21050-1-AP
antibody from Proteintech Group
Targeting: EPCAM
17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1
Antibody data
- Antibody Data
- Antigen structure
- References [67]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
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- Product number
- 21050-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21050-1-AP, RRID:AB_10693684
- Product name
- EPCAM antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EPCAM antibody (Cat. #21050-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Detection of SARS-CoV-2 virus in middle ear effusions and its association with otitis media with effusion.
ZNF217-activated Notch signaling mediates sulforaphane-suppressed stem cell properties in colorectal cancer.
Amelioration of NAFLD by sleeve gastrectomy-triggered hepatocyte regeneration in mice - experimental research.
A novel causative role of imbalanced kynurenine pathway in ulcerative colitis: Upregulation of KMO and KYNU promotes intestinal inflammation.
Calcitriol promotes M2 polarization of tumor-associated macrophages in 4T1 mouse mammary gland cancer via the induction of proinflammatory cytokines.
Arctigenin promotes mucosal healing in ulcerative colitis through facilitating focal adhesion assembly and colonic epithelial cell migration via targeting focal adhesion kinase.
Icariin Regulates EMT and Stem Cell-Like Character in Breast Cancer through Modulating lncRNA NEAT1/TGFβ/SMAD2 Signaling Pathway.
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers.
Bacterial indole-3-lactic acid affects epithelium-macrophage crosstalk to regulate intestinal homeostasis.
Nickel-Doped Microfluidic Chip for Rapid and Efficient Immunomagnetic Separation and Detection of Breast Cancer Cell-Derived Exosomes.
m(6)A methylation reader IGF2BP2 activates endothelial cells to promote angiogenesis and metastasis of lung adenocarcinoma.
Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
CD166-specific CAR-T cells potently target colorectal cancer cells.
Budget-Friendly Generation, Biochemical Analyses, and Lentiviral Transduction of Patient-Derived Colon Organoids.
PUFAs add fuel to Crohn's disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation.
Multivalent DNA Flowers for High-Performance Isolation, Detection, and Release of Tumor-Derived Extracellular Vesicles.
Loss of SPTBN1 Suppresses Autophagy Via SETD7-mediated YAP Methylation in Hepatocellular Carcinoma Initiation and Development.
Blockade of phosphotyrosine pathways suggesting SH2 superbinder as a novel therapy for pulmonary fibrosis.
Fetal Lung-Derived Exosomes in Term Labor Amniotic Fluid Induce Amniotic Membrane Senescence.
ΔNp63α mediates sulforaphane suppressed colorectal cancer stem cell properties through transcriptional regulation of Nanog/Oct4/Sox2.
Single-cell transcriptomic analysis highlights origin and pathological process of human endometrioid endometrial carcinoma.
Treating intrauterine adhesion using conditionally reprogrammed physiological endometrial epithelial cells.
N-methyl-D-aspartate receptor blockers attenuate bleomycin-induced pulmonary fibrosis by inhibiting endogenous mesenchymal stem cells senescence.
Deglycosylated EpCAM regulates proliferation by enhancing autophagy of breast cancer cells via PI3K/Akt/mTOR pathway.
Mitigation of portal fibrosis and cholestatic liver disease in ANKS6-deficient livers by macrophage depletion.
Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.
Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability.
The Ginsenoside Compound K Suppresses Stem-Cell-like Properties and Colorectal Cancer Metastasis by Targeting Hypoxia-Driven Nur77-Akt Feed-Forward Signaling.
Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer.
EMT status of circulating breast cancer cells and impact of fluidic shear stress.
Suppression of rhomboid domain-containing 1 produces anticancer effects in pancreatic adenocarcinoma through affection of the AKT/GSK-3β/β-catenin pathway.
CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma.
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Sirt1 Promotes the Restoration of Hepatic Progenitor Cell (HPC)-Mediated Liver Fatty Injury in NAFLD Through Activating the Wnt/β-Catenin Signal Pathway.
Targeting Wnt Signaling in the Tumor Immune Microenvironment to Enhancing EpCAM CAR T-Cell therapy.
Pharmacological targeting PTK6 inhibits the JAK2/STAT3 sustained stemness and reverses chemoresistance of colorectal cancer.
Rolling Circle Amplification-Assisted Flow Cytometry Approach for Simultaneous Profiling of Exosomal Surface Proteins.
