Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- NB100-410 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-410, RRID:AB_10002113
- Product name
- Rabbit Polyclonal CREB Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 0.3 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references A Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour Development.
Hypoxia-mediated alterations and their role in the HER-2/neuregulated CREB status and localization.
Severe reaction to radiotherapy for breast cancer as the presenting feature of ataxia telangiectasia.
Identification of carboxyl-terminal MCM3 phosphorylation sites using polyreactive phosphospecific antibodies.
Coregulated ataxia telangiectasia-mutated and casein kinase sites modulate cAMP-response element-binding protein-coactivator interactions in response to DNA damage.
DNA replication stress-induced phosphorylation of cyclic AMP response element-binding protein mediated by ATM.
Ataxia-telangiectasia-mutated (ATM) is a T-antigen kinase that controls SV40 viral replication in vivo.
Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress.
Byrd PJ, Stewart GS, Smith A, Eaton C, Taylor AJ, Guy C, Eringyte I, Fooks P, Last JI, Horsley R, Oliver AW, Janic D, Dokmanovic L, Stankovic T, Taylor AM
PLoS genetics 2016 Mar;12(3):e1005945
PLoS genetics 2016 Mar;12(3):e1005945
Hypoxia-mediated alterations and their role in the HER-2/neuregulated CREB status and localization.
Steven A, Leisz S, Sychra K, Hiebl B, Wickenhauser C, Mougiakakos D, Kiessling R, Denkert C, Seliger B
Oncotarget 2016 Aug 9;7(32):52061-52084
Oncotarget 2016 Aug 9;7(32):52061-52084
Severe reaction to radiotherapy for breast cancer as the presenting feature of ataxia telangiectasia.
Byrd PJ, Srinivasan V, Last JI, Smith A, Biggs P, Carney EF, Exley A, Abson C, Stewart GS, Izatt L, Taylor AM
British journal of cancer 2012 Jan 17;106(2):262-8
British journal of cancer 2012 Jan 17;106(2):262-8
Identification of carboxyl-terminal MCM3 phosphorylation sites using polyreactive phosphospecific antibodies.
Shi Y, Dodson GE, Mukhopadhyay PS, Shanware NP, Trinh AT, Tibbetts RS
The Journal of biological chemistry 2007 Mar 23;282(12):9236-43
The Journal of biological chemistry 2007 Mar 23;282(12):9236-43
Coregulated ataxia telangiectasia-mutated and casein kinase sites modulate cAMP-response element-binding protein-coactivator interactions in response to DNA damage.
Shanware NP, Trinh AT, Williams LM, Tibbetts RS
The Journal of biological chemistry 2007 Mar 2;282(9):6283-91
The Journal of biological chemistry 2007 Mar 2;282(9):6283-91
DNA replication stress-induced phosphorylation of cyclic AMP response element-binding protein mediated by ATM.
Dodson GE, Tibbetts RS
The Journal of biological chemistry 2006 Jan 20;281(3):1692-7
The Journal of biological chemistry 2006 Jan 20;281(3):1692-7
Ataxia-telangiectasia-mutated (ATM) is a T-antigen kinase that controls SV40 viral replication in vivo.
Shi Y, Dodson GE, Shaikh S, Rundell K, Tibbetts RS
The Journal of biological chemistry 2005 Dec 2;280(48):40195-200
The Journal of biological chemistry 2005 Dec 2;280(48):40195-200
Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress.
Shi Y, Venkataraman SL, Dodson GE, Mabb AM, LeBlanc S, Tibbetts RS
Proceedings of the National Academy of Sciences of the United States of America 2004 Apr 20;101(16):5898-903
Proceedings of the National Academy of Sciences of the United States of America 2004 Apr 20;101(16):5898-903
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CREB [p Ser121] Antibody [NB100-410] - Detection of phospho-CREB in human HEK 293T cells. Top panel: probed with NB 100-410. Bottom panel: probed with CREB antibody. Lanes 2 and 4 treated with lambda phosphatase, lanes 3 and 4 treated with 0.2 mM H2O2.