Discover oncology 2023 Feb 3;14(1):17
Discover oncology 2023 Feb 3;14(1):17
Tunicamycin induces depression-like behaviors in male rats, accompanied by initiated chaperon-mediated autophagy and decreased synaptic protein expression in the hippocampus.
Yuan G, Xiao L, Xie Y, Si L, Xu H, Xu W, Wang G
Neuroscience letters 2023 Feb 28;798:137058
Neuroscience letters 2023 Feb 28;798:137058
Mailuoning oral liquid attenuates convalescent cerebral ischemia by inhibiting AMPK/mTOR-associated apoptosis and promoting CREB/BDNF-mediated neuroprotection.
Liu X, Fan L, Li J, Bai Z, Wang Y, Liu Y, Jiang H, Tao A, Li X, Zhang H, Tan N
Journal of ethnopharmacology 2023 Dec 5;317:116731
Journal of ethnopharmacology 2023 Dec 5;317:116731
Cdo1-Camkk2-AMPK axis confers the protective effects of exercise against NAFLD in mice.
Chen M, Zhu JY, Mu WJ, Luo HY, Li Y, Li S, Yan LJ, Li RY, Guo L
Nature communications 2023 Dec 18;14(1):8391
Nature communications 2023 Dec 18;14(1):8391
Benzene, 1,2,4-Trimethoxy-5-(2-Methyl-1-Propen-1-yl) Attenuates D-galactose/AlCl(3)-induced Cognitive Impairment by Inhibiting Inflammation, Apoptosis, and improving Expression of Memory-Related Proteins.
Yang P, Liao C, Hu Q, Zhang J, Yang H, Xian S, Mao S
Neuroscience 2023 Aug 1;524:242-255
Neuroscience 2023 Aug 1;524:242-255
Nitration of cAMP-Response Element Binding Protein Participates in Myocardial Infarction-Induced Myocardial Fibrosis via Accelerating Transcription of Col1a2 and Cxcl12.
Xue K, Chen S, Chai J, Yan W, Zhu X, Ji D, Wu Y, Liu H, Wang W
Antioxidants & redox signaling 2023 Apr;38(10-12):709-730
Antioxidants & redox signaling 2023 Apr;38(10-12):709-730
The asymmetrical ESR1 signaling in muscle progenitor cells determines the progression of adolescent idiopathic scoliosis.
Shao X, Fu X, Yang J, Sui W, Li S, Yang W, Lin X, Zhang Y, Jia M, Liu H, Liu W, Han L, Yu Y, Deng Y, Zhang T, Yang J, Hu P
Cell discovery 2023 Apr 25;9(1):44
Cell discovery 2023 Apr 25;9(1):44
Cadmium-induced Sertoli Cell Injury Through p38-MAPK and Related Signaling Proteins-A Study by RNA Sequencing.
Wang L, Li X, Bu T, Wu X, Li L, Gao S, Yun D, Zhang Y, Chen H, Sun F, Cheng CY
Endocrinology 2023 Apr 17;164(6)
Endocrinology 2023 Apr 17;164(6)
Dopamine D1 receptor activation ameliorates ox-LDL-induced endothelial cell senescence via CREB/Nrf2 pathway.
Zhao Y, Li Y, Li H, Shi S
Experimental cell research 2023 Apr 15;425(2):113542
Experimental cell research 2023 Apr 15;425(2):113542
Pseudoephedrine Nanoparticles Alleviate Adriamycin-Induced Reproductive Toxicity Through the GnRhR Signaling Pathway.
Fu Y, Yuan P, Zheng Y, Wei Y, Gao L, Ruan Y, Chen Y, Li P, Feng W, Zheng X
International journal of nanomedicine 2022;17:1549-1566
International journal of nanomedicine 2022;17:1549-1566
Parathyroid hormone alleviates non-alcoholic liver steatosis via activating the hepatic cAMP/PKA/CREB pathway.