The stemness of hepatocytes is maintained by high levels of lipopolysaccharide via YAP1 activation.
EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice.
A stress-induced tyrosine-tRNA depletion response mediates codon-based translational repression and growth suppression.
Expression of Cancer Stem Cell Markers EpCAM and CD90 Is Correlated with Anti- and Pro-Oncogenic EphA2 Signaling in Hepatocellular Carcinoma.
Near-infrared-driven fluorescent nanomotors for detection of circulating tumor cells in whole blood.
Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma.
Cross-talk between the gut microbiota and monocyte-like macrophages mediates an inflammatory response to promote colitis-associated tumourigenesis.
MiR-7 reduces the BCSC subset by inhibiting XIST to modulate the miR-92b/Slug/ESA axis and inhibit tumor growth.
Hedgehog signaling promotes sorafenib resistance in hepatocellular carcinoma patient-derived organoids.
Tumor-cell detection, labeling and phenotyping with an electron-doped bifunctional signal-amplifier.
miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis.
In Vivo Study on the Effects of Xiaoaiping on the Stemness of Hepatocellular Carcinoma Cells.
Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine.
High CCL7 expression is associated with migration, invasion and bone metastasis of non-small cell lung cancer cells.
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
Deglycosylation of epithelial cell adhesion molecule affects epithelial to mesenchymal transition in breast cancer cells.
Curcumin attenuates resistance to irinotecan via induction of apoptosis of cancer stem cells in chemoresistant colon cancer cells.
A simple microdevice for single cell capture, array, release, and fast staining using oscillatory method.
Tropism of liver epithelial cells toward hepatocellular carcinoma in vitro and in vivo with altering gene expression of cancer stem cells.
EpCAM and COX‑2 expression are positively correlated in human breast cancer.
Bufalin suppresses cancer stem-like cells in gemcitabine-resistant pancreatic cancer cells via Hedgehog signaling.
Liver epithelial cells inhibit proliferation and invasiveness of hepatoma cells.
EpCAM expression in breast cancer cells is associated with enhanced bone metastasis formation.
High LIN28A Expressing Ovarian Cancer Cells Secrete Exosomes That Induce Invasion and Migration in HEK293 Cells.
ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis.
Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Recovery of mature hepatocytic phenotype following bile ductular transdifferentiation of rat hepatocytes in vitro.
Fu X, Wang Z, Chen B, Sun H, Lyu J, Shao J, Lu X, Xu J, Yang J, Chi F, Huang Y, Ren D
Journal of medical virology 2024 Mar;96(3):e29545
Journal of medical virology 2024 Mar;96(3):e29545
ZNF217-activated Notch signaling mediates sulforaphane-suppressed stem cell properties in colorectal cancer.
Wang M, Tang L, Chen S, Wang L, Wu J, Zhong C, Li Y, Chen Y
The Journal of nutritional biochemistry 2024 Mar;125:109551
The Journal of nutritional biochemistry 2024 Mar;125:109551
Amelioration of NAFLD by sleeve gastrectomy-triggered hepatocyte regeneration in mice - experimental research.
Yu T, Ma X, Cheng Y, Wang Z, Zhang G, Ding H, Yin J, Wang Y, Hu S
International journal of surgery (London, England) 2024 Jun 1;110(6):3307-3325
International journal of surgery (London, England) 2024 Jun 1;110(6):3307-3325
A novel causative role of imbalanced kynurenine pathway in ulcerative colitis: Upregulation of KMO and KYNU promotes intestinal inflammation.
Shi Y, Luo S, Zhai J, Chen Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166929
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166929
Calcitriol promotes M2 polarization of tumor-associated macrophages in 4T1 mouse mammary gland cancer via the induction of proinflammatory cytokines.
Stachowicz-Suhs M, Łabędź N, Anisiewicz A, Banach J, Kłopotowska D, Milczarek M, Piotrowska A, Dzięgiel P, Maciejczyk A, Matkowski R, Wietrzyk J
Scientific reports 2024 Feb 15;14(1):3778
Scientific reports 2024 Feb 15;14(1):3778
Arctigenin promotes mucosal healing in ulcerative colitis through facilitating focal adhesion assembly and colonic epithelial cell migration via targeting focal adhesion kinase.
