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- Antibody Data
- Antigen structure
- References [7]
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- Product number
- ABIN116949 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-CAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody
- Antibody type
- Polyclonal
- Antigen
- CREB phospho peptide corresponding to a region of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
- Description
- Affinity Purified
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antigen sequence
Q-K-R-R-E-I-L-S-R-R-P-pS-Y-R-K-I-L-
N-D-L-S-S-D-A-P corresponding to aa
122-147- Epitope
- pSer133
- Vial size
- 0.1 mL
- Concentration
- 0.064 mg/mL (by UV absorbance at 280 nm)
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells.
Distinct cAMP response element-binding protein (CREB) domains stimulate different steps in a concerted mechanism of transcription activation.
CREB regulates MHC class II expression in a CIITA-dependent manner.
Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB.
Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP.
Both the basic region and the 'leucine zipper' domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation.
Cyclic-AMP-responsive transcriptional activation of CREB-327 involves interdependent phosphorylated subdomains.
Arthur JS, Cohen P
FEBS letters 2000 Sep 29;482(1-2):44-8
FEBS letters 2000 Sep 29;482(1-2):44-8
Distinct cAMP response element-binding protein (CREB) domains stimulate different steps in a concerted mechanism of transcription activation.
Kim J, Lu J, Quinn PG
Proceedings of the National Academy of Sciences of the United States of America 2000 Oct 10;97(21):11292-6
Proceedings of the National Academy of Sciences of the United States of America 2000 Oct 10;97(21):11292-6
CREB regulates MHC class II expression in a CIITA-dependent manner.
Moreno CS, Beresford GW, Louis-Plence P, Morris AC, Boss JM
Immunity 1999 Feb;10(2):143-51
Immunity 1999 Feb;10(2):143-51
Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB.
Barton K, Muthusamy N, Chanyangam M, Fischer C, Clendenin C, Leiden JM
Nature 1996 Jan 4;379(6560):81-5
Nature 1996 Jan 4;379(6560):81-5
Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP.
Kwok RP, Laurance ME, Lundblad JR, Goldman PS, Shih H, Connor LM, Marriott SJ, Goodman RH
Nature 1996 Apr 18;380(6575):642-6
Nature 1996 Apr 18;380(6575):642-6
Both the basic region and the 'leucine zipper' domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation.
Dwarki VJ, Montminy M, Verma IM
The EMBO journal 1990 Jan;9(1):225-32
The EMBO journal 1990 Jan;9(1):225-32
Cyclic-AMP-responsive transcriptional activation of CREB-327 involves interdependent phosphorylated subdomains.
Lee CQ, Yun YD, Hoeffler JP, Habener JF
The EMBO journal 1990 Dec;9(13):4455-65
The EMBO journal 1990 Dec;9(13):4455-65
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