Feng X, Xiao Y, Guo Q, Peng H, Zhou HY, Wang JP, Xia ZY
Frontiers in endocrinology 2022;13:899731
Frontiers in endocrinology 2022;13:899731
Nrf2 Overexpression Decreases Vincristine Chemotherapy Sensitivity Through the PI3K-AKT Pathway in Adult B-Cell Acute Lymphoblastic Leukemia.
Wang L, Liu X, Kang Q, Pan C, Zhang T, Feng C, Chen L, Wei S, Wang J
Frontiers in oncology 2022;12:876556
Frontiers in oncology 2022;12:876556
Upregulation of Neogenin-1 by a CREB1-BAF47 Complex in Vascular Endothelial Cells is Implicated in Atherogenesis.
Li N, Liu H, Xue Y, Chen J, Kong X, Zhang Y
Frontiers in cell and developmental biology 2022;10:803029
Frontiers in cell and developmental biology 2022;10:803029
Cannabidiol attenuates methamphetamine-induced cardiac inflammatory response through the PKA/CREB pathway in rats.
Nie Q, Dong W, Shen B, Yang G, Yu H, Zhang R, Peng Y, Yu Y, Hong S, Li L
Annals of translational medicine 2022 Sep;10(18):985
Annals of translational medicine 2022 Sep;10(18):985
A 3D-printed molybdenum-containing scaffold exerts dual pro-osteogenic and anti-osteoclastogenic effects to facilitate alveolar bone repair.
Tian B, Li X, Zhang J, Zhang M, Gan D, Deng D, Sun L, He X, Wu C, Chen F
International journal of oral science 2022 Sep 5;14(1):45
International journal of oral science 2022 Sep 5;14(1):45
Yangjing Zhongyu decoction facilitates mitochondrial activity, estrogenesis, and energy metabolism in H(2)O(2)-induced human granulosa cell line KGN.
Liu J, Shi D, Ma Q, Zhao P
Journal of ethnopharmacology 2022 Sep 15;295:115398
Journal of ethnopharmacology 2022 Sep 15;295:115398
Antidepressant effect of Jujuboside A on corticosterone-induced depression in mice.
Li H, Li J, Zhang T, Xie X, Gong J
Biochemical and biophysical research communications 2022 Sep 10;620:56-62
Biochemical and biophysical research communications 2022 Sep 10;620:56-62
Maizediterpene D from the roots of Zea mays L. alleviates hydrogen peroxide induced oxidative stress and improves cell survival by activation of TrkB/IGF-1R crosstalk pathways.
Fan Y, Wu H, Xiong L, Luo F, Li Q, Wang D, Zhong T
Fitoterapia 2022 Nov;163:105314
Fitoterapia 2022 Nov;163:105314
Upregulation of Periostin Through CREB Participates in Myocardial Infarction-induced Myocardial Fibrosis.
Xue K, Chen S, Chai J, Yan W, Zhu X, Dai H, Wang W
Journal of cardiovascular pharmacology 2022 May 1;79(5):687-697
Journal of cardiovascular pharmacology 2022 May 1;79(5):687-697
Inhibition of translocator protein 18 kDa suppressed the progression of glioma via the ELAV-like RNA-binding protein 1/MAPK-activated protein kinase 3 axis.
Wang J, Ren P, Zeng Z, Ma L, Li Y, Zhang H, Guo W
Bioengineered 2022 Mar;13(3):7457-7470
Bioengineered 2022 Mar;13(3):7457-7470
Kinase activity profiling identifies putative downstream targets of cGMP/PKG signaling in inherited retinal neurodegeneration.
Roy A, Tolone A, Hilhorst R, Groten J, Tomar T, Paquet-Durand F
Cell death discovery 2022 Mar 3;8(1):93
Cell death discovery 2022 Mar 3;8(1):93
CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m(6)A-modified CREB1 mRNA.