Guo Y, Liu X, Tao Y, Zhu Y, Zhang J, Yu X, Guo P, Liu S, Wei Z, Dai Y, Xia Y
International immunopharmacology 2024 Feb 15;128:111552
International immunopharmacology 2024 Feb 15;128:111552
Icariin Regulates EMT and Stem Cell-Like Character in Breast Cancer through Modulating lncRNA NEAT1/TGFβ/SMAD2 Signaling Pathway.
Song B, Wei F, Peng J, Wei X, Liu M, Nie Z, Ma Y, Peng T
Biological & pharmaceutical bulletin 2024 Feb 10;47(2):399-410
Biological & pharmaceutical bulletin 2024 Feb 10;47(2):399-410
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Jiang Y, Wang Y, Chen G, Sun F, Wu Q, Huang Q, Zeng D, Qiu W, Wang J, Yao Z, Liang B, Li S, Wu J, Huang N, Wang Y, Chen J, Zhai X, Huang L, Xu B, Yamamoto M, Tsukamoto T, Nomura S, Liao W, Shi M
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers.
Zhou DD, Zhai XT, Zhang LW, Xie ZH, Wang Y, Zhen YS, Gao RJ, Miao QF
NPJ precision oncology 2024 Apr 23;8(1):94
NPJ precision oncology 2024 Apr 23;8(1):94
Bacterial indole-3-lactic acid affects epithelium-macrophage crosstalk to regulate intestinal homeostasis.
Yu K, Li Q, Sun X, Peng X, Tang Q, Chu H, Zhou L, Wang B, Zhou Z, Deng X, Yang J, Lv J, Liu R, Miao C, Zhao W, Yao Z, Wang Q
Proceedings of the National Academy of Sciences of the United States of America 2023 Nov 7;120(45):e2309032120
Proceedings of the National Academy of Sciences of the United States of America 2023 Nov 7;120(45):e2309032120
Nickel-Doped Microfluidic Chip for Rapid and Efficient Immunomagnetic Separation and Detection of Breast Cancer Cell-Derived Exosomes.
Fang H, Liu M, Jiang W
Applied biochemistry and biotechnology 2023 May;195(5):3109-3121
Applied biochemistry and biotechnology 2023 May;195(5):3109-3121
m(6)A methylation reader IGF2BP2 activates endothelial cells to promote angiogenesis and metastasis of lung adenocarcinoma.
Fang H, Sun Q, Zhou J, Zhang H, Song Q, Zhang H, Yu G, Guo Y, Huang C, Mou Y, Jia C, Song Y, Liu A, Song K, Lu C, Tian R, Wei S, Yang D, Chen Y, Li T, Wang K, Yu Y, Lv Y, Mo K, Sun P, Yu X, Song X
Molecular cancer 2023 Jun 23;22(1):99
Molecular cancer 2023 Jun 23;22(1):99
Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
Lu Y, Tang K, Wang S, Tian Z, Fan Y, Li B, Wang M, Zhao J, Xie J
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:54-65
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:54-65
CD166-specific CAR-T cells potently target colorectal cancer cells.
He S, Li S, Guo J, Zeng X, Liang D, Zhu Y, Li Y, Yang D, Zhao X
Translational oncology 2023 Jan;27:101575
Translational oncology 2023 Jan;27:101575
Budget-Friendly Generation, Biochemical Analyses, and Lentiviral Transduction of Patient-Derived Colon Organoids.
Rigaux E, Chen JW, George F, Lemaire J, Bertrand C, Faugeras L, Fattaccioli A, Gilliaux Q, D'Hondt L, Michiels C, Renard HF, Zanin N
Current protocols 2023 Dec;3(12):e943
Current protocols 2023 Dec;3(12):e943
PUFAs add fuel to Crohn's disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation.
Wen W, Xu Y, Qian W, Huang L, Gong J, Li Y, Zhu W, Guo Z
Gut microbes 2023 Dec;15(2):2265578
Gut microbes 2023 Dec;15(2):2265578
Multivalent DNA Flowers for High-Performance Isolation, Detection, and Release of Tumor-Derived Extracellular Vesicles.
Ren Y, Ge K, Lu W, Xie X, Lu Y, Wang M, Yao B
ACS applied materials & interfaces 2023 Dec 6;15(48):55358-55368
ACS applied materials & interfaces 2023 Dec 6;15(48):55358-55368
Loss of SPTBN1 Suppresses Autophagy Via SETD7-mediated YAP Methylation in Hepatocellular Carcinoma Initiation and Development.
