Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- PAB12522 - Provider product page

- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12522, RRID:AB_10549270
- Product name
- CREB1 (phospho S121) polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of CREB1.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Identification of carboxyl-terminal MCM3 phosphorylation sites using polyreactive phosphospecific antibodies.
Coregulated ataxia telangiectasia-mutated and casein kinase sites modulate cAMP-response element-binding protein-coactivator interactions in response to DNA damage.
DNA replication stress-induced phosphorylation of cyclic AMP response element-binding protein mediated by ATM.
Ataxia-telangiectasia-mutated (ATM) is a T-antigen kinase that controls SV40 viral replication in vivo.
Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress.
Shi Y, Dodson GE, Mukhopadhyay PS, Shanware NP, Trinh AT, Tibbetts RS
The Journal of biological chemistry 2007 Mar 23;282(12):9236-43
The Journal of biological chemistry 2007 Mar 23;282(12):9236-43
Coregulated ataxia telangiectasia-mutated and casein kinase sites modulate cAMP-response element-binding protein-coactivator interactions in response to DNA damage.
Shanware NP, Trinh AT, Williams LM, Tibbetts RS
The Journal of biological chemistry 2007 Mar 2;282(9):6283-91
The Journal of biological chemistry 2007 Mar 2;282(9):6283-91
DNA replication stress-induced phosphorylation of cyclic AMP response element-binding protein mediated by ATM.
Dodson GE, Tibbetts RS
The Journal of biological chemistry 2006 Jan 20;281(3):1692-7
The Journal of biological chemistry 2006 Jan 20;281(3):1692-7
Ataxia-telangiectasia-mutated (ATM) is a T-antigen kinase that controls SV40 viral replication in vivo.
Shi Y, Dodson GE, Shaikh S, Rundell K, Tibbetts RS
The Journal of biological chemistry 2005 Dec 2;280(48):40195-200
The Journal of biological chemistry 2005 Dec 2;280(48):40195-200
Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress.
Shi Y, Venkataraman SL, Dodson GE, Mabb AM, LeBlanc S, Tibbetts RS
Proceedings of the National Academy of Sciences of the United States of America 2004 Apr 20;101(16):5898-903
Proceedings of the National Academy of Sciences of the United States of America 2004 Apr 20;101(16):5898-903
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
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- Experimental details
- Western blot analysis of CREB1 (phospho S121) in human HEK 293T cells.Top panel : probed with CREB1 (phospho S121) polyclonal antibody (Cat # PAB12522). Bottom panel : probed with CREB antibody. Lanes 2 and 4 treated with lambda phosphatase, lanes 3 and 4 treated with 0.2mM H202.