Yao B, Zhang Q, Yang Z, An F, Nie H, Wang H, Yang C, Sun J, Chen K, Zhou J, Bai B, Gu S, Zhao W, Zhan Q
Molecular cancer 2022 Jun 30;21(1):140
Molecular cancer 2022 Jun 30;21(1):140
A novel phosphodiesterase 9A inhibitor LW33 protects against ischemic stroke through the cGMP/PKG/CREB pathway.
You JY, Liu XW, Bao YX, Shen ZN, Wang Q, He GY, Lu J, Zhang JG, Chen JW, Liu PQ
European journal of pharmacology 2022 Jun 15;925:174987
European journal of pharmacology 2022 Jun 15;925:174987
Metabotropic glutamate receptor 5 upregulation of γ-aminobutyric acid transporter 3 expression ameliorates cognitive impairment after traumatic brain injury in mice.
Xu P, Huang X, Niu W, Yu D, Zhou M, Wang H
Brain research bulletin 2022 Jun 1;183:104-115
Brain research bulletin 2022 Jun 1;183:104-115
The role and mechanism of TLR4-siRNA in the impairment of learning and memory in young mice induced by isoflurane.
Lin L, Chen D, Yu X, Zhong W, Liu Y, Feng Y, Luo H
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2022 Jul;31(7):769-780
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2022 Jul;31(7):769-780
The BDNF-TrkB-CREB Signalling Pathway Is Involved in Bisphenol S-Induced Neurotoxicity in Male Mice by Regulating Methylation.
Li YZ, Wu ZY, Zhu BQ, Wang YX, Kan YQ, Zeng HC
Toxics 2022 Jul 23;10(8)
Toxics 2022 Jul 23;10(8)
Gestational exposure to fluoride impairs cognition in C57 BL/6 J male offspring mice via the p-Creb1-BDNF-TrkB signaling pathway.
Li W, Lu L, Zhu D, Liu J, Shi Y, Zeng H, Yu X, Guo J, Wei B, Cai Y, Sun M
Ecotoxicology and environmental safety 2022 Jul 1;239:113682
Ecotoxicology and environmental safety 2022 Jul 1;239:113682
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
Zhang T, Sun L, Hao Y, Suo C, Shen S, Wei H, Ma W, Zhang P, Wang T, Gu X, Li ST, Chen Z, Yan R, Zhang Y, Cai Y, Zhou R, Jia W, Huang F, Gao P, Zhang H
Nature cancer 2022 Jan;3(1):75-89
Nature cancer 2022 Jan;3(1):75-89
Pan-cancer multi-omics analyses reveal crosstalk between the Hippo and immune signaling pathways in the tumor microenvironment.
Wang C, Zhu T, Zhao Z, Chen B, Chen T, Dong Q, Liu M, Zhuang S, Yang F, Liu Y, Yang M, Gu Y, Liang H
FEBS letters 2022 Feb;596(4):449-464
FEBS letters 2022 Feb;596(4):449-464
WT1 suppresses follicle-stimulating hormone-induced progesterone secretion by regulating ERK1/2 pathway in chicken preovulatory granulosa cells.
Tang S, Li X, Wu X, Gong Y
Gene 2022 Feb 20;812:146097
Gene 2022 Feb 20;812:146097
Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP/PKA signaling pathway in human trophoblastic HTR-8/Svneo cells.
Gu X, Liu H, Luo W, Wang X, Wang H, Li L
Reproductive toxicology (Elmsford, N.Y.) 2022 Dec;114:22-31
Reproductive toxicology (Elmsford, N.Y.) 2022 Dec;114:22-31
Downregulation of IL-8 and IL-10 by the Activation of Ca(2+)-Activated K(+) Channel K(Ca)3.1 in THP-1-Derived M(2) Macrophages.
Ohya S, Matsui M, Kajikuri J, Kito H, Endo K
International journal of molecular sciences 2022 Aug 3;23(15)
International journal of molecular sciences 2022 Aug 3;23(15)
Systematic Survey of the Regulatory Networks of the Long Noncoding RNA BANCR in Cervical Cancer Cells.
