RA0214

antibody from Oursmab
Targeting: EPCAM 17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1
Provider product page for RA0214
Western blot
ELISA
Immunocytochemistry
Flow cytometry
Functional assay

Antibody data

Product number
RA0214 - Provider product page
Provider
Oursmab
Product name
Adecatumumab (Biosimilar Reference Antibody) (EPCAM)
Antibody type
Monoclonal
Description
Adecatumumab is a recombinant, fully human IgG1 monoclonal antibody that targets the Epithelial Cell Adhesion Molecule (EpCAM). It was developed as an anti-cancer therapeutic, primarily for EpCAM-positive solid tumors such as prostate and breast cancer. Its proposed mechanism of action is two-fold: direct inhibition of tumor cell signaling and proliferation via EpCAM blockade, and induction of antibody-dependent cellular cytotoxicity (ADCC) to recruit immune cells for tumor cell killing. Clinical development advanced to Phase II trials, but further progression was discontinued.
Reactivity
Human
Isotype
IgG
Vial size
100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg
Concentration
Bottled at the concentration indicated on the vial.
Storage
Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.
EPCAM protein structure - RA0214 shown in red.