BMS171

antibody from Invitrogen Antibodies
Targeting: EPCAM 17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1
Provider product page for BMS171
Western blot
Immunoprecipitation
Immunohistochemistry
Flow cytometry
Other assay

Antibody data

Product number
BMS171 - Provider product page
Provider
Invitrogen Antibodies
Product name
CD326 (EpCAM) Monoclonal Antibody (VU-1D9), eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: BMS171 (VU-1D9) specifically reacts with human Ep-CAM, a 40kD epithelial protein expressed on baso-lateral cell surface in many epithelial tissues (but absent from mesothelial tissues). BMS171 differentiates between mesothelioma and carcinoma, a common diagnostic problem. EpCAM-1 is a homophilic and Ca2+ independent adhesion molecule that is expressed on the baso-lateral cell surface of many epithelial, but not mesothelial tissues. It is expressed de novo in squamous cell carcinoma but is absent in the majority of healthy squamous epithelia. EpCAM expression correlates with cell proliferation, dedifferentiation, and the progression of tumorigenicity. Applications Tested: Flow Cytometry, Functional Studies (Blocking), Immunohistochemistry (Frozen, Paraffin), Immunoprecipitation, Western Blotting.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
VU-1D9
Vial size
100 µg
Concentration
1 mg/mL
Storage
4° C
EPCAM protein structure - BMS171 shown in red.