Wang B, Wang M, Jia S, Li T, Yang M, Ge F
Journal of proteome research 2022 Apr 1;21(4):1137-1152
Journal of proteome research 2022 Apr 1;21(4):1137-1152
m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis.
Liu Z, Lu J, Fang H, Sheng J, Cui M, Yang Y, Tang B, Zhang X
Frontiers in cell and developmental biology 2021;9:783385
Frontiers in cell and developmental biology 2021;9:783385
CREB Ameliorates Osteoarthritis Progression Through Regulating Chondrocytes Autophagy via the miR-373/METTL3/TFEB Axis.
Zhang H, Li X, Li Y, Yang X, Liao R, Wang H, Yang J
Frontiers in cell and developmental biology 2021;9:778941
Frontiers in cell and developmental biology 2021;9:778941
CREB1 and ATF1 Negatively Regulate Glutathione Biosynthesis Sensitizing Cells to Oxidative Stress.
Zhao L, Xia W, Jiang P
Frontiers in cell and developmental biology 2021;9:698264
Frontiers in cell and developmental biology 2021;9:698264
LncRNA H19 Upregulation Participates in the Response of Glioma Cells to Radiation.
Kuang Y, Bing Z, Jin X, Li Q
BioMed research international 2021;2021:1728352
BioMed research international 2021;2021:1728352
GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic-Pituitary-Adrenal Axis Hyperactivity.
Wang Y, Han J, Zhu J, Zhang M, Ju M, Du Y, Tian Z
Frontiers in neuroscience 2021;15:703044
Frontiers in neuroscience 2021;15:703044
Edaravone Alleviated Propofol-Induced Neurotoxicity in Developing Hippocampus by mBDNF/TrkB/PI3K Pathway.
Yang Y, Yi J, Pan M, Hu B, Duan H
Drug design, development and therapy 2021;15:1409-1422
Drug design, development and therapy 2021;15:1409-1422
A Potential Mechanism Underlying the Therapeutic Effects of Progesterone and Allopregnanolone on Ketamine-Induced Cognitive Deficits.
Cao T, Tang M, Jiang P, Zhang B, Wu X, Chen Q, Zeng C, Li N, Zhang S, Cai H
Frontiers in pharmacology 2021;12:612083
Frontiers in pharmacology 2021;12:612083
An Integrative Pharmacology-Based Strategy to Uncover the Mechanism of Xiong-Pi-Fang in Treating Coronary Heart Disease with Depression.
Zhang L, Zhang Y, Zhu M, Pei L, Deng F, Chen J, Zhang S, Cong Z, Du W, Xiao X
Frontiers in pharmacology 2021;12:590602
Frontiers in pharmacology 2021;12:590602
KDELR2 promotes breast cancer proliferation via HDAC3-mediated cell cycle progression.
Wei H, Ma W, Lu X, Liu H, Lin K, Wang Y, Ye Z, Sun L, Huang Z, Pan T, Zhou Z, Cheng EY, Zhang H, Gao P, Zhong X
Cancer communications (London, England) 2021 Sep;41(9):904-920
Cancer communications (London, England) 2021 Sep;41(9):904-920
Adenylyl cyclase 3 regulates osteocyte mechanotransduction and primary cilium.
Duffy MP, Sup ME, Guo XE
Biochemical and biophysical research communications 2021 Oct 8;573:145-150
Biochemical and biophysical research communications 2021 Oct 8;573:145-150
miR-221/222 suppression induced by activation of the cAMP/PKA/CREB1 pathway is required for cAMP-induced bidirectional differentiation of glioma cells.
Liu Q, Tian R, Yu P, Shu M
FEBS letters 2021 Nov;595(22):2829-2843
FEBS letters 2021 Nov;595(22):2829-2843
Role of the BDNF/TrkB/CREB signaling pathway in the cytotoxicity of bisphenol S in SK-N-SH cells.