Chen S, Wu H, Wang Z, Jia M, Guo J, Jin J, Li X, Meng D, Lin L, He AR, Zhou P, Zhi X
Cellular and molecular gastroenterology and hepatology 2022;13(3):949-973.e7
Cellular and molecular gastroenterology and hepatology 2022;13(3):949-973.e7
Blockade of phosphotyrosine pathways suggesting SH2 superbinder as a novel therapy for pulmonary fibrosis.
Wang M, Liu AD, Niu Q, Feng X, Zheng YY, Chen SJ, Xu H, Li Q, Hou GQ, Bi XY, Lu YZ, Cheng PP, Liang LM, Jiang YH, Zhao LQ, Liu F, Song LJ, Zhou LL, Xiao LY, Chen F, Li SS, Ma WL, Cao X, Ye H
Theranostics 2022;12(10):4513-4535
Theranostics 2022;12(10):4513-4535
Fetal Lung-Derived Exosomes in Term Labor Amniotic Fluid Induce Amniotic Membrane Senescence.
Wan S, Chen P, Gu M, Liu J, Zhou Q, Zhang F, Lu Y, Li L, Wang X
Frontiers in cell and developmental biology 2022;10:889861
Frontiers in cell and developmental biology 2022;10:889861
ΔNp63α mediates sulforaphane suppressed colorectal cancer stem cell properties through transcriptional regulation of Nanog/Oct4/Sox2.
Chen Y, Wang MH, Wu JY, Zhu JY, Xie CF, Li XT, Wu JS, Geng SS, Li YD, Han HY, Zhong CY
The Journal of nutritional biochemistry 2022 Sep;107:109067
The Journal of nutritional biochemistry 2022 Sep;107:109067
Single-cell transcriptomic analysis highlights origin and pathological process of human endometrioid endometrial carcinoma.
Ren X, Liang J, Zhang Y, Jiang N, Xu Y, Qiu M, Wang Y, Zhao B, Chen X
Nature communications 2022 Oct 22;13(1):6300
Nature communications 2022 Oct 22;13(1):6300
Treating intrauterine adhesion using conditionally reprogrammed physiological endometrial epithelial cells.
Xia S, Wu M, Zhou X, Zhang X, Ye L, Zhang K, Kang Y, Liu J, Zhang Y, Wu W, Dong D, Chen H, Li H
Stem cell research & therapy 2022 May 3;13(1):178
Stem cell research & therapy 2022 May 3;13(1):178
N-methyl-D-aspartate receptor blockers attenuate bleomycin-induced pulmonary fibrosis by inhibiting endogenous mesenchymal stem cells senescence.
Huang P, Zhou Y, Li XH, Zhang YN, Cheng HP, Fu JF, Liu W, Yue S, Luo ZQ
Annals of translational medicine 2022 Jun;10(11):642
Annals of translational medicine 2022 Jun;10(11):642
Deglycosylated EpCAM regulates proliferation by enhancing autophagy of breast cancer cells via PI3K/Akt/mTOR pathway.
Yang L, Wang Q, Zhao Q, Yang F, Liu T, Huang X, Yan Q, Yang X
Aging 2022 Jan 4;14(1):316-329
Aging 2022 Jan 4;14(1):316-329
Mitigation of portal fibrosis and cholestatic liver disease in ANKS6-deficient livers by macrophage depletion.
Airik M, McCourt B, Ozturk TT, Huynh AB, Zhang X, Tometich JT, Topaloglu R, Ozen H, Orhan D, Nejak-Bowen K, Monga SP, Hand TW, Ozaltin F, Airik R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22157
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22157
Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway.
Tang W, Xue J, Luo L, Wang Y, Cai X, Liu Y, Huang D, Wang X, He T, Lu D, Yang F
Molecular medicine reports 2022 Feb;25(2)
Molecular medicine reports 2022 Feb;25(2)
Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability.
