PAB18246

antibody from Abnova Corporation

Targeting: MAP2K1 MAPKK1, MEK1, PRKMK1

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB18246

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB18246, RRID:AB_10715266

Product name

MAP2K1 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of MAP2K1.

Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype.

Murakami S, Balmes G, McKinney S, Zhang Z, Givol D, de Crombrugghe B
Genes & development 2004 Feb 1;18(3):290-305

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Ubiquitin (UbC) expression in muscle cells is increased by glucocorticoids through a mechanism involving Sp1 and MEK1.

Marinovic AC, Zheng B, Mitch WE, Price SR
The Journal of biological chemistry 2002 May 10;277(19):16673-81

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Wnt1 and MEK1 cooperate to promote cyclin D1 accumulation and cellular transformation.

Rimerman RA, Gellert-Randleman A, Diehl JA
The Journal of biological chemistry 2000 May 12;275(19):14736-42

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of extracts from NIH/3T3 cells, treated with PMA (250 ng/mL, 5 mins), using MAP2K1 polyclonal antibody (Cat # PAB18246).Peptide "+" means "peptide blocking".

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MAP2K1 polyclonal antibody (Cat # PAB18246).Peptide "+" means "peptide blocking".

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)