He QZ, Zhu BQ, Xu XN, Zeng HC
Journal of biochemical and molecular toxicology 2021 Jun;35(6):1-11
Journal of biochemical and molecular toxicology 2021 Jun;35(6):1-11
Congenital hypothyroidism impairs spine growth of dentate granule cells by downregulation of CaMKIV.
Tang Q, Chen S, Wu H, Song H, Wang Y, Shi J, Wu Y
Cell death discovery 2021 Jun 14;7(1):143
Cell death discovery 2021 Jun 14;7(1):143
A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone.
Fu Y, Xin Z, Ling Z, Xie H, Xiao T, Shen X, Lin J, Xu L, Jiang H
Molecular medicine (Cambridge, Mass.) 2021 Jul 22;27(1):81
Molecular medicine (Cambridge, Mass.) 2021 Jul 22;27(1):81
Uncaria rhynchophylla ameliorates unpredictable chronic mild stress-induced depression in mice via activating 5-HT(1A) receptor: Insights from transcriptomics.
Qiao YL, Zhou JJ, Liang JH, Deng XP, Zhang ZJ, Huang HL, Li S, Dai SF, Liu CQ, Luan ZL, Yu ZL, Sun CP, Ma XC
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153436
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153436
Rapid antidepressant-like effect of Fructus Aurantii depends on cAMP-response element binding protein/Brain-derived neurotrophic facto by mediating synaptic transmission.
Wu L, Zhang T, Chen K, Lu C, Liu XF, Zhou JL, Huang YK, Yan H, Chen Y, Zhang CJ, Li JF, Shi SQ, Ren P, Huang X
Phytotherapy research : PTR 2021 Jan;35(1):404-414
Phytotherapy research : PTR 2021 Jan;35(1):404-414
Glycogen synthase kinase-3β inhibitor SB216763 promotes DNA repair in ischemic retinal neurons.
Zhang J, Lai ZP, Chen P, Ying Y, Zhuang J, Yu KM
Neural regeneration research 2021 Feb;16(2):394-400
Neural regeneration research 2021 Feb;16(2):394-400
mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.
Merle DA, Provenzano F, Jarboui MA, Kilger E, Clark SJ, Deleidi M, Armento A, Ueffing M
Antioxidants (Basel, Switzerland) 2021 Dec 3;10(12)
Antioxidants (Basel, Switzerland) 2021 Dec 3;10(12)
Duzhong Butiansu Prescription Improves Heat Stress-Induced Spermatogenic Dysfunction by Regulating Sperm Formation and Heat Stress Pathway.
Hou Y, Yuan P, Fu Y, Zhang Q, Wei Y, Gao L, Liu L, Wang X, Zheng X, Feng W
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6723204
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6723204
LncRNA BLACAT1/miR-519d-3p/CREB1 Axis Mediates Proliferation, Apoptosis, Migration, Invasion, and Drug-Resistance in Colorectal Cancer Progression.
Chen R, Zhou S, Chen J, Lin S, Ye F, Jiang P
Cancer management and research 2020;12:13137-13148
Cancer management and research 2020;12:13137-13148
Homer1a Undergoes Bimodal Transcriptional Regulation by CREB and the Circadian Clock.
Sato S, Bunney BG, Vawter MP, Bunney WE, Sassone-Corsi P
Neuroscience 2020 May 10;434:161-170
Neuroscience 2020 May 10;434:161-170
Anti-Alzheimer's disease activity of secondary metabolites from Xanthoceras sorbifolia Bunge.
Li W, Lu Q, Li X, Liu H, Sun L, Lu X, Zhao Y, Liu P
Food & function 2020 Mar 1;11(3):2067-2079
Food & function 2020 Mar 1;11(3):2067-2079
Bexarotene Improve Depression-Like Behaviour in Mice by Protecting Against Neuro-inflammation and Synaptic Damage.