Wu Q, Huang Q, Jiang Y, Sun F, Liang B, Wang J, Hu X, Sun M, Ma Z, Shi Y, Liang Y, Tan Y, Zeng D, Yao F, Xu X, Yao Z, Li S, Rong X, Huang N, Sun L, Liao W, Shi M
Cancer immunology research 2022 Feb;10(2):182-199
Cancer immunology research 2022 Feb;10(2):182-199
The Ginsenoside Compound K Suppresses Stem-Cell-like Properties and Colorectal Cancer Metastasis by Targeting Hypoxia-Driven Nur77-Akt Feed-Forward Signaling.
Zhang M, Shi Z, Zhang S, Li X, To SKY, Peng Y, Liu J, Chen S, Hu H, Wong AST, Zeng JZ
Cancers 2022 Dec 20;15(1)
Cancers 2022 Dec 20;15(1)
Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer.
Yang XY, Zhang JG, Zhou QM, Yu JN, Lu YF, Wang XJ, Zhou JP, Ding XF, Du YZ, Yu RS
Journal of nanobiotechnology 2022 Dec 10;20(1):524
Journal of nanobiotechnology 2022 Dec 10;20(1):524
EMT status of circulating breast cancer cells and impact of fluidic shear stress.
Jin Y, Cai W, Zhao C, Yang F, Yang C, Zhang X, Zhou Q, Zhao W, Zhang C, Zhang F, Wang M, Li M
Experimental cell research 2022 Dec 1;421(1):113385
Experimental cell research 2022 Dec 1;421(1):113385
Suppression of rhomboid domain-containing 1 produces anticancer effects in pancreatic adenocarcinoma through affection of the AKT/GSK-3β/β-catenin pathway.
Jiang J, Cheng Y, Dai S, Zou B, Guo X
Environmental toxicology 2022 Aug;37(8):1944-1956
Environmental toxicology 2022 Aug;37(8):1944-1956
CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma.
Wang J, Zhou Y, Zhang D, Zhao W, Lu Y, Liu C, Lin W, Zhang Y, Chen K, Wang H, Zhao L
The EMBO journal 2022 Aug 1;41(15):e110218
The EMBO journal 2022 Aug 1;41(15):e110218
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Cao W, Li Y, Sun H, Yang C, Zhu J, Xie C, Li X, Wu J, Geng S, Wang L, Sun L, Geng G, Han H, Zhong C
Frontiers in cell and developmental biology 2021;9:679806
Frontiers in cell and developmental biology 2021;9:679806
Sirt1 Promotes the Restoration of Hepatic Progenitor Cell (HPC)-Mediated Liver Fatty Injury in NAFLD Through Activating the Wnt/β-Catenin Signal Pathway.
Li Q, Gong Y, Wang Y, Liu B, Chu Y, Gui S, Zheng Y, Chen X
Frontiers in nutrition 2021;8:791861
Frontiers in nutrition 2021;8:791861
Targeting Wnt Signaling in the Tumor Immune Microenvironment to Enhancing EpCAM CAR T-Cell therapy.
Li W, Zhou Y, Wu Z, Shi Y, Tian E, Zhu Y, Wang T, Dou W, Meng X, Chen M, Zhai B, Zhu D
Frontiers in pharmacology 2021;12:724306
Frontiers in pharmacology 2021;12:724306
Pharmacological targeting PTK6 inhibits the JAK2/STAT3 sustained stemness and reverses chemoresistance of colorectal cancer.
Liu C, Pan Z, Chen Q, Chen Z, Liu W, Wu L, Jiang M, Lin W, Zhang Y, Lin W, Zhou R, Zhao L
Journal of experimental & clinical cancer research : CR 2021 Sep 22;40(1):297
Journal of experimental & clinical cancer research : CR 2021 Sep 22;40(1):297
Rolling Circle Amplification-Assisted Flow Cytometry Approach for Simultaneous Profiling of Exosomal Surface Proteins.
Gao X, Teng X, Dai Y, Li J
ACS sensors 2021 Oct 22;6(10):3611-3620
ACS sensors 2021 Oct 22;6(10):3611-3620
The stemness of hepatocytes is maintained by high levels of lipopolysaccharide via YAP1 activation.
Shao C, Yang X, Jing Y, Hou X, Huang Y, Zong C, Gao L, Liu W, Jiang J, Ye F, Shi J, Zhao Q, Li R, Zhang X, Wei L
Stem cell research & therapy 2021 Jun 10;12(1):342
Stem cell research & therapy 2021 Jun 10;12(1):342
EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice.
