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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Product number
- ABIN197389 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) (Ser221) antibody
- Antibody type
- Polyclonal
- Description
- Immunoaffinity chromatography.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- Ser221
- Vial size
- 50 μL
- Storage
- Store the antibody (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia.
Phosphorylation of threonine 290 in the activation loop of Tpl2/Cot is necessary but not sufficient for kinase activity.
MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells.
Zebisch A, Staber PB, Delavar A, Bodner C, Hiden K, Fischereder K, Janakiraman M, Linkesch W, Auner HW, Emberger W, Windpassinger C, Schimek MG, Hoefler G, Troppmair J, Sill H
Cancer research 2006 Apr 1;66(7):3401-8
Cancer research 2006 Apr 1;66(7):3401-8
Phosphorylation of threonine 290 in the activation loop of Tpl2/Cot is necessary but not sufficient for kinase activity.
Luciano BS, Hsu S, Channavajhala PL, Lin LL, Cuozzo JW
The Journal of biological chemistry 2004 Dec 10;279(50):52117-23
The Journal of biological chemistry 2004 Dec 10;279(50):52117-23
MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells.
Wang X, Jin DY, Wong HL, Feng H, Wong YC, Tsao SW
Oncogene 2003 Jan 9;22(1):109-16
Oncogene 2003 Jan 9;22(1):109-16
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