Yuan C, Dai C, Li Z, Zheng L, Zhao M, Dong S
Neurochemical research 2020 Jul;45(7):1500-1509
Neurochemical research 2020 Jul;45(7):1500-1509
LncRNA MALAT1 inhibits apoptosis of endometrial stromal cells through miR-126-5p-CREB1 axis by activating PI3K-AKT pathway.
Feng Y, Tan BZ
Molecular and cellular biochemistry 2020 Dec;475(1-2):185-194
Molecular and cellular biochemistry 2020 Dec;475(1-2):185-194
Down-Regulated CUEDC2 Increases GDNF Expression by Stabilizing CREB Through Reducing Its Ubiquitination in Glioma.
Liu XF, Tang CX, Zhang L, Tong SY, Wang Y, Abdulrahman AA, Ji GQ, Gao Y, Gao DS, Zhang BL
Neurochemical research 2020 Dec;45(12):2915-2925
Neurochemical research 2020 Dec;45(12):2915-2925
Saikosaponin-d impedes hippocampal neurogenesis and causes cognitive deficits by inhibiting the survival of neural stem/progenitor cells via neurotrophin receptor signaling in mice.
Qin T, Yuan Z, Yu J, Fu X, Deng X, Fu Q, Ma Z, Ma S
Clinical and translational medicine 2020 Dec;10(8):e243
Clinical and translational medicine 2020 Dec;10(8):e243
PTEN participates in airway remodeling of asthma by regulating CD38/Ca(2+)/CREB signaling.
Wu Y, Lu Y, Zou F, Fan X, Li X, Zhang H, Chen H, Sun X, Liu Y
Aging 2020 Aug 27;12(16):16326-16340
Aging 2020 Aug 27;12(16):16326-16340
The potential role of Krüppel-like factor 13 (Aj-klf13) in the intestine regeneration of sea cucumber Apostichopus japonicus.
Chen L, Yao F, Qin Y, Shao Y, Fang L, Yu X, Wang S, Hou L
Gene 2020 Apr 20;735:144407
Gene 2020 Apr 20;735:144407
MicroRNA-23a-3p Inhibits Mucosal Melanoma Growth and Progression through Targeting Adenylate Cyclase 1 and Attenuating cAMP and MAPK Pathways.
Ma M, Dai J, Tang H, Xu T, Yu S, Si L, Cui C, Sheng X, Chi Z, Mao L, Wu X, Yang L, Yu H, Li S, Lian B, Tang B, Wang X, Yan X, Bai X, Zhou L, Kong Y, Guo J
Theranostics 2019;9(4):945-960
Theranostics 2019;9(4):945-960
CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress.
Li Q, Wang Y, Wu S, Zhou Z, Ding X, Shi R, Thorne RF, Zhang XD, Hu W, Wu M
Cell metabolism 2019 Jul 2;30(1):157-173.e7
Cell metabolism 2019 Jul 2;30(1):157-173.e7
ZNF436 promotes tumor cell proliferation through transcriptional activation of BCL10 in glioma.
Shang Y, Li Y, Zhang Y, Wang J
Biochemical and biophysical research communications 2019 Aug 6;515(4):572-578
Biochemical and biophysical research communications 2019 Aug 6;515(4):572-578
Metformin Modulates High Glucose-Incubated Human Umbilical Vein Endothelial Cells Proliferation and Apoptosis Through AMPK/CREB/BDNF Pathway.
Han X, Wang B, Sun Y, Huang J, Wang X, Ma W, Zhu Y, Xu R, Jin H, Liu N
Frontiers in pharmacology 2018;9:1266
Frontiers in pharmacology 2018;9:1266
Neurotoxicity, behavioral changes and gene-expression profile of mice exposed to SnS(2) nanoflowers.