Jia Z, Bao K, Wei P, Yu X, Zhang Y, Wang X, Wang X, Yao L, Li L, Wu P, Yuan W, Wang S, Zheng J, Hua Y, Hong M
Mucosal immunology 2021 Jan;14(1):125-134
Mucosal immunology 2021 Jan;14(1):125-134
A stress-induced tyrosine-tRNA depletion response mediates codon-based translational repression and growth suppression.
Huh D, Passarelli MC, Gao J, Dusmatova SN, Goin C, Fish L, Pinzaru AM, Molina H, Ren Z, McMillan EA, Asgharian H, Goodarzi H, Tavazoie SF
The EMBO journal 2021 Jan 15;40(2):e106696
The EMBO journal 2021 Jan 15;40(2):e106696
Expression of Cancer Stem Cell Markers EpCAM and CD90 Is Correlated with Anti- and Pro-Oncogenic EphA2 Signaling in Hepatocellular Carcinoma.
Asakura N, Nakamura N, Muroi A, Nojima Y, Yamashita T, Kaneko S, Ikeda K, Koshikawa N, Suzuki T
International journal of molecular sciences 2021 Aug 11;22(16)
International journal of molecular sciences 2021 Aug 11;22(16)
Near-infrared-driven fluorescent nanomotors for detection of circulating tumor cells in whole blood.
Xu P, Yu Y, Li T, Chen H, Wang Q, Wang M, Wan M, Mao C
Analytica chimica acta 2020 Sep 8;1129:60-68
Analytica chimica acta 2020 Sep 8;1129:60-68
Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma.
Chen Z, Zhou L, Liu L, Hou Y, Xiong M, Yang Y, Hu J, Chen K
Nature communications 2020 Oct 8;11(1):5077
Nature communications 2020 Oct 8;11(1):5077
Cross-talk between the gut microbiota and monocyte-like macrophages mediates an inflammatory response to promote colitis-associated tumourigenesis.
Yang Y, Li L, Xu C, Wang Y, Wang Z, Chen M, Jiang Z, Pan J, Yang C, Li X, Song K, Yan J, Xie W, Wu X, Chen Z, Yuan Y, Zheng S, Yan J, Huang J, Qiu F
Gut 2020 Oct 29;70(8):1495-506
Gut 2020 Oct 29;70(8):1495-506
MiR-7 reduces the BCSC subset by inhibiting XIST to modulate the miR-92b/Slug/ESA axis and inhibit tumor growth.
Li M, Pan M, You C, Zhao F, Wu D, Guo M, Xu H, Shi F, Zheng D, Dou J
Breast cancer research : BCR 2020 Mar 6;22(1):26
Breast cancer research : BCR 2020 Mar 6;22(1):26
Hedgehog signaling promotes sorafenib resistance in hepatocellular carcinoma patient-derived organoids.
Wang S, Wang Y, Xun X, Zhang C, Xiang X, Cheng Q, Hu S, Li Z, Zhu J
Journal of experimental & clinical cancer research : CR 2020 Jan 28;39(1):22
Journal of experimental & clinical cancer research : CR 2020 Jan 28;39(1):22
Tumor-cell detection, labeling and phenotyping with an electron-doped bifunctional signal-amplifier.
Lu H, Jin D, Zhu L, Guo T, Li X, Peng XX, Mo G, Tang L, Zhang GJ, Yang F
Biosensors & bioelectronics 2020 Dec 15;170:112662
Biosensors & bioelectronics 2020 Dec 15;170:112662
miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis.
Shi DM, Shi XL, Xing KL, Zhou HX, Lu LL, Wu WZ
Cellular signalling 2020 Aug;72:109650
Cellular signalling 2020 Aug;72:109650
In Vivo Study on the Effects of Xiaoaiping on the Stemness of Hepatocellular Carcinoma Cells.
Zhan J, Shi LL, Wang Y, Wei B, Yang SL
Evidence-based complementary and alternative medicine : eCAM 2019;2019:4738243
Evidence-based complementary and alternative medicine : eCAM 2019;2019:4738243
Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine.
Kawaguchi M, Yamamoto K, Takeda N, Fukushima T, Yamashita F, Sato K, Kitamura K, Hippo Y, Janetka JW, Kataoka H
Communications biology 2019;2:11
Communications biology 2019;2:11
High CCL7 expression is associated with migration, invasion and bone metastasis of non-small cell lung cancer cells.
