Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB18246 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB18246, RRID:AB_10715266
- Product name
- MAP2K1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of MAP2K1.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype.
Ubiquitin (UbC) expression in muscle cells is increased by glucocorticoids through a mechanism involving Sp1 and MEK1.
Wnt1 and MEK1 cooperate to promote cyclin D1 accumulation and cellular transformation.
Murakami S, Balmes G, McKinney S, Zhang Z, Givol D, de Crombrugghe B
Genes & development 2004 Feb 1;18(3):290-305
Genes & development 2004 Feb 1;18(3):290-305
Ubiquitin (UbC) expression in muscle cells is increased by glucocorticoids through a mechanism involving Sp1 and MEK1.
Marinovic AC, Zheng B, Mitch WE, Price SR
The Journal of biological chemistry 2002 May 10;277(19):16673-81
The Journal of biological chemistry 2002 May 10;277(19):16673-81
Wnt1 and MEK1 cooperate to promote cyclin D1 accumulation and cellular transformation.
Rimerman RA, Gellert-Randleman A, Diehl JA
The Journal of biological chemistry 2000 May 12;275(19):14736-42
The Journal of biological chemistry 2000 May 12;275(19):14736-42
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from NIH/3T3 cells, treated with PMA (250 ng/mL, 5 mins), using MAP2K1 polyclonal antibody (Cat # PAB18246).Peptide "+" means "peptide blocking".
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MAP2K1 polyclonal antibody (Cat # PAB18246).Peptide "+" means "peptide blocking".
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)