Bai D, Li Q, Wang J, Zhao J, Deng X, Yuan L, Wu P
Toxicology research 2018 Nov 1;7(6):1267-1279
Toxicology research 2018 Nov 1;7(6):1267-1279
Calretinin Participates in Regulating Steroidogenesis by PLC-Ca(2+)-PKC Pathway in Leydig Cells.
Xu W, Zhu Q, Liu S, Dai X, Zhang B, Gao C, Gao L, Liu J, Cui Y
Scientific reports 2018 May 9;8(1):7403
Scientific reports 2018 May 9;8(1):7403
Analysis of the oncogene BRAF mutation and the correlation of the expression of wild-type BRAF and CREB1 in endometriosis.
Lv X, Wang D, Ma Y, Long Z
International journal of molecular medicine 2018 Mar;41(3):1349-1356
International journal of molecular medicine 2018 Mar;41(3):1349-1356
Effects of fluoride on synapse morphology and myelin damage in mouse hippocampus.
Niu R, Chen H, Manthari RK, Sun Z, Wang J, Zhang J, Wang J
Chemosphere 2018 Mar;194:628-633
Chemosphere 2018 Mar;194:628-633
Inhibition of Acid Sensing Ion Channel 3 Aggravates Seizures by Regulating NMDAR Function.
Cao Q, Xiao ZM, Wang X, Weng C, Ding M, Zhu F, Lu ZN
Neurochemical research 2018 Jun;43(6):1227-1241
Neurochemical research 2018 Jun;43(6):1227-1241
A CREB1/miR-433 reciprocal feedback loop modulates proliferation and metastasis in colorectal cancer.
Yan L, You WQ, Sheng NQ, Gong JF, Hu LD, Tan GW, Chen HQ, Wang ZG
Aging 2018 Dec 6;10(12):3774-3793
Aging 2018 Dec 6;10(12):3774-3793
Icariin Attenuates Synaptic and Cognitive Deficits in an Aβ(1-42)-Induced Rat Model of Alzheimer's Disease.
Sheng C, Xu P, Zhou K, Deng D, Zhang C, Wang Z
BioMed research international 2017;2017:7464872
BioMed research international 2017;2017:7464872
Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol-induced steatosis.
Avila DV, Barker DF, Zhang J, McClain CJ, Barve S, Gobejishvili L
The Journal of pathology 2016 Sep;240(1):96-107
The Journal of pathology 2016 Sep;240(1):96-107
Epicatechin Plus Treadmill Exercise are Neuroprotective Against Moderate-stage Amyloid Precursor Protein/Presenilin 1 Mice.
Zhang Z, Wu H, Huang H
Pharmacognosy magazine 2016 May;12(Suppl 2):S139-46
Pharmacognosy magazine 2016 May;12(Suppl 2):S139-46
LncRNA-UCA1 enhances cell proliferation and 5-fluorouracil resistance in colorectal cancer by inhibiting miR-204-5p.
Bian Z, Jin L, Zhang J, Yin Y, Quan C, Hu Y, Feng Y, Liu H, Fei B, Mao Y, Zhou L, Qi X, Huang S, Hua D, Xing C, Huang Z
Scientific reports 2016 Apr 5;6:23892
Scientific reports 2016 Apr 5;6:23892
BDNF-dependent recycling facilitates TrkB translocation to postsynaptic density during LTP via a Rab11-dependent pathway.
Huang SH, Wang J, Sui WH, Chen B, Zhang XY, Yan J, Geng Z, Chen ZY
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 May 22;33(21):9214-30
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 May 22;33(21):9214-30
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CREB1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CREB1. This antibody recognizes human, mouse, rat, monkey antigen. The CREB1 antibody has been validated for the following applications: ELISA, IP, WB, IF, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HEK-293 cells using 12208-1-AP( CREB1 Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-CREB1 (IP:12208-1-AP, 3ug; Detection:12208-1-AP 1:600) with HEK-293 cells lysate 2000ug.
- Sample type
- cell line
