324201

antibody from BioLegend
Targeting: EPCAM 17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1
Provider product page for 324201
Immunocytochemistry
Flow cytometry

Antibody data

Product number
324201 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#324201, RRID:AB_756075
Product name
Purified anti-human CD326 (Ep-CAM)
Antibody type
Monoclonal
Antigen
DU.4475 breast carcinoma
Description
CD326 is known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40kD protein is highly expressed in the bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. The CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
EPCAM protein structure - 324201 shown in red.