Han S, Wang T, Chen Y, Han Z, Guo L, Wu Z, Yan W, Wei H, Liu T, Zhao J, Zhou W, Yang X, Xiao J
American journal of translational research 2019;11(1):442-452
American journal of translational research 2019;11(1):442-452
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Zhang Q, Cao WS, Wang XQ, Zhang M, Lu XM, Chen JQ, Chen Y, Ge MM, Zhong CY, Han HY
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
Xie C, Zhu J, Wang X, Chen J, Geng S, Wu J, Zhong C, Li X
Journal of experimental & clinical cancer research : CR 2019 Jan 28;38(1):39
Journal of experimental & clinical cancer research : CR 2019 Jan 28;38(1):39
Deglycosylation of epithelial cell adhesion molecule affects epithelial to mesenchymal transition in breast cancer cells.
Liu X, Yang L, Zhang D, Liu T, Yan Q, Yang X
Journal of cellular physiology 2019 Apr;234(4):4504-4514
Journal of cellular physiology 2019 Apr;234(4):4504-4514
Curcumin attenuates resistance to irinotecan via induction of apoptosis of cancer stem cells in chemoresistant colon cancer cells.
Su P, Yang Y, Wang G, Chen X, Ju Y
International journal of oncology 2018 Sep;53(3):1343-1353
International journal of oncology 2018 Sep;53(3):1343-1353
A simple microdevice for single cell capture, array, release, and fast staining using oscillatory method.
Cheng D, Yu Y, Han C, Cao M, Yang G, Liu J, Chen X, Peng Z
Biomicrofluidics 2018 May;12(3):034105
Biomicrofluidics 2018 May;12(3):034105
Tropism of liver epithelial cells toward hepatocellular carcinoma in vitro and in vivo with altering gene expression of cancer stem cells.
Jeng KS, Jeng CJ, Jeng WJ, Sheen IS, Li SY, Lu SJ, Chang CF
American journal of surgery 2018 Apr;215(4):735-743
American journal of surgery 2018 Apr;215(4):735-743
EpCAM and COX‑2 expression are positively correlated in human breast cancer.
Gao S, Sun Y, Liu X, Zhang D, Yang X
Molecular medicine reports 2017 Jun;15(6):3755-3760
Molecular medicine reports 2017 Jun;15(6):3755-3760
Bufalin suppresses cancer stem-like cells in gemcitabine-resistant pancreatic cancer cells via Hedgehog signaling.
Wang H, Ning Z, Li Y, Zhu X, Meng Z
Molecular medicine reports 2016 Sep;14(3):1907-14
Molecular medicine reports 2016 Sep;14(3):1907-14
Liver epithelial cells inhibit proliferation and invasiveness of hepatoma cells.
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Oncology reports 2016 Mar;35(3):1622-8
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EpCAM expression in breast cancer cells is associated with enhanced bone metastasis formation.
Hiraga T, Ito S, Nakamura H
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High LIN28A Expressing Ovarian Cancer Cells Secrete Exosomes That Induce Invasion and Migration in HEK293 Cells.
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BioMed research international 2015;2015:701390
ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis.
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Cell reports 2015 Mar 10;10(9):1599-1613
Cell reports 2015 Mar 10;10(9):1599-1613
Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.
Xu C, Fillmore CM, Koyama S, Wu H, Zhao Y, Chen Z, Herter-Sprie GS, Akbay EA, Tchaicha JH, Altabef A, Reibel JB, Walton Z, Ji H, Watanabe H, Jänne PA, Castrillon DH, Rustgi AK, Bass AJ, Freeman GJ, Padera RF, Dranoff G, Hammerman PS, Kim CF, Wong KK
Cancer cell 2014 May 12;25(5):590-604
Cancer cell 2014 May 12;25(5):590-604
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K
Journal of proteomics 2013 Mar 27;80:171-82
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The American journal of pathology 2012 Dec;181(6):2094-104
The American journal of pathology 2012 Dec;181(6):2094-104
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A431 cells were subjected to SDS PAGE followed by western blot with 21050-1-AP(EPCAM antibody) at dilution of 1:200
- Sample type
- cell line
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EPCAM antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human EPCAM. This antibody recognizes human, mouse antigen. The EPCAM antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 21050-1-AP(EPCAM antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue